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Role of SimMan in teaching clinical skills to preclinical medical students

Meenakshi Swamy, Thomas C Bloomfield, Robert H Thomas, Harnaik Singh, Roger F Searle
2013 BMC Medical Education  
Simulation training has potential in developing clinical skills in pre-clinical medical students, but there is little evidence on its effectiveness. Methods: Twenty four first year graduate entry preclinical medical students participated in this crossover study. They were divided into two groups, one performed chest examination on each other and the other used SimMan. The groups then crossed over. A pretest, midtest and post-test was conducted in which the students answered the same
more » ... e with ten questions on knowledge, and confidence levels rated using a 5 point Likert scale. They were assessed formatively using the OSCE marking scheme. At the end of the session, 23 students completed a feedback questionnaire. Data was analyzed using one-way ANOVA and independent t-test. Results: When the two groups were compared, there was no significant difference in the pretest and the post-test scores on knowledge questions whereas the midtest scores increased significantly (P< 0.001) with the group using SimMan initially scoring higher. A significant increase in the test scores was seen between the pre-test and the mid-test for this group (P=0.009). There was a similar albeit non significant trend between the midtest and the post-test for the group using peer examination initially. Mean confidence ratings increased from the pretest to midtest and then further in the post-test for both groups. Their confidence ratings increased significantly in differentiating between normal and abnormal signs [Group starting with SimMan, between pretest and midtest (P= 0.01) and group starting with peer examination, between midtest and post-test (P=0.02)]. When the students' ability to perform examination on each other for both groups was compared, there was a significant increase in the scores of the group starting with SimMan (P=0.007). Conclusions: This pilot study demonstrated a significant improvement in the students' knowledge and competence to perform chest examination after simulation with an increase in the student's perceived levels of confidence. Feedback from the students was extremely positive. SimMan acts as a useful adjunct to teach clinical skills to preclinical medical students by providing a simulated safe environment and thus aids in bridging the gap between the preclinical and clinical years in medical undergraduate education.
doi:10.1186/1472-6920-13-20 pmid:23394435 pmcid:PMC3572432 fatcat:tom4etdu7zfi7e645pui3kv6nm

Generation of polarization entanglement via the quantum Zeno effect [article]

Ian C. Nodurft, Harry C. Shaw, Ryan T. Glasser, Brian T. Kirby, Thomas A. Searles
2022 arXiv   pre-print
and waveguide-absorber system b/B in (1) and ( 2 ) are now relabelled to c/C.  ...  ĈRE ĉL ) + λ( ĈRG ĉ † R + ĈEL ĉ † R + ĈLG ĉ † L + ĈER ĉ † L ). ( 15 ) Contrasting ( 14 ) and ( 15 ) with ( 1 ) and ( 2 ) respectively, waveguide b is the middle waveguide with no absorbers present  ... 
arXiv:2205.02315v2 fatcat:fuyphdffc5a3bcoxyauadtir6m

Polarization-selective modulation of supercavity resonances originating from bound states in the continuum

Chan Kyaw, Riad Yahiaoui, Joshua A. Burrow, Viet Tran, Kyron Keelen, Wesley Sims, Eddie C. Red, Willie S. Rockward, Mikkel A. Thomas, Andrew Sarangan, Imad Agha, Thomas A. Searles
2020 Communications Physics  
The quality (Q-) factors for (c) x-pol and (d) y-pol BIC resonances as a function of α are fitted with Q ∝ α −2 .  ...  The dimensions are length l of 250 μm, bracket width w of 35 μm and capacitive gap width c of 35 μm arranged in an array with 300 μm period.  ... 
doi:10.1038/s42005-020-00453-8 fatcat:g6oaqnjyfnfuje3wzf7xv5zfuq

IRE1α regulates macrophage polarization, PD-L1 expression, and tumor survival

Alyssa Batista, Jeffrey J. Rodvold, Su Xian, Stephen C. Searles, Alyssa Lew, Takao Iwawaki, Gonzalo Almanza, T. Cameron Waller, Jonathan Lin, Kristen Jepsen, Hannah Carter, Maurizio Zanetti (+1 others)
2020 PLoS Biology  
Rodvold, Su Xian, Stephen C. Searles, Alyssa Lew, Gonzalo Almanza, Kristen Jepsen.  ...  Dose-dependent 4μ8C-mediated inhibition of ERAI induction by TERS CM in B16.  ... 
doi:10.1371/journal.pbio.3000687 pmid:32520957 fatcat:rvepotjlf5dhhdmpd5kkxuhyqu

Polarization Selective Modulation of the Supercavity Resonance from Friedrich-Wintgen Bound States in the Continuum [article]

