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Transcranial brain stimulation: potential and limitations

W. Paulus
2014 e-Neuroforum  
They encompass the range from tran­scranial direct current stimulation (tDCS) to high frequency alternating current stimulation (tACS) in the kilohertz range.  ...  A differentiation is made between short-lived interference with ongoing brain activity, and plastic changes that persist for a longer period beyond the end of the stimulation.Weaker electric fields in  ...  Weaker electric fields in the 1 mA range can be applied painlessly through the skull.  ... 
doi:10.1515/s13295-014-0056-6 fatcat:5q7pw7nuqbbefdztturoodaayi

Clinical Applications of Transcranial Magnetic Stimulation in Pediatric Neurology

Shalini Narayana, Andrew C. Papanicolaou, Amy McGregor, Frederick A. Boop, James W. Wheless
2014 Journal of Child Neurology  
The article describes and provides examples of the current clinical applications of transcranial magnetic stimulation in children as an aid in the diagnosis and treatment of neuropsychiatric disorders  ...  Improvements in the spatial accuracy of transcranial magnetic stimulation are described in the context of image-guided transcranial magnetic stimulation.  ...  Author Contributions SN conceived the study, performed literature search, acquired and processed transcranial magnetic stimulation data, assimilated and interpreted all the data, and drafted this manuscript  ... 
doi:10.1177/0883073814553274 pmid:25342309 fatcat:jgllqcwwv5cababzqlz5yujury

Noninvasive Brain Stimulation in the Study of the Human Visual System

Mark A. Halko, Mark C. Eldaief, Alvaro Pascual-Leone
2013 Journal of glaucoma  
There are currently two techniques to manipulate brain function non-invasively: transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS).  ...  When fMRI is used as an outcome measure, it is possible to identify the specificity of tDCS-modulated plasticity in a visual rehabilitation protocol.  ...  The change in magnetic field induces a secondary electrical current in nearby conductors. In case of TMS, the secondary conductor is the cerebral cortex.  ... 
doi:10.1097/ijg.0b013e3182934b31 pmid:23733126 pmcid:PMC3786182 fatcat:ch2opy4lpzayriay4t2h2gbzhu

Transcranial stimulability of phosphenes by long lightning electromagnetic pulses

J. Peer, A. Kendl
2010 Physics Letters A  
For typical ranges of stronger than average lightning currents, electric fields above the threshold for cortical phosphene stimulation can be induced only for short distances (order of meters), or in medium  ...  Kendl): The comparison of electric fields transcranially induced by lightning discharges and by TMS brain stimulators via View E = - dA/dt is shown to be inappropriate.  ...  Thomas Kammer (Head of the Laboratory for Transcranial Magnetic Stimulation), Department of Psychiatry, University of Ulm (Germany), for valuable discussions, advice and careful reading of the manuscript  ... 
doi:10.1016/j.physleta.2010.05.023 fatcat:m6ol2igelvgytbhwbpdcuy4vpa

Noninvasive Brain Stimulation with Low-Intensity Electrical Currents: Putative Mechanisms of Action for Direct and Alternating Current Stimulation

Soroush Zaghi, Mariana Acar, Brittney Hultgren, Paulo S. Boggio, Felipe Fregni
2009 The Neuroscientist  
Transcranial stimulation with weak direct current (DC) has been valuable in exploring the effect of cortical modulation on various neural networks.  ...  Reviewing and discussing these methods simultaneously with special attention to what is known about their mechanisms of action may provide new insights for the field of noninvasive brain stimulation.  ...  1 Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Acknowledgements We acknowledge the Berenson-Allen Foundation and American Heart Association for partially funding this project.  ... 
doi:10.1177/1073858409336227 pmid:20040569 fatcat:7itgiv7wrvhybnsgov7dzro2fa

Forgetting fear associations through tES: which memory process might be critical?

