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Test–retest reliability of evoked BOLD signals from a cognitive–emotive fMRI test battery

Michael M. Plichta, Adam J. Schwarz, Oliver Grimm, Katrin Morgen, Daniela Mier, Leila Haddad, Antje B.M. Gerdes, Carina Sauer, Heike Tost, Christine Esslinger, Peter Colman, Frederick Wilson (+2 others)
2012 NeuroImage  
A group of 25 young, healthy volunteers were scanned twice on a 3 T MRI scanner with a mean test-retest interval of 14.6 days.  ...  The present study investigated both within-subject and group-level reliability of a combined three-task fMRI battery targeting three systems of wide applicability in clinical and cognitive neuroscience  ...  We thank Georg Gron for generously sharing his expertise in fMRI data analysis. Furthermore, we thank Dagmar Gass for her help with data collection.  ... 
doi:10.1016/j.neuroimage.2012.01.129 pmid:22330316 fatcat:rwr322pjvjd6lgcnrvtcypt2fq

Test-retest reliability of an fMRI paradigm for studies of cardiovascular reactivity

Lei K. Sheu, J. Richard Jennings, Peter J. Gianaros
2012 Psychophysiology  
The reliability of fMRI BOLD signal changes in brain areas engaged by the tasks was moderate, and aggregating fMRI BOLD signal changes across the tasks improved testretest reliability metrics.  ...  These findings support using these tasks as a battery for fMRI studies of cardiovascular reactivity.  ...  Acknowledgments This work was funded by National Institutes of Health Grants HL089850 and HL101421 to Peter J. Gianaros. The authors thank Sara Snyder for her assistance in data collection.  ... 
doi:10.1111/j.1469-8986.2012.01382.x pmid:22594784 pmcid:PMC3376244 fatcat:o2r54nenrff37dk7inuevwwbxq

Amygdala habituation: A reliable fMRI phenotype

Michael M. Plichta, Oliver Grimm, Katrin Morgen, Daniela Mier, Carina Sauer, Leila Haddad, Heike Tost, Christine Esslinger, Peter Kirsch, Adam J. Schwarz, Andreas Meyer-Lindenberg
2014 NeuroImage  
We extracted the amygdala signal decrement across the course of the fMRI run for the two test-retest measurement sessions and compared reliability estimates with previous findings based on mean response  ...  To test the task-specificity of this finding, we compared the retest-reliability of amygdala habituation across two different tasks.  ...  Conflict of interest Dr.  ... 
doi:10.1016/j.neuroimage.2014.09.059 pmid:25284303 fatcat:4zraelldvnavpicsnangkc2mpq

Parcellating cortical functional networks in individuals

Danhong Wang, Randy L Buckner, Michael D Fox, Daphne J Holt, Avram J Holmes, Sophia Stoecklein, Georg Langs, Ruiqi Pan, Tianyi Qian, Kuncheng Li, Justin T Baker, Steven M Stufflebeam (+4 others)
2015 Nature Neuroscience  
Evaluating Test-retest Reliability and Inter-subject Variability of the Maps Derived from the Iterative Parcellation Intra-subject test-retest reliability of the parcellation results was computed using  ...  Current preoperative mapping with task-based fMRI suffers from poor signal-to-noise ratios, limited test-retest reliability and limited overlap with analogous maps derived from invasive cortical stimulation  ... 
doi:10.1038/nn.4164 pmid:26551545 pmcid:PMC4661084 fatcat:pktkdtzigvfn7fnn2gdvyhyuxq

General Functional Connectivity: shared features of resting-state and task fMRI drive reliable individual differences in functional brain networks [article]

Maxwell L Elliott, Annchen R Knodt, M. Justin Kim, Tracy R Melzer, Ross Keenan, David Ireland, Sandhya Ramrakha, Richie Poulton, Avshalom Caspi, Terrie E Moffitt, Ahmad R Hariri
2018 bioRxiv   pre-print
Intrinsic connectivity, commonly measured using resting-state fMRI, has emerged as a fundamental feature of the brain.  ...  Our work suggests that GFC represents an opportunity to improve the reliability and predictive utility of fMRI for mapping individual differences, and that collection of resting-state and task scans need  ...  Eight subjects were removed from our test-156 retest analyses because they had at least one fMRI scan with truncated or missing data.  ... 
doi:10.1101/330530 fatcat:drygm7p5xzhllopi6g6nq3dgla

