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Task activations produce spurious but systematic inflation of task functional connectivity estimates [article]

Michael W Cole, Takuya Ito, Douglas Schultz, Ravi Mill, Richard Chen, Carrisa Cocuzza
<span title="2018-03-30">2018</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
the temporal similarity of task-activated brain regions regardless of whether they were actually functionally connected.  ...  Utilizing a neural mass computational model we found that task activations substantially and inappropriately inflate task-state functional connectivity (FC) estimates (temporal correlations), especially  ...  Acknowledgements: The authors acknowledge support by the US National Institutes of Health under awards R01 AG055556 and R01 MH109520. Data were provided, in part, by the Human Connectome  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/292045">doi:10.1101/292045</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/mssqrhzhovel3muxlki6ujw4rq">fatcat:mssqrhzhovel3muxlki6ujw4rq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190504183003/https://www.biorxiv.org/content/biorxiv/early/2018/10/10/292045.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/f0/70/f07003f208738221a95909b50742b11306a8389d.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/292045"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

Task activations produce spurious but systematic inflation of task functional connectivity estimates

Michael W. Cole, Takuya Ito, Douglas Schultz, Ravi Mill, Richard Chen, Carrisa Cocuzza
<span title="2018-12-28">2019</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
Task-state functional connectivity (FC) - statistical association between brain activity time series during task performance - moves beyond task-evoked activations by quantifying functional interactions  ...  Utilizing a neural mass computational model, we verified that task-evoked activations substantially and inappropriately inflate task-state FC estimates, especially in functional MRI (fMRI) data.  ...  The content is solely the responsibility of the authors and does not necessarily represent the official views of any of the funding agencies.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2018.12.054">doi:10.1016/j.neuroimage.2018.12.054</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30597260">pmid:30597260</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6422749/">pmcid:PMC6422749</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/7hmvkxb6u5eotfvc5lk2errjwq">fatcat:7hmvkxb6u5eotfvc5lk2errjwq</a> </span>
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Poor test-retest reliability of task-fMRI: New empirical evidence and a meta-analysis [article]

Maxwell L Elliott, Annchen R Knodt, David Ireland, Meriwether L Morris, Richie Polton, Sandhya Ramrakha, Maria L Sison, Terrie E Moffitt, Avshalom Caspi, Ahmad Hariri
<span title="2019-06-24">2019</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Measuring brain activity using task-fMRI is a major focus of biomarker development; however, the reliability of task-fMRI has not been systematically evaluated.  ...  Second, the test-retest reliabilities of activity in a priori regions of interest across 11 commonly used fMRI tasks collected in the Human Connectome Project and the Dunedin Longitudinal Study were poor  ...  threshold) because of the documented spurious inflation of effect sizes that occur when only statistically significant estimates are reported 14, 40, 41 .  ... 
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<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200311063425/https://www.biorxiv.org/content/biorxiv/early/2019/07/22/681700.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/b9/4d/b94de6139f7526871fc81a3d290c7a89b3033bf0.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/681700"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

Evidence for Two Independent Factors that Modify Brain Networks to Meet Task Goals

Caterina Gratton, Timothy O. Laumann, Evan M. Gordon, Babatunde Adeyemo, Steven E. Petersen
<span title="">2016</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/5ihveavyobfs3mlzee7cjt7mfe" style="color: black;">Cell Reports</a> </i> &nbsp;
Classes of regions with these two properties show distinct patterns of network changes, suggesting they index dissociable factors for modifying brain networks in a task.  ...  Graphical Abstract Highlights d Human brain networks differ between rest and task at activated and hub regions d Regions stratified by activation and hub-status show distinct FC-related attributes d Activated  ...  Note that FC was calculated after removing evoked activations from the task time series via regression to reduce spurious inflations of correlation measurements from co-activation as in Al-Aidroos et al  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.celrep.2016.10.002">doi:10.1016/j.celrep.2016.10.002</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27783943">pmid:27783943</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5123792/">pmcid:PMC5123792</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/thhmceywizggdmsps2jlo7c2vq">fatcat:thhmceywizggdmsps2jlo7c2vq</a> </span>
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Genuine cross-frequency coupling networks in human resting-state electrophysiological recordings

