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Thalamus and posterior temporal lobe show greater inter-network connectivity at rest and across sensory paradigms in schizophrenia
2014
NeuroImage
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(N = 53) and schizophrenia patients (N = 42) during rest and across paradigms arranged hierarchically by sensory load. ...
Although a number of recent studies have examined functional connectivity at rest, few have assessed differences between connectivity both during rest and across active task paradigms. ...
Acknowledgments The authors thank MIALAB group members and COBRE group members. Çetin et al. The authors declare no conflict of interest. ...
doi:10.1016/j.neuroimage.2014.04.009
pmid:24736181
pmcid:PMC4087193
fatcat:6wk34yign5ebthmjcvkeiz3gwi
Brain Metabolism during Hallucination-Like Auditory Stimulation in Schizophrenia
2014
PLoS ONE
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Participants were scanned twice: (1) at rest and (2) during the perception of aversive auditory stimuli mimicking the content of AVH. ...
Furthermore, patients displayed abnormally strong connections between the amygdala and auditory regions of the cortex and thalamus, along with abnormally weak connections between the amygdala and medial ...
Hypothesis one results As hypothesized, patients showed greater activation in limbic and paralimbic regions, as well as in temporal cortex and other brain regions, relative to healthy controls in the stimulation ...
doi:10.1371/journal.pone.0084987
pmid:24416328
pmcid:PMC3885666
fatcat:n7gqh6w24rcizcp3j4uwxpgixi
Females with schizophrenia have abnormal functional cortical connectivity in the gamma frequency during an auditory oddball task using magnetoencephalography
2014
Open Journal of Psychiatry
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IC between the right or left precuneus and other specific cortical areas showed dysfunction, suggesting that the parietal lobe plays an important role in dysfunction in connectivity in the gamma band during ...
IC within the high gamma band in female schizophrenia patients showed two types of functional disconnection, intrahemispheric and interhemispheric. ...
Recent developments in functional connectivity MRI (fcMRI) showed reduced functional connectivity to the parietal lobe, posterior cingulate cortex, thalamus, and striatum, and dysfunction in the frontoparietal ...
doi:10.4236/ojpsych.2014.41005
fatcat:ls3v34kpbfbjlblsgirz4onkty
Functional magnetic resonance imaging (fMRI) of attention processes in presumed obligate carriers of schizophrenia
2008
Annals of General Psychiatry
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Results: The POCs indicated alterations in a widely distributed network of regions involved in attention processes, such as the prefrontal and temporal (including the parahippocampal gyrus) cortices, in ...
, suggesting that reduced BOLD activity in the attention network may be an intermediate marker for schizophrenia. ...
For ease of comparison across groups and across tasks, activations are displayed on axial images and thresholded at z = 3.0. were no areas where rest was greater than the periods of selective attention ...
doi:10.1186/1744-859x-7-18
pmid:18834530
pmcid:PMC2569933
fatcat:mdyagz42fvdmlhv5vpvykhcgha
Exploring the Psychosis Functional Connectome: Aberrant Intrinsic Networks in Schizophrenia and Bipolar Disorder
2012
Frontiers in Psychiatry
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Bipolar subjects showed more prominent changes in ventromedial and prefrontal default mode regions whereas schizophrenia patients showed changes in posterior default mode regions. ...
Intrinsic functional brain networks (INs) are regions showing temporal coherence with one another. ...
We thank the research staff at the Olin Neuropsychiatric Research Center who helped collect and check the data. ...
doi:10.3389/fpsyt.2011.00075
pmid:22291663
pmcid:PMC3254121
fatcat:tomqytd34vdxrjyxd7ennyi2ke
Phenotypic Variability in Resting-State Functional Connectivity: Current Status
2013
Brain Connectivity
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We reviewed the extant literature with the goal of assessing the extent to which resting-state functional connectivity is associated with phenotypic variability in healthy and disordered populations. ...
A large corpus of work has accumulated to date (125 studies), supporting the association between intrinsic functional connectivity and individual differences in a wide range of domains-not only in cognitive ...
Acknowledgments and Support This work was supported by the National Institute of Mental Health (MH086709 and MH084961 to C.J.V., and MH088066 to E.M.G.). ...
doi:10.1089/brain.2012.0110
pmid:23294010
pmcid:PMC3634144
fatcat:kycgpre4orbgtdmhepuqtrveai
Decreased interhemispheric coordination in schizophrenia: A resting state fMRI study
2012
Schizophrenia Research
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We found highly significant reductions in VMHC in patients for a number of regions, particularly the occipital lobe, the thalamus, and the cerebellum. ...
These results show substantial impairment of interhemispheric coordination in schizophrenia. ...
on Schizophrenia and Depression and gifts from Linda and Richard Schaps, Jill and Bob Smith, and the Taubman Foundation to Francisco Xavier Castellanos. ...
doi:10.1016/j.schres.2012.07.027
pmid:22910401
pmcid:PMC3446206
fatcat:cyupktkccvaklk7pkx5e7w4dsi
Executive Functioning in Schizophrenia
2013
Frontiers in Psychiatry
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However, impairment in executive tests is explained by dysfunction of prefronto-striatothalamic, prefronto-parietal, and prefronto-temporal neural networks mainly. ...
Impairment in tasks measuring conceptualization, planning, cognitive flexibility, verbal fluency, ability to solve complex problems, and WM occur in schizophrenia. ...
