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The European Nucleotide Archive

R. Leinonen, R. Akhtar, E. Birney, L. Bower, A. Cerdeno-Tarraga, Y. Cheng, I. Cleland, N. Faruque, N. Goodgame, R. Gibson, G. Hoad, M. Jang (+9 others)
2010 Nucleic Acids Research  
The European Nucleotide Archive (ENA; http://www .ebi.ac.uk/ena) is Europe's primary nucleotidesequence repository.  ...  The objective of ENA is to support and promote the use of nucleotide sequencing as an experimental research platform by providing data submission, archive, search and download services.  ...  THE EUROPEAN NUCLEOTIDE ARCHIVE The European Nucleotide Archive (ENA) operates as a public archive for nucleotide sequence data.  ... 
doi:10.1093/nar/gkq967 pmid:20972220 pmcid:PMC3013801 fatcat:pla5imfirvedhhclz3qcbuvgge

The European Nucleotide Archive in 2018

Peter W Harrison, Blaise Alako, Clara Amid, Ana Cerdeño-Tárraga, Iain Cleland, Sam Holt, Abdulrahman Hussein, Suran Jayathilaka, Simon Kay, Thomas Keane, Rasko Leinonen, Xin Liu (+12 others)
2018 Nucleic Acids Research  
The European Nucleotide Archive (ENA; https://www. ebi.ac.uk/ena), provided from EMBL-EBI, has for more than three decades been responsible for archiving the world's public sequencing data and presenting  ...  this important resource to the scientific community to support and accelerate the global research effort.  ...  INTRODUCTION For over a third of a century, the European Nucleotide Archive (ENA) has served as a cornerstone of the world's bioinformatics infrastructure.  ... 
doi:10.1093/nar/gky1078 pmid:30395270 fatcat:kmr4vyojundfzabhv3dwdciamu

The European Nucleotide Archive in 2017

Nicole Silvester, Blaise Alako, Clara Amid, Ana Cerdeño-Tarrága, Laura Clarke, Iain Cleland, Peter W Harrison, Suran Jayathilaka, Simon Kay, Thomas Keane, Rasko Leinonen, Xin Liu (+11 others)
2017 Nucleic Acids Research  
For 35 years the European Nucleotide Archive (ENA; https://www.ebi.ac.uk/ena) has been responsible for making the world's public sequencing data available to the scientific community.  ...  Advances in sequencing technology have driven exponential growth in the volume of data to be processed and stored and a substantial broadening of the user community.  ...  European Nucleotide Archive (ENA), maintained at the EMBL European Bioinformatics Institute (EMBL-EBI).  ... 
doi:10.1093/nar/gkx1125 pmid:29140475 pmcid:PMC5753375 fatcat:s2q7ka7s5nbufi7gnztodzyzym

The European Nucleotide Archive in 2019

2019 Nucleic Acids Research  
The European Nucleotide Archive (ENA, https://www.ebi.ac.uk/ena) at the European Molecular Biology Laboratory's European Bioinformatics Institute provides open and freely available data deposition and  ...  access services across the spectrum of nucleotide sequence data types.  ...  have led to a broad range of nucleotide sequences that build the content of today's European Nucleotide Archive (ENA).  ... 
doi:10.1093/nar/gkz1063 pmid:31722421 pmcid:PMC7145635 fatcat:aorxf6izbvbkhb7jwbjawugaci

Facing growth in the European Nucleotide Archive

Guy Cochrane, Blaise Alako, Clara Amid, Lawrence Bower, Ana Cerdeño-Tárraga, Iain Cleland, Richard Gibson, Neil Goodgame, Mikyung Jang, Simon Kay, Rasko Leinonen, Xiu Lin (+17 others)
2012 Nucleic Acids Research  
The European Nucleotide Archive (ENA; http://www. ebi.ac.uk/ena/) collects, maintains and presents comprehensive nucleic acid sequence and related information as part of the permanent public scientific  ...  First, we describe the ENA data warehouse, a resource for which we provide a programmatic entry point to integrated content across the breadth of ENA.  ...  INTRODUCTION The European Nucleotide Archive (ENA; http://www.ebi. ac.uk/ena) has for the last 30 years captured, organized and presented the world's public domain output of sequence information.  ... 
doi:10.1093/nar/gks1175 pmid:23203883 pmcid:PMC3531187 fatcat:fdf5xomwnbdz3kiv3ngyh44dty

