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Thickness Mapping of Eleven Retinal Layers in Normal Eyes Using Spectral Domain Optical Coherence Tomography [article]

Raheleh Kafieh, Hossein Rabbani, Fedra Hajizadeh, Michael D. Abramoff, Milan Sonka
2013 arXiv   pre-print
This study was conducted to determine the thickness map of eleven retinal layers in normal subjects by spectral domain optical coherence tomography (SD-OCT) and evaluate their association with sex and  ...  Mean regional retinal thickness of 11 retinal layers were obtained by automatic three-dimensional diffusion-map-based method in 112 normal eyes of 76 Iranian subjects. Results.  ...  The advancement of spectral domain OCT (SD-OCT) over Standard time domain Optical Coherence Tomography (TD-OCT) provides higher speed of imaging; consequently, less eye motion artifact makes new systems  ... 
arXiv:1312.3199v1 fatcat:ofphlb4agnemxclsk7thyhfeg4

Effect of optic disc–fovea distance on the normative classifications of macular inner retinal layers as assessed with OCT in healthy subjects

Kunliang Qiu, Binyao Chen, Jianling Yang, Ce Zheng, Haoyu Chen, Mingzhi Zhang, Nomdo M Jansonius
2018 British Journal of Ophthalmology  
To determine the influence of the optic disc-fovea distance (DFD) on the normative classifications based on thickness measurements of macular inner retinal layers with spectral-domain optical coherence  ...  tomography (OCT) in healthy subjects.  ...  damage. 3 Spectral-domain optical coherence tomography (SD-OCT) enables in vivo measurements of macular inner retinal layers, including the retinal nerve fibre layer (RNFL) and the ganglion cell-inner  ... 
doi:10.1136/bjophthalmol-2018-312162 pmid:30100556 pmcid:PMC6582723 fatcat:tjxnwi24nfaa7jsx2z2f7vfvim

A comparison between amblyopic and fellow eyes in unilateral amblyopia using spectral-domain optical coherence tomography

Syunsuke Araki, Atsushi Miki, Tsutomu Yamashita, Katsutoshi Goto, Kazuko Haruishi, Yoshiaki Ieki, Junichi Kiryu
2014 Clinical Ophthalmology  
coherence tomography.  ...  A total of 21 patients with unilateral amblyopia (14 patients with anisometropic amblyopia, four patients with strabismic amblyopia, and three patients with both) were examined using spectral-domain optical  ...  Abbreviations: BCVA, best corrected visual acuity; cpRNFL, circumpapillary retinal nerve fiber layer; logMAR, logarithm of the minimal angle of resolution; SD-OCT, spectral domain optical coherence tomography  ... 
doi:10.2147/opth.s69501 pmid:25404852 pmcid:PMC4230232 fatcat:fybis7m6kracler5on4gdrrboq

Automated segmentation of outer retinal layers in macular OCT images of patients with retinitis pigmentosa

Qi Yang, Charles A. Reisman, Kinpui Chan, Rithambara Ramachandran, Ali Raza, Donald C. Hood
2011 Biomedical Optics Express  
To provide a tool for quantifying the effects of retinitis pigmentosa (RP) seen on spectral domain optical coherence tomography images, an automated layer segmentation algorithm was developed.  ...  This algorithm, based on dual-gradient information and a shortest path search strategy, delineates the inner limiting membrane and three outer retinal boundaries in optical coherence tomography images  ...  Introduction Optical coherence tomography (OCT) has emerged as an important noninvasive imaging modality in the field of ophthalmology, especially with the introduction of spectral domain OCT (SD-OCT)  ... 
doi:10.1364/boe.2.002493 pmid:21991543 pmcid:PMC3184859 fatcat:wfa7fooh6fh7hgsmnosrbfw4bi

Progression of Retinal Pigment Epithelial Atrophy in Antiangiogenic Therapy of Neovascular Age-Related Macular Degeneration

Christopher Schütze, Manuela Wedl, Bernhard Baumann, Michael Pircher, Christoph K. Hitzenberger, Ursula Schmidt-Erfurth
2015 American Journal of Ophthalmology  
coherence tomography (OCT).  ...  PURPOSE: To monitor retinal pigment epithelial (RPE) atrophy progression during antiangiogenic therapy of neovascular age-related macular degeneration (AMD) over 2 years using polarization-sensitive optical  ...  INTENSITY-BASED SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING: Spectralis SD OCT high-resolution macular raster scans, scans of the foveal region, and macular thickness maps were used in this study  ... 
doi:10.1016/j.ajo.2015.02.020 pmid:25769245 pmcid:PMC4430174 fatcat:3yn65lcgx5apjkncmfldywtsuq

