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Temporal representation of care trajectories of cancer patients using data from a regional information system: an application in breast cancer
2014
BMC Medical Informatics and Decision Making
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We developed an algorithm for extracting temporally represented care trajectories from coded information collected routinely by the general cancer Registry in Poitou-Charentes region, France. ...
The present work aimed to assess the performance of this algorithm on real-life patient data in the setting of non-metastatic breast cancer, using measures of similarity. ...
Acknowledgments The authors would like to thanks all the all the pathologists, departments of medical data processing in public and private hospitals, oncologists, and medical practitioners for their valuable ...
doi:10.1186/1472-6947-14-24
pmid:24690482
pmcid:PMC3983896
fatcat:kulc2f4i5bd2nkvm6j6zmtzlvq
Systems Biology of Cancer Metastasis
2019
Cell Systems
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We also highlight the gaps in our current understanding of cancer metastasis as well as insights emerging from interdisciplinary systems biology approaches to understand this complex phenomenon. ...
The lack of a systemic understanding of this complex phenomenon has limited progress in developing treatments for metastatic disease. ...
Nancy Boudreau from the National Cancer Institutes for providing constructive criticisms in support in writing the manuscript. ...
doi:10.1016/j.cels.2019.07.003
pmid:31465728
pmcid:PMC6716621
fatcat:gxyvneow5jf3xflyrxd3hycczm
An information model for computable cancer phenotypes
2016
BMC Medical Informatics and Decision Making
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of cancer care. ...
Methods: Reviews of existing ontologies and interviews with cancer researchers were used to inform iterative development of a cancer phenotype information model. ...
The use of the HL7 FHIR data model bridges the gap between two key applications of patient data: data resulting from direct clinical care and secondary use of clinical data for research purposes. ...
doi:10.1186/s12911-016-0358-4
pmid:27629872
pmcid:PMC5024416
fatcat:5az7amhx4zgwjph74cmcdd64d4
Human-Centered Text Mining: A New Software System
[chapter]
2012
Lecture Notes in Computer Science
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In this paper we introduce a novel human-centered data mining software system which was designed to gain intelligence from unstructured textual data. ...
At the core of the system are concept lattices which can be used to interactively explore the data. ...
Jonas Poelmans is Aspirant of the "Fonds voor Wetenschappelijk Onderzoek -Vlaanderen" (FWO) or Research Foundation -Flanders. ...
doi:10.1007/978-3-642-31488-9_21
fatcat:dlmifsydgfd4vl6obdrbtuhmrm
Modeling human eye behavior during mammographic scanning: preliminary results
1997
IEEE transactions on systems, man and cybernetics. Part A. Systems and humans
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the promise of eventual adaptation as a source of diagnostic information in clinical practice. ...
Understanding how people acquire information from pictures-radiographs, maps, charts, photographs, drawings, and other static images-can be an important component in understanding, aiding, and eventually ...
(See [37] for an excellent and readable summary of the epidemiology of breast cancer). Mammography is a means of imaging breast tissue using X-rays. ...
doi:10.1109/3468.594915
fatcat:hslng2owwne5beoflbwhufdnni
Mathematical models of breast and ovarian cancers
2016
Wiley Interdisciplinary Reviews: Systems Biology and Medicine
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from a systems biology perspective are needed. ...
Human breast cancers In 2016, it is estimated that 246,660 new cases of breast cancer with an estimated 40,450 deaths related to the disease will occur in the US, for a calculated 4:25 death to incidence ...
ACKNOWLEDGEMENTS Funding: The work was supported by the Intramural Research Program of the National Institutes of Health, Center for Cancer Research, National Cancer Institute as part of a seed grant from ...
doi:10.1002/wsbm.1343
pmid:27259061
pmcid:PMC4911289
fatcat:fhlkj6j3rfbcnfwsvud23tfnbe
Contextualizing the Young Adult Female Breast Cancer Experience: Developmental, Psychosocial, and Interpersonal Influences
2017
The Qualitative Report
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Future studies should explore the ways in which medical providers attend to these systems across the breast cancer trajectory. ...
Using a phenomenological approach, 23 breast cancer survivors were interviewed using a semi-structured interview. ...
the breast cancer trajectory, as well as the potential avenues for reconciling patient care and needs. ...
doi:10.46743/2160-3715/2017.2596
fatcat:4kjos6733vbthhy2rp6cz5sw74
Cancer systems immunology
2020
eLife
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While in its infancy, the field of 'Cancer Systems Immunology' has already influenced our understanding of tumor immunology and immunotherapy. ...
