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Human Skin and Hair Xenografted on SCID Mouse. Usefulness as an in vivo Experimental Model
ヒトの皮膚・頭髪研究へのSCIDマウスの有用性
1997
Proceedings of The Japanese Society of Animal Models for Human Diseases
ヒトの皮膚・頭髪研究へのSCIDマウスの有用性
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To develop new in vivo study system of human skin and hair, our research group has tried to produce hu-skin/SCID mice model, that is, mice xenografted with human skin or hair suitable for in vivo experiments ...
An isolated human hair follicle obtained by dissection of scalp skin was successfully transplanted onto SCID mice and used to identify localization of stem cells of hair follicles. ...
doi:10.1538/expanim1992.13.19
fatcat:vlxm4f3izjfltjjagpsq74idcq
The Abnormality of Vestibular Hair Cells and the Gene Transduction in Animal Model of Human Genetic Inner Ear Disease-Study of Vestibular Hair Cell Pathology in Shaker-2 Mouse and Waltzing Guinea Pig-
遺伝性内耳障害モデルにおける前庭形態異常と遺伝子導入の試み―shaker‐2マウス,waltzing guinea Pigの検討から―
2004
Equilibrium Research
遺伝性内耳障害モデルにおける前庭形態異常と遺伝子導入の試み―shaker‐2マウス,waltzing guinea Pigの検討から―
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We reviewed the hair cell pathology of genetic hearing loss and circling behavior and discussed possibility of gene therapy in human genetic inner ear disease through genetic inner ear disease animal models ...
Furthermore, we tested the possibility of gene transudation in shaker-2 mice, the model of DFNB3, i.e. human deafness, in order to treat the hair cell pathology including cytocaud. ...
文 献 1) Ikezono T, Omori A, Ichinose S, et al: Identification of the protein product of the Coch gene (hereditary deafness gene) as the major com-ventional myosins and the genetics of hearing loss. ...
doi:10.3757/jser.63.81
fatcat:emk3k5j2vfd35gn6otog3wcnje
Urate Oxidase Activity and Copper Content in the Liver of Macular Mutant Mouse, a Model Animal for Human Congenital Copper Deficiency, Menkes' Kinky Hair Disease
1991
Journal of Nutritional Science and Vitaminology
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In spite of similarities in biochemical and histological features between human disease and model mice, there is a critical difference between the two. ...
In human disease, many trials to improve the symptoms and save the life have been unsuc cessful (29, 30) , whereas the symptoms of the model mice can be significantly improved and the life span can be ...
doi:10.3177/jnsv.37.601
fatcat:u5l6zd47ybccvotulewsekq6cq
Positional Cloning of the shaker-1 Gene : A Myosin VII Involved in Sensory Hair Cell Development and Function
1996
Proceedings of The Japanese Society of Animal Models for Human Diseases
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The other shaker=l mutations are all more severe in their effects on the cochlea and most show no signs of any cochlear responses at any stage of development. ...
Finally, we have also shown that the human homologue of shaker=l is the gene affected in Usher syndrome type lb (Weil et al.: Nature, 374 60-61 (1995) ) in which progressive retinitis pigmentosa accompanies ...
doi:10.1538/expanim1992.12.2
fatcat:uffgbyq7kbbfpkxlklodsy47qu
SGK3はマウス毛形成および毛周期の重要な制御因子である
SGK3 Plays Critical Roles in Murine Hair Follicle Morphogenesis and Hair Cycle Regulation
2006
Proceedings of The Japanese Society of Animal Models for Human Diseases
SGK3 Plays Critical Roles in Murine Hair Follicle Morphogenesis and Hair Cycle Regulation
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SGK3 Plays Critical Roles in Murine Hair Follicle Morphogenesis and Hair Cycle Regulation Taro OKADA1,6), Kentaro MASUJIN2), Yoshiyuki ISHII3), Akira YASOSHIMAI), Junichiro MATSUDA4), Atsuo OGURA5), ...
The hair follicle length, which corresponds to the length from the base of the hair follicle bulb to the surface of the epidermis, represents the hair follicle cycling
tological study on the skin and ...
The hair follicle length, which corresponds to the length from the base of the hair follicle bulb to the surface of the epidermis, represents the hair follicle cycling pattern. ...
doi:10.1538/expanim1992.22.12
fatcat:lzabunfvyvavfo6tvhn67vacpq
Real Time Physical Force-Driven Hair Animation
2018
Zenodo
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This paper proposed physical forces of gravity and wind to be applied into hair animation in real time based on wisp model and verlet integration technique. ...
The current technique still can be improved by apply tessellation technique to reduce excessive use of resources and not only straight-type hair model such as curly or frizzy. ...
The authors, therefore, gratefully acknowledge the DSR technical and financial support. ...
doi:10.5281/zenodo.2550644
fatcat:horwqc746fffxdi6xtzrv3rvla
Evaluation of Animal Models Suitable for Hair Research and Regeneration
[chapter]
2018
Experimental Animal Models of Human Diseases - An Effective Therapeutic Strategy
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The main reason for hair research on animal models relies on the similarities between human and animal skin biology. ...
By using proper and well thought-out animal models, we aim to refine our knowledge on human hair diseases and hair regrowth. ...
