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On the design and implementation of a RISC processor extension for the KASUMI encryption algorithm

Tomas Balderas-Contreras, Rene Cumplido, Claudia Feregrino-Uribe
2008 Computers & electrical engineering  
KASUMI has the following features: it performs 8 rounds of ciphering, the input plaintext is the input to the first round, ciphertext is the last round's output, K is used to generate a set of round keys  ...  Thus, the proposed architecture offers a good alternative for implementing the KASUMI algorithm.  ...  The proposed approach scheme is a good alternative when the security functions must coexist with other operations as the functional unit for encryption does not interfere with a number of other custom  ... 
doi:10.1016/j.compeleceng.2007.11.003 fatcat:4hvrlqdwujdkheh5p7v63ii6de

Reducing the time required by KASUMI to generate output by modifying the FL and FI functions

Raja Muthalagu, Subeen Jain
2018 Iran Journal of Computer Science  
Also, we proposed a modification in FL functions: FL(a) and FL(b) of the existing KASUMI block cipher.  ...  This work proposed the modifications in existing KASUMI block cipher, which can reduce time delay for generating 64-bit encrypted data.  ...  Another study done by a group of researchers came up with "related-key rectangle" attack on full round KASUMI, but this type of attack was successful theoretically only.  ... 
doi:10.1007/s42044-018-0017-2 fatcat:s677n6ig7zaorftsbldwkmlk44

Leveraging the Multiprocessing Capabilities of Modern Network Processors for Cryptographic Acceleration

G. Gaubatz, B. Sunar
2005 Fourth IEEE International Symposium on Network Computing and Applications  
In this paper we present a highly scalable bit sliced implementation of the Kasumi block cipher for the Intel IXP 28xx family of network processors.  ...  The Kasumi block cipher provides integrity and confidentiality services for 3G wireless networks, but it also forms a bottleneck due to its computational overhead.  ...  In each round, alternating between the left and right halves of the state, one half enters the outer round function FO() for processing.  ... 
doi:10.1109/nca.2005.28 dblp:conf/nca/GaubatzS05 fatcat:nkggvntgurcy3ila2pr5mbkbla

RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia

Vasily V. Grinev, Farnaz Barneh, Ilya M. Ilyushonak, Sirintra Nakjang, Job Smink, Anita van Oort, Richard Clough, Michael Seyani, Hesta McNeill, Mojgan Reza, Natalia Martinez-Soria, Salam A. Assi (+3 others)
2021 Nature Communications  
We also show that RUNX1/RUNX1T1-mediated differential splicing affects several functional groups of genes and produces proteins with unique conserved domain structures.  ...  The second mechanism generates alternative transcripts with new junctions between internal cassettes and constitutive exons.  ...  Code availability All R codes of this study were deposited at GitHub software project TranscriptomicFeatures ( 70  ... 
doi:10.1038/s41467-020-20848-z pmid:33483506 fatcat:i5qtrjffybdprmj4gkl2wwkahu

Survey and benchmark of block ciphers for wireless sensor networks

Yee Wei Law, Jeroen Doumen, Pieter Hartel
2006 ACM transactions on sensor networks  
In terms of operation mode, we recommend Output Feedback Mode for pairwise links but Cipher Block Chaining for group communications.  ...  For evaluating and assessing these candidates, we not only consider the security properties but also the storage-and energy-efficiency of the candidates.  ...  ACKNOWLEDGMENTS The authors would like to thank Adrian Perrig and the anonymous reviewers for their inspiring comments, which have vastly improved this article.  ... 
doi:10.1145/1138127.1138130 fatcat:jlm77sv6rvdi3jzgmbnumg6pua

RUNX1/RUNX1T1 controls alternative splicing in the t(8;21)-positive acute myeloid leukemia cells [article]

