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C-MAC Video Laryngoscope versus Conventional Direct Laryngoscopy for Endotracheal Intubation During Cardiopulmonary Resuscitation
2019
Medicina
and objectives: To compare the first pass success (FPS) rate of the C-MAC video laryngoscope (C-MAC) and conventional Macintosh-type direct laryngoscopy (DL) during cardiopulmonary resuscitation (CPR) in the emergency department (ED). Materials and Methods: This study was a single-center, retrospective study conducted from April 2014 to July 2018. Patients were categorized into either the C-MAC or DL group, according to the device used on the first endotracheal intubation (ETI) attempt. The
doi:10.3390/medicina55060225
pmid:31146497
pmcid:PMC6631212
fatcat:z3ygmtw62ncxbmf6mnuovskfpa
more »
... ary outcome was the FPS rate. A multiple logistic regression model was developed to identify factors related to the FPS. Results: A total of 573 ETIs were performed. Of the eligible cases, 263 and 310 patients were assigned to the C-MAC and DL group, respectively. The overall FPS rate was 75% (n = 431/573). The FPS rate was higher in the C-MAC group than in the DL group, but there was no statistically significant difference (total n = 431, 79% compared to 72%, p = 0.075). In the multiple logistic regression analysis, the C-MAC use had higher FPS rate (adjusted odds ratio: 1.80; 95% CI, 1.17–2.77; p = 0.007) than that of the DL use. Conclusions: The C-MAC use on the first ETI attempt during cardiopulmonary resuscitation in the emergency department had a higher FPS rate than that of the DL use.
Assessment of intratumoral heterogeneity with mutations and gene expression profiles
2019
PLoS ONE
Author Contributions Conceptualization: Hyun-Tae Shin, Je-Gun Joung. ...
doi:10.1371/journal.pone.0219682
pmid:31310640
pmcid:PMC6634409
fatcat:hhecmoqr4rhvnclljvpqusgo2a
A Case ofChlamydia trachomatisPeritonitis Mimicking Tuberculous Peritonitis
2011
Korean Journal of Gastroenterology
Lymphocytic ascites with low serum-ascites albumin gradient (SAAG) are observed mainly in tuberculous peritonitis, peritoneal carcinomatosis, and pancreatic disease. However, pelvic inflammatory disease (PID) induced generalized peritonitis causing diffuse ascites has been rarely described. We report a 26-year old female patient, who was diagnosed as generalized peritonitis with diffuse ascites due to Chlamydia trachomatis infection. Gynecologic examination did not show the clue of PID and in
doi:10.4166/kjg.2011.58.2.111
pmid:21873828
fatcat:3qjqkay6cfewlf26vxwdbtpfnq
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... e analysis of ascites, low SAAG, predominant lymphocyte count and high level of adenosine deaminase were noted. Although the best impression was tuberculous peritonitis on the base of these findings, the laparoscopic finding was consistent with PID and the PCR for C. trachomatis infection in cervical swab was positive. This case suggests that C. trachomatis peritonitis should be considered as a rare cause of low SAAG and lymphocytic ascites in sexually active women and should be intensively evaluated including laparoscopic examination. (Korean J Gastroenterol 2011;58:111-116)
Ketamine use for endotracheal intubation in severe sepsis and septic shock
2018
Signa Vitae
Objective. We conducted this study to evaluate the clinical outcomes of patients with severe sepsis and septic shock who were treated with ketamine for endotracheal intubation. Methods. A single-center, retrospective study was carried out to compare the outcomes of patients with severe sepsis and septic shock who received a ketamine or non-ketamine agent for rapid sequence intubation (RSI). We analyzed the sepsis registry for adult patients who presented to the emergency department (ED), met
doi:10.22514/sv142.102018.3
fatcat:vdevikrvxvg27pruztjxz6mkz4
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... criteria for severe sepsis or septic shock, and underwent endotracheal intubation between August 2008 and March 2014. The primary outcome was 28-day mortality. We performed a multivariable logistic regression analysis to assess the association between ketamine use for intubation and 28-day mortality. Results. In all, 170 patients were intubated during the study period. Of the eligible patients, 95 received ketamine and 75 received a non-ketamine agent. The 28-day mortality of the ketamine group was not significantly different from that of the nonketamine group (38% vs. 40%, respectively, P=0.78). The unadjusted odds ratio (OR) of ketamine use for 28-day mortality was 0.92 (95% CI: 0.49-1.70, P=0.78). The association remained insignificant after adjusting for age, gender, malignancy, initial lactate level on ED admission, time to first antibiotic administration, Acute Physiology and Chronic Health Evaluation II score on admission day, and propensity score regarding ketamine use (adjusted OR: 1.09; 95% confidence interval [CI]: 0.49-2.40; P=0.84). Initial serum lactate on ED admission was the only significant predictive factor of 28-day mortality (adjusted OR: 1.23; 95% CI: 1.10-1.38; P<0.01). Conclusions. For patients with severe sepsis and septic shock who were intubated using RSI, we found no significant difference in 28-day mortality between those who received ketamine as a sedative agent and those who received alternative sedatives.
