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The heptamer sgRNA targeting the human OCT4 mRNA can upregulate the OCT4 expression

Tadasuke Nozaki, Masayuki Takahashi, Tatsuya Ishikawa, Arisa Haino, Mineaki Seki, Hidetomo Kikuchi, Bo Yuan, Masayuki Nashimoto
2021 Biochemistry and Biophysics Reports  
CRediT authorship contribution statement Tadasuke Nozaki: Conceptualization, Investigation, Writing -review & editing. Masayuki Takahashi: Investigation, Methodology, Writing -review & editing.  ... 
doi:10.1016/j.bbrep.2021.100918 pmid:33553691 pmcid:PMC7859166 fatcat:fxebfqh4hzfs7o7qeaizlavqwe

Search for the Magnetic Monopole at a Magnetoelectric Surface

Quintin N. Meier, Michael Fechner, Tadasuke Nozaki, Masashi Sahashi, Zaher Salman, Thomas Prokscha, Andreas Suter, Peggy Schoenherr, Martin Lilienblum, Pavel Borisov, Igor E. Dzyaloshinskii, Manfred Fiebig (+2 others)
2019
We show, by solving Maxwell's equations, that an electric charge on the surface of a slab of a linear magnetoelectric material generates an image magnetic monopole below the surface provided that the magnetoelectric has a diagonal component in its magnetoelectric response. The image monopole, in turn, generates an ideal monopolar magnetic field outside of the slab. Using realistic values of the electric and magnetic field susceptibilities, we calculate the magnitude of the effect for the
more » ... pical magnetoelectric material Cr 2 O 3 . We use low-energy muon spin rotation to measure the strength of the magnetic field generated by charged muons as a function of their distance from the surface of a Cr 2 O 3 film and show that the results are consistent with the existence of the monopole. We discuss other possible routes to detecting the monopolar field, and show that, while the predicted monopolar field generated by Cr 2 O 3 is above the detection limit for standard magnetic force microscopy, the detection of the field using this technique is prevented by surface charging effects.
doi:10.3929/ethz-b-000321160 fatcat:evs3ucraj5glho5sl5v2by2wtq

FANTOM5 CAGE profiles of human and mouse samples

Shuhei Noguchi, Takahiro Arakawa, Shiro Fukuda, Masaaki Furuno, Akira Hasegawa, Fumi Hori, Sachi Ishikawa-Kato, Kaoru Kaida, Ai Kaiho, Mutsumi Kanamori-Katayama, Tsugumi Kawashima, Miki Kojima (+166 others)
2017 Scientific Data  
In the FANTOM5 project, transcription initiation events across the human and mouse genomes were mapped at a single base-pair resolution and their frequencies were monitored by CAGE (Cap Analysis of Gene Expression) coupled with single-molecule sequencing. Approximately three thousands of samples, consisting of a variety of primary cells, tissues, cell lines, and time series samples during cell activation and development, were subjected to a uniform pipeline of CAGE data production. The analysis
more » ... pipeline started by measuring RNA extracts to assess their quality, and continued to CAGE library production by using a robotic or a manual workflow, single molecule sequencing, and computational processing to generate frequencies of transcription initiation. Resulting data represents the consequence of transcriptional regulation in each analyzed state of mammalian cells. Non-overlapping peaks over the CAGE profiles, approximately 200,000 and 150,000 peaks for the human and mouse genomes, were identified and annotated to provide precise location of known promoters as well as novel ones, and to quantify their activities.
doi:10.1038/sdata.2017.112 pmid:28850106 pmcid:PMC5574368 fatcat:cel5hhhtardinak67mbl2okvhe

Index

2022 Nippon Saikingaku Zasshi  
Shinji Ozeki, Yuriko 〃 Tsukuda, Naoki Zhang, Tianli 木村 幸司 馬渡 一諭 中岡 慎治 尾関 百合子 佃 直紀 張 田力 ODP-131 W5-4/ODP-076 ODP-048 WCB-3 S9-2 ODP-215 W4-3 W10-6/ODP-213 〃 Ishibashi, Masami Konno, Ayano Mori, Taiki Nozaki  ...  , Seiya Izumiya, Hidemasa 〃 Murai, Miyo 〃 〃 Tanaka, Yuka 〃 原田 誠也 泉谷 秀昌 村井 美代 田中 佑佳 W7-3 ODP-073 ODP-119 ODP-010 ODP-116 ODP-207 ODP-027 ODP-026 Hirayama, Satoru Kawai, Noriaki 〃 Nakamura, Mineo Ooka, Tadasuke  ... 
doi:10.3412/jsb.77.120 pmid:35185070 fatcat:wykuirx5bnegxk3lick72xaqj4

On-demand Presentation

2022 Nippon Saikingaku Zasshi  
動衛研・細菌・寄生虫) Intra-Macrophage Expression of ArtAB Toxin Gene in Salmonella ○Rin Satoh 1 , Ikuo Uchida 1 , Shou Miura 1 , Ryo Murata 1 , Yukino Tamamura 2 , Kanetaka Tokugawa 1 , Miho Beppu 1 , Chiharu Nozaki  ...  哲也 4 ,岡本 康裕 1 ,西 順一郎 1 ( 1 鹿児島大・医歯 学, 2 感染研・危機管理研究センター, 3 国衛研・衛生微生物, 4 九州大・ 医・細菌学, 5 久留米大・医・感染) Diversification of Escherichia albertii H-Antigens and Development of H-Genotyping PCR ○Koji Nakae 1 , Tadasuke  ... 
doi:10.3412/jsb.77.58 pmid:35185075 fatcat:eulr5inwjfd4blqkzhuokpdhey