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Vascular stasis, intestinal hemorrhage, and heightened vascular permeability complicate acute portal hypertension in cd39-null mice
2009
American Journal of Physiology - Gastrointestinal and Liver Physiology
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Vascular stasis, intestinal hemorrhage, and heightened vascular permeability complicate acute portal hypertension in cd39-null mice. ...
ACKNOWLEDGMENTS The authors thank Dr. Juan G. Abraldes for insightful comments.
GRANTS ...
This relative failure to generate adenosine within the vasculature results in decreased type-1 purinergic/adenosine receptor activation and disordered vascular inflammatory responses in the Cd39-null mouse ...
doi:10.1152/ajpgi.90703.2008
pmid:19520738
pmcid:PMC2724088
fatcat:w6hgygd4gzd5jbrb6jsptmpp7e
Smad3 Deficiency Counteracts Hepatocyte Apoptosis and Portal Fibrogenesis Induced By Bile Duct Ligation
2014
Journal of Liver
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Results: Here we found that mice lacking Smad3 are protected against cholestatic liver injury induced by BDL as evidenced by the absence of hepatocyte apoptosis and portal fibroproliferative responses, ...
Smad3-null mice are also shown to reverse the hepatic TGF-β1 upregulation after BDL. ...
Acknowledgements We are very grateful to the late Dr. Anita B. Roberts for her suggestions and encouragement. We also thank Mario Anzano for his help with the Smad3-null mice. ...
doi:10.4172/2167-0889.1000145
fatcat:5hrzs5htwjftpakbz2r2nr3c4m
Extracting Duplicate Georeferences from Herbarium Specimen Data
[article]
2021
Zenodo
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portal). ...
The user must then clean the output file so it results in one row per specimen record. ...
duplicates, one record in the target dataset may result in several records/rows in the output dataset. ...
doi:10.5281/zenodo.4637000
fatcat:6myagvh2azbn5mp5dhuy3gdpe4
Bile duct proliferation in liver-specificJag1conditional knockout mice: Effects of gene dosage
2007
Hepatology
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When Jag1 conditional mice were crossed with mice carrying the Jag1 null allele, the adult progeny exhibited striking bile duct proliferation. ...
Conclusion: These results indicate that Notch signaling in the liver is sensitive to Jag1 gene dosage and suggest a role for the Notch pathway in postnatal growth and morphogenesis of bile ducts. ...
in the Jag1 conditional/null mice might be a result of decreased overall Notch signaling. ...
doi:10.1002/hep.21460
pmid:17366661
fatcat:rjkn2nrdgrhztjks5ugnx3ho4m
Page 603 of Annals of Internal Medicine Vol. 55, Issue 4
[page]
1961
Annals of Internal Medicine
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.: Assessment of the results of surgical treatment in portal hypertension.
Gastroenterology 38: 142, 1960.
We tcu, C. S., Ramos, A. ...
.: Results of porta caval shunts in the treatment of portal hyper tension. Surgery 41: 756, 1957.
Fercuson, D. J.: Experience with surgery for portal hypertension. J. Lancet 77: 426, 1957 ...
Tryptophan Residues in the Portal Protein of Herpes Simplex Virus 1 Critical to the Interaction with Scaffold Proteins and Incorporation of the Portal into Capsids
2009
Journal of Virology
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of the portal protein precluded this coimmunoprecipitation. ...
In contrast, the W27A mutation precluded portal-scaffold interactions in infected cell lysates, reduced the solubility of pU L 6, decreased incorporation of the portal into capsids, and abrogated viral-DNA ...
ACKNOWLEDGMENTS These studies were supported by R01 grant GM50740 from the National Institutes of Health. We thank Elizabeth Wills for reading the manuscript. ...
doi:10.1128/jvi.01463-09
pmid:19740984
pmcid:PMC2772705
fatcat:ooqtsqorbfbshfouxfsog2covi
Distinct roles of ecto-nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) in liver regeneration and fibrosis
2017
Purinergic Signalling Purinergic Signalling
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Liver regeneration after partial hepatectomy is not substantively impaired in global Entpd2 null mice. NTPDase2 protects from liver fibrosis resulting from hepatocellular injury induced by CCl 4 . ...
In injured livers, NTPDase2 expression extends from the portal areas to fibrotic septae in pan-lobular (CCl 4 -induced) liver fibrosis; the same pattern was observed, albeit to a lesser extent in biliary-type ...
This ecto-enzyme is primarily an ATPase with minimal ADPase activity, which results in the accumulation of ADP in the extracellular milieu [10] . ...
doi:10.1007/s11302-017-9590-3
pmid:29134411
pmcid:PMC5842151
fatcat:gryuud45kzg3tpixoaw7gc4wpy
The role of sodium-coupled glucose co-transporter 3 in the satiety effect of portal glucose sensing
2013
Molecular Metabolism
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From these results we propose a finely tuned dual mechanism for portal glucose sensing that responds to different physiological conditions. ...
A similar response of Trpm5-null mice and portal infusions of sweeteners also excluded sugar taste receptors. ...
