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Comparison of Component Frameworks for Real-Time Embedded Systems [chapter]

Petr Hošek, Tomáš Pop, Tomáš Bureš, Petr Hnětynka, Michal Malohlava
2010 Lecture Notes in Computer Science  
The usage of components brings significant help in development of real-time embedded systems. There have been a number of component frameworks developed for this purpose and some of them have already become well-established in this area. However, although the component frameworks share basic concepts and the general approach, they substantially differ in the range of supported features and maturity. This makes relatively difficult to select the right component framework and thus poses a
more » ... ant obstacle in adoption of the component-based development for real-time embedded systems. To provide an overview, we present a survey in this paper, which illustrates distinguishing features of selected modern component-based frameworks for real-time embedded systems. The survey identifies features which are important for building systems from components in this area and compares these frameworks with respect to these features.
doi:10.1007/978-3-642-13238-4_2 fatcat:4b6yw6rksrd53cec5mudzwwgiq

Comparison of component frameworks for real-time embedded systems

Tomáš Pop, Petr Hnětynka, Petr Hošek, Michal Malohlava, Tomáš Bureš
2013 Knowledge and Information Systems  
The usage of components brings significant help in development of real-time embedded systems. There have been a number of component frameworks developed for this purpose and some of them have already become well-established in this area. However, although the component frameworks share basic concepts and the general approach, they substantially differ in the range of supported features and maturity. This makes relatively difficult to select the right component framework and thus poses a
more » ... ant obstacle in adoption of the component-based development for real-time embedded systems. To provide an overview, we present a survey in this paper, which illustrates distinguishing features of selected modern component-based frameworks for real-time embedded systems. The survey identifies features which are important for building systems from components in this area and compares these frameworks with respect to these features.
doi:10.1007/s10115-013-0627-9 fatcat:4kkale32enbjzec5dbkly2hqdm

ENDOBRONCHIAL ULTRASOUND – ONE YEAR OF EXPERIENCE IN CLINICAL PRACTICE

Marioara Simon, Bogdan Pop, Lacrimioara Toma, Aletta Vallasek, Ioan Simon
2017 Clujul Medical  
and aim. Endobronchial ultrasound (EBUS) is a recent minimally invasive, safe examination method for the mediastinum, with a good diagnostic precision. This method makes possible real time examination with transbronchial fine needle aspiration, diagnostic transbronchial needle aspiration (TBNA) and staging of non-small pulmonary tumors, as well as diagnosis of mediastinal and hilar adenopathies of various causes. Methods. We present the experience of the Bronchoscopy Department of the
more » ... y Clinic of Cluj-Napoca with EBUS-TBNA as a tool for the diagnosis and staging of tumors in contact with the bronchial wall and mediastinal and hilar adenopathies of unknown etiology. During the period August 2014 -January 2016 we examined 152 patients with no direct or indirect signs of lung tumor in traditional bronchoscopy. Rapid on site evaluation (ROSE) was available for all patients. Results. Our study is a retrospective study of 152 EBUS-TBNA examinations. The average age of our patients was 54.43 years and 64% came from urban and 36% from rural background. EBUS-TBNA brought the final histological confirmation (tumors, sarcoidosis, limphoma) in 82.8% of the cases. A tumor confirmation was obtained in 95% of the patients who were suspected of having tumor. For a better understanding of the importance of this method in the daily clinical practice we present a case of peripheral pulmonary neoplasm with mediastinal and hilar adenopathies, where the contribution of EBUS-TBNA to a rapid diagnosis was essential. Conclusion. By the introduction of this method in our country one year ago, we can diagnose patients with lung and mediastinal tumors, which cannot be diagnosed by traditional bronchoscopy. This brings a valuable contribution to the improvement of lung cancer staging and diagnostic.
doi:10.15386/cjmed-655 pmid:28559704 pmcid:PMC5433572 fatcat:aatkivrkdjdlbcx23eci7l5tna

Pop Song Translations by Rolando Tinio as Script and Subversion of the Marcos Regime

