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Temporal trajectory of brain tissue property changes induced by electroconvulsive therapy

L Gyger, C Ramponi, J F Mall, K Swierkocz-Lenart, D Stoyanov, A Lutti, A von Gunten, F Kherif, B Draganski
2021 NeuroImage  
Improvements in depression symptom severity over time were associated with changes in both volume estimates and brain tissue properties expanding beyond mesial temporal lobe structures to anterior cingulate  ...  The obtained results stemming from multi-contrast MRI quantitative data provided a fingerprint of ECT-induced brain tissue changes over time that are contrasted against the background of established morphometry  ...  This work was carried out on the MRI platform of the Département des Neurosciences Cliniques -Centre Hospitalier Universitaire Vaudois (CHUV), which is generously supported by the ROGER DE SPOELBERCH and  ... 
doi:10.1016/j.neuroimage.2021.117895 pmid:33617994 fatcat:g6kk43wwgfadlk3ul6iqtpfiz4

The role of physiological complexity changes in resting-state EEG in clinical effectiveness of rTMS and tDCS in treatments of resistant depression [article]

Milena Cukic
2019 arXiv   pre-print
We also compare the changes of complexity in electroencephalogram (EEG) and electrocardiogram (ECG), as potential future predictors of therapy outcome.  ...  We are comparing our previous results about the complexity changes induced by repetitive Transcranial Magnetic Stimulation (rTMS), and transcranial direct current stimulation (tDCS) which are known to  ...  field and brain tissue.  ... 
arXiv:1903.10626v1 fatcat:ku766kaa2rd5jkp5ix73nwjs2a

The influence of DNA methylation on gene expression involved in the etiology and treatment of psychiatric disorders [article]

Mads Dyrvig
2015 The PhD Series of theThe PhD Series of the Faculty of Medicine  
This work was supported by the Danish Medical Research Council, NeuroSearch A/S, A.P. Møller Foundation and the NOVO Nordisk Foundation. The authors declare no conflict of interest. Appendix A.  ...  Acknowledgments This work was supported by The Obel Family Foundation and Fonden til Laegevidenskabens Fremme.  ...  Comparisons of tissue types included four brain regions (frontal cortex, temporal cortex, cerebellum, and pons) and peripheral blood.  ... 
doi:10.5278/vbn.phd.med.00024 fatcat:hmjtdawr5fcjlc6j3cq5z5x5ty

Bioelectromagnetics, complex behaviour and psychotherapeutic potential

D. T. Pooley
2010 QJM: Quarterly journal of medicine  
RF exposures and induced changes in the EEG The EEG is a dynamic and complex physiological signal and integrative reporter of brain function.  ...  Other therapeutic modalities are available such as electroconvulsive therapy and, more recently, trans-cranial magnetic stimulation. 1 These techniques involve the induction of currents using contact  ... 
doi:10.1093/qjmed/hcq079 pmid:20558407 fatcat:p2anlxt6v5hhpmc67fpzt6fhzm

Pathology of non-thermal irreversible electroporation (N-TIRE)-induced ablation of the canine brain

John H. Rossmeisl, Paulo A. Garcia, John L. Roberston, Thomas L. Ellis, Rafael V. Davalos
2013 Journal of Veterinary Science  
Lesion size correlated to the intensity of the applied electrical field. N-TIRE-induced lesions were characterized by parenchymal necrosis and hemorrhage; however, large blood vessels were preserved.  ...  This study describes the neuropathologic features of normal canine brain ablated with non-thermal irreversible electroporation (N-TIRE).  ...  Acknowledgments This work was supported in part by the Wallace Coulter and National Science Foundations (NSF-CBET 0933335). The authors thank Dr. Bernard Jortner, Dr. Elankumaran Subbiah, Ms.  ... 
doi:10.4142/jvs.2013.14.4.433 pmid:23820168 pmcid:PMC3885737 fatcat:orifrnzfvzck5mc7lp2lbtsv4u