C M Vicario, M A Nitsche, K Felmingham
2017 Translational Psychiatry  
In their study, Abend and colleagues examined the effects of two different types of non-invasive transcranial electrical stimulation (tES; that is, direct current (DC) and alternating current (AC) stimulation  ...  Diagram of transcranial electrical stimulation (tES) effects on memory processes (that is, encoding and consolidation) during and after the extinction phase.  ...  In their study, Abend and colleagues examined the effects of two different types of non-invasive transcranial electrical stimulation (tES; that is, direct current (DC) and alternating current (AC) stimulation  ... 
doi:10.1038/tp.2017.26 pmid:28244982 pmcid:PMC5545646 fatcat:blcimeeybrdvleb6p2kvl6i4z4

Physiological and modeling evidence for focal transcranial electrical brain stimulation in humans: A basis for high-definition tDCS

Dylan Edwards, Mar Cortes, Abhishek Datta, Preet Minhas, Eric M. Wassermann, Marom Bikson
2013 NeuroImage  
We aimed to: (1) validate a computational model for estimating cortical electric fields in human transcranial stimulation, and (2) assess the magnitude and spread of cortical electric field with a novel  ...  In three healthy adults, Transcranial Electrical Stimulation (TES) over primary motor cortex (M1) was delivered using the 4×1 montage (4× cathode, surrounding a single central anode; montage radius~3 cm  ...  The adaptor measured resistance prior to stimulation, and divided current during stimulation.  ... 
doi:10.1016/j.neuroimage.2013.01.042 pmid:23370061 pmcid:PMC4359173 fatcat:2mqsifi6dzcszbwn47lhrozl5q

Cortical mapping with navigated transcranial magnetic stimulation in low-grade glioma surgery

Wellingson Paiva, Okada, SOARES, Cabrera, Teixeira
2012 Neuropsychiatric Disease and Treatment  
To determine the accuracy of this new method, we compared TMS mapping with the gold standard mapping with direct cortical electrical stimulation in surgery.  ...  The mean distance between TMS and direct cortical electrical stimulation (DES) was 4.16 ± 1.02 mm (range: 2.56-5.27 mm).  ...  of the referencing procedure of the head in space and of the head during MRI, and on the properties of the electric field and its effect on the cortex. 16 Slices in the T1-weighted MRI scan were used  ... 
doi:10.2147/ndt.s30151 pmid:22665996 pmcid:PMC3363137 fatcat:3sjljun6zzdtrprh3mjx4qey6q

Towards precise brain stimulation: Is electric field simulation related to neuromodulation?

Daria Antonenko, Axel Thielscher, Guilherme Bicalho Saturnino, Semiha Aydin, Bernd Ittermann, Ulrike Grittner, Agnes Flöel
2019 Brain Stimulation  
Recent research on neural and behavioral consequences of transcranial direct current stimulation (tDCS) has highlighted the impact of individual factors, such as brain anatomy which determines current  ...  field distribution and may thus significantly impact stimulation effects.  ...  The authors thank Angelica Sousa for help with data acquisition and Peter Jagd Sørensen for support in Matlab-based scripting.  ... 
doi:10.1016/j.brs.2019.03.072 pmid:30930209 fatcat:cxvvyyhrujhfvalktgckojettm

Electromagnetic Therapy for Neurological and Neurodegenerative Diseases: I Peripheral Brain Stimulations

Alain L Fymat
2019 Open access Journal of Neurology & Neurosurgery  
As of 2015, transcranial direct current stimulation (a Class III device) has not been approved for any use in the U.S.  ...  Electrical and magnetic field currents can produce functionally reversible stimulations. This property has been used for diagnostic and therapeutic neurosurgical procedures.  ...  In the brain, it produces currents in the induced electrical field lying parallel to the plane of the coil.  ... 
doi:10.19080/oajnn.2019.12.555833 fatcat:iby65vg6a5fbxd6hsuikfzhu2a