Assembly information services in the European Nucleotide Archive

Nima Pakseresht, Blaise Alako, Clara Amid, Ana Cerdeño-Tárraga, Iain Cleland, Richard Gibson, Neil Goodgame, Tamer Gur, Mikyung Jang, Simon Kay, Rasko Leinonen, Weizhong Li (+18 others)
2013 Nucleic Acids Research  
The European Nucleotide Archive (ENA; http://www. ebi.ac.uk/ena) is a repository for the world public domain nucleotide sequence data output.  ...  components of the submission service.  ...  INTRODUCTION The European Nucleotide Archive (ENA) is the European resource in which the world's public domain sequencing data are maintained.  ... 
doi:10.1093/nar/gkt1082 pmid:24214989 pmcid:PMC3965037 fatcat:sddhoeztgfdkhbyx3zrms3ajza

Improvements to services at the European Nucleotide Archive

Rasko Leinonen, Ruth Akhtar, Ewan Birney, James Bonfield, Lawrence Bower, Matt Corbett, Ying Cheng, Fehmi Demiralp, Nadeem Faruque, Neil Goodgame, Richard Gibson, Gemma Hoad (+17 others)
2009 Nucleic Acids Research  
The European Nucleotide Archive (ENA; http://www .ebi.ac.uk/ena) is Europe's primary nucleotide sequence archival resource, safeguarding open nucleotide data access, engaging in worldwide  ...  nucleotide sequence archive.  ...  The principal policy of INSDC is to provide free and unrestricted permanent access to all archived nucleotide data.  ... 
doi:10.1093/nar/gkp998 pmid:19906712 pmcid:PMC2808951 fatcat:7hx2okpxtbdcvpeoabj2q5emhe

Petabyte-scale innovations at the European Nucleotide Archive

G. Cochrane, R. Akhtar, J. Bonfield, L. Bower, F. Demiralp, N. Faruque, R. Gibson, G. Hoad, T. Hubbard, C. Hunter, M. Jang, S. Juhos (+15 others)
2009 Nucleic Acids Research  
The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/embl), comprising the EMBL Nucleotide Sequence Database and the Ensembl Trace Archive, has identified challenges in the storage, movement, analysis  ...  Dramatic increases in the throughput of nucleotide sequencing machines, and the promise of ever greater performance, have thrust bioinformatics into the era of petabyte-scale data sets.  ...  The European Nucleotide Archive (ENA), the collective name for nucleotide sequencing information archiving and presentation services at EMBL-EBI, comprising the EMBL Nucleotide Sequence Database and the  ... 
doi:10.1093/nar/gkn765 pmid:18978013 pmcid:PMC2686451 fatcat:xzwl3cvkjnarxbbbowzbnhazpi

Major submissions tool developments at the European nucleotide archive

C. Amid, E. Birney, L. Bower, A. Cerdeno-Tarraga, Y. Cheng, I. Cleland, N. Faruque, R. Gibson, N. Goodgame, C. Hunter, M. Jang, R. Leinonen (+15 others)
2011 Nucleic Acids Research  
The European Nucleotide Archive (ENA; http://www .ebi.ac.uk/ena), Europe's primary nucleotide sequence resource, captures and presents globally comprehensive nucleic acid sequence and associated information  ...  of the methodology.  ...  INTRODUCTION The European Nucleotide Archive (ENA) is maintained and developed at the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI) and serves as Europe's primary  ... 
doi:10.1093/nar/gkr946 pmid:22080548 pmcid:PMC3245037 fatcat:qxbkwotuvfglhgef5ajiqczieq

Biocuration of functional annotation at the European nucleotide archive

Richard Gibson, Blaise Alako, Clara Amid, Ana Cerdeño-Tárraga, Iain Cleland, Neil Goodgame, Petra ten Hoopen, Suran Jayathilaka, Simon Kay, Rasko Leinonen, Xin Liu, Swapna Pallreddy (+9 others)
2015 Nucleic Acids Research  
The European Nucleotide Archive (ENA; http://www. ebi.ac.uk/ena) is a repository for the submission, maintenance and presentation of nucleotide sequence data and related sample and experimental information  ...  The importance of functional annotation, how it can be submitted and the shifting role of the biocurator in the context of increasing volumes of data are all discussed.  ...  INTRODUCTION The European Nucleotide Archive (ENA), maintained at the European Bioinformatics Institute (EMBL-EBI) in Hinxton, UK, is a permanent nucleotide sequencing repository which hosts the world's  ... 
doi:10.1093/nar/gkv1311 pmid:26615190 pmcid:PMC4702917 fatcat:wqzh2jm6srhjrkhmp7vn3fd7za