Felix Siebenhühner, Sheng H. Wang, Gabriele Arnulfo, Anna Lampinen, Lino Nobili, J. Matias Palva, Satu Palva, David Poeppel
<span title="2020-05-06">2020</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/tsaumnzpkvdmvdi3blhl5clb24" style="color: black;">PLoS Biology</a> </i> &nbsp;
We developed a novel, to our knowledge, graph-theoretical method to distinguish genuine CFC from spurious CFC that may arise from nonsinusoidal signals ubiquitous in neuronal activity.  ...  We posit that interareal CFC may be essential for large-scale coordination of neuronal activity and investigate here whether genuine CFC networks are present in human resting-state (RS) brain activity.  ...  The connection densities are reduced by removing putatively spurious connections but remain significantly above the zero.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pbio.3000685">doi:10.1371/journal.pbio.3000685</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/32374723">pmid:32374723</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ffoedxvmhvc7pc6j4ii6cn4xoa">fatcat:ffoedxvmhvc7pc6j4ii6cn4xoa</a> </span>
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Inferring task-related networks using independent component analysis in magnetoencephalography

H. Luckhoo, J.R. Hale, M.G. Stokes, A.C. Nobre, P.G. Morris, M.J. Brookes, M.W. Woolrich
<span title="">2012</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
This is achieved by estimating the distribution of functional connectivity scores between nodes of known resting-state networks and contrasting it with a distribution of artefactual scores that are entirely  ...  First, we systematically investigate optimisation of time-frequency windows for connectivity measurement.  ...  Acknowledgments We would like to acknowledge the following institutions for their support: the RCUK Digital Economy programme for provision of funding for Henry Luckhoo through the Centre for Doctoral  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2012.04.046">doi:10.1016/j.neuroimage.2012.04.046</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/22569064">pmid:22569064</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3387383/">pmcid:PMC3387383</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/wgic32cxanhpnoz2fb7jzwuosm">fatcat:wgic32cxanhpnoz2fb7jzwuosm</a> </span>
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Potentiation of motor sub-networks for motor control but not working memory: Interaction of dACC and SMA revealed by resting-state directed functional connectivity

Vaibhav A. Diwadkar, Avisa Asemi, Ashley Burgess, Asadur Chowdury, Steven L. Bressler, Dewen Hu
<span title="2017-03-09">2017</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a> </i> &nbsp;
directed functional connectivity.  ...  We applied directed functional connectivity analysis to these two task paradigms, and also to the rest condition of each paradigm, in which rest blocks were interspersed with task blocks.  ...  Using the mass analyses of resting state data, it has recently been suggested that cluster based methods result in inflated false-positive rates identifying clusters that are spurious [18] .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0172531">doi:10.1371/journal.pone.0172531</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28278267">pmid:28278267</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5344349/">pmcid:PMC5344349</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/sn63v26k7rcxrglcjsraeuawhy">fatcat:sn63v26k7rcxrglcjsraeuawhy</a> </span>
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Dynamics of large-scale fMRI networks: Deconstruct brain activity to build better models of brain function

Fikret Işık Karahanoğlu, Dimitri Van De Ville
<span title="">2017</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/vvrjcjsarbb53fere4crr35dge" style="color: black;">Current Opinion in Biomedical Engineering</a> </i> &nbsp;
D: On spurious and real fluctuations of dynamic functional connectivity during rest.  ...  measures of functional connectivity.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.cobme.2017.09.008">doi:10.1016/j.cobme.2017.09.008</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/oo4evu6w2jgtvbithzy3emlyny">fatcat:oo4evu6w2jgtvbithzy3emlyny</a> </span>
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Spatial Bayesian GLM on the cortical surface produces reliable task activations in individuals and groups [article]

Daniel Spencer, Yu Yue, David Bolin, Sarah Ryan, Amanda F. Mejia
<span title="2021-10-27">2021</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
The general linear model (GLM) is a widely popular and convenient tool for estimating the functional brain response and identifying areas of significant activation during a task or stimulus.  ...  A recent alternative, a cortical surface-based spatial Bayesian GLM, leverages spatial dependencies among neighboring cortical vertices to produce more accurate estimates and areas of functional activation  ...  Acknowledgments The research of Daniel Spencer and Amanda Mejia is partially funded by the National Institute of Biomedical Imaging and Bioengineering (R01EB027119).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/2106.06669v3">arXiv:2106.06669v3</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/q4cxkm6emfbdnabnwoli3vduim">fatcat:q4cxkm6emfbdnabnwoli3vduim</a> </span>
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Intrinsic Functional Connectivity As a Tool For Human Connectomics: Theory, Properties, and Optimization