C. Kyaw, R. Yahiaoui, J. A. Burrow, V. Tran, K. Keelen, W. Sims, E. C. Red, W. S. Rockward, M. A. Thomas, A. Sarangan, I. Agha, T. A. Searles
2020 arXiv   pre-print
The dependence of the central rotational degree (θ c ) of the FW BIC on asymmetry parameter (α) can be fitted exponentially with the equation θ c = 8.9 + 79.3 exp (-0.013 α).  ...  Furthermore, a colormap for simulated amplitude as a function of incident polarization angle is presented in Fig. 3(c) .  ... 
arXiv:2001.05956v1 fatcat:s2namb3yevgcvbavkfsjadhwhu

Divergent evolutionary processes associated with colonization of offshore islands

Natália Martínková, Ross Barnett, Thomas Cucchi, Rahel Struchen, Marine Pascal, Michel Pascal, Martin C. Fischer, Thomas Higham, Selina Brace, Simon Y. W. Ho, Jean-Pierre Quéré, Paul O'Higgins (+5 others)
2013 Molecular Ecology  
D C : average distance between the observed and 1000 simulated summary statistics computed over the three Mainland Orkney populations for each continental population (c) to find the most likely source  ...  Similar stochastic processes can also explain microsatellite vari-ation among Scottish Island populations of common shrew (White & Searle 2007a) .  ... 
doi:10.1111/mec.12462 pmid:23998800 pmcid:PMC4159590 fatcat:b3vy4ls4pjdyblv6b74wsgasfu

Models of high velocity impacts into dust-covered ice: Application to Martian northern lowlands

A. Reufer, N. Thomas, W. Benz, S. Byrne, V. Bray, C. Dundas, M. Searls
2010 Planetary and Space Science  
For water ice this is the case above r 0 C 2 0 % 0:9 GPa (Mitani, 2003) .  ...  In the strong shock regime, where the stresses strongly exceed the term r 0 C 2 0 (r 0 : density, C 0 : speed of sound, both at zero stress), attenuation parametrized by a reaches the highest value.  ... 
doi:10.1016/j.pss.2010.04.008 fatcat:ul5jvm7l5fc4lhgpjvy5jbdaiq

Orbitofrontal Connectivity with Resting-State Networks Is Associated with Midbrain Dopamine D3 Receptor Availability

David M. Cole, Christian F. Beckmann, Graham E. Searle, Christophe Plisson, Andri C. Tziortzi, Thomas E. Nichols, Roger N. Gunn, Paul M. Matthews, Eugenii A. Rabiner, John D. Beaver
2011 Cerebral Cortex  
Here, we used a novel combination of [ 11 C]-(1)-PHNO positron emission tomography and resting-state functional magnetic resonance imaging in the same healthy individuals to investigate whether differences  ...  ; Searle et al. 2010 ).  ...  Recent findings have shown that [ 11 C]-(+)-PHNO can be used to quantify the in vivo availability of both D3R and D2R subtypes (Rabiner et al. 2009; Searle et al. 2010) . [ 11 C]-(+)-PHNO binding in the  ... 
doi:10.1093/cercor/bhr354 pmid:22186675 fatcat:td4sulnfenhdvlni4vwpn2cluq

Staggered Chromosomal Hybrid Zones in the House Mouse: Relevance to Reticulate Evolution and Speciation

İslam Gündüz, Christianne L. Pollock, Mabel D. Giménez, Daniel W. Förster, Thomas A. White, Maria A. Sans-Fuentes, Heidi C. Hauffe, Jacint Ventura, María José López-Fuster, Jeremy B. Searle
2010 Genes  
A new allele (c) arises within the hybrid zone and its high frequency causes staggering of the clines for the race-specific alleles.  ...  In the house mouse, there is considerable evidence of reduced fertility and even complete sterility in hybrids between chromosomal races, relating to their chromosomal differences, as reviewed in Searle  ... 
doi:10.3390/genes1020193 pmid:24710041 pmcid:PMC3954089 fatcat:vl3rhlsudvauthyrgbzeqsbgpy

Loss of phosphodiesterase 10A expression is associated with progression and severity in Parkinson's disease

Flavia Niccolini, Thomas Foltynie, Tiago Reis Marques, Nils Muhlert, Andri C. Tziortzi, Graham E. Searle, Sridhar Natesan, Shitij Kapur, Eugenii A. Rabiner, Roger N. Gunn, Paola Piccini, Marios Politis
2015 Brain  
(C) Higher bradykinesia subscore was correlated with lower 11 C-IMA107 BP ND in caudate (r = À0.58; P = 0.007), putamen (r = À0.53; P = 0.010) and globus pallidus (r = À0.69; P 5 0.001).  ...  Parametric images of 11 C-IMA107 binding potential relative to nondisplaceable binding (BP ND ) were generated from the dynamic 11 C-IMA107 scans using the simplified reference tissue model with the cerebellum  ...  We assessed whether clinically asymmetric limb motor features correspond to 11 C-IMA107 BP ND decreases, and we found no significant differences in 11 C-IMA107 BP ND between the most and less affected  ... 
doi:10.1093/brain/awv219 pmid:26210536 fatcat:mrw3zyqshvhonbgayisalvyws4