Vasily Grinev, Ilia Ilyushonak, Richard Clough, Sirintra Nakjang, Job Smink, Natalia Martinez-Soria, Tatsiana Ramanouskaya, Constanze Bonifer, Olaf Heidenreich
2019 bioRxiv   pre-print
We also show that RUNX1/RUNX1T1-mediated differential splicing affects several functional groups of genes and produces proteins with unique conserved domain structures.  ...  The second mechanism generates alternative transcripts with new junctions between internal cassettes and constitutive exons.  ...  Research in the V.G. laboratory was supported in part by the Ministry of Education of the Republic of Belarus, grant #3.08.3.  ... 
doi:10.1101/628040 fatcat:7ntkc5s67bgozltpc2hht3khfa

A UML 2.0 Profile to Model Block Cipher Algorithms [chapter]

Tomás Balderas-Contreras, Gustavo Rodriguez-Gomez, René Cumplido
2010 Lecture Notes in Computer Science  
This automated process should alleviate design complexity and increase the productivity of the developer during experimentation with different design alternatives.  ...  To achieve higher performance, the security algorithms are usually implemented as dedicated hardware functional units attached to the main processing units of the embedded communication system.  ...  This dual-input FI function block is used by the simplified version of the FO function twice per round; see Figure 3 (b).  ... 
doi:10.1007/978-3-642-13595-8_4 fatcat:7nz3menyavcfdaelyedo6vt34a

Transfection of Kasumi-1 cells with a new type of polymer carriers loaded with miR-155 and antago-miR-155

O V Klimenko, M I Shtilman
2013 Cancer Gene Therapy  
In our experiments, we used a new type of polymer carriers to monitor the effects of miR-155 and antago-miR-155 on the morphology and genetics of Kasumi-1 cells.  ...  Previous studies have demonstrated functional roles for microRNAs (miRNAs) in various aspects of normal and malignant hematopoiesis, including lineage commitment, differentiation, apoptosis and maturation  ...  Alternatively, in both the control group and the group transfected with miR-155, no visual changes were observed in the Kasumi-1 cell morphology.  ... 
doi:10.1038/cgt.2013.11 pmid:23538486 fatcat:q2jaygsy4fgq3od6lydpkdu3su

KAMAR: A Lightweight Feistel Block Cipher Using Cellular Automata

Jegadish Kumar Kailairajan Jeyaprakash, Joseph Gladwin Seka, Kamaraj Villayutham
2016 Circuits and Systems  
The primary factors considered in the design and deployment of WSN are low power consumption, high speed and memory requirements. Security is indeed a major concern, in any communication system.  ...  The proposed approach supports both software and hardware implementation and provides better performance compared to other existing algorithms in terms of number of slices, throughput and other hardware  ...  In designing the hardware, they focused on optimizing the implementation of FO/FI functions that are the major components of KASUMI.  ... 
doi:10.4236/cs.2016.74021 fatcat:m4ogy243krgh3oppo46ruz67wy

A note on an infeasible linearization of some block ciphers

Riccardo Aragona, Anna Rimoldi, Massimiliano Sala
2018 Journal of Discrete Mathematical Sciences and Cryptography  
Even more so, if its round functions can be seen as linear maps on a small vector space. We show that this cannot happen for the AES.  ...  More precisely, we prove that if the AES round transformations can be embedded into a linear cipher acting on a vector space, then this space is huge-dimensional and so this embedding is infeasible in  ...  Acknowledgment The authors would like to thank Rüdiger Sparr and Ralph Wernsdorf for their helpful suggestions and interesting comments.  ... 
doi:10.1080/09720529.2016.1197598 fatcat:vq3ehkuxrncstnujigrr66jkna

A novel exon in AML1-ETO negatively influences the clonogenic potential of the t(8;21) in acute myeloid leukemia

D Mannari, D Gascoyne, J Dunne, T Chaplin, B Young
2010 Leukemia  
To analyze the role of the NHR1 domain in AML1-ETOinduced leukemogenesis the AML1-ETO 6a transcript was used for further functional assessment.  ...  In this translocation the AML1 (RUNX1) gene coding for a DNA-binding domain, is fused to most of the ETO (RUNX1T1) gene, which encodes four nervy homology regions (NHRs) that function as repressors of  ...  Conflict of interest The authors declare no conflict of interest.  ... 
doi:10.1038/leu.2009.288 pmid:20111069 fatcat:v5aofbl2dzbexcfte6j4ifjiv4

