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The mouse genome database (MGD): new features facilitating a model system

J. T. Eppig, J. A. Blake, C. J. Bult, J. A. Kadin, J. E. Richardson
2007 Nucleic Acids Research  
The mouse genome database (MGD, http://www. informatics.jax.org/), the international community database for mouse, provides access to extensive integrated data on the genetics, genomics and biology of  ...  Thus, MGD's primary goals are to facilitate the use of mouse models for studying human disease and enable the development of translational research hypotheses based on comparative genotype, phenotype and  ...  ACKNOWLEDGEMENTS The Mouse Genome Database is supported by NIH/ NHGRI grant HG000330. Funding to pay the Open Access publication charges for this article was provided by The Mouse Genome Database.  ... 
doi:10.1093/nar/gkl940 pmid:17135206 pmcid:PMC1751527 fatcat:7k2or5spprcaxgacqxy6ju3bam

The Mouse Genome Database (MGD): updates and enhancements

J. A. Blake
2006 Nucleic Acids Research  
The Mouse Genome Database (MGD) integrates genetic and genomic data for the mouse in order to facilitate the use of the mouse as a model system for understanding human biology and disease processes.  ...  A core component of the MGD effort is the acquisition and integration of genomic, genetic, functional and phenotypic information about mouse genes and gene products.  ...  ACKNOWLEDGEMENTS The Mouse Genome Database is supported by NIH/ NHGRI grant HG00330. Funding to pay the Open Access publication charges for this article was provided by NHGRI P41-00330.  ... 
doi:10.1093/nar/gkj085 pmid:16381933 pmcid:PMC1347448 fatcat:xls3y2e44nevzpfc3bul6tyohy

The Mouse Genome Database (MGD): integrating biology with the genome

C. J. Bult
2004 Nucleic Acids Research  
The Mouse Genome Database (MGD) is one component of the Mouse Genome Informatics (MGI) system (http://www.informatics.jax.org), a community database resource for the laboratory mouse.  ...  MGD strives to provide a comprehensive knowledgebase about the mouse with experiments and data annotated from both literature and online sources.  ...  ACKNOWLEDGEMENTS MGD is supported by NIH/NHGRI grant HG00330.  ... 
doi:10.1093/nar/gkh125 pmid:14681461 pmcid:PMC308859 fatcat:uprwazyvfndahp6bojvp5rxqo4

Mouse Genome Database (MGD)-2018: knowledgebase for the laboratory mouse

Cynthia L Smith, Judith A Blake, James A Kadin, Joel E Richardson, Carol J Bult
2017 Nucleic Acids Research  
The Mouse Genome Database (MGD; http://www. informatics.jax.org) is the key community mouse database which supports basic, translational and computational research by providing integrated data on the genetics  ...  , genomics, and biology of the laboratory mouse.  ...  ACKNOWLEDGEMENTS We are grateful to our collaborators at Disease Ontology (DO) and Rat Genome Database (RGD) for providing updated disease ontology files and help with revisions and additions to the ontology  ... 
doi:10.1093/nar/gkx1006 pmid:29092072 pmcid:PMC5753350 fatcat:vvlq4zpe4jac7ik25sh26qrulq

The Mouse Genome Database (MGD): mouse biology and model systems

C. J. Bult, J. T. Eppig, J. A. Kadin, J. E. Richardson, J. A. Blake
2007 Nucleic Acids Research  
The Mouse Genome Database, (MGD, http:// www.informatics.jax.org/), integrates genetic, genomic and phenotypic information about the laboratory mouse, a primary animal model for studying human biology  ...  Recent improvements in MGD described here include the association of gene trap data with mouse genes and a new batch query capability for customized data access and retrieval.  ...  ACKNOWLEDGEMENTS The Mouse Genome Database is supported by NIH/ NHGRI grant HG000330. Funding to pay the Open Access publication charges for this article was provided by HG000330.  ... 
doi:10.1093/nar/gkm961 pmid:18158299 pmcid:PMC2238849 fatcat:pmebitz5ura4pmusobr7cfxbuy