Quantifying the economic impact of soil constraints on Australian agriculture: A case-study of wheat

Thomas G. Orton, Thilak Mallawaarachchi, Matthew J. Pringle, Neal W. Menzies, Ram C. Dalal, Peter M. Kopittke, Ross Searle, Zvi Hochman, Yash P. Dang
2018 Land Degradation and Development  
c set to some defined optimum (i.e. non-limiting) value.  ...  ; Jeffrey et al., 2001) database hosted by the Queensland Government, and (v) soil data from soil profiles across Australia's cropping land, predominantly from the National Soil Site Collation (NSSC; Searle  ... 
doi:10.1002/ldr.3130 fatcat:6ubkyjchvbggfgu7ql2ic22z7i

Impacts of habitat fragmentation on genetic diversity in a tropical forest butterfly on Borneo

Suzan Benedick, Thomas A. White, Jeremy B. Searle, Keith C. Hamer, Nazirah Mustaffa, Chey Vun Khen, Maryati Mohamed, Menno Schilthuizen, Jane K. Hill
2007 Journal of Tropical Ecology  
Many areas of rain forest now exist as habitat fragments, and understanding the impacts of fragmentation is important for determining the viability of populations within forest remnants. We investigated impacts of forest fragmentation on genetic diversity in the butterfly Mycalesis orseis (Satyrinae) in Sabah (Malaysian Borneo). We investigated
doi:10.1017/s0266467407004543 fatcat:3vbox4iwpjabbb7ndebnn6oh24

Sarcolemma [chapter]

Gordon S. Lynch, David G. Harrison, Hanjoong Jo, Charles Searles, Philippe Connes, Christopher E. Kline, C. Castagna, Carsten Juel, David J. Bishop, Fin Biering-Sørensen, Wilhelm Bloch, Klara Brixius (+11 others)
2012 Encyclopedia of Exercise Medicine in Health and Disease  
Juel C, Lundby C, Sander M, Calbet JAL, van Hell G (2003) Human skeletal muscle and erythrocyte proteins involved in acid-base homeostasis: adaptation to chronic hypoxia.  ...  Castagna C, Impellizzeri FM, Chaouachi A, Bordon C, Manzi V (2011) Effect of training intensity distribution on aerobic fitness variables in elite soccer players: a case study.  ... 
doi:10.1007/978-3-540-29807-6_2992 fatcat:beeir3wm3vcgjb4xxk3udrnvmq

Dimerisation of the UBA Domain of p62 Inhibits Ubiquitin Binding and Regulates NF-κB Signalling

Jed Long, Thomas P. Garner, Maya J. Pandya, C. Jeremy Craven, Ping Chen, Barry Shaw, Michael P. Williamson, Robert Layfield, Mark S. Searle
2010 Journal of Molecular Biology  
Mutations within the gene encoding p62 are commonly found in patients with Paget's disease of bone and largely cluster within the C-terminal ubiquitin-associated (UBA) domain, impairing its ability to  ...  NMR analysis shows that the dimer interface partially occludes the Ub-binding surface, particularly at the C-terminus of helix 3, making UBA dimerisation and Ub-binding mutually exclusive processes.  ...  The Nand C-termini have been removed for clarity. (c) Structures in (b) rotated by 90°.  ... 
doi:10.1016/j.jmb.2009.11.032 pmid:19931284 fatcat:qk4pgrrhl5hljbji57ry5wl53i

Disrupted apical exocytosis of cargo vesicles causes enteropathy in FHL5 patients with Munc18-2 mutations

Georg F. Vogel, Jorik M. van Rijn, Iris M. Krainer, Andreas R. Janecke, Carsten Posovzsky, Marta Cohen, Claire Searle, Prevost Jantchou, Johanna C. Escher, Natalie Patey, Ernest Cutz, Thomas Müller (+3 others)
2017 JCI Insight  
(arrowheads in B and C).  ...  However, HS-Munc18_gR-d232 failed to revert the phenotype (Figure 4 , B and C).  ... 
doi:10.1172/jci.insight.94564 pmid:28724787 pmcid:PMC5518552 fatcat:dv6dlp6o4zddldqukulywcuj3m
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