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Future Projections and Fallouts of Exponential Longevity and Revival from Cryopreservation
2018
Research in Medical & Engineering Sciences
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The incredible advances in the field of medical science have made possible to cure acute disorders and chronic diseases, and avoid frailty, complications and untimely demise. ...
The lifespan of organisms, including human beings, is not fixed but limited [1] . ...
The cells possess a number of systems for functional and structural maintenance and repair. In fact, the DNA-repair capability correlates well with the lifespan of a species. ...
doi:10.31031/rmes.2018.06.000641
fatcat:beszsjz5rzd5fhiefaoelbznyq
Software evolution: the lifetime of fine-grained elements
2021
PeerJ Computer Science
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We present methods and tools that allow tracking of each line's or token's birth and death. ...
of software development. ...
This work's first author thanks Michiel van Genuchten and Les Hatton for their fruitful collaboration on software growth modeling. ...
doi:10.7717/peerj-cs.372
pmid:33817021
pmcid:PMC7959608
fatcat:v3yr43mxnbee7h34klnmryppf4
The importance of life cycle on the future development of tourist destination
2019
CES Working Papers
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The research aims to identify the phase of the life cycle in which the destination is currently located, according to the Batler model, and to measure the achievement of ecological and economic sustainability ...
The work analyses the theoretical phases of the life cycle of touristic destinations and presents the results of the research Case study: Nature Park Zlatibor - the most visited touristic destination. ...
The life cycle is based on the comparison with living being which life is characterized by two extreme occurrences: birth and disappearance (death). ...
doaj:53bab6db55e04bb2a8e2c5a02a70afbd
fatcat:3okawco7pfgxpbu6ukkzgavo4a
Two stochastic processes shape diverse senescence patterns in a single-cell organism
[article]
2017
bioRxiv
pre-print
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the lack of a mother offspring correlation in age at death. ...
This second process is required to explain the difference between the classical mortality plateaus detected for young mothers' offspring and the near non-senescence of old mothers' offspring as well as ...
transition rate and the 843 death rate, respectively. 844 µ0=a+c, the death rate at birth i.e. state i=0, 845 . ...
doi:10.1101/105387
fatcat:pwlhhdwqazgmtafe47si4u4k7a
How to Build and to Protect the Neuromuscular Junction: The Role of the Glial Cell Line-Derived Neurotrophic Factor
2020
International Journal of Molecular Sciences
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Historically related to the maintenance and survival of dopaminergic neurons of the substantia nigra, GDNF also plays a fundamental role in the peripheral NS (PNS). ...
Indeed, signals originating from the muscle play an important role in synapse formation, stabilization, maintenance and function, both in development and adulthood. ...
, and the rescue of neurons from axotomyinduced cell death [16] . ...
doi:10.3390/ijms22010136
pmid:33374485
fatcat:oafl7x2udbfbvp4nuxxipoeicm
Optimization Culture Conditions of Differentiating Endothelial Progenitor Cells From Human Mononuclear Cells in Vitro
2019
Biomedical Journal of Scientific & Technical Research
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The experimental results confirmed that the vitOrgan drug contains 123 cytokines, including ACE2, and ULBP2. ...
However, the molecular mechanisms involved remain unclear and underresearched. ...
research data of vitOrgan with the research community. ...
doi:10.26717/bjstr.2019.15.002640
fatcat:4nv46rdyjngw7m2umu3lsxa6ai
Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway
2018
Nature Communications
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The development, growth, and renewal of skeletal tissues rely on the function of osteochondroprogenitors (OCPs). ...
Our data reveals a crucial role of the SENP6-p53 axis in maintaining OCP homeostasis during skeletal development. ...
Acknowledgements We thank the members of the Yang laboratory and other members of the Program for Skeletal Disease and Tumor Metastasis at Van Andel Research Institute for discussion; Drs. ...
doi:10.1038/s41467-017-02413-3
pmid:29321472
pmcid:PMC5762923
fatcat:jadauvkb35bolglnqouum5fugu
The Social Economy as a Factor of Economic Development and Resilience of Population in Rural Areas. A Study of Mediating Effects in Castilla-La Mancha (Spain)
2021
Sustainability
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growth. ...
entities helps to anchor population and increase the resilience of this territory. ...
The first, understood as the population variation due to the difference between live births and deaths, is mainly motivated by both the reduction of birth rates [46] , and the high aging rates of the ...
doi:10.3390/su13105544
fatcat:iad6b5plwzdorfu4anjmqgtjvu
Status of women and family planning: the Indian case
1989
Asia-Pacific Population Journal
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in household affairs is positively correlated with the degree of awareness and knowledge of contraceptives as well as adoption of family planning; and 3) interspousal communication was significantly related ...