Niccolo Rocamora Vitug, Faculty at the University of Santo Tomas and PhD Scholar at the College of Music, University of the Philippines, Quezon City, Philippines.
2022 Rupkatha Journal on Interdisciplinary Studies in Humanities  
The identification of this script will be done by a reading of a representative pop song translation by Tinio, in the context of other materials that elucidate the script of the time—from the former first  ...  The following are the programs for the two Pop Songs concerts, of which Celeste Legaspi was the vocalist while Willy Cruz was the accompanying artist on November 8, 1975 and March 9, 1976, respectively  ... 
doi:10.21659/rupkatha.v14n1.17 fatcat:s3yncdn2obfvlof6jalundesne

EBUS in optimizing non-small cell lung cancer diagnosis and treatment

Antonia Haranguş, Ioana Berindan-Neagoe, Lăcrămioara Toma, Ioan Şimon, Ovidiu Pop, Mărioara Şimon
2021 Medicine and Pharmacy Reports  
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a commonly used minimally invasive method for the diagnosis and staging of lung cancer. In order to improve its diagnostic accuracy, rapid on-site cytologic evaluation (ROSE) is being utilized in some institutions. ROSE, performed by a cytopathologist in the examination room, allows the assessment of the adequacy of the collected samples, identifies malignant cells and sometimes establishes diagnosis on the spot,
more » ... s improving diagnostic sensitivity. As non-small cell lung carcinomas (NSCLC) require not only pathological subtyping, but also molecular characterization, obtaining the adequate amount of tissue is crucial. Only a limited number of studies have analyzed the suitability of EBUS-TBNA samples for assessment of epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK) and programmed death-ligand 1 (PD-L1) status. We intended to examine the diagnostic yield of ROSE in NSCLC and the results and feasibility of molecular analysis performed on EBUS-TBNA small samples. 100 patients with lung tumors and hilar and/or mediastinal lymphadenopathy on CT or PET/CT scans were retrospectively identified over a 3-year period, from a prospectively maintained EBUS-TBNA database. All examinations were accompanied by on-site cytological exam - ROSE, histopathological exam (HPE) and, in the case of NSCLC, molecular testing. After the sampling of the lymph nodes, specimens were Diff-Quik stained and a rapid preliminary diagnosis was established. Immunohistochemistry and mutational testing were performed using cell blocks. Adenocarcinoma was the most frequent diagnosis in both ROSE (34%) and histopathology (53%). Overall sensitivity and positive predictive value of ROSE in NSCLC, considering HPE the gold standard, were 92.18% and 93.65%, respectively, with a specificity and negative predictive value of 75% and 70.58%, respectively. All samples that were tested for EGFR mutation and ALK rearrangement were adequate for analysis. The adequacy ratio for PD-L1 was 91.66%; 37.5% of patients showed a high PD-L1 expression level, with a tumor proportion score TPS ≥50%. EBUS-TBNA is a valuable method for lung cancer diagnosis. ROSE proved to have a moderate prediction of the final diagnosis in NSCLC. Molecular analysis of EGFR, ALK and PD-L1 can be successfully accomplished on EBUS-TBNA small tissue samples.
doi:10.15386/mpr-1725 pmid:34013188 pmcid:PMC8118210 fatcat:nrsgh3syx5hdzd47j55mqbhfny

Automated evaluation of regular lab assignments: A bittersweet experience?

Pavel Jezek, Michal Malohlava, Tomas Pop
2013 2013 26th International Conference on Software Engineering Education and Training (CSEE&T)  
Our undergraduate curriculum includes a one semester course on object-oriented programming in the C# language and the .NET platform. The course underwent a major change in its labs organization two years ago -an introduction of regular one-week lab assignments motivated by a need to enhance unsatisfactory skills of students attending the course. However such change of the course scheme would not be possible without introduction of an automated evaluation system of the lab assignments. Besides
more » ... e expected positive results, we were worried about any unforeseen consequences of the change. Having enough data from before and after the change of the course scheme the paper presents a unique analysis of impact of such a change on students and the course itself. The paper provides two main contributions: (1) to our best knowledge, we provide the first empirical validation of expected impacts on real-world data and (2) we identify and discuss several unexpected aspects and drawbacks of introduction of such a new scheme.
doi:10.1109/cseet.2013.6595256 dblp:conf/csee/JezekMP13 fatcat:xdptipcflbdgjc5s5zz65ylo7u