Koene R. A. Van Dijk, Trey Hedden, Archana Venkataraman, Karleyton C. Evans, Sara W. Lazar, Randy L. Buckner
<span title="">2010</span> <i title="American Physiological Society"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/nr2f6gixzrgdlloxlemhfdztdi" style="color: black;">Journal of Neurophysiology</a> </i> &nbsp;
Activity and connectivity of brain mood regulating circuit in depression: a functional magnetic resonance study. Biol Psychiatry 57: 1079 -1088, 2005.  ...  Neuroimage 31: 1536 -1548, 2006. 317 INTRINSIC FUNCTIONAL CONNECTIVITY The effect of respiration variations on independent component analysis results of resting state functional connectivity.  ...  Effect of task on functional connectivity To explore the influence of the task on fcMRI analysis, datasets 3-5 systematically varied the task across functional runs.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1152/jn.00783.2009">doi:10.1152/jn.00783.2009</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/19889849">pmid:19889849</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC2807224/">pmcid:PMC2807224</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ygqtjzyesfbkfjft7i72g263we">fatcat:ygqtjzyesfbkfjft7i72g263we</a> </span>
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Task-based dynamic functional connectivity: Recent findings and open questions

Javier Gonzalez-Castillo, Peter A. Bandettini
<span title="">2018</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
The temporal evolution of functional connectivity (FC) within the confines of individual scans is nowadays often explored with functional neuroimaging.  ...  FC does reconfigure in systematic ways to accommodate task demands.  ...  Acknowledgments This research was possible thanks to the support of the National Institute of Mental Health Intramural Research Program (NIH clinical protocol number NCT00001360, protocol ID 93-M-0170,  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2017.08.006">doi:10.1016/j.neuroimage.2017.08.006</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28780401">pmid:28780401</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5797523/">pmcid:PMC5797523</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/mwiaoo6fdbfbfnk6be2nfw32om">fatcat:mwiaoo6fdbfbfnk6be2nfw32om</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200209064037/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5797523&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/f4/cf/f4cf2b1012a3b8d2604bb95d5bc328792cb76a29.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2017.08.006"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797523" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Top–Down Modulation from Inferior Frontal Junction to FEFs and Intraparietal Sulcus during Short-term Memory for Visual Features

Markus H. Sneve, Svein Magnussen, Dag Alnæs, Tor Endestad, Mark D'Esposito
<span title="">2013</span> <i title="MIT Press - Journals"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/rvtepewc6vewtddjhxdnivd43q" style="color: black;">Journal of Cognitive Neuroscience</a> </i> &nbsp;
In the present fMRI study, we investigated effective connectivity between central nodes in this network during the different task epochs of a modified delayed orientation discrimination task.  ...  We also investigated a set of control conditions involving active processing of stimuli not associated with a memory task and passive viewing.  ...  This work was supported by a grant from the University of Oslo to the Center for the Study of Human Cognition.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1162/jocn_a_00426">doi:10.1162/jocn_a_00426</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23691986">pmid:23691986</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/mkfq254q6nfvbn7c44znwuhs7a">fatcat:mkfq254q6nfvbn7c44znwuhs7a</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210324065133/https://watermark.silverchair.com/jocn_a_00426.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAp8wggKbBgkqhkiG9w0BBwagggKMMIICiAIBADCCAoEGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMsCnX4BllLlRTiXIMAgEQgIICUgjV0AfjPqv4t2r8GtpwFMUZ1te0-mECZkwBHzI4ejW5DwgHWCY0QNlZFfHU3fWmECyraEWRJ7_lWyKb1iAx2PL45tRAWsOuGsOeeDeXOtFbHZ1yQ0zBE4YC4IbAom8MlfaKgfN_34a5sDSmy1n0lqUGDQRZAPYTDS1Pke7QPA43bjHxQGQNOpyyDhdxRyM0c53V3h4xSJw2lsvtZVrIAFZWmdigMQdGqAW_geHDWssZ4RSeD2NMaDW8BTF8me4SVPKPsgqTHJirppRBe2bBcrR1-eEfsjijzE2rJigL46oEwB0aK6VojKs4wsxdqhbXK7Cfz585IAKd-G1dwezaMd17ipn7I4RekSFtC9I7myU37EGUXy_M5He9fMSBLrwFbJG4f1oSd8EXC-tkjlc513S2q2Srd-lhTJskZDEdiVryVb9rAQMYeQ60QGyqa7aYYuMLQEE6be4gUHh0cbfFsk4VBpYZnpCX1cnGdX9t3BgCF07L_ch3MyusPCJAiSPDcPdP9VHLis7ZYeipCcMZGdmXQ4QiSempZ5r7-rF5-UESGI1bIn1xZBhQ3E1PeYR05d7O9DhvGCYItPRnAYT3c7AKUij4sh0pwXbee3Kc6EQSxLuwbquIGZuYMqMz7goqt6K_M29eOa1Bw3sFBxf8EF-VfOoH-mypuAy_tedpcwGKi8meesDgB_DW4570H8-9lADEKNR2Wjg_U2ODG3iSBgc3K3QJm_22NZo5KHtnT_-NQ0R9vr-vxsI_HpqEYnmbrTVR3q7jfmqJQQCMYx9F8pl8Sw" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/dd/53/dd53e1a62742d557334e25c3f9d400ba4c11ea3f.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1162/jocn_a_00426"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> mitpressjournals.org </button> </a>