The Psychological Effects of a Campus Forest Therapy Program
2020
International Journal of Environmental Research and Public Health
For the office workers, Shin et al. [33] reported that the two-day forest therapy program provided significantly positive changes in workers' job stress and moods. ...
For example, Lee and Shin [35] reported that the forest therapy program, performed at a university campus forest using university students, provided significantly positive emotional improvement. ...
doi:10.3390/ijerph17103409
pmid:32422871
fatcat:c3zjd5irtzh5bgn6ot6xbxwqzi
Finger necrosis after accidental radial artery puncture
2014
Clinical and Experimental Emergency Medicine
Radial artery puncture, an invasive procedure, is frequently used for critical patients. Although considered safe, severe complications such as finger necrosis can occur. Herein, we review the clinical course of finger necrosis after accidental radial artery puncture. A 63-year-old woman visited the emergency department (ED) with left second and third finger pain after undergoing intravenous (IV) access in her wrist for procedural sedation. During the IV access, she experienced wrist pain,
doi:10.15441/ceem.14.045
pmid:27752565
pmcid:PMC5052832
fatcat:kmowwxnehzddxfuhgewt7qegsy
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... increased during the 12 hours prior to her ED presentation. Emergency angiography revealed a pseudoaneurysm in her left radial artery and absence of blood flow to the proper palmar digital artery. Subsequent angiointervention and urokinase thrombolysis failed. The second finger was eventually amputated owing to gangrene. Radial artery puncture can occur accidentally during IV wrist access, resulting in severe morbidity. Providers should carefully examine the puncture site and collateral flow, followed by multiple examinations to ensure distal circulation. Clin Exp Emerg Med 2014;1(2):130-133 http://dx.
Impact of Personal Protective Equipment on Out-of-Hospital Cardiac Arrest Resuscitation in Coronavirus Pandemic
2021
Medicina
and Objectives: This retrospective study evaluated the clinical impact of enhanced personal protective equipment (PPE) on the clinical outcomes in patients with out-of-hospital cardiac arrest. Moreover, by focusing on the use of a powered air-purifying respirator (PAPR), we investigated the medical personnel's perceptions of wearing PAPR during cardiopulmonary resuscitation. Materials and Methods: According to the arrival time at the emergency department, the patients were categorized into a
doi:10.3390/medicina57121291
pmid:34946236
pmcid:PMC8708039
fatcat:mr66hs2u75gb7pd4ibmce6yyx4
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... ventional PPE group (1 August 2019 to 20 January 2020) and an enhanced PPE group (21 January 2020, to 31 August 2020). The primary outcomes of this analysis were the return of spontaneous circulation (ROSC) rate. Additionally, subjective perception of the medical staff regarding the effect of wearing enhanced PPE during cardiopulmonary resuscitation (CPR) was evaluated by conducting a survey. Results: This study included 130 out-of-hospital cardiac arrest (OHCA) patients, with 73 and 57 patients in the conventional and enhanced PPE groups, respectively. The median time intervals to first intubation and to report the first arterial blood gas analysis results were longer in the enhanced PPE group than in the conventional PPE group (3 min vs. 2 min; p = 0.020 and 8 min vs. 3 min; p < 0.001, respectively). However, there were no significant differences in the ROSC rate (odds ratio (OR) = 0.79, 95% confidence interval (CI): 0.38–1.67; p = 0.542) and 1 month survival (OR 0.38, 95% CI: 0.07–2.10; p = 0.266) between the two groups. In total, 67 emergent department (ED) professionals responded to the questionnaire. Although a significant number of respondents experienced inconveniences with PAPR use, they agreed that PAPR was necessary during the CPR procedure for protection and reduction of infection transmission. Conclusion: The use of enhanced PPE, including PAPR, affected the performance of CPR to some extent but did not alter patient outcomes. PAPR use during the resuscitation of OHCA patients might positively impact the psychological stability of the medical staff.