Analysis of the toxicogenomic effects of exposure to persistent organic pollutants (POPs) in Slovakian girls: Correlations between gene expression and disease risk

Partha Sarathi Mitra, Somiranjan Ghosh, Shizhu Zang, Dean Sonneborn, Irva Hertz-Picciotto, Tomas Trnovec, Lubica Palkovicova, Eva Sovcikova, Svetlana Ghimbovschi, Eric P. Hoffman, Sisir K. Dutta
2012 Environment International  
lower than the concentration of the other major POP constituents.  ...  For the study population, we selected prepubertal girls (mean age of 46.2 ± 1.4 months) with high POP concentrations in their blood (> 75% tile of total POP) and classified them in the high 'PCB' group  ...  Low POP Group (Control): low total POP value in their blood (< 25 percentile).  ... 
doi:10.1016/j.envint.2011.09.003 pmid:22208759 pmcid:PMC3259908 fatcat:nuiliucqajcj7clpbo2o2yswim

HPLC Method Validation for Simultaneous Determination of Three Mycotoxins from Corn Seeds

Augustin Curticapean, Felicia Toma, Monica Tarcea, Manuela Curticapean, Victor Samarghitan, Ioan Aurel Pop, Alin Gulea
2011 Croatica Chemica Acta  
A new HPLC optimized method for simultaneous determination of some mycotoxins by separation and using a Dionex UltiMate3000 modular system, with multichannel UV detector was developed and validated. The method optimization was performed to determine simultaneously, several relevant mycotoxins from corn seeds that were stored over 8 months. The mycotoxins selected for quantification were: aflatoxin B1, ochratoxin A and zearalenone. They were selected due to their high concentration in the
more » ... For the development stages of the HPLC method, it was introduced an internal standard to have accurate results. Taking into account that the analytes should be extracted from the complex matrix they reside, an extraction procedure was performed, using organic solvents, and the selection after repeated tests demonstrated the best capacity for ethyl acetate. The recovery is about 60 -70 % after the extraction process also there is a good preconcentration (×2.5) of the analytes and the internal standard for their quantification. The limit of quantification (LOQ) obtained by chromatographic parameters optimization, for aflatoxin B1 and ochratoxin A were about 3 -5 µg kg -1 and 14.4 µg kg -1 for zearalenone of raw biological material, making these values lower than those accepted by the actual normatives and regulations.
doi:10.5562/cca1788 fatcat:2ri3jbcaf5bsxbrxmkb2co4btm

Plasmonic Hepatitis B Biosensor for the Analysis of Clinical Saliva

Tomáš Riedel, Simone Hageneder, František Surman, Ognen Pop-Georgievski, Christa Noehammer, Manuela Hofner, Eduard Brynda, Cesar Rodriguez-Emmenegger, Jakub Dostálek
2017 Analytical Chemistry  
A biosensor for the detection of hepatitis B antibodies in clinical saliva was developed. Compared to conventional analysis of blood serum, it offers the advantage of noninvasive collection of samples. Detection of biomarkers in saliva imposes two major challenges associated with the low analyte concentration and increased surface fouling. The detection of minute amounts of hepatitis B antibodies was performed by plasmonically amplified fluorescence sandwich immunoassay. To have access to
more » ... ic detection, we prevented the nonspecific adsorption of biomolecules present in saliva by brushes of poly[(N-(2-hydroxypropyl) methacrylamide)-co-(carboxybetaine methacrylamide)] grafted from the gold sensor surface and post modified with hepatitis B surface antigen. Obtained results were validated against the response measured with ELISA at a certified laboratory using serum from the same patients.
doi:10.1021/acs.analchem.6b04432 pmid:28192973 pmcid:PMC5343552 fatcat:rkcncht6njdktdddrq644zuc3q