Optical coherence tomography of the preterm eye: from retinopathy of prematurity to brain development

Cynthia Toth, Adam Rothman, Shwetha Mangalesh, Xi Chen
2016 Eye and Brain  
Optical coherence tomography has increased understanding of normal eye development and has identified several potential biomarkers of brain abnormalities and poorer neurodevelopment.  ...  We describe optical coherence tomography as a powerful imaging modality that has recently been adapted to the infant population and provides noninvasive, high-resolution, cross-sectional imaging of the  ...  She also has unlicensed patents pending in OCT imaging and analysis. No authors have a proprietary interest in the current study. Disclosure The authors report no conflicts of interest in this work.  ... 
doi:10.2147/eb.s97660 pmid:28539807 pmcid:PMC5398750 fatcat:y7w2iv7drfdj3hguqbrfvtvimy

Macular Ganglion Cell Inner Plexiform Layer Thinning In Patients With Visual Field Defect That Respects The Vertical Meridian

Hye-Young Shin, Chan Kee Park
2015 Zenodo  
To compare the thinning patterns of the ganglion cell-inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (pRNFL) as measured using Cirrus high-definition optical coherence tomography  ...  The thicknesses of the macular GCIPL and pRNFL were measured using Cirrus HD-OCT.  ...  and take responsibility for the integrity of the data and the accuracy of the data analysis as well as the decision to submit for publication.  ... 
doi:10.5281/zenodo.1109831 fatcat:6kummd7yp5crfjaebzbza7u3rm

Thickness Mapping of Eleven Retinal Layers Segmented Using the Diffusion Maps Method in Normal Eyes

Raheleh Kafieh, Hossein Rabbani, Fedra Hajizadeh, Michael D. Abramoff, Milan Sonka
2015 Journal of Ophthalmology  
This study was conducted to determine the thickness map of eleven retinal layers in normal subjects by spectral domain optical coherence tomography (SD-OCT) and evaluate their association with sex and  ...  Mean regional retinal thickness of 11 retinal layers was obtained by automatic three-dimensional diffusion map based method in 112 normal eyes of 76 Iranian subjects.  ...  The sponsor or funding organization had no role in the design or conduct of this research.  ... 
doi:10.1155/2015/259123 pmid:25960888 pmcid:PMC4417595 fatcat:du37mcplovf5pmpuhfndal6r6m

Diagnostic accuracy of total macular and ganglion cell layer thickness in differentiating different stages of glaucoma: an SD-OCT study

Wen Yee Lee, Norlina Mohd Ramli, Amir Samsudin, Mimiwati binti Zahari, Azida Juana binti Wan Ab Kadir, Ahmad Mt Saad
2021 Malaysian journal of ophthalmology  
Purpose: To determine the diagnostic accuracy of mean macular retinal thickness (mRT) and macular ganglion cell layer (mGCL) thickness measured by Spectralis spectral-domain optical coherence tomography  ...  (SD-OCT) posterior pole thickness map (PPTM) in differentiating between normal and glaucoma eyes of different severity.Study design: Cross-sectional study.Methods: All subjects were divided into normal  ...  Diagnostic accuracy of mRT and mGCL in glaucoma staging  ... 
doi:10.35119/myjo.v3i3.221 fatcat:mrmgp2u3knduhmlzwnligkcw2e

Retinal Ganglion Cell Layer Thinning Within One Month of Presentation for Non-Arteritic Anterior Ischemic Optic Neuropathy

Mark J. Kupersmith, Mona K. Garvin, Jui-Kai Wang, Mary Durbin, Randy Kardon
2016 Investigative Ophthalmology and Visual Science  
Retinal ganglion cell layer thinning within one month of presentation for non-arteritic anterior ischemic optic neuropathy.  ...  Optical coherence tomography reveals retinal ganglion cell layer (GCL) and retinal nerve fiber layer (RNFL) thinning in chronic optic nerve injury.  ...  We prospectively studied 29 acute NAION eyes with standard automated perimetry and spectral domain (SD) optical coherence tomography for 6 months.  ... 
doi:10.1167/iovs.15-18736 pmid:27388052 pmcid:PMC5996873 fatcat:uqlc3jjhvbhnfcu4rx3b6e4fvm

Central Macular Thickness in a Healthy Mexican Population Using Huvitz Optical Coherence Tomography

Renata García-Franco, Dalia Méndez-Marín, Marlon García-Roa, Paulina Ramirez-Neria, Diego Valera-Cornejo, Van Charles Lansingh
2020 Clinical Ophthalmology  
To determine normal macular thickness values in a healthy Mexican population and its variation by age and gender using Huvitz spectral-domain optical coherence tomography (HOCT-1F).  ...  Normal macular thickness values using the Huvitz OCT in a Mexican healthy population aged from 18-70 years were thinner in the foveal macular region than values reported in other populations.  ...  Disclosure The authors have no financial disclosures nor conflict of interest.  ... 
doi:10.2147/opth.s272431 pmid:33235432 pmcid:PMC7680185 fatcat:hsli4oojfzc3ngyskdvjh3lgda

