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Trends in 3D Printing Processes for Biomedical Field: Opportunities and Challenges

Alina Ghilan, Aurica P. Chiriac, Loredana E. Nita, Alina G. Rusu, Iordana Neamtu, Vlad Mihai Chiriac
2020 Journal of polymers and the environment  
The basic requirements for the selection of successful inks based on polymers, polymer blends, and composites are described.  ...  Machine learning can improve printing efficiency by using generative design and testing in the pre-fabrication stage. Finally, important limitations and prospects are identified.  ...  hydrogels as therapeutic delivery systems for skin tissue remodeling", within PNCDI III.  ... 
doi:10.1007/s10924-020-01722-x pmid:32435165 pmcid:PMC7224028 fatcat:qsuzj22jqbdldputpuqbyv6jou

Extrusion and Microfluidic‐Based Bioprinting to Fabricate Biomimetic Tissues and Organs

Elham Davoodi, Einollah Sarikhani, Hossein Montazerian, Samad Ahadian, Marco Costantini, Wojciech Swieszkowski, Stephanie Michelle Willerth, Konrad Walus, Mohammad Mofidfar, Ehsan Toyserkani, Ali Khademhosseini, Nureddin Ashammakhi
2020 Advanced Materials Technologies  
To circumvent the downsides associated with extrusion printing, microfluidic technologies are increasingly being implemented in 3D bioprinting for engineering living constructs.  ...  Microfluiding bioprinting technology enables highly controlled fabrication of 3D constructs in high resolutions and it has been shown to be useful for building tubular structures and vascularized constructs  ...  They suggested that nanofibers can be used to reinforce the channels and improve their mechanical properties.  ... 
doi:10.1002/admt.201901044 pmid:33072855 pmcid:PMC7567134 fatcat:j66nsaoqtvaf3p24mfps2isaua

Combination of Stem Cells and Rehabilitation Therapies for Ischemic Stroke

Reed Berlet, Stefan Anthony, Beverly Brooks, Zhen-Jie Wang, Nadia Sadanandan, Alex Shear, Blaise Cozene, Bella Gonzales-Portillo, Blake Parsons, Felipe Esparza Salazar, Alma R. Lezama Toledo, Germán Rivera Monroy (+2 others)
2021 Biomolecules  
Here, we discuss current breakthroughs in stem cell research along with rehabilitation strategies that may have a synergistic outcome when combined together after stroke.  ...  pathophysiology of stroke and the mechanisms by which stem cells and rehabilitation attenuate this inflammatory process, we hypothesize that a combined therapy will provide better functional outcomes for  ...  How Does VR-Based Rehabilitation Improve Functional Recovery?  ... 
doi:10.3390/biom11091316 pmid:34572529 pmcid:PMC8468342 fatcat:2eoqircssbcf7gkbe6cufh7umi

Biomimetic Architectures for Tissue Engineering [chapter]

Jianming Li, Sean Connell, Riyi Shi
2010 Biomimetics Learning from Nature  
Acknowledgments We would like to thank Michel Schweinsberg for his contributions in artwork. References  ...  Incorporating such compounds synergistically within the material architecture is critical for optimum success.  ...  The outmost wall consists of fibroblasts embedded within a randomly aligned collagen type I matrix for structural support.  ... 
doi:10.5772/8773 fatcat:tqnnehg7offnvne2nistkkjjhi

Cutting-Edge Progress in Stimuli-Responsive Bioadhesives: From Synthesis to Clinical Applications

Elham Khadem, Mahshid Kharaziha, Hamid Reza Bakhsheshi-Rad, Oisik Das, Filippo Berto
2022 Polymers  
With the advent of "intelligent" materials, the design of smart bioadhesives responding to chemical, physical, or biological stimuli has been widely developed in biomedical applications to minimize the  ...  Intelligent bioadhesives are free-flowing liquid solutions passing through a phase shift in the physiological environment due to stimuli such as light, temperature, pH, and electric field.  ...  Based on the results, an optimal thickness of 13 up to 18 nm was recognized for maximizing microorganism detachment on the PAA brushes at pH 4. The brush dispersion did not affect bacterial adhesion.  ... 
doi:10.3390/polym14091709 pmid:35566878 pmcid:PMC9104595 fatcat:jiob4lmwdnhonpmr5xzxtnxuru