Structural and optical characterization of Cu doped ZnO thin films deposited by RF magnetron sputtering

Maria Toma, Nicolae Ursulean, Daniel Marconi, Aurel Pop
2019 Journal of Electrical Engineering  
Kogalniceanu No.1, 400084, Cluj-Napoca, Romania, mary02.toma@gmail.com, **Research Center for Advanced Medicine Iuliu Hatieganu University of Medicine and Pharmacy, 400337, Cluj-Napoca, Romania, ***Department  ... 
doi:10.2478/jee-2019-0054 fatcat:fb3vbcsddfakzp3cb7lcyhc3se

Comparative Measurements of Aortic Diameters Using Transthoracic Echocardiography and Thoracic Computed Tomography Angiography in Neonatal Aortic Coarctation

Daniela Toma, Simina-Elena Rusu, Cristina Blesneac, Marian Pop, Rodica Togănel
2017 Journal of Interdisciplinary Medicine  
Background: Critical aortic coarctation is defined as the severe narrowing of the isthmic aortic lumen, representing a neonatal cardiac emergency, part of the congenital heart diseases with duct-dependent systemic circulation. Aim of the study: To assess the correlation between transthoracic echocardiography and computed tomography angiography (CTA) in the measurement of aortic diameters in a group of newborns diagnosed with duct-dependent aortic coarctation and/or associated hypoplastic aortic
more » ... arch. Material and method: We performed a retrospective study on neonates diagnosed with duct-dependent aortic coarctation and/or associated hypoplastic aortic arch between January 1, 2015 and March 1, 2017. The studied parameters were diameters of the aorta at the level of the aortic annulus, coronary sinuses, sinotubular junction, ascending aorta, proximal and distal aortic arch, and the aortic isthmus. Measurements were obtained by transthoracic echocardiography and thoracic CTA. Results: Fifteen newborns diagnosed with duct-dependent aortic coarctation and/or associated hypoplastic aortic arch were included in this study. There was no statistically significant difference between the two imaging methods, the T test highlighting differences only between the measurements of the aortic annulus (p <0.016) and coronary sinuses (p <0.008). The patients included in the study associated other cardiovascular abnormalities: persistent ductus arteriosus (100%), atrial septal defect (100%), aortic arch hypoplasia (80%), bicuspid aortic valve (73.3%). Conclusions: These methods reveal important information on the anatomy of the cardiovascular malformation and its impact on the clinical and paraclinical status of the patient, being fundamental for establishing an optimal therapeutic approach.
doi:10.1515/jim-2017-0058 fatcat:hscysfy74zdjzahjf3k3qtar2u

Bioengineering a pre-vascularized pouch for subsequent islet transplantation using VEGF-loaded polylactide capsules

Naresh Kasoju, Alžběta Pátíková, Edyta Wawrzynska, Alžběta Vojtíšková, Tomáš Sedlačík, Marta Kumorek, Ognen Pop-Georgievski, Eva Sticová, Jan Kříž, Dana Kubies
2019 Biomaterials Science  
The effectiveness of cell transplantation can be improved by optimization of the transplantation site.
doi:10.1039/c9bm01280j pmid:31729495 fatcat:3g47rikxyzbmfleq5p3gz5aija

Integrated taxonomy reveals multiple species in the Dendrobaena byblica (Rosa, 1893) complex (Oligochaeta: Lumbricidae)

TÍmea Szederjesi, Victor V Pop, TomÁŠ PavlÍČek, Orsolya MÁrton, VirÁg KrÍzsik, Csaba Csuzdi
2017 Zoological Journal of the Linnean Society  
Tomas Pavlíček (Institute of Evolution, Universityof Haifa, Israel), for his kind help during preparation of this paper.  ...  MATERIAL and METHOD To determine the earthworm fauna of the two parts of the country, in addition to some new data, Rosa (1893 Rosa ( , 1905 , Michaelsen (1907 Michaelsen ( , 1910 , Pop (1943 ) Omodeo  ... 
doi:10.1093/zoolinnean/zlx049 fatcat:qqyuaaohevajdnxcenriucmusm