Evaluation of Significance Maps and the Analysis of the Longitudinal Time Course of the Macular Ganglion Cell Complex Thicknesses in Acquired Occipital Homonymous Hemianopia Using Spectral-domain Optical Coherence Tomography

Tsutomu Yamashita, Atsushi Miki, Katsutoshi Goto, Syunsuke Araki, Go Takizawa, Yoshiaki Ieki, Junichi Kiryu, Akio Tabuchi, Yasuyuki Iguchi, Kazumi Kimura, Yoshiki Yagita
2019 Neuro-ophthalmology (Aeolus Press. 1980)  
hemianopia due to posterior cerebral artery (PCA) territory stroke using spectral-domain optical coherence tomography.  ...  The present study was performed to evaluate the ganglion cell complex (GCC) thickness as well as the significance map and analyse the time course of the change in GCC thickness in patients with homonymous  ...  Funding The Japan Society for the Promotion of Science (JPSP) provided financial support in the form of KAKENHI Grants-in-Aid [Grant Number 17K11497].  ... 
doi:10.1080/01658107.2019.1686764 pmid:33012909 pmcid:PMC7518317 fatcat:mgiazklrg5brjneyjv4r6yhclu

Reproducibility of Retinal Thickness Measurements across Spectral-Domain Optical Coherence Tomography Devices using Iowa Reference Algorithm [article]

Adnan Rashid, Sebastian M. Waldstein, Bianca S. Gerendas, Hrvoje Bogunovic, Andreas Wahle, Kyungmoo Lee, Kai Wang, Christian Simader, Michael D. Abramoff, Ursula Schmidt-Erfurth, Milan Sonka
2016 arXiv   pre-print
PURPOSE: Establishing and obtaining consistent quantitative indices of retinal thickness from a variety of clinically used Spectral-Domain Optical Coherence Tomography scanners.  ...  DESIGN: Retinal images from five Spectral-Domain Optical Coherence Tomography scanners were used to determine total retinal thickness with scanner-specific correction factors establishing consistency of  ...  Acknowledgments This work was partially supported by The Christian Doppler Society OPTIMA project; NIH grants R01 EY019112, R01 EY018853 and R01 EB004640; the Department of Veterans Affairs; the Marlene  ... 
arXiv:1612.06442v1 fatcat:t5zesclb75aghprgdib5u7yy74

Diagnostic Specificities of Retinal Nerve Fiber Layer, Optic Nerve Head, and Macular Ganglion Cell-Inner Plexiform Layer Measurements in Myopic Eyes

Ahmad A. Aref, Fouad E. Sayyad, Jean-Claude Mwanza, William J. Feuer, Donald L. Budenz
2014 Journal of glaucoma  
The study eye then underwent optic nerve and macular scanning using spectral-domain optical coherence tomography (OCT) instrumentation to determine RNFL thickness, GC-IPL thickness, and ONH measurements  ...  Purpose-To evaluate and compare the diagnostic specificities of peripapillary retinal nerve fiber layer (RNFL) thickness, macular ganglion cell-inner plexiform layer (GC-IPL) thickness, and optic nerve  ...  INTRODUCTION Glaucoma is an optic neuropathy characterized by the death of retinal ganglion cells and their accompanying axons. 1 Optical coherence tomography (OCT) aids in the diagnosis and management  ... 
doi:10.1097/ijg.0b013e31827b155b pmid:23221911 pmcid:PMC3986352 fatcat:2nckmmnndbbxlngh7r6j2wgo5e

OCT-Angiography reveals reduced vessel density in the deep retinal plexus of CADASIL patients

Pieter Nelis, Ilka Kleffner, Matthias C. Burg, Christoph R. Clemens, Maged Alnawaiseh, Jeremias Motte, Martin Marziniak, Nicole Eter, Florian Alten
2018 Scientific Reports  
In 2014, our group used high-resolution retinal imaging including spectral-domain optical coherence tomography (SD-OCT) in CADASIL patients and showed significantly increased wall thicknesses as well as  ...  Optical coherence tomography angiography (OCT-A) represents the most recent tool in ophthalmic imaging.  ...  Acknowledgements We acknowledge support by Open Access Publication Fund of University of Muenster.  ... 
doi:10.1038/s41598-018-26475-5 pmid:29802397 pmcid:PMC5970147 fatcat:qlbgcphkpreexlfejfejua3mj4
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