ACKNOWLEDGMENTS The authors were funded by Fondecyt 1100975, Conicyt Chile, and PIA-CONICYT CIE 05. ...
doi:10.3389/fpsyt.2013.00035
pmid:23805107
pmcid:PMC3690455
fatcat:v6ivrynguffx3gt3ahyxqk6xl4
Brain Structural and Functional Connectivity: A Review of Combined Works of Diffusion Magnetic Resonance Imaging and Electro-Encephalography
2021
Frontiers in Human Neuroscience
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At first glance, however, the corresponding findings appear variable, both in the healthy brain and in numerous neuro-pathologies. ...
This might be caused by the diversity of paradigms being investigated, from sleep and resting state to cognitive and motor tasks, from healthy participants to patients. ...
Stins for commenting on and proofreading the manuscript. ...
doi:10.3389/fnhum.2021.721206
pmid:34690718
pmcid:PMC8529047
fatcat:4egyat5ohncshffbnfhpqo4u2m
Alteration of functional brain architecture in 22q11.2 deletion syndrome – Insights into susceptibility for psychosis
2018
NeuroImage
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Siebner has received honoraria as speaker from Sanofi Genzyme, Denmark and as senior editor (NeuroImage) from Elsevier Publishers, Amsterdam, The Netherlands. ...
The reduced amplitude at N1, was accounted for by reduced activity in cuneus, precuneus, middle temporal lobes, occipital lobes and posterior cingulate, a finding that has not been observed in schizophrenia ...
For successful stop trials, controls showed greater activation in the frontal cortex, anterior and posterior cingulate gyrus, bilateral striatum and thalamus, left parietal cortex, bilateral inferior and ...
doi:10.1016/j.neuroimage.2018.09.001
pmid:30195053
fatcat:sh3jtzkf45h5lj3npxmgpehmui
Interaction of language, auditory and memory brain networks in auditory verbal hallucinations
2017
Progress in Neurobiology
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We review 50 studies investigating functional (EEG and fMRI) and anatomic (diffusion tensor imaging) connectivity in these networks, and explore the evidence supporting abnormal connectivity in these networks ...
Specifically, possible changes in fronto-temporal connectivity are still under debate. ...
Blake and D. ffytche for their comments on earlier versions of the manuscript. The authors thank S. Hanekamp for help with preparation of figures. ...
doi:10.1016/j.pneurobio.2016.11.002
pmid:27890810
pmcid:PMC5240789
fatcat:7xksymn2bjdrfbi2ivv2oquade
Electrophysiological Assessment Methodology of Sensory Processing Dysfunction in Schizophrenia and Dementia of the Alzheimer Type
2018
Neuroscience and Biobehavioral Reviews
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Electrophysiological assessment methodology of sensory processing dysfunction in schizophrenia and dementia of the Alzheimer type Danjou, P.; Viardot, G.; Maurice, D.; Garcés, P.; Wams, E. ...
This Joint Undertaking receives support from the European Union's Horizon 2020 research and innovation programme and EFPIA. ...
Acknowledgements We would like to express our gratitude to Gerry Dawson, Amy Bilderbeck and Philippe Lhostis for their expert contribution and the European Innovative Medicine Initiative for funding. ...
doi:10.1016/j.neubiorev.2018.09.004
pmid:30195932
fatcat:axnptmkvrjcsvmjec3cw7kf3pm
Convergent approaches for defining functional imaging endophenotypes in schizophrenia
2009
Frontiers in Human Neuroscience
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ACKNOWLEDGMENTS This research was supported in part by the National Institutes of Health (NIH), under grants R01MH077945, R37 MH43775 (MERIT Award) and MH074797 to Godfrey D. ...
Pearlson: and 1 R01 EB 000840, ...
disruption, greater dependency, and greater variability of network inter-relationships, possibly refl ecting cortical processing defi ciencies. ...
doi:10.3389/neuro.09.037.2009
pmid:19956400
pmcid:PMC2786299
fatcat:42p3gjznqzdv7bkf2wfislw3zy
Associative Learning Beyond the Medial Temporal Lobe: Many Actors on the Memory Stage
2013
Frontiers in Behavioral Neuroscience
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Notice that sensory information is only partly integrated at the level of the perirhinal, parahippocampal, and entorhinal cortices. ...
We propose that these networks contribute differently to recognition memory and recall, and also that the memory stage of their contribution shows specificity to encoding or retrieval in recall tasks. ...
Notice the triangular connections involving the medial temporal lobe, the midline thalamus and the orbitofrontal, and ventromedial cortex. ...
doi:10.3389/fnbeh.2013.00162
pmid:24312029
pmcid:PMC3832901
fatcat:rdq5rups55eudijgsd4kb6ecbm
Acupuncture mobilizes the brain's default mode and its anti-correlated network in healthy subjects
2009
Brain Research
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Clusters of deactivated regions in the medial prefrontal, medial parietal and medial temporal lobes as well as activated regions in the sensorimotor and a few paralimbic structures can be identified during ...
Importantly, these clusters showed virtual identity with the default mode network and the anti-correlated task-positive network in response to stimulation. ...
Acknowledgments The work was supported in part by the NIH/National Center for Complementary and Alternative Medicine (R21AT00978) (1-P01-002048-01) (K01-AT-002166-01), the National Center for Research ...
doi:10.1016/j.brainres.2009.06.061
pmid:19559684
pmcid:PMC3742122
fatcat:rhi66wpdlrg5dh3ggln7spihk4
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