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Orexigenic action of oral zinc: metabolomic analysis in the rat hypothalamus
2018
Figshare
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We previously reported an orexigenic action of oral zinc administration in male Sprague-Dawley (SD) rats during an early stage of feeding with a zinc-deficient diet, without decreased zinc concentrations in tissues. The overall conclusion was that orally but not intraperitoneally administered zinc stimulates food intake in short-term zinc-deficient-diet fed rats. We here investigate the mechanism of the orexigenic action of zinc using GC-MS/MS-targeted metabolomic analysis in the rat
doi:10.6084/m9.figshare.7119509.v1
fatcat:z2mb5c25jfhyppo6ncym4s5spq
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... s. Four-week-old, male SD/Slc rats were used, and after 2 days of feeding with a zinc-deficient diet, 3 mg of ZnSO4 in 5 mL saline solution were administered to each rat either orally or intraperitoneally. Three hours after administration, the rats were sacrificed and the hypothalamus were excised and analyzed. We found that the oral administration group showed increased concentrations of 3-aminopropanoic acid (β-alanine), hypotaurine, dopamine, and biotin. In light of metabolomic analysis of these results, we indicate directions for further research. Plot of the results of an OPLS-DA for Zn-PO (oral) and Zn-IP (intraperitoneal) groups, and S-plot by OPLS-DA revealed several metabolites were increased in the hypothalamus by Zn-PO.
Expression in Cereal Plants of Genes That InactivateFusariumMycotoxins
2003
Bioscience, biotechnology and biochemistry
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Trichothecene 3-O-acetyltransferase (encoded by Tri101) inactivates the virulence factor of the cereal pathogen Fusarium graminearum. Zearalenone hydrolase (encoded by zhd101) detoxiˆes the oestrogenic mycotoxin produced by the same pathogen. These genes were introduced into a model monocotyledon rice plant to evaluate their usefulness for decontamination of mycotoxins. The strong and constitutive rice Act1 promoter did not cause accumulation of TRI101 protein in transgenic rice plants. In
doi:10.1271/bbb.67.914
pmid:12784641
fatcat:wtclxcesafgkhdu35mumuegtau
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... ast, the same promoter was suitable for transgenic production of ZHD101 protein; so far,ˆve promising T0 plants have been generated. Low transgenic expression of Tri101 was suggested to be increased by addition of an Q enhancer sequence upstream of the start codon.
Correlation between Alcohol-Based Handrub Consumption and Adherence to Hand Hygiene Protocols in Individual Nurses
2018
International Archives of Nursing and Health Care
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Hand hygiene helps prevent health careassociated infections. Prior studies have investigated methods to measure adherence to hand hygiene protocols and have attempted to determine the correlation between alcohol-based handrub consumption and hand hygiene adherence via direct observation in healthcare facilities or wards, but there remains need for methods measuring hand hygiene adherence in individual health care workers. The failure of even one worker to adhere to the hand hygiene protocols
doi:10.23937/2469-5823/1510111
fatcat:jzobyzz7bveupllt7fev54tzbu
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... increase the risk of infection. We aimed to examine the correlation between alcohol-based handrub consumption and adherence to hand hygiene protocols by direct observation in individual nurses. Methods: We surveyed regarding alcohol-based handrub consumption and directly observed 17 nurses engage in hand hygiene practices at the University hospital in Japan. Results: There was a significant, positive and moderate correlation between alcohol-based handrub consumption among day shift nurses (mL/patient-day) and the rate of adherence to hand hygiene protocols (%) on direct observation [r = 0.543 (p = 0.045)]. Conclusion: Alcohol-based handrub consumption per patient-day during the day shift can be used to validate direct observation compliance rates of hand hygiene activities among individual nurses.