Linking Mitochondria to Synapses: New Insights for Stress-Related Neuropsychiatric Disorders

Freddy Jeanneteau, Margarita Arango-Lievano
2016 Neural Plasticity  
The coincidence of BDNF and GR signaling changes glucocorticoid signaling output with consequences on mitochondrial respiration efficiency, synaptic plasticity, and adaptive trajectories.  ...  The brain evolved cellular mechanisms for adapting synaptic function to energy supply. This is particularly evident when homeostasis is challenged by stress.  ...  Acknowledgments The authors are supported by CNRS, INSERM, and the University of Montpellier and they thank the Marie Curie Action, the foundation Jean Valade, and the Fondation de France for sponsoring  ... 
doi:10.1155/2016/3985063 pmid:26885402 pmcid:PMC4738951 fatcat:i7asfohqfbbbzpbav74l7paqmu

Characterizing and Modulating Brain Circuitry through Transcranial Magnetic Stimulation Combined with Electroencephalography

Faranak Farzan, Marine Vernet, Mouhsin M. D. Shafi, Alexander Rotenberg, Zafiris J. Daskalakis, Alvaro Pascual-Leone
2016 Frontiers in Neural Circuits  
However, the resulting electrical field is still several orders of magnitude smaller than the field induced by TMS.  ...  We conclude by reviewing the application of TMS-EEG in basic, cognitive and clinical neurosciences, and evaluate the potential of this emerging technology in brain research.  ...  therapy (e.g., rTMS, Electroconvulsive Therapy, transcranial Direct Current Stimulation), cognitive training, physical exercise, or a combination of interventions Kahkonen and Wilenius, 2007; Barr et  ... 
doi:10.3389/fncir.2016.00073 pmid:27713691 pmcid:PMC5031704 fatcat:2jjsolbasfhc7eglq3d2se4dgi

Mind Control as a Guide for the Mind [article]

John D. Medaglia, Perry Zurn, Walter Sinnott-Armstrong, Danielle S. Bassett
2017 arXiv   pre-print
While historically a number of tools have been employed to modulate mental states (such as cognitive behavioral therapy and brain stimulation), theoretical frameworks to guide these interventions - and  ...  The human brain is a complex network that supports mental function.  ...  The content is solely the responsibility of the authors and does not necessarily represent the official views of any of the funding agencies.  ... 
arXiv:1610.04134v2 fatcat:n7heylmgn5au7hkjocgsfqpim4

Optical measurements of absorption changes in two-layered diffusive media

Francesco Fabbri, Angelo Sassaroli, Michael E Henry, Sergio Fantini
2004 Physics in Medicine and Biology  
We have applied all three methods of data analysis to near-infrared data collected on the forehead of a human subject during electroconvulsive therapy.  ...  is significantly affected by absorption changes in the superficial layer and (3) method (c) yields the absorption changes for both layers with a relatively good accuracy of ∼4% for the superficial layer  ...  We acknowledge support from the National Institutes of Health (grant no. DA14178) and from the National Science Foundation (award no. BES-93840).  ... 
doi:10.1088/0031-9155/49/7/007 pmid:15128197 fatcat:bq3nklcpbfbs7leysztfmbyzpi

Animal Models of Infantile Spasms: Is the Holy Grail Finally in Sight?