Epidemiology and Outcome of Powered Mobility Device-Related Injuries in Korea
2020
Journal of Korean medical science
Conceptualization: Shin Y, Cha WC, Kim T. Data curation: Shin Y, Yoon H, Hwang SY, Shin TG. Formal analysis: Kim T. Methodology: Cha WC. Resources: Shin TG, Sim MS, Jo IS. ...
Writing -original draft: Shin Y. Writing -review & editing: Kim T.
Fig. 2 . 2 Study selection graph for PMD-related injuries. ...
doi:10.3346/jkms.2020.35.e60
pmid:32141250
pmcid:PMC7061147
fatcat:jzzc7w6axnfdpilmrpoje77fii
Extracting regulatory modules from gene expression data by sequential pattern mining
2011
BMC Genomics
Identifying a regulatory module (RM), a bi-set of co-regulated genes and co-regulating conditions (or samples), has been an important challenge in functional genomics and bioinformatics. Given a microarray geneexpression matrix, biclustering has been the most common method for extracting RMs. Among biclustering methods, order-preserving biclustering by a sequential pattern mining technique has native advantage over the conventional biclustering approaches since it preserves the order of genes
doi:10.1186/1471-2164-12-s3-s5
pmid:22369275
pmcid:PMC3333188
fatcat:lrhcqct5gvf2xarqxwqaluckxm
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... r conditions) according to the magnitude of the expression value. However, previous sequential pattern mining-based biclustering has several weak points in that they can easily be computationally intractable in the real-size of microarray data and sensitive to inherent noise in the expression value.
Accuracy of the qSOFA Score and RED Sign in Predicting Critical Care Requirements in Patients with Suspected Infection in the Emergency Department: A Retrospective Observational Study
2020
Medicina
and objectives: We aimed to compare the accuracy of positive quick sequential organ failure assessment (qSOFA) scores and the RED sign in predicting critical care requirements (CCRs) in patients with suspected infection who presented to the emergency department (ED). Materials and Methods: In this retrospective observational study, we examined adult patients with suspected infection in the ED from June 2018 to September 2018. A positive qSOFA (qSOFA+) was defined as the presence of ≥2 of the
doi:10.3390/medicina56010042
pmid:31963955
pmcid:PMC7022561
fatcat:7wef4ha5zjgcrfevjaep3fwdmu
more »
... lowing criteria: altered mental status (AMS), systolic blood pressure (SBP) < 100 mmHg, and respiratory rate (RR) ≥ 22 breaths/min. A positive RED sign (RED sign+) was defined as the presence of at least one of the RED sign criteria: AMS, skin mottling, SBP < 90 mmHg, heart rate >130 beats/min, or RR > 30 breaths/min. A qSOFA/RED+ was defined as the presence of qSOFA+ or RED+. We applied these tools twice using the initial values upon ED arrival and all values within 2 h after ED arrival. The accuracy of qSOFA+, RED+, and qSOFA/RED+ in predicting CCR was assessed. Results: Data from 5353 patients with suspected infection were analyzed. The area under the receiver operating characteristic curve (AUC) of RED+ (0.67, 95% confidence interval [CI]: 0.65–0.70) and that of qSOFA/RED+ (0.68, 95% CI: 0.66–0.70, p < 0.01) were higher than the AUC of qSOFA+ (0.59, 95% CI: 0.57–0.60) in predicting CCR on ED arrival. The qSOFA/RED+ within 2 h showed the highest accuracy (AUC 0.72, 95% CI: 0.70–0.75, p < 0.001). Conclusions: The accuracy of the RED sign in predicting CCR in patients with suspected infection who presented at ED was better than that of qSOFA. The combined use of the RED sign and qSOFA (positive qSOFA or RED sign) showed the highest accuracy.