The Mouse Genome Database (MGD): integration nexus for the laboratory mouse

J. A. Blake
2001 Nucleic Acids Research  
The Mouse Genome Database (MGD) is the community database resource for the laboratory mouse, a key model organism for interpreting the human genome and for understanding human biology and disease (http  ...  The integration and standardization of these data sets facilitates the transition between mouse DNA sequence, gene and phenotype annotations.  ...  ACKNOWLEDGEMENTS The Mouse Genome Database is supported by NIH grant HG00330. The MouseBLAST is supported by NIH:HG01559 and DOE:DE-FG02-99ER62850.  ... 
doi:10.1093/nar/29.1.91 pmid:11125058 pmcid:PMC29788 fatcat:tehxcnxurzaltlsmbtsbgkdfzq

The Mouse Genome Database (MGD): genetic and genomic information about the laboratory mouse

J. A. Blake, J. E. Richardson, M. T. Davisson, J. T. Eppig
1999 Nucleic Acids Research  
The Mouse Genome Database (MGD) focuses on the integration of mapping, homology, polymorphism and molecular data about the laboratory mouse.  ...  MGD is accessible at http://www.informatics.jax.org + The Mouse Genome Database Group:  ...  A new feature is the development of procedures for the submission of mouse mutant phenotype descriptions for characterized remutations of known genes.  ... 
doi:10.1093/nar/27.1.95 pmid:9847150 pmcid:PMC148105 fatcat:cdtowpch3rfpvlfa2qkirwhftm

Mouse Genome Database (MGD)-2017: community knowledge resource for the laboratory mouse

Judith A. Blake, Janan T. Eppig, James A. Kadin, Joel E. Richardson, Cynthia L. Smith, Carol J. Bult
2016 Nucleic Acids Research  
The Mouse Genome Database (MGD: http://www. informatics.jax.org) is the primary community data resource for the laboratory mouse.  ...  It provides a highly integrated and highly curated system offering a comprehensive view of current knowledge about mouse genes, genetic markers and genomic features as well as the associations of those  ...  ACKNOWLEDGEMENTS The authors thank David Shaw for his contributions and leadership in providing User Support services to the community of scientists who use MGD and all MGI data resources.  ... 
doi:10.1093/nar/gkw1040 pmid:27899570 pmcid:PMC5210536 fatcat:t7apqsxrl5h7zbjn4bo47zejhu

The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics

J. A. Blake, C. J. Bult, J. A. Kadin, J. E. Richardson, J. T. Eppig
2010 Nucleic Acids Research  
MGD includes a complete catalog of mouse genes and genome features with integrated access to genetic, genomic and phenotypic information, all serving to further the use of the mouse as a model system for  ...  The Mouse Genome Database (MGD) is the community model organism database for the laboratory mouse and the authoritative source for phenotype and functional annotations of mouse genes.  ...  Figure 1 . 1 New classification terms for MGD markers and genome features. The definitions for the terms are displayed when a user 'mouses over' a term.  ... 
doi:10.1093/nar/gkq1008 pmid:21051359 pmcid:PMC3013640 fatcat:lvzlsqzkuzg2nhthgtlm7f4mdm

The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease

Janan T. Eppig, Judith A. Blake, Carol J. Bult, James A. Kadin, Joel E. Richardson
2014 Nucleic Acids Research  
To facilitate use of mouse as a model in translational studies, MGD maintains a core of high-quality curated data and integrates experimentally and computationally generated data sets.  ...  The Mouse Genome Database (MGD, http://www. informatics.jax.org) serves the international biomedical research community as the central resource for integrated genomic, genetic and biological data on the  ...  Genome feature-genome feature relationships MGD has developed new infrastructure to support genome feature relationships.  ... 
doi:10.1093/nar/gku967 pmid:25348401 pmcid:PMC4384027 fatcat:vm3jknia2baepaxu23v6wytnaq

