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Nihon Naika Gakkai Zasshi
Maruyama et al. have systematically studied comb-type copolymers, dextrangrafted poly(lysine). ... Cellular uptake of these complexes and those transfections are now in progress and will be reported in our forthcoming paper. this article: Tooru Ooya et al 2004 Sci. Technol. Adv. ...doi:10.1016/j.stam.2003.12.014 fatcat:bdev27h3bngonffu4xhvtagtsa
In an earlier paper, experimental results of the infiltration phenomena were reported. In this paper, using the data of the earlier paper, the infiltration phenomena are discussed physically.doi:10.11408/jsidre1965.1976.63_15 fatcat:zdtbv2s46fc3vjkko3hpzpg3pq
., MARUYAMA, K. and ORII, T. Metabolism of Sphingomyelin in Cultured Skin Fibroblasts from Patients with Different Types of Niemann-Pick Disease. Tohoku J. exp. ...doi:10.1620/tjem.148.365 pmid:3738903 fatcat:d3sovn262ba37k7u3sqhmz6wkq
A 45-year-old woman with a long-standing diagnosis of tuberous sclerosis (TSC) is presented. She has multifocal micronodular pneumocyte hyperplasia (MMPH) and lymphangioleiomyomatosis (LAM) of the lung, together with the detection of TSC2 gene mutation. During surgery for spontaneous pneumothorax, an open-lung biopsy was performed. Micronodules were well defined, measuring approximately 4 mm in diameter. These MMPHs were histologically composed of papillary proliferation of Type II pneumocytes,doi:10.1038/modpathol.3880359 pmid:11406664 fatcat:iqzjrj645ndnbclejw2qfphbxy
more »... with positive immunoreactivity of keratin and surfactant apoprotein. The cystlike spaces, with dilatation and destruction of air spaces, were diffusely formed, and the walls were composed of the spindle cells. Such LAM showed positive immunoreactivity for HMB-45 (a monoclonal antibody specific for human melanoma) and tuberin (the gene product of TSC2). On germline mutation analysis using leukocytes of the present patient, a TSC2 gene mutation was confirmed as a deletion of G (or g) on Exon 9 by polymerase chain reaction-single-strand conformational polymorphism. However, no mutation was detected in her son. With microdissection analysis using paraffinembedding lung tissues, LOH of the TSC2 gene preliminarily was detected in a LAM lesion but not in MMPH. It is suggested that MMPH, in addition to LAM, could be another pulmonary lesion in TSC patients and that the detection of TSC2 and/or TSC1 gene could essentially be useful for the pathogenesis of MMPH and LAM in TSC patients. KEY WORDS: Loss of heterozygosity (LOH), Lymphangioleiomyomatosis (LAM), Multifocal micronodular pneumocyte hyperplasia (MMPH), PCR-SSCP, TSC2 gene, Tuberin, Tuberous sclerosis (TSC).
The Japanese Journal of Antibiotics
CTM was administered at dose levels of 1 to 3g a day to 77 cases of otorhinolaryngological infections, and the following results were obtained: 1. The effect of the drug was determined in 75 cases . The responders were 3 out of 5 (60.0%) in acute suppurative otitis media, 4 out of 11 (36 .4%) in chronic suppurative otitis media, 39 out of 43 (90.7%) in tonsillitis and peritonsillar abscess and 12 out of 16 (75.0%) in other diseases , a total of 58 out of 75 cases (77.3%). 2. The bacteriologicaldoi:10.11553/antibiotics1968b.36.2693 fatcat:vkz5qeyicffubhq3pcpljznls4
more »... effect of CTM was evaluated in 53 cases , and bacterial eradication wasd emonstrated in 41 cases (77.4%). Also, its antibacterial potency was 2 to 4 times superior in comparison to that of CEZ against isolated bacteria in which MICs were measurable. 3. Side effects which were neither severe nor specific were recognized in 3 out of 77 cases (3 .9%). In the cases with abnormal laboratory values , none was determinable to be attributed to CTM.
膵 臓 27 巻 2 号(2012) 28：120 Japanese guideline for abstinence and lifestyle in patients with chronic pancreatitis: problems and landscape Taichi NAKAMURA, Tetsuhide ITO １) , Katsuya MARUYAMA ２) , and Tooru ...doi:10.2958/suizo.27.113 fatcat:csx4hy46yffrjdggm7aeksig5q
New resist, under layer, and topcoat materials specific to EUVL was developed and investigated for sub 20 nm hp patterning performance. High Tg resin and high absorption resin were developed and incorporated in to EUV resist. EUV resist including high Tg resin showed good LWR and local CD uniformity (LCDU). EUV resist containing high absorption resin showed higher resist sensitivity. New silicon type under-layer materials with different hydrophobicity were developed for further patterningdoi:10.2494/photopolymer.26.691 fatcat:eqs7rd6przantisp4ltfl2sx6u
more »... mance improvement. Silicon type under-layer material with higher hydrophobic surface property improved line collapse margin which in turn improved resist resolution. EUV top-coat material was developed and examined for EUV resist sensitivity to out of band (OOB) radiation. EUV top-coat suppressed OOB influence and improved lithographic performance. EUV resist containing new materials resolved 15 nm half pitch lines and spaces and 20 nm contact hole patterns.
Transactions of The Japanese Society of Irrigation, Drainage and Reclamation Engineering
This paper presents an attempt to determine the best way to use water in dynamic irrigation. Simulations were carried out using different quantities of water each instance of irrigation (1/3 130, 2/3 I30 and full irrigation) and different soil textures (sand, sandy loam, loam, and clay) to come to an understanding of the mechanism for saving water. A dynamic numerical model, based on the consumption-transport-retention of water, was designed so as to compute the diurnal fluctuation of waterdoi:10.11408/jsidre1965.1983.108_1 fatcat:vwnfk57pczc5rezdk3q4r53cai
more »... ntial in soil layers and evaporation under various characteristics. The results are follows. (1) Because of the suppression of water movement and evaporation at dry and wet stages, the amount of evaporation for one year period decreased more when little water was used for irrigation instead of much and when sandy loam and loam were used more than sand and clay.
The Japanese Journal of Gastroenterological Surgery
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