These advances have coincided with an exponential growth in the development of –omics technologies. ...
The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.
Additional information ...
doi:10.7554/elife.53839
fatcat:xx4k5vorbraqlkvzjbrjhjw5py
Development and validation of clinical prediction models for breast cancer incidence and mortality: a protocol for a dual cohort study
2022
BMJ Open
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It will evaluate a set of modelling approaches to predict the risk of developing breast cancer within the next 10 years, the 'combined' risk of developing a breast cancer and then dying from it within ...
10 years, and the risk of breast cancer mortality within 10 years of diagnosis. ...
This project will involve data derived from patient-level information collected by the NHS, as part of the care and support of cancer patients. ...
doi:10.1136/bmjopen-2021-050828
pmid:35351695
pmcid:PMC8961149
fatcat:nukps6cgjnbjzcn55nxv3vtqjy
A contribution to the discovery of multidimensional patterns in healthcare trajectories
2014
Journal of Intelligent Information Systems
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We introduce a case-study on real-world data from a regional healthcare system and we point out the usefulness of the extracted patterns. ...
Sequential pattern mining is aimed at extracting correlations among temporal data. ...
Acknowledgments The authors would like to thank the French institution "Institut National du Cancer (INCa)" for its financial support. ...
doi:10.1007/s10844-014-0309-4
fatcat:bxabwtksz5b5dgsglvelccf55y
Integrated care pathway for breast cancer: a relational and geographical approach
2020
Social Science and Medicine
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minutes, in-depth interviews) and quantitative data relating to the mobility and geographical location of a cohort of 1798 patients treated in this centre. ...
This inseparability is constructed from the proposal of a method for mapping the integrated care pathways in their territories. ...
After a few background information on the French health care system and cancer care, we present the case study. ...
doi:10.1016/j.socscimed.2020.113658
pmid:33421916
fatcat:zcgifd6ob5ar7ogsjfn3hdkbai
Recent Advances in Systems and Network Medicine: Meeting Report from the First International Conference in Systems and Network Medicine
2020
Systems Medicine
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Topics ranged from: Systems and Network Medicine in Clinical Practice; the role of -omics technologies in Health Care; the role of Education and Ethics in Clinical Practice, Systems Thinking, and Rare ...
The conference served as a unique nexus for interdisciplinary discovery and dialogue and fostered formation of new insights and possibilities for health care systems advances. ...
Maddipatla, Baby A. Satravada, Bharath K. ...
doi:10.1089/sysm.2020.0001
pmid:32226924
pmcid:PMC7099876
fatcat:4acs6ozyxjdrxhwya735k6k5wm
Health—exploring complexity: an interdisciplinary systems approach HEC2016
2016
European Journal of Epidemiology
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the risks and matters of patients not under care and an increase in time to collect information from the computer before starting patient care. ...
The template was evaluated by an application system expert and through conducting a first test mapping of real-world data from one of the systems. ...
In this context, a focused crawler uses techniques from the field of machine learning to estimate the relevance of a webpage for the domain of interest [5,6]. ...
doi:10.1007/s10654-016-0183-1
pmid:27522353
fatcat:dcl3nbpygvh5fg7keri74h55ie
Abstracts From the 22nd Annual Health Care Systems Research Network Conference, April 13–16, 2016, Atlanta, Georgia
2016
Journal of Patient-Centered Research and Reviews
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of human health, the care of the individual patient, and the care of populations. ...
Conclusion: Anesthesia exposure was not associated with an increased risk of dementia or AD in older adults. ...
A5-3: Universal Screen for Lynch Syndrome in an ...
doi:10.17294/2330-0698.1413
fatcat:dvytsofskrh5bb7r2atlpyogmm
Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology
2018
Journal of Alzheimer's Disease
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The Precision Neurology development process implements systems theory with system biology and neurophysiology in a parallel, bidirectional research path: a combined hypothesis-driven investigation of systems ...
dysfunction within distinct molecular, cellular and large-scale neural network systems in both animal models as well as through tests for the usefulness of these candidate dynamic systems biomarkers in ...
applied to breast cancer patients to determine their risk of reappearance, can be used in prostate cancer as well for predicting which individual may take advantage from early initiation of post-operative ...
doi:10.3233/jad-179932
pmid:29562524
pmcid:PMC6008221
fatcat:j3u6gkzfqbg47kv4o2hpkjadn4
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