Then we used Trpm5-null mice in the same paradigm as GLUT2-null mice. ...
doi:10.1016/j.molmet.2012.11.003
pmid:24024129
pmcid:PMC3757661
fatcat:qk5jr6k7rfedjl47mead7crpce
Metrics for Outpatient Portal Use Based on Log File Analysis: Algorithm Development
2020
Journal of Medical Internet Research
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facilitate the adoption of behavioral metrics that enable the measurement of patient engagement based on the outpatient portal use. ...
Of the 2607 patients in our sample, 2511 were active users of the patients portal where the median number of sessions was 94 (IQR 207). ...
Acknowledgments This work was supported by the Agency for Healthcare Research and Quality grants R01 HS024091-01, R21 HS024349-01, and P30-HS024379. ...
doi:10.2196/16849
pmid:32530435
pmcid:PMC7320309
fatcat:ytk4mhi4mvfezdcjum4xmcisau
Development of the web portal for research support in the area of electrical impedance tomography
2019
Eastern-European Journal of Enterprise Technologies
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Acknowledgements The study is carried out as part of the federal target program "Research and Development in Priority Directions for the Development of the Russian Science and Technology Complex for 2014 ...
-2020", with financial support from the Ministry of Science and Higher Education (agreement No. 05.607.21.0305). ...
Discussion of experimental results of EIT web portal research The obtained timing results of the web portal work for various matrix dimensions, presented in Table 6 , allow to calculate the conduction ...
doi:10.15587/1729-4061.2019.184318
fatcat:uhggq4iwyvh53jlfcqr6k7fr4u
Peripheral activation of the Y2-receptor promotes secretion of GLP-1 and improves glucose tolerance
2013
Molecular Metabolism
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ACKNOWLEDGMENTS This work was funded by the Rosetrees Trust. K.C., E.I.E., A.I.C., and D.J.W were funded by the MRC. K.C. researched data and wrote the article. ...
., F.A researched data and reviewed the article. D.J.W. researched data, contributed to discussion, and reviewed the article. R.L.B. researched data and wrote the article. ...
The common bile duct was clamped and a Liberase solution (Roche, UK) solution was injected into the pancreatic duct resulting in pancreatic disruption. ...
doi:10.1016/j.molmet.2013.03.001
pmid:24049729
pmcid:PMC3773824
fatcat:jrltyxpt2ngcrk3g2ga4nd6jte
Cryo-electron tomography of the herpesvirus procapsid reveals interactions of the portal with the scaffold and a shift on maturation
[article]
2020
bioRxiv
pre-print
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The portal is embedded in the underlying scaffold, consistent with assembly initiating on a portal-scaffold complex. ...
The portal is located on the interior surface with its narrower end facing outwards in contact with the capsid shell. ...
Tomograms were 410 binned 2-fold, resulting in a final pixel size of 3.66 Å for UL25-null A-capsids and 3.61 Å for 411 procapsids. ...
doi:10.1101/2020.09.30.320457
fatcat:xyziyv4pmzcaxkbd3zo6fvb3he
Cholesterol Feeding Prevents Hepatic Accumulation of Bile Acids in Cholic Acid-Fed Farnesoid X Receptor (FXR)-Null Mice: FXR-Independent Suppression of Intestinal Bile Acid Absorption
2008
Drug Metabolism And Disposition
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Fecal bile acid excretion was also increased in Fxr-null mice fed the CA؉Chol versus CA diet. ...
Cholic acid (CA) feeding of farnesoid X receptor (Fxr)-null mice results in markedly elevated hepatic bile acid levels and liver injury. ...
The portal blood bile acid concentration was approximately 11-fold higher in Fxr-null mice fed the CA diet compared with Fxr-null mice fed the control diet (Fig. 4) . ...
doi:10.1124/dmd.108.022590
pmid:18988759
pmcid:PMC2680521
fatcat:pljnwn4fkne7jkjmqgj6ec3mhy
Page 33 of None Vol. 12, Issue 1
[page]
1985
None
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RESULTS
The pattern of variation of plasma glucose, IRI, IRG, and SRIF across the clock time in portal blood of four 1
6s PORTAL n=2
1600r gs 1400 1
1
oS 8888 8s 88 8
E37
normal dogs, sampled every 7.5 ...
A two-factor analysis of variance was then performed on the obtained components using the F dis- tribution and rejecting the null hypothesis of equivalent mean frequencies among the two classifications ...
Portal m-Da'wah using Wireless Application Protocol
2013
IJID (International Journal on Informatics for Development)
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The test results show that the application meets the functionality requirements and is suitable for use. ...
The study method used in this study is system development, which is an experiment for the design of the m-da'wah portal that can be accessed via a cellphone or PDA. ...
The results will be displayed on the screen of the device being used.
D. ...
doi:10.14421/ijid.2013.02105
doaj:54ef23c74e0e4e868e0e316675babcb5
fatcat:s7zwkqanubggfp4ahgukulzqmi
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