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The Crossover Closure and Partial Match Detection [chapter]

Fernando Esponda, Stephanie Forrest, Paul Helman
2003 Lecture Notes in Computer Science  
The crossover closure generation rule characterizes the generalization achieved by artificial immune systems using partial match detection.  ...  The paper reviews earlier results and extends the previously introduced notion of crossover closure to encompass additional match rules.  ...  Projects Agency (grant AGR F30602-00-2-0584), the Intel Corporation, and the Santa Fe Institute.  ... 
doi:10.1007/978-3-540-45192-1_24 fatcat:wm4vpckqd5avjhlfmbpa33r47e

A Formal Framework for Positive and Negative Detection Schemes

F. Esponda, S. Forrest, P. Helman
2004 IEEE Transactions on Systems Man and Cybernetics Part B (Cybernetics)  
A new match rule is introduced, called -chunks, and the generalizations induced by different partial matching rules are characterized in terms of the crossover closure.  ...  Partial matching rules generalize the set of allowable (or unallowable) patterns, and the choice of matching rule affects the tradeoff between positive and negative detection.  ...  ACKNOWLEDGMENT The authors would also like to thank J. Holland, A. Tyrrell, W. Langdon, and the anonymous reviewers, who's comments greatly improved the presentation of this work.  ... 
doi:10.1109/tsmcb.2003.817026 pmid:15369078 fatcat:4xuqubnivnfp3ld2vqadzartca

Negative representations of information

Fernando Esponda, Stephanie Forrest, Paul Helman
2009 International Journal of Information Security  
I would like to thank my Dad, Mom and Sister; Mom, Dad and Sister; Sister, Mom and Dad; Mom, Sister and Dad; Dad, Sister and Mom; Sister, Dad and Mom in no particular order and with all my heart.  ...  The join operator and the crossover closure are closely related under some partial match rules, leading to the belief that the crossover closure may be a useful characterization for many practical data  ...  The crossover closure is introduced, in Section 3.3, as a generalization construct that can be realized using the match rule and the detection schemes described in the previous sections.  ... 
doi:10.1007/s10207-009-0078-1 fatcat:yg4ss2ul7rbvdewypzrxmvpcni

Revisiting Negative Selection Algorithms

Zhou Ji, Dipankar Dasgupta
2007 Evolutionary Computation  
This paper reviews the progress of negative selection algorithms, an anomaly/change detection approach in Artificial Immune Systems (AIS).  ...  There exist various elements in this method, including data representation, coverage estimate, affinity measure, and matching rules, which are discussed for different variations.  ...  Three generation rules are presented: Hamming radius, crossover closure, and n-gram.  ... 
doi:10.1162/evco.2007.15.2.223 pmid:17535140 fatcat:k36m7vvshrbn3amf26uiqbem3a

Lenalidomide and high-dose dexamethasone compared with dexamethasone as initial therapy for multiple myeloma: a randomized Southwest Oncology Group trial (S0232)

J. A. Zonder, J. Crowley, M. A. Hussein, V. Bolejack, D. F. Moore, B. F. Whittenberger, M. H. Abidi, B. G. M. Durie, B. Barlogie
2010 Blood  
One-year progression-free survival, overall response rate, and very good partial response rate were superior with LEN-DEX (78% vs 52%, P ‫؍‬ .002; 78% vs 48%, P < .001; 63% vs 16%, P < .001), whereas 1  ...  Monthly maintenance used DEX 40 mg/day on days 1 to 4 and 15 to 18 along with LEN 25 mg/day for 21 days or PLC. Crossover from PLC-DEX to LEN-DEX was encouraged on progression.  ...  Acknowledgments The authors thank Marjorie A. Godfrey  ... 
doi:10.1182/blood-2010-08-303487 pmid:20876454 pmcid:PMC3031379 fatcat:lm23dfwuzrda5o5ih5znewvzce

Multi-Objective Optimization of Loop Closure Detection Parameters for Indoor 2D Simultaneous Localization and Mapping

Dongxiao Han, Yuwen Li, Tao Song, Zhenyang Liu
2020 Sensors  
Aiming at addressing the issues related to the tuning of loop closure detection parameters for indoor 2D graph-based simultaneous localization and mapping (SLAM), this article proposes a multi-objective  ...  Only loop closure detection parameters have been considered in this article, but the proposed evaluation metrics and optimization method have potential applications in the automatic tuning of other SLAM  ...  Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/s20071906 pmid:32235456 fatcat:r5b2n5sl5zfajmswlgvcaay7bu

Phosphoregulation of HORMA domain protein HIM-3 promotes asymmetric synaptonemal complex disassembly in meiotic prophase in Caenorhabditis elegans

Aya Sato-Carlton, Chihiro Nakamura-Tabuchi, Xuan Li, Hendrik Boog, Madison K. Lehmer, Scott C. Rosenberg, Consuelo Barroso, Enrique Martinez-Perez, Kevin D. Corbett, Peter Mark Carlton, Sarit Smolikove
2020 PLoS Genetics  
Here, we investigate the meiotic axis HORMA-domain protein HIM-3 and show that it becomes phosphorylated at its C-terminus, within the conserved "closure motif" region bound by the related HORMA-domain  ...  designation of crossover sites.  ...  Kawahara and K. Oegema for antibodies and the past and current members of the Carlton lab for technical assistance.  ... 
doi:10.1371/journal.pgen.1008968 pmid:33175901 fatcat:tsupfzwokfe5lkpnn6j67d4zpe

Genetic approaches to learning recursive relations [chapter]

