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Management of iron deficiency anemia in hemodialysis patients based on mean corpuscular volume
2021
Renal Replacement Therapy
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Background To manage the anemic status in hemodialysis (HD) patients, a well-balanced combination therapy based on the use of erythropoiesis-stimulating agents (ESAs) and iron supplementation is essential. Serum ferritin level and transferrin saturation rate (TSAT) are the current standard tests for screening iron deficiency status. However, these are not included in frequently checked regular blood measurements in many HD centers. Other parameters that could predict a hemoglobin (Hb) increase
doi:10.1186/s41100-021-00327-x
fatcat:lk6m5224fvhk3bzcizacs4zzsu
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... esponse from iron supplementation have yet to be established. To determine a frequently checked and regularly measured biomarker for predicting iron deficiency status, this study investigated the value of mean corpuscular volume (MCV) as a clinical parameter for HD patients receiving intravenous iron supplementation (Fe-IV) therapy. Methods and results One hundred thirty four HD patients, 88 non-HD patients with anemia, and 50 HD patients on Fe-IV therapy from the Nozatomon clinic were assessed. Comparison of MCV values of anemic HD patients and anemic non-chronic kidney disease (CKD) patients showed that anemic HD patients had significantly higher MCV values (93.9 ± 7.3 fL) compared with anemic non-CKD patients (82.8 ± 8.8fL). Fifty HD patients, who received Fe-IV therapy at ten consecutive HD sessions (inclusion criteria: Hb ≤ 12.0 g/dL, TSAT < 20%, and serum ferritin < 100 ng/mL) showed a rapid increase during the Fe-IV period in MCV, Hb, and TSAT levels. After the completion of the Fe-IV therapy, MCV persisted at the increased levels, whereas Hb levels further increased and peaked at 1 month with a gradual decline after, largely influenced by ESA dosage reductions. The 50 patients were divided into three groups according to the MCV levels obtained immediately prior to the Fe-IV therapy (MCV ≤ 85 fL, 85 fL < MCV ≤ 90 fL, MCV > 90 fL), and Hb changes at 50 days after the initiation of the Fe-IV therapy were compared. All the patients in the MCV ≤ 85 fL group and most of the patients in the 85 fL < MCV ≤ 90 fL group showed linear and consistent Hb increase during the 50-day period. In marked contrast, patients in the MCV > 90 fL group showed dispersed trends in their Hb increase. The present study also revealed that successful ESA dosage reduction could be achieved after the Fe-IV therapy in both the MCV ≤ 85 fL and 85 fL < MCV ≤ 90 fL groups. Conclusions The present study underscored the value of MCV in perceiving iron deficiency status as well as predicting iron-based therapeutic response in HD patients.
Extracting Elementary Terms from Dictionaries
用語集からの要素語推定の試み
1995
Proceedings of Annual Conference Japan Society of Information and Knowledge
用語集からの要素語推定の試み
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Because many of Japa 皿 ese terms in variety fields ca 皿 be regarded as co 皿 posite ter 皿 s , decomPosing ter 皿 s into elementary ter 皿 s see 皿 s to be helpful to understand about ter 皿 8 . 1》 eco 皿 Posing terms , iセ is neccessary to decide a basic set of elemelltary terms . In this
doi:10.2964/jsikproc.3.0_25
fatcat:qo53scwu4fdqtcoy3d25tpi3qa
Dispersion Hardening of Cu–Al–Ti Alloys by Internal Oxidation
1985
Transactions of the Japan Institute of Metals
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*calculated
mass ratio
Fig.9
Effect of internally
oxidizing
temperature
on the
Teruo Takahashi,
Yasuhiko
Hashimoto,
Shinichiro
Omori
and Koichiro
Koyama
especially for the improvement ...
doi:10.2320/matertrans1960.26.271
fatcat:5veqat7wwvgpraankj6v5fmqse
FORMATION OF THE INVERTED HEXAGONAL STRUCTURE IN BOVINE BRAIN PHOSPHOLIPID MEMBRANES INDUCED BY DIOLEOYLGLYCEROL
1996
Biomedical research
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To evaluate the diacylglycerol (DG) concentration that may induce the membrane fusion, we examined the formation of the inverted hexagonal (H11) structure in the multilamellar vesicles comprised of bovine brain phosphatidylcholine (BBPC), bovine brain phosphatidylethanolamine (BBPE) and cholesterol (1 : 1: 1 molar ratio) in the absence or presence of a small amount of dioleoylglycerol (DOG). These lipid layers are considered as the model system for the secreting cell membranes. The formation of
doi:10.2220/biomedres.17.287
fatcat:5hd4wy75f5ctxovjyr4advylva
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... the HM structure was detected using "P-NMR and fluorescence techniques. The fluorescent probe used was N-(dimethylaminonaphthalene-5-
Stractural Analysis of Japanese Medical Terms
日本語医学専門用語の構造解析
1994
Proceedings of Annual Conference Japan Society of Information and Knowledge
日本語医学専門用語の構造解析
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Deverbal compound noun analysis based on lexical conceptual structure
2003
Proceedings of the 41st Annual Meeting on Association for Computational Linguistics - ACL '03
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This paper proposes a principled approach for analysis of semantic relations between constituents in compound nouns based on lexical semantic structure. One of the difficulties of compound noun analysis is that the mechanisms governing the decision system of semantic relations and the representation method of semantic relations associated with lexical and contextual meaning are not obvious. The aim of our research is to clarify how lexical semantics contribute to the relations in compound nouns
doi:10.3115/1075178.1075211
dblp:conf/acl/TakeuchiKK03
fatcat:2xmnshl7mbhe5psm73qxdrxwjy
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... since such nouns are very productive and are supposed to be governed by systematic mechanisms. The results of applying our approach to the analysis of noun-deverbal compounds in Japanese and English show that lexical conceptual structure contributes to the restrictional rules in compounds.