Prehospital intravenous access for survival from out-of-hospital cardiac arrest: propensity score matched analyses from a population-based cohort study in Osaka, Japan
2017
BMJ Open
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, 2 Kentaro Kajino, 3 Kosuke Kiyohara, 4 Chika Nishiyama, 5 Tatsuya Nishiuchi, 6 Yasuyuki Hayashi, 7 Takashi Kawamura, 8 Taku Iwami 8 To cite: Fujii T, Kitamura
Open Access Usually, ...
Prehospital intravenous access for survival from out-of-hospital cardiac arrest: propensity score matched analyses from a population-based cohort study in Osaka, Japan Tomoko Fujii, 1 Tetsuhisa Kitamura ...
doi:10.1136/bmjopen-2016-015055
pmid:29197833
pmcid:PMC5719330
fatcat:l262wlme7rg7hexl65upx3xca4
Improvement of Cardiac Diastolic Function and Prognosis After Autologous Peripheral Blood Stem Cell Transplantation in AL Cardiac Amyloidosis
2007
Internal medicine (Tokyo. 1992)
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AL amyloidosis is a disease in which immunoglobulin L chain is deposited in multiple organs, and the prognosis of cardiac amyloidosis is extremely poor. Although several treatments based on that for multiple myeloma, have been performed, there is no clear evidence that cardiac function is improved. We report a case of AL cardiac amyloidosis with moderate cardiac dysfunction for which we performed autologous peripheral blood stem cell transplantation (auto-PBSCT) in combination with high-dose
doi:10.2169/internalmedicine.46.0142
pmid:17938525
fatcat:bqmokrogwja4zhxasu7e2rryzi
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... phalan therapy. This treatment resulted in significant improvement in cardiac function and good prognosis for about 3.5 years after the diagnosis. Therefore, auto-PBSCT is a possible option as up-front therapy for AL cardiac amyloidosis. A 63-year-old woman visited a hospital because of palpitation in 2002. A 12-lead electrocardiography (ECG) revealed first-degree atrioventricular block and low voltage in the limb lead. Multifocal premature ventricular contractions were observed on a 24-
Successful Treatment of Cytomegalovirus Retinitis in a Child with Acute Lymphoblastic Leukemia during Maintenance Chemotherapy
急性リンパ性白血病の維持療法中に合併したサイトメガロウイルス網膜炎の1例
2002
The Japanese Journal of Pediatric Hematology
急性リンパ性白血病の維持療法中に合併したサイトメガロウイルス網膜炎の1例
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し か し急 性 リ ンパ 性 白血 病 (ALL)の 維 持 療 法 中 は 一 般 に免 疫 抑 制 は 強 度 で は な く, 2002年5月7日 受 付,2002年7月22日 受 理 別 刷 請 求 先:〒700-8558岡 山 市 鹿 田 町2-5-1岡 山 大 学 大 学 院 医 歯 学 総 合 研 究 科 小 児 医 科 学 浦 上 知 子 Reprint requests to Tomoko ...
doi:10.11412/jjph1987.16.312
fatcat:ksr5vbqfjnc7dnubz6zy6bg7zy
Successful treatment of direct hemoperfusion with polymyxin B-immobilized fiber for septic shock and severe acute kidney injury due to ceftriaxone-resistant Escherichia coli: a case report with literature review
2020
Renal Replacement Therapy
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Septic shock is a life-threatening condition and one of the most common causes of acute kidney injury. Polymyxin B-immobilized fiber column direct hemoperfusion (PMX-DHP) is used to reduce endotoxin levels in blood. Here, we report a rare but important case of sepsis-induced acute kidney injury and septic shock, which was successfully treated with PMX-DHP in spite of inappropriate initial antibiotic therapy. Case presentation: An 84-year-old man was hospitalized for septic shock and acute
doi:10.1186/s41100-020-00266-z
fatcat:2mbpdlwq5rakpk2gqdfa42yfha
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... injury. Although he was treated with ceftriaxone, he did not recover from hypotension and had reduced urine output. After initiating PMX-DHP on days 3 and 4, his blood pressure was immediately elevated and his white blood cell count and Creactive protein levels improved. Because ceftriaxone-resistant Escherichia coli was identified in blood culture, we changed his antibiotics to levofloxacin on day 7. He successfully recovered from the septic shock and dialysis was withdrawn. Conclusions: Considering the use of inappropriate initial antibiotics, the early induction of PMX-DHP might have been a key determinant of his outcome. PMX-DHP therapy should be considered in septic shock in addition to antibiotic treatment.
