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The Challenges of In Situ Analysis for Multiple Simulations

Alejandro Ribés, Bruno Raffin
2020 ISAV'20 In Situ Infrastructures for Enabling Extreme-Scale Analysis and Visualization  
In situ analysis and visualization have mainly been applied to the output of a single large-scale simulation.  ...  We then discuss the forthcoming challenges, which future in situ analysis and visualization frameworks will face when dealing with the exascale execution of multiple simulations.  ...  ACKNOWLEDGEMENT This work has been partly funded by the European Union's Horizon 2020 research and innovation program under grant agreement No 824158 (EoCoE-2).  ... 
doi:10.1145/3426462.3426468 fatcat:tvev2rwokfekddluojbhgvc35i

FORMULATION AND DETAILED CHARACTERIZATION OF VORICONAZOLE LOADED IN SITU GELS FOR OCULAR APPLICATION

Neslihan ÜSTÜNDAĞ OKUR, Vildan YOZGATLI, Zeynep ŞENYİĞİT
2020 Ankara Universitesi Eczacilik Fakultesi Dergisi  
Result and Discussion: The results showed that the optimized in situ gel formulation had desired in vitro properties and a good stability over the period of 3 months.  ...  The formulations were characterized in terms of their clarity, pH, viscosity drug content uniformity and mechanical/rheological properties.  ...  ACKNOWLEDGEMENTS The authors would like to thank to the BASF for providing the poloxamers.  ... 
doi:10.33483/jfpau.586590 fatcat:edcwbffisfgrdm7pq3eegevl34

Visualize reservoir aging by 4D seismic: A case study for the Snorre oil field in the North Sea
北海スノーレ油田を対象とした4D震探による油層経年変化可視化の試み

Futoshi Tsuneyama
2009 Journal of the Japanese Association for Petroleum Technology  
Afterwards, a sequence of rock-physics theories is applied to transform the resultant properties into the bulk modulus and density of the in-situ fluid.  ...  As a case study, the workflow successfully visualized the change in fluid saturation based on an actual 4D seismic dataset of the Snorre oil field in the North Sea.  ...  Fig. 3 Fig. 8 Fig. 9 Fig. 8 98 The workflow to derive the density and bulk modulus of in-situ fluid.  ... 
doi:10.3720/japt.74.71 fatcat:niub4ookuzatzg5nbemffsjqgi

Lessons Learned from Building In Situ Coupling Frameworks

Matthieu Dorier, Matthieu Dreher, Tom Peterka, Justin M. Wozniak, Gabriel Antoniu, Bruno Raffin
2015 Proceedings of the First Workshop on In Situ Infrastructures for Enabling Extreme-Scale Analysis and Visualization - ISAV2015  
Over the past few years, the increasing amounts of data produced by large-scale simulations have motivated a shift from traditional offline data analysis to in situ analysis and visualization.  ...  This self-critical inquiry aims to shed light not only on their potential, but most importantly on the forthcoming software challenges that these and other in situ analysis and visualization frameworks  ...  This work was done in the framework of a collaboration between the KerData joint Inria -ENS Rennes -Insa Rennes team and Argonne National Laboratory within the Joint Laboratory for Extreme-Scale Computing  ... 
doi:10.1145/2828612.2828622 dblp:conf/sc/DorierDPWAR15 fatcat:vclffn2fu5c5ba5rcuys7qiimq

Elastic fibers: The missing key to improve engineering concepts for reconstruction of the Nucleus Pulposus in the intervertebral disc

Javad Tavakoli, Ashish D. Diwan, Joanne L. Tipper
2020 Acta Biomaterialia  
STATEMENT OF SIGNIFICANCE: Visualization of elastic fibers in the nucleus of the intervertebral disk under high magnification was not reported before.  ...  While our quantitative analysis for measurement of the thickness of elastic fibers revealed no significant differences (p < 0.633), the preferential orientation of fibers was found to be significantly  ...  to visualize their ultrastructure in situ [43] [44] [45] .  ... 
doi:10.1016/j.actbio.2020.06.008 pmid:32531396 fatcat:vwuu57rmknbkzk2hn35b675e44