P. A. Whigham, R. I. McKay
1995 Lecture Notes in Computer Science  
Operations from the field of Inductive Logic Programming, such as the V and W operators, are shown to have analogies with GP crossover but are able to handle some recursive definitions.  ...  Issues of typing and language forms within the genetic programming paradigm are discussed.  ...  encouragement, and the anonymous referees for their constructive criticism.  ... 
doi:10.1007/3-540-60154-6_44 fatcat:fxgm3a25djedpmy4s67wvymnfm

Real-time and simultaneous measurement of tricuspid orifice and tricuspid anulus areas in anesthetized dogs

K Tamiya, M Higashidate, S Kikkawa
1989 Circulation Research  
Even in an isolated atrial contraction, the inflection point that marks the boundary between slow "atriogenic" closure presumably due to anulus narrowing and rapid closure presumably due to hemodynamic  ...  crossover.  ...  Acknowledgments We are grateful to the members of the animal laboratory of The Heart Institute of Japan for their expert help and hearty encouragement and to Mr.  ... 
doi:10.1161/01.res.64.3.427 pmid:2917376 fatcat:z2naeinhk5fqfb3tnn3f5yjrua

Endoscopy-Assisted Periacetabular Osteotomy

Dean K. Matsuda, Hal D. Martin, Javad Parvizi
2016 Arthroscopy Techniques  
by final dynamic hip arthroscopy to assess acetabular reorientation and fixation and to perform femoroplasty in relation to the new acetabular rim position, if needed.  ...  The endoscopy-assisted PAO was introduced to accomplish this objective.  ...  Arthroscopic capsular closure was then done (Fig 7) . The fascia lata was closed, followed by subcutaneous and skin closure.  ... 
doi:10.1016/j.eats.2016.01.017 pmid:27354947 pmcid:PMC4912685 fatcat:5f2gmbjj7fd75m5octpnzthx7m

Regional asynchrony during acute myocardial ischemia quantified by ultrasound strain rate imaging

Cristina Pislaru, Marek Belohlavek, Richard Y Bae, Theodore P Abraham, James F Greenleaf, James B Seward
2001 Journal of the American College of Cardiology  
Current techniques for detection of asynchrony are either subjective, or invasive and time-consuming.  ...  The time from electrocardiographic R-wave to the occurrence of compression/expansion crossover (T CEC ) was calculated.  ...  Pislaru for assisting with the statistical analysis. The ultrasound scanner was provided courtesy of GE Medical Systems, Milwaukee, Wisconsin.  ... 
doi:10.1016/s0735-1097(01)01113-5 pmid:11263621 fatcat:dhvzab6a3rca5gi5c2snljefcu

DNA Shuffling Method for Generating Estrogen Receptor α and β Chimeras in Yeast

Jun Sun, John A. Katzenellenbogen, Huimin Zhao, Benita S. Katzenellenbogen
2003 BioTechniques  
We would like to thank Adrienn Gabor for her exceptional assistance with software development and the design and construction of the incubator. ferent crossover sites were found; most occurred when there  ...  tension and mantle closure in Xenopus laevis gastrulation: combined roles for integrin α(5)β(1), fibronectin, and tissue geometry. .Drake, C.J., L.A. Davis, and C.D. Little. 1992.  ...  whose 3′ ends specifically match the α and β sequences, respectively, and whose 5′ ends match sequences outside the ERβ ligand binding domain.  ... 
doi:10.2144/03342st02 pmid:12613251 fatcat:qjcr2jhsgfhznc7a66kwet2ddy

Bidirectional contrast effects in the perception of VC-CV sequences

Bruno H. Repp
1983 Perception & Psychophysics  
These values matched the average VCCV closure durations of the two speakers.  ...  contrastive effect at longer closure durations, with the crossover occurring at about 130 msec of closure duration.  ...  At closure durations below approximately 70 msec, listeners generally do not perceive C,; that is, they do not interpret the formant transitions leading into the closure a cues for a separate phonetic  ... 
doi:10.3758/bf03202832 fatcat:dgpnxghx5bbshityuyutdl76ce

Model-Based Fault Detection and Identification for Prognostics of Electromechanical Actuators Using Genetic Algorithms

Matteo D. L. Dalla Vedova, Alfio Germanà, Pier Carlo Berri, Paolo Maggiore
2019 Aerospace (Basel)  
Four different failure modes are considered: dry friction, backlash, partial coil short circuit, and controller gain drift.  ...  We propose a model-based fault detection and isolation (FDI) method, employing a Genetic Algorithm (GA) to identify failure precursors before the performance of the system starts being compromised.  ...  When the error function is minimized, the RM and MM responses match at their best.  ... 
doi:10.3390/aerospace6090094 fatcat:rb3jzvoyt5agfahmy2l2f7ww5u

SUMO is a pervasive regulator of meiosis

Nikhil R Bhagwat, Shannon N Owens, Masaru Ito, Jay V Boinapalli, Philip Poa, Alexander Ditzel, Srujan Kopparapu, Meghan Mahalawat, Owen Richard Davies, Sean R Collins, Jeffrey R Johnson, Nevan J Krogan (+1 others)
2021 eLife  
Modified sites cluster in disordered regions and only a minority match consensus motifs.  ...  Execution-point analysis confirms these inferences, revealing functions for SUMO in S-phase, the initiation of recombination, chromosome synapsis and crossing over.  ...  cluster and sites located around the "safety belt", which wraps the 584 closure motifs.  ... 
doi:10.7554/elife.57720 pmid:33502312 pmcid:PMC7924959 fatcat:fsa2cp6hafe4bmjdjmmx64ph3e
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