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The Philadelphia Neurodevelopmental Cohort: A publicly available resource for the study of normal and abnormal brain development in youth

Theodore D. Satterthwaite, John J. Connolly, Kosha Ruparel, Monica E. Calkins, Chad Jackson, Mark A. Elliott, David R. Roalf, Ryan Hopson, Karthik Prabhakaran, Meckenzie Behr, Haijun Qiu, Frank D. Mentch (+5 others)
<span title="">2016</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
for studies of normal and abnormal neurodevelopment.  ...  The Philadelphia Neurodevelopmental Cohort (PNC) is a large-scale study of child development that combines neuroimaging, diverse clinical and cognitive phenotypes, and genomics.  ...  Together, the multi-level data of the PNC provides a resource to delineate patterns of normal brain development, describe how abnormal patterns of brain development are related to cognitive dysfunction  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2015.03.056">doi:10.1016/j.neuroimage.2015.03.056</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/25840117">pmid:25840117</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4591095/">pmcid:PMC4591095</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/5ekm73frubemrhg7z62tiqijwi">fatcat:5ekm73frubemrhg7z62tiqijwi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200430123808/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4591095&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/a8/5e/a85eeb57a20d2441becd47d07c07fb2c5d2890cd.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2015.03.056"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591095" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Neuroimaging of the Philadelphia Neurodevelopmental Cohort

Theodore D. Satterthwaite, Mark A. Elliott, Kosha Ruparel, James Loughead, Karthik Prabhakaran, Monica E. Calkins, Ryan Hopson, Chad Jackson, Jack Keefe, Marisa Riley, Frank D. Mentch, Patrick Sleiman (+5 others)
<span title="">2014</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
Thanks to Rosetta Chiavacci for study coordination, and to Larry Macy for systems support. Thanks to James Dickson for XNAT development.  ...  Acknowledgments Many thanks to the acquisition team, including Jeff Valdez, Raphael Gerraty, Nicholas DeLeo, and Elliot Yodh.  ...  Data sharing Establishing the PNC as a publicly available resource for the study of brain development was one of the principal aims of the initiative.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2013.07.064">doi:10.1016/j.neuroimage.2013.07.064</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23921101">pmid:23921101</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3947233/">pmcid:PMC3947233</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/mm6jehpoarctvl3e2wzhr3jlam">fatcat:mm6jehpoarctvl3e2wzhr3jlam</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170829042326/http://nmr.mgh.harvard.edu/~you2/publications/Satterthwaite14.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/4d/1a/4d1ae01cc77abf8b45f26efad252a221cf848d72.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2013.07.064"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947233" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Structural Brain Abnormalities in Youth With Psychosis Spectrum Symptoms

Theodore D. Satterthwaite, Daniel H. Wolf, Monica E. Calkins, Simon N. Vandekar, Guray Erus, Kosha Ruparel, David R. Roalf, Kristin A. Linn, Mark A. Elliott, Tyler M. Moore, Hakon Hakonarson, Russell T. Shinohara (+3 others)
<span title="2016-05-01">2016</span> <i title="American Medical Association (AMA)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/dysoj6ukqzbmnecr2bnq4lry3m" style="color: black;">JAMA psychiatry</a> </i> &nbsp;
DESIGN, SETTING, AND PARTICIPANTS The Philadelphia Neurodevelopmental Cohort is a prospectively accrued, community-based sample of 9498 youth who received a structured psychiatric evaluation.  ...  OBJECTIVE To investigate the presence of structural brain abnormalities in youth with PS symptoms.  ...  The Philadelphia Neurodevelopmental Cohort: a publicly available resource for the study of normal Table . .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1001/jamapsychiatry.2015.3463">doi:10.1001/jamapsychiatry.2015.3463</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26982085">pmid:26982085</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5048443/">pmcid:PMC5048443</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/2bouzaldivckpos2ndlzyp2jgy">fatcat:2bouzaldivckpos2ndlzyp2jgy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190503013353/https://jamanetwork.com/journals/jamapsychiatry/articlepdf/2498836/jamapsychiatry_Satterthwaite_2016_oi_150100.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/c0/bd/c0bdaef59a399e1a1466020b4022c0982ebdbcfd.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1001/jamapsychiatry.2015.3463"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048443" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Association of Heritable Cognitive Ability and Psychopathology With White Matter Properties in Children and Adolescents