Unexpected Impingement Corrosion of Aluminum Brass Condenser Tubes
復水器用アルミニウム黄銅管の早期潰食事例についての一考察
1979
Corrosion engineering digest
復水器用アルミニウム黄銅管の早期潰食事例についての一考察
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Some discussions about the mechanism of the unexpected severe impingement corrosion of condenser tubes were made in relation to hydrotalcite. It was elucidated experimentally that hydrotalcite is the initial corrosion product of Aluminum Brass in the natural sea water. Even if iron rich protective films are formed on hydrotalcite, they will be broken quite easily by the collision of foreign bodies with smaller energy in the sea water. This will increase the possibility of corrosion. The most
doi:10.3323/jcorr1974.28.9_485
fatcat:j3mytejrizckbm6vgjslom4j7m
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... ortant countermeasure is to supress the initial corrosion of condenser tubes by the effective ferrous ion dosing and to prevent hydrotalcite formation. It was pointed out that more attension should be paid to hydrotalcite from the standpoint of corrosion engineering of condenser tubes.
Creep damage evaluation of boiler tubes
ボイラ伝熱管のクリープ損傷評価
1990
Journal of the Society of Materials Science Japan
ボイラ伝熱管のクリープ損傷評価
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ABSORPTION, METABOLISM AND EXCRETION OF RU 28965 IN HUMANS
健常人におけるRU 28965の吸収, 代謝及び排泄に関する研究
1988
Chemotherapy
健常人におけるRU 28965の吸収, 代謝及び排泄に関する研究
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Monophasic primary renal synovial sarcoma accompanied with a hemorrhagic cyst
2011
Urology Journal
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A pheochromocytoma of urinary bladder treated with neoadjuvant chemotherapy
2009
Hinyokika kiyo. Acta urologica Japonica
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A 69-year-old female presented with hypertension and a solid mass in the bladder on ultrasonography. Cystoscopy revealed a submucosal tumor in the right lateral wall of the bladder. A transurethral resection was performed. Histologically, pathologic examination revealed a malignant pheochromocytoma. She refused surgical therapy and radiation therapy. She had no treatment for two years. She suddenly complained of gross hematuria. T2-weighted magnetic resonance imaging showed a bladder tumor of
pmid:20048562
fatcat:yny2ldctufdvhj3v25ipbw5pjq
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... gh intensity and extra-bladder invasion. She was treated with chemotherapy (CVD) for 26 cycles. Since the tumor size was reduced, she was referred to our hospital for operative indication. Partial cystectomy was performed. Histologically, the tumor was a pheochromocytoma of the urinary bladder. Ten months after the operation, she has no clinical evidence of recurrence.
Microscopic Origin of Interfacial Dzyaloshinskii-Moriya Interaction
[article]
2017
arXiv
pre-print
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Chiral spin textures at the interface between ferromagnetic and heavy nonmagnetic metals, such as Neel-type domain walls and skyrmions, have been studied intensively because of their great potential for future nanomagnetic devices. The Dyzaloshinskii-Moriya interaction (DMI) is an essential phenomenon for the formation of such chiral spin textures. In spite of recent theoretical progress aiming at understanding the microscopic origin of the DMI, an experimental investigation unravelling the
arXiv:1704.02900v1
fatcat:m4lsku64mjhbpkqmnmlgiwuj5y
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... ics at stake is still required. Here, we experimentally demonstrate the close correlation of the DMI with the anisotropy of the orbital magnetic moment and with the magnetic dipole moment of the ferromagnetic metal. The density functional theory and the tight-binding model calculations reveal that asymmetric electron occupation in orbitals gives rise to this correlation.
Study of Autoanalyzing Electrocardiograph for Rats and Mice
ラット・マウス用自動解析心電計に関する研究
1989
Advances in Animal Cardiology
ラット・マウス用自動解析心電計に関する研究
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The authors have developed a restraining device which allows the operator to record electrocardiograms (ECGs) of the rat under the non-anesthetic condition.
doi:10.11276/jsvc1984.22.16
fatcat:5vaw7enwpbetxnu7377mwal2ai
Phase and Morphology of ZrO2 in Internally Oxidized Dilute Cu–Zr Alloys
1986
Transactions of the Japan Institute of Metals
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Teruo Takahashi
et al.
nal oxidation
decreased
with the concentration
of alloying element(1). The maximum
values of
microvickers
hardness
shown
in Fig. 9 ap-
peared near 1173 K. ...
doi:10.2320/matertrans1960.27.552
fatcat:5yuu7fislva75eopcnxyphmoj4
A Study on Air-jet Looms
1961
Journal of the Textile Machinery Society of Japan
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Injection of the weft by air-jet into the free air or shed has been studied with the aid of several experimental devices. The main results obtained from this study are: 2. Laval tubes are unfit for weft propulsion. 3. The air speed drops sharply near the nozzle, and is exceeded, in the middle of the shed, by the running speed of the weft. 4. How to remove the point (whene the air speed is exceeded by the running speed of the weft as far as possible from the nozzle with the least possible
doi:10.4188/jte1955.7.28
fatcat:sdzzyylsmndafgzxa33uzpmtzq
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... nal comsumption of horsepower for air compression is a problem which awaits further inquiry. 1.
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