A Novel Application of Furazolidone: Anti-Leukemic Activity in Acute Myeloid Leukemia

Xueqing Jiang, Lin Sun, Jihui Julia Qiu, Xiujing Sun, Sen Li, Xiyin Wang, Chi Wai Eric So, Shuo Dong, Alfons Navarro
2013 PLoS ONE  
We investigated the anti-leukemic activity of FZD in a series of AML cells. FZD displayed potent antiproliferative properties at submicromolar concentrations and induced apoptosis in AML cell lines.  ...  Furazolidone has been used in the treatment of certain bacterial and protozoan infections in human and animals for more than sixty years.  ...  Michele Redell (Division of Pediatric Hematology/ Oncology, Baylor College of Medicine) for critical reading of the manuscript.  ... 
doi:10.1371/journal.pone.0072335 pmid:23951311 pmcid:PMC3739762 fatcat:fz46svkl7jhsfgbixew7ifzsb4

Two Receptors, Two Isoforms, Two Cancers: Comprehensive Analysis of KIT and TrkA Expression in Neuroblastoma and Acute Myeloid Leukemia

Timofey D. Lebedev, Elmira R. Vagapova, Vladimir I. Popenko, Olga G. Leonova, Pavel V. Spirin, Vladimir S. Prassolov
2019 Frontiers in Oncology  
Though expression of these receptors is found in both tumors, little is known about KIT function in NB and TrkA in AML.  ...  Thus, we have provided a comprehensive characterization of TrkA and KIT expression along with the oncogenic signatures of these genes across two pediatric tumors.  ...  ACKNOWLEDGMENTS The authors wish to thank Ioanna Triviai and Carol Stocking from UKE Hamburg for kindly providing the cell lines used in this study.  ... 
doi:10.3389/fonc.2019.01046 pmid:31681584 pmcid:PMC6813278 fatcat:p4mdfby6d5hbnj2vtvhlsgedlq

Core binding factor leukemia hijacks T-cell prone PU.1 antisense promoter [article]

Emiel van der Kouwe, Gerwin Heller, Akos Czibere, Lucio H Castilla, Ruud Delwel, Annalisa Di Ruscio, Alexander K Ebralidze, Maurizio Forte, Lukas Kazianka, Christoph Kornauth, Trang Le, Karin Lind (+14 others)
2020 biorxiv/medrxiv   pre-print
Our results identify the first example of a sense/antisense promoter competition as a crucial functional switch for gene expression perturbation by oncogenes.  ...  Here we demonstrate that the down-regulation of PU.1 mRNA is a dynamic process involving an alternative promoter in intron 3 that is induced by RUNX transcription factors driving noncoding antisense transcription  ...  Ligated RNA was purified by a second round of Streptavidin beads enrichment and ligated with 5'-VRA RNA adaptor (5'-CCUUGGCACCCGAGAAUUCCA-3'). Ligated RNA was purified by a third round of .  ... 
doi:10.1101/2020.05.29.120857 fatcat:w3gsnev5rba25esnc2pmsf2rdm

miR-9 is a tumor suppressor in pediatric AML with t(8;21)

S Emmrich, J E Katsman-Kuipers, K Henke, M E Khatib, R Jammal, F Engeland, F Dasci, C M Zwaan, M L den Boer, L Verboon, J Stary, A Baruchel (+7 others)
2013 Leukemia  
The tumor-suppressive functions of miR-9 were specifically restricted to AML cell lines and primary leukemic blasts with t(8;21).  ...  On the other hand, these functions were not evident in AML blasts from patients with MLL rearrangements.  ...  JHK is a fellow of the Emmy Noether-Programme from the German Research Foundation (DFG; KL-2374/2-1).  ... 
doi:10.1038/leu.2013.357 pmid:24270738 fatcat:ie4sb4hrubb4hbukuliv7ilnwy
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