Effect of typhoons on the Korean national emergency medical service system
2018
Clinical and Experimental Emergency Medicine
While the effect of typhoons on emergency medicine has been evaluated, data are scarce on their effects on the emergency medical service (EMS). This study evaluated the effect of typhoons on EMS patients and performance. The study period was January 2010 to December 2012. Meteorological data regarding typhoons were provided by the Korean Meteorological Administration. EMS data were retrieved from the EMS database of the national emergency management agency. The database includes ambulance run
doi:10.15441/ceem.17.255
pmid:30571906
pmcid:PMC6301860
fatcat:ej54jdr5k5f57a4cfkmxygtxvy
more »
... eets, which contain clinical and operational data. In this case-crossover study, the cases and controls were EMS calls on the day of typhoon warnings and calls one week prior to the typhoon warnings, respectively. During the study period, 11 typhoons affected Korea. A total of 14,521 cases were selected for analysis. Overall, there were no obvious differences between the case and control groups. However, there were statistically significant differences in age, place, and time requests. There were fewer patients between 0 and 15 years of age (P=0.01) and more unconscious patients (P=0.01) in the case group. The EMS operational performance, as measured by the times elapsed between call to start, call to field, and call to hospital did not differ significantly. There was also no significant difference in the time from hospital arrival between the cases (28.67, standard deviation 16.37) and controls (28.97, standard deviation 28.91) (P=0.39). Typhoons did not significantly affect the EMS system in this study. Further study is necessary to understand the reasons for this finding.
Epidemiological study of clonorchiasis and metagonimiasis along the Geum-gang (River) in Okcheon-gun (County), Korea
2002
Korean Journal of Parasitology
DISCUSSION Okcheon-gun lies in the Geum-gang (River) basin in Chungcheongbuk-do, Korea. ...
In this study, C. sinensis-positive cases were given 3x25 mg/kg in one day at the Okcheon-gun Public Health Center. ...
doi:10.3347/kjp.2002.40.1.9
pmid:11949215
pmcid:PMC2721058
fatcat:oyqzut2nuzeexlpt23gvidkgue
Coronary angiography is related to improved clinical outcome of out-of-hospital cardiac arrest with initial non-shockable rhythm
2017
PLoS ONE
Objective Coronary angiography (CAG) for survivors of out-of-hospital cardiac arrest (OHCA) enables early identification of coronary artery disease and revascularization, which might improve clinical outcome. However, little is known for the role of CAG in patients with initial nonshockable cardiac rhythm. Methods We investigated clinical outcomes of successfully resuscitated 670 adult OHCA patients who were transferred to 27 hospitals in Cardiac Arrest Pursuit Trial with Unique Registration
doi:10.1371/journal.pone.0189442
pmid:29287074
pmcid:PMC5747431
fatcat:tm6pxzn6sjep7er3rag7rlvo5m
more »
... Epidemiologic Surveillance (CAPTURES), a Korean nationwide multicenter registry. The primary outcome was 30-day survival with good neurological outcome. Propensity score matching and inverse probability of treatment weighting analyses were performed to account for indication bias. Results A total of 401 (60%) patients showed initial non-shockable rhythm. CAG was performed only in 13% of patients with non-shockable rhythm (53 out of 401 patients), whereas more than half of patients with shockable rhythm (149 out of 269 patients, 55%). Clinical outcome of patients who underwent CAG was superior to patients without CAG in both non-shockable (hazard ratio (HR) = 3.6, 95% confidence interval (CI) = 2.5-5.2) and shockable rhythm (HR = 3.7, 95% CI = 2.5-5.4, p < 0.001, all). Further analysis after propensity score matching or inverse probability of treatment weighting showed consistent findings (HR ranged from 2.0 to 3.2, p < 0.001, all).
Inhibition of Herpesvirus-6B RNA Replication by Short Interference RNAs
2004
BMB Reports
RNA interference (RNAi) is a process of sequence-specific gene silencing, which is initiated by double-stranded RNA (dsRNA). RNAi may also serve as an antiviral system in vertebrates. This study describes the inhibition of herpesvirus-6B (HHV-6B) replication by short interference RNAs (siRNAs) that are targeted to the U38 sequence that encodes DNA polymerase. When virusinfected SupT1 cells were treated by siRNA, these cells blocked the cytopathic effect (CPE) and detected the HHV-6B
doi:10.5483/bmbrep.2004.37.3.383
pmid:15469723
fatcat:pssby2v56faa7pnrbwrpk7dibi
more »
... ative in indirect immunofluorescence assays (IFA). Our result suggests that RNAi can efficiently block Herpesvirus-6B replication.
Posterolateral Fusion for Unstable Thoracolumbar Junction
2003
Journal of Korean Society of Spine Surgery
후방도달 04) Bradford DS and Mcbride GG : Surgical management 술을 통한 단분절 유합술로도 좋은 결과를 얻을 수 있다 Shin JH and Na CO : Survival analysis of posterior short 추체간유합술은 척수원추를 손상시킬 위험성이 많아서 of thoracolumbar spine fractures ...
doi:10.4184/jkss.2003.10.2.90
fatcat:6q7yt24mavgdjmcaqjg5zt7j3i
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