Content discovery and retrieval services at the European Nucleotide Archive

Nicole Silvester, Blaise Alako, Clara Amid, Ana Cerdeño-Tárraga, Iain Cleland, Richard Gibson, Neil Goodgame, Petra ten Hoopen, Simon Kay, Rasko Leinonen, Weizhong Li, Xin Liu (+12 others)
2014 Nucleic Acids Research  
The European Nucleotide Archive (ENA; http://www. ebi.ac.uk/ena) is Europe's primary resource for nucleotide sequence information.  ...  With the growing volume and diversity of public sequencing data comes the need for increased sophistication in data organisation, presentation and search services so as to maximise its discoverability  ...  INTRODUCTION For 30 years, the European Nucleotide Archive (ENA) has been capturing, organizing and presenting openly the world's public domain sequencing data.  ... 
doi:10.1093/nar/gku1129 pmid:25404130 pmcid:PMC4383942 fatcat:7em6pbntxjbqdcs5xprtjkfwza

A SARS-CoV-2 sequence submission tool for the European Nucleotide Archive

Miguel Roncoroni, Bert Droesbeke, Ignacio Eguinoa, Kim De Ruyck, Flora D'Anna, Dilmurat Yusuf, Björn Grüning, Rolf Backofen, Frederik Coppens
2021 Bioinformatics  
The European Nucleotide Archive (ENA) is the European recommended open repository for genetic sequences. In this work, we present a tool for submitting raw sequencing reads of SARS-CoV-2 to ENA.  ...  Many aspects of the global response to the COVID-19 pandemic are enabled by the fast and open publication of SARS-CoV-2 genetic sequence data.  ...  In the COVID-19 Data Portal (www.covid19dataportal.org), the repository for SARS-CoV-2 nucleotide sequence data is the European Nucleotide Archive (ENA).  ... 
doi:10.1093/bioinformatics/btab421 pmid:34096994 fatcat:ube7ho4gs5baloejmvbykk4cee

C# desktop application with connection to the European Nucleotide Archive for fast identification of tandem repeats

Done Stojanov
2017 Advanced Studies in Biology  
This application works both with randomly provided content and real samples retrieved from the European Nucleotide Archive.  ...  In spite of tandem's structure, details regarding the total number of tracked tandems, their range within the sample, the structure of the pattern sequence and the running time of the application are also  ...  This study was supported by the research project Development of Secure and Reliable Techniques for Data Communication, funded by ,,Goce Delcev" University in Stip.  ... 
doi:10.12988/asb.2017.7926 fatcat:wn5easr3kbhgpdyli5lfhblkda

Molecular physiology and pathology of the nucleotide sugar transporter family (SLC35)

Nobuhiro Ishida, Masao Kawakita
2004 Pflügers Archiv: European Journal of Physiology  
The family members so far characterized encode nucleotide sugar transporters localizing at the Golgi apparatus and/or the endoplasmic reticulum (ER).  ...  These transporters transport nucleotide sugars pooled in the cytosol into the lumen of these organelles, where most glycoconjugate synthesis occurs.  ...  Fig. 1 A phylogenetic tree of the SLC35 family of human nucleotide sugar transporters.  ... 
doi:10.1007/s00424-003-1093-0 pmid:12759756 fatcat:2i3subgnlvfvnebncn2qry6bmi

Modulation of the hepatocyte rough endoplasmic reticulum single chloride channel by nucleotide–Mg2+ interaction

M. Ashrafpour, J. Fahanik Babaei, R. Saghiri, H. Sepehri, H. Sharifi
2012 Pflügers Archiv: European Journal of Physiology  
The effect of nucleotides on single chloride channels derived from rat hepatocyte rough endoplasmic reticulum vesicles incorporated into bilayer lipid membrane was investigated.  ...  the Po and unitary current amplitude.  ...  Acknowledgments This work was supported by a grant from the Cellular and Molecular Research Center of Babol University of Medical Sciences in collaboration with Neuroscience Research Center of Shahid Beheshti  ... 
doi:10.1007/s00424-012-1121-z pmid:22684478 fatcat:ipc5ogs3bfaovlcjusdmcvkub4
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