Dag Alnæs, Tobias Kaufmann, Nhat Trung Doan, Aldo Córdova-Palomera, Yunpeng Wang, Francesco Bettella, Torgeir Moberget, Ole A. Andreassen, Lars T. Westlye
<span title="2018-03-01">2018</span> <i title="American Medical Association (AMA)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/dysoj6ukqzbmnecr2bnq4lry3m" style="color: black;">JAMA psychiatry</a> </i> &nbsp;
Neurodevelopmental Cohort and analyzed diffusion magnetic resonance imaging brain scans for 748 of the participants.  ...  Question Is brain structural connectivity a sensitive transdiagnostic phenotype for predicting psychiatric symptoms in youth?  ...  Neurodevelopmental Cohort (PNC) study, a large-scale population-based study of brain development in youth that incorporates publicly available data 2,3 to investigate the relationship between brain white  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1001/jamapsychiatry.2017.4277">doi:10.1001/jamapsychiatry.2017.4277</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29365026">pmid:29365026</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5885956/">pmcid:PMC5885956</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/x5bxo7f5gvfynhasngplgnmlyu">fatcat:x5bxo7f5gvfynhasngplgnmlyu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200506060103/https://jamanetwork.com/journals/jamapsychiatry/articlepdf/2670370/jamapsychiatry_alns_2018_oi_170101.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/36/9a/369ab862f29ad5dfe0425e202a65f44040e41683.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1001/jamapsychiatry.2017.4277"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885956" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Developmentally divergent sexual dimorphism in the cortico-striatal–thalamic–cortical psychosis risk pathway

Grace R. Jacobs, Stephanie H. Ameis, Jie Lisa Ji, Joseph D. Viviano, Erin W. Dickie, Anne L. Wheeler, Sonja Stojanovski, Alan Anticevic, Aristotle N. Voineskos
<span title="2019-05-06">2019</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/zscwnf3bera7vcvkm7bgnh2sbu" style="color: black;">Neuropsychopharmacology</a> </i> &nbsp;
We examined effects of sex and age on structural and functional properties of the CSTC circuit in a large sample of youth with and without psychosis spectrum symptoms (PSS) from the Philadelphia Neurodevelopmental  ...  Structural subdivisions of the striatum and thalamus were identified using the MAGeT Brain segmentation tool. Functional seeds were segmented based on brain network connectivity.  ...  Those with psychosis spectrum symptoms (PSS), defined in studies of the Philadelphia Neurodevelopmental Cohort (PNC), may exhibit an even earlier potential risk phenotype than the prodrome.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41386-019-0408-6">doi:10.1038/s41386-019-0408-6</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31060043">pmid:31060043</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6785143/">pmcid:PMC6785143</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/xujuyur6pjhbhovgac5njof22a">fatcat:xujuyur6pjhbhovgac5njof22a</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210429065646/https://www.nature.com/articles/s41386-019-0408-6.pdf?error=cookies_not_supported&amp;code=a531ab9d-cbd8-491d-aaa3-ad86046c8196" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/a0/36/a0366a4c102da35e95937854f15f2545475b60d1.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41386-019-0408-6"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785143" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents [article]

Linn B. Norbom, Jaroslav Rokicki, Dennis van der Meer, Dag Alnaes, Nhat Trung Doan, Torgeir Moberget, Tobias Kaufmann, Ole Andreassen, Lars T. Westlye, Christian K. Tamnes
<span title="2019-12-20">2019</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Human brain development involves spatially and temporally heterogeneous changes, detectable across a wide range of magnetic resonance imaging (MRI) measures.  ...  These results indicate that multimodal fusion is sensitive to age and sex differences in brain structure in youth, but only weakly to polygenic load for neuroticism.  ...  The Philadelphia Neurodevelopmental Cohort: A publicly available resource for the study of normal and abnormal brain development in youth. Neuroimage 2016; 124(Pt B): 1115-1119. 46.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/2019.12.20.883959">doi:10.1101/2019.12.20.883959</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/wl23p2cjura3vaxom5voxxov4q">fatcat:wl23p2cjura3vaxom5voxxov4q</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200711191843/https://www.biorxiv.org/content/biorxiv/early/2020/05/15/2019.12.20.883959.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/c3/6c/c36c5b3cac5ad9e4088c00877394edd21a03141d.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/2019.12.20.883959"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