Volumetric imaging of human mesenchymal stem cells (hMSCs) for non-destructive quantification of 3D cell culture growth [article]

Oscar R Benavides, Holly Gibbs, Berkley P White, Roland Kaunas, Carl Gregory, Kristen C Maitland
2022 bioRxiv   pre-print
The use of spherical microcarriers, however, precludes in-process visualization and monitoring of cell number, morphology, and culture health.  ...  The presented study motivates the development of on-line optical imaging and image analysis systems for robust, automated, and non-destructive monitoring of bioreactor-microcarrier cell cultures.  ...  Acknowledgements We thank the Texas A&M University Microscopy and Imaging Center Core Facility (RRID:SCR_022128) for providing the Zeiss Z1 Lightsheet microscope, Imaris image analysis software, and the  ... 
doi:10.1101/2022.09.19.508168 fatcat:o45q2762kjb2fjrvcnh7cxze5m

In Situ Characterization of Damage Development in Cottonid Due to Quasi-Static Tensile Loading

Ronja Scholz, Alexander Delp, Frank Walther
2020 Materials  
In the elastic region, no visible damage initiation on the surface and a decrease of overall void volume within the gauge length could be detected.  ...  in situ testing techniques for the first time.  ...  Further, the authors thank the Ernst Krüger GmbH & Co. KG, Manfred Joseph, for providing "Hornex" material. Conflicts of Interest: The authors declare no conflicts of interest.  ... 
doi:10.3390/ma13092180 pmid:32397473 fatcat:avqrx4gqu5hrzm6wut6aiwfftu

4D Characterization of Deformation Processes in Aluminum Foams: New Dimensions in Materials Engineering

Jeff Gelb, Allen Gu, Arno Merkle, Leah Lavery
2014 Microscopy and Microanalysis  
Here, the technique of X-ray microscopy (XRM) is employed featuring a compression cell that allows for in-situ mechanical testing and microstructure observation, producing a 4D dataset that relates 3D  ...  observed, spanning up to several hundred newtons of compression (data analysis is performed for the uncompressed to 200N compression state, but high compression levels will be visualized up to 400N).  ...  The solid, shaded areas at the top and bottom of each image are the jaws of the in-situ load cell as the pore space deforms.  ... 
doi:10.1017/s1431927614005959 fatcat:eljpmkg4n5bkvjzc74z6aidlmm

Long-term Morphofunctional Remodeling of Internal Thoracic Artery Grafts: A Frequency-Domain Optical Coherence Tomography Study

I. Porto, M. Gaudino, G. L. De Maria, L. Di Vito, R. Vergallo, P. Bruno, G. Bonalumi, F. Prati, L. Bolognese, F. Crea, M. Massetti
2013 Circulation. Cardiovascular Interventions  
of the grafted left ITA (LITA) with the native, nonharvested right ITA (RITA) in the same patient.  ...  The purpose of this research was to investigate in vivo the long-term morphofunctional changes of ITAs after their use as coronary artery bypass conduits, by comparing the morphological features and vasoreactivity  ...  Acknowledgments The authors would like to thank all the members of the Coronary Care Unit, Catheterization Laboratory, and Cardiac Surgery ward of the Policlinico A.  ... 
doi:10.1161/circinterventions.113.000200 pmid:23716001 fatcat:suw7w3ljafccbbcbauome7xpru

HEMNMA-3D: Cryo Electron Tomography Method Based on Normal Mode Analysis to Study Continuous Conformational Variability of Macromolecular Complexes

Mohamad Harastani, Mikhail Eltsov, Amélie Leforestier, Slavica Jonic
2021 Frontiers in Molecular Biosciences  
The elastic matching combines molecular mechanics simulation (Normal Mode Analysis of the 3D reference) and experimental, subtomogram data analysis.  ...  Its potential of providing information on the dynamics of macromolecular complexes in cells is still largely unexploited, due to the challenges of the data analysis.  ...  ACKNOWLEDGMENTS MH and SJ thank the Scipion team (CNB-CSIC, Madrid, Spain) for the help with porting the HEMNMA-3D code from Scipion V2.0 to Scipion V3.0, and Ilyes Hamitouche and Rémi Vuillemot (IMPMC-UMR  ... 
doi:10.3389/fmolb.2021.663121 pmid:34095222 pmcid:PMC8170028 fatcat:dbi5rgqegfglfezhbjkhtshpvq