2008 Epilepsy Currents  
Progress toward understanding the pathophysiology of this disorder and the development of effective therapies has been hindered by the lack of a relevant animal model.  ...  METHODS: The sodium channel blocker, tetrodotoxin (TTX), was chronically infused into the developing neocortex or hippocampus of infant rats by way of an osmotic minipump starting on postnatal day 10-12  ...  However, this attractive possibility must take into account that the protein can also provoke effects in brain tissue, such as alterations in blood-brain barrier permeability properties, increased vessel  ... 
doi:10.1111/j.1535-7511.2008.00267.x pmid:18852836 pmcid:PMC2566614 fatcat:ci74mdumxvcflc3qbrjttus37m

VEGF As a Target for Neuroprotection

2008 Epilepsy Currents  
Progress toward understanding the pathophysiology of this disorder and the development of effective therapies has been hindered by the lack of a relevant animal model.  ...  METHODS: The sodium channel blocker, tetrodotoxin (TTX), was chronically infused into the developing neocortex or hippocampus of infant rats by way of an osmotic minipump starting on postnatal day 10-12  ...  However, this attractive possibility must take into account that the protein can also provoke effects in brain tissue, such as alterations in blood-brain barrier permeability properties, increased vessel  ... 
doi:10.1111/j.1535-7511.2008.00269.x pmid:18852838 pmcid:PMC2566616 fatcat:yzbn4aikubcctk5l2he4bakuxi

GABA Regulates Stem Cell Proliferation before Nervous System Formation

2008 Epilepsy Currents  
Progress toward understanding the pathophysiology of this disorder and the development of effective therapies has been hindered by the lack of a relevant animal model.  ...  METHODS: The sodium channel blocker, tetrodotoxin (TTX), was chronically infused into the developing neocortex or hippocampus of infant rats by way of an osmotic minipump starting on postnatal day 10-12  ...  However, this attractive possibility must take into account that the protein can also provoke effects in brain tissue, such as alterations in blood-brain barrier permeability properties, increased vessel  ... 
doi:10.1111/j.1535-7511.2008.00270.x pmid:18852839 pmcid:PMC2566617 fatcat:bhtdypuqurfi3e7s7lvgutf3cm

Is Epilepsy a Disease of Synaptic Transmission?

2008 Epilepsy Currents  
However, this attractive possibility must take into account that the protein can also provoke effects in brain tissue, such as alterations in blood-brain barrier permeability properties, increased vessel  ...  J Neurosci 23:10841-10851] finding that VEGF mRNA increases in areas of the brain that are susceptible to cell loss after electroconvulsive-shock induced seizures.  ...  These studies indicated that formation of new glutamatergic synapses on principal neurons was a key feature of temporal lobe epilepsy (2) .  ... 
doi:10.1111/j.1535-7511.2008.00271.x pmid:18852840 pmcid:PMC2566618 fatcat:hpreihedozgyvlrgum5fyzfqw4

The Molecular and Cellular Mechanisms of Axon Guidance in Mossy Fiber Sprouting

Ryuta Koyama, Yuji Ikegaya
2018 Frontiers in Neurology  
trajectories of sprouted mossy fibers in the epileptic brain.  ...  Here, we review the molecular and cellular mechanisms of axon guidance in mossy fiber sprouting by discussing mainly in vitro studies.  ...  The expression of BDNF mRNA (41) and protein (42) , as well as its high-affinity receptor TrkB (43) , are upregulated in hippocampal tissues from human epileptic brains.  ... 
doi:10.3389/fneur.2018.00382 pmid:29896153 pmcid:PMC5986954 fatcat:biqsmsr575f3zdtxmkma4zguiu

2016 Biennial Meeting of the American Society for Stereotactic and Functional Neurosurgery, Chicago, IL, USA, June 18-21, 2016: Abstracts

2016 Stereotactic and Functional Neurosurgery  
Patients receiving SCC DBS for depression represented the bulk of the LTFU (3658 patient-months or 304.8 patient-years), followed by Anorexia Nervosa (650 patient-months or 54.2 patient-years) and Bipolar  ...  Results A total of 4402 patient-months (366.8 patient-years) of followup were provided to all groups.  ...  are refractory to conventional treatments, including pharmaceuticals, behavioral therapy, and electroconvulsive therapy.  ... 
doi:10.1159/000455386 pmid:28092908 fatcat:dfobre7vdfcqvekxhbc4aekwgy
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