Hair regrowth studies in vivo
The need of animal models Animals and humans are remarkably similar at physiological and anatomical levels. ...
doi:10.5772/intechopen.69698
fatcat:qhjcfn4a4rft7ifhz5qhz7xw5y
Performance Analysis of Virtual Human Bodies with Clothing and Hair from Images to Animation
2018
International Journal of Advanced Research in Computer Science and Software Engineering
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Virtual human bodies, clothing, and hair are widely used in a number of scenarios such as 3D animated movies, gaming, and online fashion. ...
Machine learning can be used to construct data-driven 3D human bodies, clothing, and hair. ...
Besides human body modeling, how to realistically represent clothing and hair is also on the top of the research agenda. ...
doi:10.23956/ijarcsse.v8i6.723
fatcat:rz3k6icm7fepdd5ztpnsw53faa
A Simple Physics Model to Animate Human Hair Modeled in 2D Strips in Real Time
[chapter]
2001
Eurographics
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A major difficulty in animating human hair results from the large number of individual hair strands in a hairstyle. ...
This paper presents a simple Physics model to animate human hair modeled in 2D strips in real time. ...
Introduction Hair modeling and animation are very challenging tasks in human animation due to the presences of a large number of hair, the complex interaction of light and shadow amongst them, and the ...
doi:10.1007/978-3-7091-6240-8_12
fatcat:n6l4hfjhencqpnyf54vt46hn3y
Evaluation of Animal Models for the Hair-Inducing Capacity of Cultured Human Dermal Papilla Cells
2009
Cells Tissues Organs
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Conclusions: Although there is no significant difference in hair induction rate, the sandwich model using cultured hDPCs and the rat sole skin is more feasible than the chamber model using human cultured ...
Results: Folliculoneogenesis was detected in both chamber and sandwich models, although the induction rate and maturity of the hair follicles varied among cell combination subgroups in each model. ...
Acknowledgement This work was supported by a grant from the Japanese Ministry of Education, Culture, Sports, Science and Technology (contact grant No. B2-17390474). ...
doi:10.1159/000178021
pmid:19033718
fatcat:3bu3ywn7wjhnhmctgpvehpz56u
An Integrated System for Modeling, Animating and Rendering Hair
1993
Computer graphics forum (Print)
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We present how hair styles may be designed with our HairStyler module. Then we survey the animation model and emphasize a method of collision processing. ...
There are basically four problems to solve in order to produce realistic animated synthetic actors with hair: hair modeling and creation, hair motion, collision detection and hair rendering. ...
Acknowledgments The authors would like to thank Dr. Geoff Wyvill for his useful remarks and discussion in hair rendering and hair interface problems. ...
doi:10.1111/1467-8659.1230211
fatcat:hgpz2mhp45emjkdewxq2fbbvp4
Research Problems for Creating Digital Actors
[article]
2003
Eurographics State of the Art Reports
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In particular, our research has been focused on components such as facial animation, hair animation, clothing animation, and body animation, which are crucial to the successful realization of digital actors ...
This article summarizes the results of our research on those topics, reviews other approaches that have been taken in digital actor research, and outlines the challenges that must be overcome in this area ...
This work was also partially supported by Automation and Systems Research Institute at Seoul National University, the Brain Korea 21 Project, and the Overhead Research Fund of Seoul National University ...
doi:10.2312/egst.20031088
fatcat:ldk5qnmbv5crbge5te55pec3uq
3D skin models in domestic animals
2021
Veterinary Research
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The development of these models benefited from the societal pressure to reduce animal experiments. ...
Next, we describe the different 3D human skin models and their main applications. Finally, we review the available models for domestic animals and discuss the current and potential applications. ...
Danielle Dhouailly for her expert comments on the manuscript.
Authors' contributions LS and CD and wrote the manuscript. Both authors read and approved the final manuscript. ...
doi:10.1186/s13567-020-00888-5
pmid:33588939
fatcat:eijlaz7smbeifivnddj2s2l74m
Virtual humans: thirty years of research, what next?
2005
The Visual Computer
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To give a level of believable behavior, challenges are laid on generating on the fly flexible motion and complex behaviours of Virtual Humans inside their environments using a realistic perception of the ...
At first, the issues of creating virtual humans with better skeleton and realistic deformable bodies are illustrated. ...
Hair animation One of the many challenges in simulating believable virtual humans and animals has been to produce realistic looking hair. ...
doi:10.1007/s00371-005-0363-6
fatcat:66uenhkqv5citi5jss22wqxk7e
Animal models of vitiligo: Matching the model to the question
2014
Zhōnghuá Pífūkē Yīxué Zázhì
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Because of the complex pathogenesis of vitiligo, it is unlikely that any one single animal model will adequately reflect all factors implicated in the initiation, progression, and maintenance of the disease ...
In this paper, we describe some of the available animal models that have been developed to study vitiligo. ...
One key difference is the distribution of melanocytes in the skin. Human melanocytes reside in the hair follicles and in the epidermis of hair-bearing skin. ...
doi:10.1016/j.dsi.2014.09.008
fatcat:3koxosmb65cu3git2jh42tjsbq
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