Mouse Genome Database (MGD): Knowledgebase for mouse–human comparative biology

Judith A Blake, Richard Baldarelli, James A Kadin, Joel E Richardson, Cynthia L Smith, Carol J Bult, Anna V Anagnostopoulos, Jon S Beal, Susan M Bello, Olin Blodgett, Nancy E Butler, Jeffry Campbell (+26 others)
2020 Nucleic Acids Research  
The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the community model organism knowledgebase for the laboratory mouse, a widely used animal model for comparative studies of the genetic  ...  MGD is the authoritative source for biological reference data related to mouse genes, gene functions, phenotypes and mouse models of human disease.  ...  MOUSE GENOME DATABASE GROUP ACKNOWLEDGEMENTS We thank the members of the MGD Scientific Advisory Board and members of our user community for their feedback and suggestions on the enhancements and new  ... 
doi:10.1093/nar/gkaa1083 pmid:33231642 fatcat:wlxmguufevcnvjsffgxlqxhg7e

The Mouse Genome Database genotypes::phenotypes

J. A. Blake, C. J. Bult, J. T. Eppig, J. A. Kadin, J. E. Richardson
2009 Nucleic Acids Research  
The Mouse Genome Database (MGD, http://www. informatics.jax.org/), integrates genetic, genomic and phenotypic information about the laboratory mouse, a primary animal model for studying human biology and  ...  Recent improvements in MGD described here include the unified mouse gene catalog for NCBI Build 37 of the reference genome assembly, and improved representation of mouse mutants and phenotypes.  ...  MGD facilitates translational biomedical research via a comprehensive database resource integrated with bioontological semantic standards that enhances the use of the laboratory mouse as a model animal  ... 
doi:10.1093/nar/gkn886 pmid:18981050 pmcid:PMC2686566 fatcat:2ipclifxdnbljet6f65fu4i52y

Orthology for comparative genomics in the mouse genome database

Mary E. Dolan, Richard M. Baldarelli, Susan M. Bello, Li Ni, Monica S. McAndrews, Carol J. Bult, James A. Kadin, Joel E. Richardson, Martin Ringwald, Janan T. Eppig, Judith A. Blake
2015 Mammalian Genome  
The mouse genome database (MGD) is the model organism database component of the mouse genome informatics system at The Jackson Laboratory.  ...  Since its beginnings, MGD has included comparative genomics data with a particular focus on humanmouse orthology, an essential component of the use of mouse as a model organism.  ...  Acknowledgments This work is funded through NIH grants HG000330 to MGD, HG002273 to the Gene Ontology Consortium, and HD062499 to GXD.  ... 
doi:10.1007/s00335-015-9588-5 pmid:26223881 pmcid:PMC4534493 fatcat:gsj5nwfyj5b4jkwsku72xkysve

The Mouse Genome Database: enhancements and updates

Carol J. Bult, James A. Kadin, Joel E. Richardson, Judith A. Blake, Janan T Eppig
2009 Nucleic Acids Research  
The Mouse Genome Database (MGD) is a major component of the Mouse Genome Informatics (MGI, http://www.informatics.jax.org/) database resource and serves as the primary community model organism database  ...  MGD is the authoritative source for mouse gene, allele and strain nomenclature and for phenotype and functional annotations of mouse genes.  ...  MGD is a central component of the Mouse Genome Informatics (MGI) database resource (http://www.informatics.jax.org), the community model organism database for the laboratory mouse.  ... 
doi:10.1093/nar/gkp880 pmid:19864252 pmcid:PMC2808942 fatcat:4azrklowubgqxfc7fogb5644ei

The Mouse Genome Database: Genotypes, Phenotypes, and Models of Human Disease

C. J. Bult, J. T. Eppig, J. A. Blake, J. A. Kadin, J. E. Richardson
2012 Nucleic Acids Research  
The Mouse Genome Database (MGD; http://www.in formatics.jax.org), the community model organism database for the laboratory mouse, is designed to facilitate the use of the laboratory mouse as a model system  ...  To achieve this goal, MGD integrates genetic and genomic data related to the functional and phenotypic characterization of mouse genes and alleles and serves as a comprehensive catalog for mouse models  ...  MGD is the highly curated, community model organism database for the laboratory mouse providing web and programmatic access to a complete catalog of mouse genes and genome features integrated with functional  ... 
doi:10.1093/nar/gks1115 pmid:23175610 pmcid:PMC3531104 fatcat:wy46bll54nh2fjml37337yqva4
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