Modular Segregation of Structural Brain Networks Supports the Development of Executive Function in Youth [article]

Graham L. Baum, Rastko Ciric, David R. Roalf, Richard F. Betzel, Tyler M. Moore, Russel T. Shinohara, Ari E. Kahn, Megan Quarmley, Philip A. Cook, Mark A. Elliot, Kosha Ruparel, Raquel E. Gur, Ruben C. Gur (+2 others)
<span title="2016-08-11">2016</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
In a sample of 882 participants (ages 8-22) who underwent diffusion imaging as part of the Philadelphia Neurodevelopmental Cohort, we demonstrate that structural network modules become more segregated  ...  Together, results delineate a process of structural network maturation that supports executive function in youth.  ...  Support for developing statistical analyses (RTS & TDS) was provided by a seed grant by the Center for Biomedical Computing and Image Analysis (CBICA) at Penn.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1608.03619v1">arXiv:1608.03619v1</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/2bdi3v5c2refzg45wcjsvkkx7i">fatcat:2bdi3v5c2refzg45wcjsvkkx7i</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200825115313/https://arxiv.org/pdf/1608.03619v1.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/e6/3a/e63ace105630e200b21dc45cf661529ed6ef9f92.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1608.03619v1" title="arxiv.org access"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> arxiv.org </button> </a>

Imaging Patterns of Brain Development and their Relationship to Cognition

G. Erus, H. Battapady, T. D. Satterthwaite, H. Hakonarson, R. E. Gur, C. Davatzikos, R. C. Gur
<span title="2014-01-12">2014</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/eeg67t2wzfd3dpiicxsttg3cxi" style="color: black;">Cerebral Cortex</a> </i> &nbsp;
The brain was found to follow a remarkably consistent developmental trajectory in a sample of 621 subjects of ages 8-22 participating in the Philadelphia Neurodevelopmental Cohort, reflected by a cross-validated  ...  These results indicate that the multiparametric imaging patterns summarized by the BDI can accurately delineate trajectories of brain development and identify individuals with cognitive precocity or delay  ...  Notes The authors thank the acquisition team, including James Loughead, Karthik Prabhakaran, Ryan Hopson, Jeff Valdez, Marisa Riley, Jack Keefe, Raphael Gerraty, Nicholas DeLeo, and Elliot Yodh.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/cercor/bht425">doi:10.1093/cercor/bht425</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/24421175">pmid:24421175</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4428302/">pmcid:PMC4428302</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/s7mjt3sftfbnjd547j7tfaxsme">fatcat:s7mjt3sftfbnjd547j7tfaxsme</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190219032920/http://pdfs.semanticscholar.org/14ff/6f25c17c5d134acc389f545a76b9956a9340.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/14/ff/14ff6f25c17c5d134acc389f545a76b9956a9340.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/cercor/bht425"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> oup.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428302" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Mapping Complex Brain Torque Components and Their Genetic and Phenomic Architecture in 24,112 healthy individuals [article]

Lu Zhao, William Matloff, Yonggang Shi, Ryan P. Cabeen, Arthur W. Toga
<span title="2021-03-09">2021</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
The mechanisms determining the development and individual variability of brain torque (BT) remain unclear.  ...  This study provides a comprehensive description of BT and insights into biological and other factors that may contribute to the development and individual variations of BT.  ...  Philadelphia Neurodevelopmental Cohort The Philadelphia Neurodevelopmental Cohort (PNC) is a large-scale initiative that seeks to describe how genetics impact trajectories of brain development and cognitive  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/2021.03.09.434625">doi:10.1101/2021.03.09.434625</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/2q23dcqzvjcqjjktymyjvvmpfm">fatcat:2q23dcqzvjcqjjktymyjvvmpfm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210717133151/https://www.biorxiv.org/content/biorxiv/early/2021/03/30/2021.03.09.434625.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/41/3a/413aca0212c54b507296c8a40f8417ea7614f2ca.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/2021.03.09.434625"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