An exploratory study regarding the mental and physical functions and the background characteristics related to non-participation and dropouts in a longitudinal study of community-dwelling elderly
地域在住高齢者における縦断的調査への不参加および途中脱落に関連する心身機能と背景因子の探索
2016
Japanese journal of physical fitness and sports
地域在住高齢者における縦断的調査への不参加および途中脱落に関連する心身機能と背景因子の探索
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The purpose of the present study was to investigate the baseline characteristics related to the participation status in a longitudinal epidemiological study for the elderly. Nine hundred twenty-six self-supporting older adults lived in a local city located southwest in Japan were classified into the following 3 groups; non-participants (NP, n=170), participants for the baseline measurements (PB, n=278), and participants for both the baseline and follow-up measurements after two-years (PBF,
doi:10.7600/jspfsm.65.315
fatcat:26bw7kcipreargla4lanbmmdqe
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... ). The basic attributes including socioeconomic status, depressive symptoms, cognitive function, sleep quality, fitness, objectively-measured physical activity, habitual behavior, psychosocial characteristics and functional problems in daily life were assessed. Regarding the NP group, data were collected by questionnaire or home visits. According to the results of a multinomial logistic regression analysis adjusted for age, sex and years of education, significant odds ratios which indicate a poor status in most of the assessment items were observed in both the NP and PB groups in comparison to the PBF group. We concluded that sex (female), a higher age, fewer years of education, a cognitive function decline, depressive symptoms, a low fitness level, physical activity and daily living function, and poor psychosocial backgrounds were related to the non-participation and dropouts. These results should be considered in a longitudinal data analysis of the present study, as well as in the design setting of epidemiological studies dealing with physical activity indexes and care risk factors. Furthermore, these findings are also considered to be useful as basic data for such care prevention activities in the community.
Index
2021
Nippon Saikingaku Zasshi
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092
Nishikino, Tatsuro
錦野 達郎
EWS1-2
〃
ODP-065
Nishimori, Asami
西森 朝海
JRS-7
Nishimura, Akira
西村 明
WS6-5/ODP-078
〃
ODP-077
〃
ODP-080
〃
ODP-158
Nishino, Kunihiko
西野 邦彦
S11-1
Nishiuchi ...
茂幸
ODP-211
Hamaguchi, Kanta
濱口 幹太
ODP-024
Hamahata, Takeshi
濱端 崇
WS7-8/ODP-126
Hamano, Kimikazu
濱野 公一
ODP-217
Hamauzu, Ryoko
濱渦 亮子
ODP-079
Hanaki, Hideaki
花木 秀明
ODP-004
Hanawa, Tomoko ...
doi:10.3412/jsb.76.129
pmid:33627528
fatcat:ri66tv7vbvcyvcw2xktocuv2im
CONTENTS OF VOLUME 77, 2013
2013
Circulation Journal
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Significant Improvement of Left Atrial and Left Atrial Appendage Function After Catheter Ablation for Persistent Atrial
Fibrillation
Tomoko Machino-Ohtsuka, Yoshihiro Seo, Tomoko Ishizu, Satomi Yanaka ...