Consensus: New methodologies for brain stimulation

Ying-Zu Huang, Martin Sommer, Gary Thickbroom, Masashi Hamada, Alvero Pascual-Leonne, Walter Paulus, Joseph Classen, Angel V. Peterchev, Abraham Zangen, Yoshikazu Ugawa
2009 Brain Stimulation  
In this paper, we focus on theta burst stimulation (TBS), repetitive monophasic pulse stimulation, paired-and quadri-pulse stimulation, transcranial alternating current stimulation (tACS), paired associative  ...  For every method, we summarize the state of the art and discuss issues that remain to be addressed.  ...  Transcranial alternating current stimulation The first systematic study to demonstrate interference with brain rhythms as seen in the electroencephalogram (EEG) by non-invasive modulation of motor cortex  ... 
doi:10.1016/j.brs.2008.09.007 pmid:20633398 pmcid:PMC5507351 fatcat:5n24gseblbbwnel2ip4vulprcy

Open questions on the mechanisms of neuromodulation with applied and endogenous electric fields

Shennan A. Weiss, Marom Bikson
2014 Frontiers in Human Neuroscience  
of transcranial stimulation of the cortex.  ...  The exploration of transcranial Direct Current Stimulation (tDCS) and transcranial Alternative Current Stimulation (tACS) over the past decade for both treatment and to enhance cognitive performance and  ...  Citation : Weiss SA and Bikson M (2014) Open questions on the mechanisms of neuromodulation with applied and endogenous electric fields. Front. Hum.  ... 
doi:10.3389/fnhum.2014.00227 pmid:24860463 pmcid:PMC4029019 fatcat:53nyne3t2jalzhmnujwf7j4qja

Electrode montages for tDCS and weak transcranial electrical stimulation: Role of "return" electrode's position and size

M. Bikson, Abhishek Datta, Asif Rahman, Jen Scaturro
2010 Clinical Neurophysiology  
Random Noise Stimulation (tRNS); specifically they demonstrate that during weak transcranial electrical stimulation, the position of the ''return" electrode affects neuro-modulation under the ''active  ...  The position of stimulating electrodes governs current flow through the body, and hence the distribution of induced electric fields in the brain.  ... 
doi:10.1016/j.clinph.2010.05.020 pmid:21035740 pmcid:PMC2983105 fatcat:53bvl33nrzgzbjhjotm2guvcpq

Transcranial Electrical Stimulation [chapter]

Ingrid Moreno-Duarte, Nigel Gebodh, Pedro Schestatsky, Berkan Guleyupoglu, Davide Reato, Marom Bikson, Felipe Fregni
2014 The Stimulated Brain  
While the resulting electric fields are low intensity (for comparison, TMS produces an almost 100-V/m electric field), the sustained electric field produced during tDCS will modify the transmembrane neuronal  ...  THE BASIS .TRANSCRANIAL ELECTRICAL STIMULATION (tES) .TRANSCRANIAL ELECTRICAL STIMULATION (tES) I. THE BASIS .TRANSCRANIAL ELECTRICAL STIMULATION (tES) I.  ... 
doi:10.1016/b978-0-12-404704-4.00002-8 fatcat:iz6hvji4zfdojpx2t5zqvlpxae

Can Transcranial Electrical Stimulation Localize Brain Function?

Anke Ninija Karabanov, Guilherme Bicalho Saturnino, Axel Thielscher, Hartwig Roman Siebner
2019 Frontiers in Psychology  
Transcranial electrical stimulation (TES) uses constant (TDCS) or alternating currents (TACS) to modulate brain activity.  ...  Most TES studies apply low-intensity currents through scalp electrodes (≤2 mA) using bipolar electrode arrangements, producing weak electrical fields in the brain (<1 V/m).  ...  INTRODUCTION Transcranial electric stimulation (TES) applies weak electric currents to non-invasively stimulate the human brain.  ... 
doi:10.3389/fpsyg.2019.00213 pmid:30837911 pmcid:PMC6389710 fatcat:cnqs3u4s4ndwdmv2emyk2o44zq
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