Subject-level measurement of local cortical coupling

Simon N. Vandekar, Russell T. Shinohara, Armin Raznahan, Ryan D. Hopson, David R. Roalf, Kosha Ruparel, Ruben C. Gur, Raquel E. Gur, Theodore D. Satterthwaite
<span title="">2016</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
Capitalizing on a large cross-sectional sample (n = 932) of youth imaged as part of the Philadelphia Neurodevelopmental Cohort, we demonstrate that local coupling is spatially heterogeneous and exhibits  ...  The human cortex is highly folded to allow for a massive expansion of surface area.  ...  Acknowledgments Thanks for the assistance with data processing (Madhura  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2016.03.002">doi:10.1016/j.neuroimage.2016.03.002</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26956908">pmid:26956908</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4889557/">pmcid:PMC4889557</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/icgx526vbzgonilauf7vwim7yi">fatcat:icgx526vbzgonilauf7vwim7yi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20171002083657/http://publisher-connector.core.ac.uk/resourcesync/data/elsevier/pdf/b3e/aHR0cDovL2FwaS5lbHNldmllci5jb20vY29udGVudC9hcnRpY2xlL3BpaS9zMTA1MzgxMTkxNjAwMTk3eA%3D%3D.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/72/7c/727cc85cf66cb5096fb7360d1b13231150f709ec.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2016.03.002"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889557" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Cerebellar grey matter volume in adolescence is associated with prodromal psychotic symptoms and norm-violating behavior [article]

Torgeir Moberget, Dag Alnaes, Tobias Kaufmann, Nhat Trung Doan, Aldo Cordova-Palomera, Linn Bonaventure Norbom, Jarek Rokicki, Dennis van der Meer, Ole A Andreassen, Lars T Westlye
<span title="2018-03-23">2018</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Conclusions and relevance: The robust associations with sub-clinical psychiatric symptoms in the age range when these typically emerge highlight the cerebellum as a key brain structure in the development  ...  Neurodevelopmental Cohort (N=1401, age-range: 8 - 23).  ...  No reuse allowed without permission. ) (2016): The Philadelphia Neurodevelopmental Cohort: A publicly available resource for the study of normal and abnormal brain development in youth.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/288134">doi:10.1101/288134</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/upr6ulmazrafpjius7ymr2geri">fatcat:upr6ulmazrafpjius7ymr2geri</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190502053428/https://www.biorxiv.org/content/biorxiv/early/2019/01/18/288134.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/6a/f5/6af54a6784856d389b521e0b8d685da2a16d204f.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/288134"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

Modular Segregation of Structural Brain Networks Supports the Development of Executive Function in Youth

Graham L. Baum, Rastko Ciric, David R. Roalf, Richard F. Betzel, Tyler M. Moore, Russell T. Shinohara, Ari E. Kahn, Simon N. Vandekar, Petra E. Rupert, Megan Quarmley, Philip A. Cook, Mark A. Elliott (+5 others)
<span title="">2017</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/waxwzq3cnbet3cmwccpuk4bel4" style="color: black;">Current Biology</a> </i> &nbsp;
In a sample of 882 participants (ages 8-22) who underwent diffusion imaging as part of the Philadelphia Neurodevelopmental Cohort, we demonstrate that structural network modules become more segregated  ...  Finally, such data are a prerequisite for studies of neuropsychiatric disorders, which are increasingly understood as disorders of brain development [27] , are marked by executive dysfunction [28] , and  ...  Thanks to Chad Jackson for data management and systems support and Monica Calkins for phenotyping expertise.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.cub.2017.04.051">doi:10.1016/j.cub.2017.04.051</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28552358">pmid:28552358</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5491213/">pmcid:PMC5491213</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/hfta6qoelzdo5ltgv77gxjopmy">fatcat:hfta6qoelzdo5ltgv77gxjopmy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200210055352/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5491213&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/65/de/65de8fb8536d4e2cbd2173875026aba93b3672a4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.cub.2017.04.051"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491213" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Diminished Cortical Thickness is Associated with Impulsive Choice in Adolescence [article]

