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The Universal Protein Resource (UniProt)

A. Bairoch
2004 Nucleic Acids Research  
UniProt/Swiss-Prot activities at the SIB are supported by the Swiss Federal Government through the Federal Office of Education and Science.  ...  ACKNOWLEDGEMENTS UniProt is mainly supported by the National Institutes of Health (NIH) grant 1 U01 HG02712-01.  ...  In 2002, the Swiss-Prot + TrEMBL groups at the SIB (Swiss Institute of Bioinformatics) and EBI (European Bioinformatics Institute) and the PIR (Protein Information Resource) group at Georgetown University  ... 
doi:10.1093/nar/gki070 pmid:15608167 pmcid:PMC540024 fatcat:iqjosikdt5epfo6inmhb5uuiyy

The Universal Protein Resource (UniProt)

2007 Nucleic Acids Research  
The primary mission of UniProt is to support biological research by maintaining a stable, comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with extensive  ...  cross-references and querying interfaces freely accessible to the scientific community.  ...  Classification Database UCSC University of California Santa Cruz Genome Browser XenBase Xenopus laevis and tropicalis biology and genomics resource Controlled vocabularies Controlled vocabularies  ... 
doi:10.1093/nar/gkm895 pmid:18045787 pmcid:PMC2238893 fatcat:pbq7vsuwtfafzco3f5dcfipvba

The Universal Protein Resource (UniProt)

2007 Nucleic Acids Research  
The Universal Protein Resource (UniProt) provides a stable, comprehensive, freely accessible, central resource on protein sequences and functional annotation.  ...  The UniProt Consortium is a collaboration between the European Bioinformatics Institute (EBI), the Protein Information Resource (PIR) and the Swiss Institute of Bioinformatics (SIB).  ...  ACKNOWLEDGEMENTS UniProt is mainly supported by the National Institutes of Health (NIH) grant 2 U01 HG02712-05.  ... 
doi:10.1093/nar/gkl929 pmid:17142230 pmcid:PMC1669721 fatcat:3doko4bysfhmzddimueyp2tj3y

The Universal Protein Resource (UniProt) in 2010

2009 Nucleic Acids Research  
The primary mission of UniProt is to support biological research by maintaining a stable, comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with extensive  ...  cross-references and querying interfaces freely accessible to the scientific community.  ...  Additional support for the EBI's involvement in UniProt comes from the European Commission contract SLING grant  ... 
doi:10.1093/nar/gkp846 pmid:19843607 pmcid:PMC2808944 fatcat:zzpkffi7h5aipaogu36t35y77q

Activities at the Universal Protein Resource (UniProt)

2013 Nucleic Acids Research  
human and mouse transcription factors by the Systems Biology team at the Norwegian University of Science and Technology (NTNU).  ...  UniProtKB has >140 cross-references to other resources. Some notable additions in the last year are GeneWiki (23) and the Protein Ontology (24) .  ... 
doi:10.1093/nar/gkt1140 pmid:24253303 pmcid:PMC3965022 fatcat:ymvqbpyhizafba7upcn222a6ty

The Universal Protein Resource (UniProt): an expanding universe of protein information

C. H. Wu
2006 Nucleic Acids Research  
The Universal Protein Resource (UniProt) provides a central resource on protein sequences and functional annotation with three database components, each addressing a key need in protein bioinformatics.  ...  Finally, the UniProt Archive (UniParc) stores all publicly available protein sequences, containing the history of sequence data with links to the source databases.  ...  ACKNOWLEDGEMENTS UniProt is mainly supported by the National Institutes of Health (NIH) grant 1 U01 HG02712-01.  ... 
doi:10.1093/nar/gkj161 pmid:16381842 pmcid:PMC1347523 fatcat:6xrpacost5entptndstyr7gnry

Reorganizing the protein space at the Universal Protein Resource (UniProt)

2011 Nucleic Acids Research  
The mission of UniProt is to support biological research by providing a freely accessible, stable, comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with  ...  UniProt is comprised of four major components, each optimized for different uses: the UniProt Archive, the UniProt Knowledgebase, the UniProt Reference Clusters and the UniProt Metagenomic and Environmental  ...  The UniProt Archive (UniParc) (1) is a comprehensive sequence repository, reflecting the history of all protein sequences.  ... 
doi:10.1093/nar/gkr981 pmid:22102590 pmcid:PMC3245120 fatcat:tpdi3er7yrdk7me7g3xmy6n3wy