The role of fMRI in drug development

Owen Carmichael, Adam J. Schwarz, Christopher H. Chatham, David Scott, Jessica A. Turner, Jaymin Upadhyay, Alexandre Coimbra, James A. Goodman, Richard Baumgartner, Brett A. English, John W. Apolzan, Preetham Shankapal (+1 others)
2018 Drug Discovery Today  
First, task-based fMRI uses sensory or cognitive stimuli to provoke responses from brain regions or circuits involved in responding to the stimuli.  ...  Third, pharmacological MRI (phMRI) records fMRI signals following the administration of pharmacological agents [9] .  ...  It grew out of discussions that took place at the 'Functional MRI in Clinical Trials: State of the Science and Future Directions' symposium that was held December 1-3, 2015, at Pennington Biomedical Research  ... 
doi:10.1016/j.drudis.2017.11.012 pmid:29154758 pmcid:PMC5931333 fatcat:cpfshk7mnvhlpoh5sxamuuvnxu

Brain imaging predictors and the international study to predict optimized treatment for depression: study protocol for a randomized controlled trial

Stuart M Grieve, Mayuresh S Korgaonkar, Amit Etkin, Anthony Harris, Stephen H Koslow, Stephen Wisniewski, Alan F Schatzberg, Charles B Nemeroff, Evian Gordon, Leanne M Williams
2013 Trials  
Given this is a large proportion of the patient population, pretreatment tests that predict which patients will respond to which types of treatment could save time, money and patient burden.  ...  Functional studies include standardized functional magnetic resonance imaging (MRI) with three cognitive tasks (auditory oddball, a continuous performance task, and Go-NoGo) and two emotion tasks (unmasked  ...  Contrast images for each cognitive thinking and emotion processing task are generated and will be evaluated for voxel-wise comparisons in BOLD signal for the whole brain.  ... 
doi:10.1186/1745-6215-14-224 pmid:23866851 pmcid:PMC3729660 fatcat:jelldng4ibfvbnwzilsv3t5uke

The local properties of bold signal fluctuations at rest monitor inhibitory control training in adolescents

Emilie Salvia, Cloélia Tissier, Sylvain Charron, Paul Herent, Julie Vidal, Stéphanie Lion, Mathieu Cassotti, Catherine Oppenheim, Olivier Houdé, Grégoire Borst, Arnaud Cachia
2019 Developmental Cognitive Neuroscience  
We focused on the IC training effects on the local properties of functional Magnetic Resonance Imaging (fMRI) signal fluctuations at rest (i.e., Regional Homogeneity [ReHo] and fractional Amplitude of  ...  Inhibitory control (IC) plays a critical role in cognitive and socio-emotional development. Short-term IC training improves IC abilities in children and adults.  ...  Acknowledgements The study was supported by research grants from the French National Research Agency (ANR-14-CE30-0014-01 APEX) and personal grants from the Fondation pour la Recherche Médicale and Institut  ... 
doi:10.1016/j.dcn.2019.100664 pmid:31158801 pmcid:PMC6969344 fatcat:z7larx4p3fef7bvx6wm3rk6fhy

Neuroimaging in Psychiatric Pharmacogenetics Research: The Promise and Pitfalls

Mary Falcone, Ryan M Smith, Meghan J Chenoweth, Abesh Kumar Bhattacharjee, John R Kelsoe, Rachel F Tyndale, Caryn Lerman
2013 Neuropsychopharmacology  
Moreover, few studies use pharmacogenetic designs that permit testing of genotype drug effects. As a result of these limitations, few findings have been fully replicated.  ...  Neuroimaging may provide a more sensitive early measure of treatment response in genetically defined patient groups, and could facilitate development of novel therapies based on an improved understanding  ...  The issue of test-retest reliability is another consideration; some cognitive fMRI measures (such as the n-back working memory task) provide very good within-subject reproducibility, whereas others (such  ... 
doi:10.1038/npp.2013.152 pmid:23793356 pmcid:PMC3799069 fatcat:qhapaiqufzerfortgxxujxyjme

Stroop Performance in Normal Control Subjects: An fMRI Study

Staci A. Gruber, Jadwiga Rogowska, Philip Holcomb, Salvatore Soraci, Deborah Yurgelun-Todd
2002 NeuroImage  
In an attempt to clarify regional signal intensity changes, which may accompany the performance of the Stroop Color-Word task, healthy subjects were imaged using the fMRI BOLD technique while performing  ...  a modified version of the task.  ...  Considered one of the most reliable psychometric tests (Jensen et al., 1965; Uechi, 1972) , and found to remain relatively unaffected by test-retest situations (MacLeod, 1991) , the Stroop Color-Word  ... 
doi:10.1006/nimg.2002.1089 pmid:12030821 fatcat:bv2gfhpnmrf2vlkfgujpwimvau