Marieta Pehlivanova, Daniel Wolf, Aristeidis Sotiras, Antonia Kaczkurkin, Tyler Moore, Rastko Ciric, Philip Cook, Angel Garcia de La Garza, Adon Rosen, Kosha Ruparel, Anup Sharma, Russell Shinohara (+6 others)
<span title="2017-12-07">2017</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Leveraging a unique large sample of 427 human youths (208 males and 219 females) imaged as part of the Philadelphia Neurodevelopmental Cohort, we examined associations between delay discounting and cortical  ...  One important index of impulsive choice is delay discounting (DD), which measures the tendency to prefer smaller rewards available soon over larger rewards delivered after a delay.  ...  Hakonarson H, Gur RE (2016) The Philadelphia Neurodevelopmental Cohort: a publicly available resource for the study of normal and abnormal brain development in youth. Neuroimage 124:1115-1119.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/230888">doi:10.1101/230888</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/lqjzwao7l5c3pgmn2mhlmx4kya">fatcat:lqjzwao7l5c3pgmn2mhlmx4kya</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190502133239/https://www.biorxiv.org/content/biorxiv/early/2017/12/07/230888.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/2f/75/2f7550345ff515e279dfda24ed019934b9d62e9d.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/230888"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

Heterogeneous impact of motion on fundamental patterns of developmental changes in functional connectivity during youth

Theodore D. Satterthwaite, Daniel H. Wolf, Kosha Ruparel, Guray Erus, Mark A. Elliott, Simon B. Eickhoff, Efstathios D. Gennatas, Chad Jackson, Karthik Prabhakaran, Alex Smith, Hakon Hakonarson, Ragini Verma (+3 others)
<span title="">2013</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
phenotype for the study of neurodevelopment.  ...  Here, in a sample of 780 subjects ages 8-22, we re-evaluate patterns of change in functional connectivity during adolescent development after rigorously controlling for the confounding influences of motion  ...  Acknowledgments Many thanks to the acquisition and recruitment team: Marisa Riley, Jack Keefe, Nick DeLeo, Raphael Gerraty, Elliott Yodh, and Rosetta Chiavacci. Thanks to Ewald Moser for discussion.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2013.06.045">doi:10.1016/j.neuroimage.2013.06.045</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23792981">pmid:23792981</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3874413/">pmcid:PMC3874413</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/qp37br62ojhdlbj56q22ox7koe">fatcat:qp37br62ojhdlbj56q22ox7koe</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200208093710/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3874413&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/ef/b5/efb5a4083c700f1980f2f11c0feca9b6f5fa1a7b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2013.06.045"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874413" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Heritable cognitive and psychopathology factors in youth are predicted by brain fronto-temporal white matter pathway [article]

Dag Alnaes, Tobias Kaufmann, Nhat Trung Doan, Aldo Cordova-Palomera, Yunpeng Wang, Francesco Bettella, Torgeir Moberget, Ole A. Andreassen, Lars T. Westlye
<span title="2017-08-03">2017</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Here, we employed data driven multivariate approaches to derive both general cognitive and psychopathology factors as well as brain phenotypes in children and adolescents in the publicly available PNC  ...  We identified a distinct brain white matter pattern which proved central for prediction of heritable cognition and psychopathology scores, highlighting the importance of fronto-temporal connections for  ...  Sample and exclusion criteria: The analysis was based on the publicly available Philadelphia Neurodevelopmental Cohort 7, 15 (PNC, access obtained with permission #8642, project title: Neurodevelopmental  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/172080">doi:10.1101/172080</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/3udopwnaj5hclpgowvvsofzqnq">fatcat:3udopwnaj5hclpgowvvsofzqnq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190502202543/https://www.biorxiv.org/content/biorxiv/early/2017/08/03/172080.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/fb/eb/fbeb2897583687c402528d06e14263d29e7c17e3.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/172080"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>
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