Update on activities at the Universal Protein Resource (UniProt) in 2013

2012 Nucleic Acids Research  
INTRODUCTION The UniProt's goal is to provide the most comprehensive resource for protein sequence and functional annotation.  ...  Altogether, the UniProt supplied automatic annotation pipelines provide 42.5 million annotations to >14 million proteins.  ... 
doi:10.1093/nar/gks1068 pmid:23161681 pmcid:PMC3531094 fatcat:pfzlr46jqfdlvfjtjlznfmkqsm

UniProt archive

R. Leinonen, F. G. Diez, D. Binns, W. Fleischmann, R. Lopez, R. Apweiler
2004 Bioinformatics  
UniProt Archive (UniParc) is the most comprehensive, non-redundant protein sequence database available. Its protein sequences are retrieved from predominant, publicly accessible resources.  ...  When proteins are loaded into the database, database cross-references are created to link them to the origins of the sequences.  ...  INTRODUCTION Universal Protein Knowledgebase (UniProt) is a central database of protein sequences and functions created by joining the information in SWISS-PROT (Boeckmann et al., 2003) , TrEMBL (Boeckmann  ... 
doi:10.1093/bioinformatics/bth191 pmid:15044231 fatcat:iz22xro7efb33aadhqfagnpigm

Ongoing and future developments at the Universal Protein Resource

2010 Nucleic Acids Research  
INTRODUCTION Universal Protein Resource (UniProt) strives to provide a centralized repository of protein sequences with comprehensive coverage and a systematic approach to protein annotation, incorporating  ...  The additional bibliography is directly linked from the protein entry view on the UniProt web site.  ... 
doi:10.1093/nar/gkq1020 pmid:21051339 pmcid:PMC3013648 fatcat:vhmcewdzlrfndn3fmtafewqbxa

UniProt Protein Knowledgebase [chapter]

Sangya Pundir, Maria J. Martin, Claire O'Donovan
2017 Msphere  
The Universal Protein Resource (UniProt) is a freely available comprehensive resource for protein sequence and annotation data.  ...  UniProt is a collaboration between the European Bioinformatics Institute (EMBL-EBI), the Swiss Institute of Bioinformatics (SIB), and the Protein Information Resource (PIR).  ...  Acknowledgments This work was supported by grant U41HG007822 from the National Institutes of Health.  ... 
doi:10.1007/978-1-4939-6783-4_2 pmid:28150232 pmcid:PMC5565770 fatcat:sem3wywevbcancpfdfx3lvpqse

Searching and Navigating UniProt Databases

Sangya Pundir, Michele Magrane, Maria J. Martin, Claire O'Donovan
2015 Current Protocols in Bioinformatics  
The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data.  ...  The key UniProt datasets are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef) and the UniProt Archive (UniParc) and protein sets for completely sequenced genomes (Proteomes  ...  Acknowledgments This work was supported by the National Institutes of Health [U41HG006104, U41HG007822, U41HG002273, R01GM080646, G08LM010720, P20GM103446]; British Heart Foundation [RG/13/5/30112]; Parkinson's  ... 
doi:10.1002/0471250953.bi0127s50 pmid:26088053 pmcid:PMC4522465 fatcat:o2ggn5ojxvaajfkymbfhifi7vi

Xenopus and Zebrafish Annotation in the UniProt Knowledgebase (UniProtKB)

Rebecca Foulger, UniProt Consortium
2009 Nature Precedings  
Protein Information Resource (PIR) • Xenopus laevis (African clawed frog) and Danio rerio (zebrafish) are both model organisms in the laboratory, as they are easy to accommodate and can produce large numbers  ...  the zebrafish genome in 2001.The extensive similarity between the zebrafish and human genomes means many human developmental and disease genes have counterparts in the zebrafish.  ...  Introduction to UniProtUniProt (Universal Protein Resource: http://www.uniprot.org) provides a central resource of protein sequences with functional annotation.  ... 
doi:10.1038/npre.2009.3153.1 fatcat:d36olesojzc2lht2c3thuocte4

UniProt: the Universal Protein knowledgebase

R. Apweiler
2004 Nucleic Acids Research  
ACKNOWLEDGEMENTS UniProt is supported mainly by the National Institutes of Health (NIH) grant 1 U01 HG02712-01.  ...  Minor support for the EBI's involvement in UniProt comes from the two European Union contracts BioBabel (QLRT-2000-00981) and TEMBLOR (QLRI-2001-00015) and from the NIH grant 1R01HGO2273-01.  ...  In 2002, the Swiss-Prot + TrEMBL group at the Swiss Institute of Bioinformatics (SIB) and European Bioinformatics Institute (EBI) and the Protein Information Resource (PIR) group at the Georgetown University  ... 
doi:10.1093/nar/gkh131 pmid:14681372 pmcid:PMC308865 fatcat:q6fuc2kgujar5drblzqtcbvpou
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