The Occurrence of Aflatoxins in Nuts and Dry Nuts Packed in Four Different Plastic Packaging from the Romanian Market

Adrian Maximilian Macri, Ioana Pop, Daniel Simeanu, Diana Toma, Ion Sandu, Liliana Lacramioara Pavel, Olimpia Smaranda Mintas
2020 Microorganisms  
Mycotoxins are secondary metabolites produced by various fungi. A very important category of mycotoxins are aflatoxins, considered to be the most dangerous in humans. Aflatoxin B1, well known as a favorable factor in the occurrence of hepatocellular carcinoma in humans, is the most controversial of all mycotoxins. Aflatoxins, found in naturally contaminated food, are resistant to degradation by heat. Current food processing practices and conventional storage conditions do not completely
more » ... e aflatoxin contamination from the food supply chain. Long storage food products—such as peanuts, pistachio, nuts in general, and dried fruits—are susceptible to aflatoxins contamination. The type of plastic material can influence the concentration of aflatoxins during storage due to the permeability to gas and moisture exchange with the external milieu. Nuts in general and dried fruits are consumed in large quantities worldwide. Therefore, herein we investigated the effect of plastic material on the total aflatoxins and aflatoxin B1 content in 64 samples of nuts and dried fruits packed and stored in low-density polyethylene (LDPE), polypropylene (PP), polyethylene (PE), and polyethylene terephthalate (PET). The method consisted in a cleanup procedure using immunoaffinity columns coupled with RIDASCREEN FAST immunoenzymatic competitive assays based on the ELISA technique. Collected data were subjected to statistical analysis and multiple comparisons tests were applied. From the total analyzed samples, 14.06% exceeded the maximum admitted European levels for total aflatoxins. The highest concentrations of total aflatoxins were obtained from samples packed in LDPE, followed by PP, PE, and PET. Aflatoxin B1 was detected in all samples packed in LDPE, PP, and PE. Most of the samples packed in PET had concentrations <1 µg/kg. These results indicate that nuts in general packed and stored in LDPE are more prone to contamination with aflatoxins, while PET is more suitable for maintaining the quality and safety of these products.
doi:10.3390/microorganisms9010061 pmid:33379317 pmcid:PMC7823895 fatcat:vsaqhafgwzf3niiquqmmobokwe

Chitosan Functionalized Magnetic Nanoparticles to Provide Neural Regeneration and Recovery after Experimental Model Induced Peripheral Nerve Injury

Nadina Liana Pop, Alexandrina Nan, Andrada Elena Urda-Cimpean, Adrian Florea, Vlad Alexandru Toma, Remus Moldovan, Nicoleta Decea, Daniela Rodica Mitrea, Remus Orasan
2021 Biomolecules  
(1) Background: Peripheral nerve injuries have a great impact on a patient's quality of life and a generally poor outcome regarding functional recovery. Lately, studies have focused on different types of nanoparticles and various natural substances for the treatment of peripheral nerve injuries. This is the case of chitosan, a natural compound from the crustaceans' exoskeleton. The present study proposes to combine chitosan benefic properties to the nanoparticles' ability to transport different
more » ... substances to specific locations and evaluate the effects of magnetic nanoparticles functionalized with chitosan (CMNPs) on peripheral nerve injuries' rehabilitation by using an in vivo experimental model. (2) Methods: CMNPs treatment was administrated daily, orally, for 21 days to rats subjected to right sciatic nerve lesion and compared to the control group (no treatment) by analyzing the sciatic functional index, pain level, body weight, serum nerve growth factor levels and histology, TEM and EDX analysis at different times during the study. (3) Results: Animals treated with CMNPs had a statistically significant functional outcome compared to the control group regarding: sciatic functional index, pain-like behavior, total body weight, which were confirmed by the histological and TEM images. (4) Conclusions: The results of the study suggest that CMNPs appear to be a promising treatment method for peripheral nerve injuries.
doi:10.3390/biom11050676 pmid:33946445 fatcat:o67xobs2ojdotfspue7ruocij4
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