Application of 3-Dimensional Speckle Tracking Imaging to the Assessment of Right Ventricular Regional Deformation
Akiko Atsumi, Tomoko Ishizu, Yuri Kameda, Masayoshi Yamamoto, Yoshie Harimura, Tomoko ...
doi:10.1253/circj.cj-77-12-index_1
fatcat:sc7qtl6pifdxfnlso2mubjqdiq
Index
2018
Nippon Saikingaku Zasshi
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Nishikino, Tatasuro
錦野 達郎
P-129
Nishimura, Akira
西村 明
P-125
〃
P-271
〃
P-281
Nishimura, Masahiro 西村 昌洋
P-202
Nishimura, Ryutaro
西村 隆太郎 WS4-6 (P-220)
Nishimura, Tomoya
西村 知泰
P-118
Nishiuchi ...
大庭 良介
P-201
Ohno, Hiroshi
大野 博司
P-106
Ohno, Kinji
大野 欽司
S1-4
Ohno, Yuka
大野 由香
P-102
Ohsawa, Hiroyoshi
大澤 弘宜
P-328
Ohshima, Tomoko
大島 朋子
P-342
Ohsugi, Mitsuru
大杉 満
WS9-1 (P-099) ...
doi:10.3412/jsb.73.156
pmid:29479021
fatcat:lpjvphrpovbrjlw6ni2kxtu344
Index
2019
Nippon Saikingaku Zasshi
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村田 武士 DP03-09 (P-283) Muto, Naoki 武藤 真輝 DP24-09 (P-333) DP04-14 (P-215) 〃 DP05-04 (P-111) 〃 DP18-01 (P-162) 〃 DP18-04 (P-166) Ryutaro 西村 隆太郎 DP15-08 (P-175) Nishitani, Yoshihiro 西谷 佳浩 DP04-04 (P-158) Nishiuchi ...
, Takashi
杉田 隆
S08-03
〃
DP23-12 (P-040)
〃
DP24-05 (P-272)
Sugiura, Yuki
杉浦 悠毅
DP14-04 (P-236)
Sugiyama, Toshiro
杉山 敏郎
DP20-06 (P-057)
Sumi, Masato
鷲見 優斗 DP02-10 (P-074)
Sumitomo, Tomoko ...
doi:10.3412/jsb.74.143
fatcat:yvmlgo2w75cbrg2ivwycsl6sra
Global Prevalence of Domestic Cat Hepadnavirus: An Emerging Threat to Cats' Health?
2022
Frontiers in Microbiology
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ACKNOWLEDGMENTS We thank Tomoko Nishiuchi for her support. Figure 1 and Figure 4 were created with BioRender (https:// biorender.com/). ...
doi:10.3389/fmicb.2022.938154
pmid:35814669
pmcid:PMC9263588
fatcat:dv2j4hpyczabbefka7p5lzt7t4
CONTENTS OF VOLUME 75, 2011
2011
Circulation Journal
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Assist Device -Single Center's Experience in Japan -
Ikutaro Nakajima, Tomoko S. ...
, Tomoko Machino, Haruhiko Higuchi, Junji Shiotsuka, Yuichi Noguchi, Kazutaka Aonuma ········ 1934 173. ...
doi:10.1253/circj.cj-75-12-index_1
fatcat:hyupe3wu5ffjhcthwnvk2yrvfy
The Fifty-Sixth Annual Meeting of the Population Association of Japan
2004
Jinkogaku kenkyu
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g e me n t s a n d We l l -Be i n g o f t h e E l d e r l y i n Ba n g k o k , Th a i l a n d MORIKI, Yoshie ( P e n n s y l v a n i a S t a t e Un i v e r s i t y ) ……………………………………………………… C h a i r > NISHIUCHI ...
………………………………………………………… 3 .F a mi l y P l a n n i n g a n d P r e v e n t i o n o f S e x u a l l y Tr a n s mi t t e d Di s e a s e s :Ne w Ap p r o a c h e s i n He a l t h P r o mo t i o n SAOTOME, Tomoko ...
doi:10.24454/jps.35.0_100
fatcat:p4js4a4lurfsxls7ybb3umtm4e
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