Performing group-level functional image analyses based on homologous functional regions mapped in individuals

Meiling Li, Danhong Wang, Jianxun Ren, Georg Langs, Sophia Stoecklein, Brian P. Brennan, Jie Lu, Huafu Chen, Hesheng Liu, Matthew Rushworth
2019 PLoS Biology  
Here, we reliably identified a set of discrete, homologous functional regions in individuals to improve intersubject alignment of fMRI data.  ...  We demonstrated that aligning task-fMRI data using the regions derived from resting state fMRI may lead to increased statistical power of task-fMRI analyses.  ...  A battery of behavioral tests was performed by each participant.  ... 
doi:10.1371/journal.pbio.2007032 pmid:30908490 pmcid:PMC6448916 fatcat:cpwbevbujbgs7k26awxwzcvrni

Alterations in the neural circuitry for emotion and attention associated with posttraumatic stress symptomatology

Jasmeet Pannu Hayes, Kevin S. LaBar, Christopher M. Petty, Gregory McCarthy, Rajendra A. Morey
2009 Psychiatry Research : Neuroimaging  
In the present study, combat veterans with PTSD symptomatology engaged in an emotional oddball task while undergoing functional magnetic resonance imaging (fMRI).  ...  Participants discriminated infrequent target stimuli (circles) from frequent standards (squares) while emotional and neutral distractors were presented infrequently and irregularly.  ...  of Mental Health Grant K23 MH073091.  ... 
doi:10.1016/j.pscychresns.2008.05.005 pmid:19237269 pmcid:PMC2692949 fatcat:am4xlhl3yfflxauczwuk2ny4ne

Genetic psychophysiology: Advances, problems, and future directions

Andrey P. Anokhin
2014 International Journal of Psychophysiology  
function including resting-state brain oscillations, functional connectivity, and event-related neural activity in a variety of cognitive and emotion processing tasks, as well as peripheral psychophysiological  ...  The main goals of genetic psychophysiology are to elucidate the neural pathways and mechanisms mediating genetic influences on cognition and emotion, identify intermediate brain-based phenotypes for psychopathology  ...  Acknowledgments Supported by NIH grants DA027096 and DA01889 from the National Institute on Drug Abuse. The author thanks Tara Tinnin, M.S.W. for her help with the preparation of the manuscript.  ... 
doi:10.1016/j.ijpsycho.2014.04.003 pmid:24739435 pmcid:PMC4077936 fatcat:gglunoyv2rbzrknw4uuslznvi4

Resting-State Functional Brain Connectivity Best Predicts the Personality Dimension of Openness to Experience

Julien Dubois, Paola Galdi, Yanting Han, Lynn K. Paul, Ralph Adolphs
2018 Personality Neuroscience  
Across all results (test/retest; three denoising strategies; two alignment schemes; three models), Openness to experience emerged as the only reliably predicted personality factor.  ...  After regressing out potential confounds (such as age, sex, handedness, and fluid intelligence), we used a cross-validated framework, together with test-retest replication (across two sessions of resting-state  ...  Conflicts of Interest: The authors have nothing to disclose. Supplementary Material: To view supplementary material for this article, please visit  ... 
doi:10.1017/pen.2018.8 pmid:30225394 pmcid:PMC6138449 fatcat:ulupvsesgzc2tkmvjssvqcsq3i

Brain regions implicated in inhibitory control and appetite regulation are activated in response to food portion size and energy density in children

L K English, S N Fearnbach, M Lasschuijt, A Schlegel, K Anderson, S Harris, S J Wilson, J O Fisher, J S Savage, B J Rolls, K L Keller
2016 International Journal of Obesity  
METHODS AND DESIGN: Blood-oxygen-level-dependent (BOLD) fMRI was completed in 36 children (ages 7-10 years) after a 2-h fast while viewing food images at two levels of PS (Large PS, Small PS) and two levels  ...  CONCLUSION: This is the first fMRI study to report increased activation to large portions in a brain region that is involved in inhibitory control.  ...  Finally, preliminary test-retest data (n = 5) for Large PS vs Small PS in the right IFG demonstrated an intraclass correlation of 0.72, indicating good reliability of our paradigm, but further analyses  ... 
doi:10.1038/ijo.2016.126 pmid:27457416 fatcat:fky7w5pjy5byfck6vbuhrjui5q
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