Ghost interactions in MEG/EEG source space: A note of caution on inter-areal coupling measures

J. Matias Palva, Sheng H. Wang, Satu Palva, Alexander Zhigalov, Simo Monto, Matthew J. Brookes, Jan-Mathijs Schoffelen, Karim Jerbi
<span title="">2018</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
To overcome the inflating effects of linear source mixing inherent to standard interaction measures, alternative phase-and amplitude-correlation based connectivity measures, such as imaginary coherence  ...  We show here, however, that while these measures are immune to the direct effects of linear mixing, they may still reveal large numbers of spurious false positive connections through field spread in the  ...  Acknowledgments This study was supported by the Academy of Finland Grants 253130 and 256472 to J.M.P. and 1126967 to S.P., and by the Helsinki University Research Funds.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2018.02.032">doi:10.1016/j.neuroimage.2018.02.032</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29477441">pmid:29477441</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/4peo65vlpzautli7gwhlb6xe4u">fatcat:4peo65vlpzautli7gwhlb6xe4u</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180719201145/https://helda.helsinki.fi/bitstream/handle/10138/234709/Ghost_interactions_in_MEG_EEG_source_space.pdf;jsessionid=07EF23E07515E7AA2DF9FF025764F864?sequence=1" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/da/d5/dad5876542dcd14d8070928d578083ef9bf0265b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2018.02.032"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a>

Ghost interactions in MEG/EEG source space: A note of caution on inter-areal coupling measures [article]

J. Matias Palva, Sheng H. Wang, Satu Palva, Alexander Zhigalov, Simo Monto, Matthew J. Brookes, Jan-Mathijs Schoffelen, Karim Jerbi
<span title="2017-11-16">2017</span> <i title="Cold Spring Harbor Laboratory"> biorxiv/medrxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
To overcome the inflating effects of linear source mixing inherent to standard interaction measures, alternative phase- and amplitude-correlation based connectivity measures, such as imaginary coherence  ...  We show here, however, that while these measures are immune to the direct effects of linear mixing, they may still reveal large numbers of spurious false positive connections through field spread in the  ...  Acknowledgments This study was supported by the Academy of Finland Grants 253130 and 256472 to J.M.P. and 1126967 to S.P., and by the Helsinki University Research Funds.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/220459">doi:10.1101/220459</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/gk3llphcmvam5f6p32zpod7uhq">fatcat:gk3llphcmvam5f6p32zpod7uhq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200311150912/https://pure.mpg.de/rest/items/item_3159071_2/component/file_3159072/content" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/84/71/8471eca29ad849848a3a91fb3c26ab989f07508b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/220459"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

Task-evoked activity quenches neural correlations and variability in large-scale brain systems [article]

Takuya Ito, Scott L Brincat, Markus Siegel, Ravi D Mill, Biyu J He, Earl K Miller, Horacio G Rotstein, Michael W Cole
<span title="2019-02-25">2019</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Many studies of large-scale neural systems have emphasized the importance of communication through increased inter-region correlations ("functional connectivity") during task states relative to resting  ...  Together, our results provide an integrative mechanistic account that encompasses measures of large-scale neural activity, variability, and correlations during resting and task states.  ...  To further complicate this issue, we recently found that task activations can inflate task functional connectivity estimates in human fMRI data (24) , suggesting some previous neuroimaging studies may  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/560730">doi:10.1101/560730</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/nrpzbrzktja25mrn3dl4rx5su4">fatcat:nrpzbrzktja25mrn3dl4rx5su4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190427220259/https://www.biorxiv.org/content/biorxiv/early/2019/02/25/560730.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/02/cc/02ccfd87cefab648536e430f3ef319c1d877e6e1.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/560730"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>
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