It uses both macro-level data for the states of India and date from household surveys and field studies to assess the extent of interaction between the women's status indicators and family planning indicators ...
Growth of the elderly in India Until the year 1951, the sequence of high birth rates followed by high death rates kept the proportion of the persons aged 60 and above at a low level in India. ...
pmid:12316023
fatcat:ueo233dxzfcvrhkeaxqhgnkpwm
Overexpression of Atg5 in mice activates autophagy and extends lifespan
2013
Nature Communications
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Our observations suggest that the leanness and lifespan extension in Atg5 transgenic mice may be the result of increased autophagic activity. ...
Furthermore, mouse embryonic fibroblasts cultured from Atg5 transgenic mice are more tolerant to oxidative damage and cell death induced by oxidative stress, and this tolerance was reversible by treatment ...
Kaplan-Meier survival curves were constructed using known birth and death dates, and differences between groups were evaluated using the logrank test. ...
doi:10.1038/ncomms3300
pmid:23939249
pmcid:PMC3753544
fatcat:lkpd57xburcc7o2xkarzlocrpi
Ideal Technology Concept & Its Realization Opportunity Using Nanotechnology
2015
Zenodo
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The concept of ideal engine, ideal switch, ideal semiconductor devices like ideal diodes, transistors, etc. have been defined and taken as standards to improve the quality and performance of such practical ...
Based on the discussion, it is realized that many of the characteristics of ideal technology are achievable through discoveries and innovations in Nanotechnology. ...
The preliminary report of the isolation of these cells marked the birth of the new area of research called regenerative medicine. ...
doi:10.5281/zenodo.61591
fatcat:cttlixvsajdo5f5zpofbkyu7su
Rejuvenescence American Style: Longevity, Aging, The US Tradition of Rejecting the Old & the US Baby Boom Generation Now
2015
Transatlantica : Revue d'Études Américaines
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Specially the issue of rejuvenating surgery for the human body. ...
functional delivery system and as a software, wetware conveyor of emotions -and how the popular culture which is purveyed by media corporations acutely function as the "folklore of industrial mankind" ...
the application of science to develop solutions to health problems or issues, such as the prevention or delay of onset of disease, or the promotion and monitoring of good health. ...
doi:10.4000/transatlantica.7441
fatcat:tqwxgtcehfgatm7vp3zhlc4gjq
Free-Roaming Dogs Control Activities in One Italian Province (2000-2013): Is the Implemented Approach Effective?
2015
Macedonian Veterinary Review
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The aim of this retrospective study was to describe the local FRD population, identifying its source and to evaluate the effectiveness of the actions implemented by the local authorities. ...
Results highlighted a lack of responsibility of owners by failing to sterilise and identify their dogs and allowing intact animals to roam free, therefore producing uncontrolled and unwanted litters. ...
The present results highlight a high entrance rate of sub-adult animals (around 1 y.o., Fig. 2 ) and a rejuvenation of the population across the years (Fig. 3) . ...
doi:10.14432/j.macvetrev.2015.04.041
fatcat:wsylylc7zzd3ji7hnjjtd7glze
EMPOWERING ENTREPRENEURSHIP IN FEMALE RUN ICT ENTERPRISES: A STUDY IN KERLA
2015
JOURNAL OF SOCIAL SCIENCE RESEARCH
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But this article is focusing on the inclusion of gender in policies relating to information and communication technology with the aim of empowering women as users and producers of this technology. ...
It is built around three pillars of economic, social and womens empowerment. Its formation was the culmination of a process of community mobilization taken up by the State Government. ...
And through these contacts which they have developed over time now they are trying to get private sector jobs, for example, two of the units have worked as hospital kiosk to enter death and birth details ...
doi:10.24297/jssr.v7i2.3568
fatcat:qtj3umggk5etjbdbf7duemnefq
Ideal Systems, Ideal Technology and their Realization Opportunities Using Information Communication & Computation Technology (ICCT) and Nanotechnology (NT)
2021
Zenodo
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The developments and progress in society depend on the improvements in the performance of every system and innovations in technology. ...
Technology management is an area of predicting, identifying, managing, and utilising existing and new technologies for the benefit of people, organizations, and society. ...
Green technologies support the use of natural ...
doi:10.5281/zenodo.4709634
fatcat:bvx7d7aax5aatnlayvnhuaozke
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