In-situ dynamic force calibration using impact hammers

M. Kobusch, L. Klaus
2020 ACTA IMEKO  
The paper describes the analysis of the measurement data and presents the force transfer functions obtained. Finally, these dynamic calibration results are discussed.  ...  This paper presents experimental investigations of in-situ dynamic force calibrations in which an impact hammer provides the dynamic reference force.  ...  Further information on the theory and practice of dynamic measurements and modal analysis by means of impact hammers can be found in [6, 7] .  ... 
doi:10.21014/acta_imeko.v9i5.952 fatcat:fuoeocfn4zd4zd24u4s6h6h564

In situ assembly of the collagen–polyacrylamide interpenetrating network hydrogel: Enabling decoupled control of stiffness and degree of swelling

Kwanghyun Baek, Nicholas E. Clay, Ellen C. Qin, Kathryn M. Sullivan, Dong Hyun Kim, Hyunjoon Kong
2015 European Polymer Journal  
undesirable inverse dependency between the degree of swelling and elastic modulus.  ...  The resulting IPN gel successfully demonstrated the independency between the degree of swelling and the elastic modulus.  ...  To visualize the actin filaments and nuclei of the cells adhered on the hydrogel, the cells were incubated with Alexa Fluor 488 phalloidin and DAPI following In situ assembly of PAAm-collagen IPN gel  ... 
doi:10.1016/j.eurpolymj.2015.07.044 fatcat:6p34x5vmabegvl2n6pfuxglbeu

Health Monitoring of Civil Infrastructure and Materials

Dimitrios G. Aggelis, Ninel Alver, Hwa Kian Chai
2014 The Scientific World Journal  
The assessment based on the above-mentioned methods as well as a number of others, like acoustic emission, radiography, vibration modal analysis, and slightly destructive surface strength methods in conjunction  ...  Indeed, the reliability of in situ implementation is a key issue for any health monitoring technique along with other characteristics such as testing speed and cost-effectiveness.  ... 
doi:10.1155/2014/435238 pmid:24701167 pmcid:PMC3950360 fatcat:he3c4pmdvjgzdho65rnjc5tdae

Confocal Brillouin microscopy for three-dimensional mechanical imaging

Giuliano Scarcelli, Seok Hyun Yun
2007 Nature Photonics  
Furthermore, we report the first in situ biomechanical measurement of the crystalline lens in a mouse eye.  ...  Using the system, we show the first cross-sectional Brillouin imaging based on elastic properties as the contrast mechanism and monitor fast dynamic changes in elastic modulus during polymer crosslinking  ...  Acknowledgements This work was supported by the US Department of Defense (FA9550-04-1-0079) and the Center for Integration of Medicine and Innovative Technologies (CIMIT). We thank P.  ... 
doi:10.1038/nphoton.2007.250 pmid:19812712 pmcid:PMC2757783 fatcat:csuflaczbfcgdjgypjr5zvbkky

Tensile rupture of medial arterial tissue studied by X-ray micro-tomography on stained samples

Clémentine Helfenstein-Didier, Damien Taïnoff, Julien Viville, Jérôme Adrien, Éric Maire, Pierre Badel
2018 Journal of The Mechanical Behavior of Biomedical Materials  
Detailed characterization of damage and rupture mechanics of arteries is one the current challenges in vascular biomechanics, which requires developing suitable experimental approaches.  ...  This paper introduces an approach using in situ tensile tests in an X-ray micro-tomography setup to observe mechanisms of damage initiation and progression in medial layers of porcine aortic samples.  ...  Acknowledgements This work was supported by the European Research Council [starting grant n°638804, AArteMIS].  ... 
doi:10.1016/j.jmbbm.2017.11.032 pmid:29207329 fatcat:7zjyf3w37vfd3e4szjyhofq3qa
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