46th ESAO Congress 3–7 September 2019 Hannover, Germany

2019 International Journal of Artificial Organs  
Biomechanical modeling allows for patientspecific outcome prediction after surgical interventions and should become a routine practice in patient treatment.  ...  Patient specific surgical instrumentation is able to assist in realising the plan with sub-millimeter precision.  ...  Active and Composite Biomaterials P231 THE STUDY OF BIOLOGICAL LASER SOLDERS BASED ON BOVINE SERUM ALBUMIN AND SINGLE-WALL CARBON NANOTUBES USING DYNAMIC SCANNING CALORIMETRY METOD Acknowledgements  ... 
doi:10.1177/0391398819860985 fatcat:s5xpxxvq2fhtdacxuf5iw6n3z4

2011 Sino-American Symposium on Clinical and Translational Medicine

S. Sanders
2011 Science  
Michael Silver for his great editorial support, and the Bionest Partners team for contributions to content discussions and the graphics.  ...  A core group of faculty worked as a team to develop learning objectives and create synergistic curricular components to reinforce learning across multiple domains.  ...  Based on the success of synergistic targeted therapies for APL, it is Translational Medicine for Myeloid Leukemia Sai-Juan Chen, M.D.  ... 
doi:10.1126/science.334.6063.1735-c fatcat:bgaizhe3pffoxmaxbfwvwebivq

Nanoarchitectured prototypes of mesoporous silica nanoparticles for innovative biomedical applications

Ranjith Kumar Kankala, Ya-Hui Han, Hong-Ying Xia, Shi-Bin Wang, Ai-Zheng Chen
2022 Journal of Nanobiotechnology  
Then, we provide initiatives taken so far in clinical translation of various silica-based materials and their scope towards clinical translation.  ...  Finally, we summarize the review with interesting perspectives on lessons learned in exploring the biomedical applications of advanced MSNs and further requirements to be explored. Graphical Abstract  ...  cargo TME-activated tumor-[440] deep delivery system for dual-mode imaging and self-reinforcing chemody- namic therapy IR780-based SDT and the [441] CA-based GSH depletion improved cancer ablation This  ... 
doi:10.1186/s12951-022-01315-x pmid:35279150 pmcid:PMC8917689 fatcat:tb6awxtpnnfldk3ouz7pbmsx5a

Kimdaejung Convention Center

2019 2019 IEEE 13th International Conference on Nano/Molecular Medicine & Engineering (NANOMED)  
On the other hand, the limitations of the drug carriers for current chemotherapy were improved.  ...  Hence, the AI-PRS platform can quantitatively determine the optimal drug-dose combination for treating a specific patient or a population of patients.  ...  Pluronic F-127 was used as ink carrier for fabricating the scaffolds. The reinforced nanofibers are uniformly dispersed in the bioactive glass matrix.  ... 
doi:10.1109/nanomed49242.2019.9130603 fatcat:wlmmq4uwyjablibepjnazw4fp4

QSAR without borders

Eugene N. Muratov, Jürgen Bajorath, Robert P. Sheridan, Igor V. Tetko, Dmitry Filimonov, Vladimir Poroikov, Tudor I. Oprea, Igor I. Baskin, Alexandre Varnek, Adrian Roitberg, Olexandr Isayev, Stefano Curtalolo (+7 others)
2020 Chemical Society Reviews  
Materials science properties, based on fundamental principles, are intrinsically suitable for modeling by machine learning.  ...  Several methods have been proposed for multitask QSAR modeling including perturbation theory + machine learning (PTML), 48 inductive learning and multi-objective optimization 49 as applied in proteochemometrics  ... 
doi:10.1039/d0cs00098a pmid:32356548 fatcat:l456rjoqbzgehkqa63uvqrv2gy

Abstracts book of the Anual International Conference of the Romanian Society for Biochemistry and Molecular Biology

Group Author
2019 Journal of Experimental and Molecular Biology  
The issues containes all the abstracts presented as lectures and posters at the Anual International Conference of the Romanian Society for Biochemistry and Molecular Biology, 26-27th September, Iasi, Romania  ...  Furthermore, we used a combined machine learning algorithm for miR targets prediction, and a clustering and topological community detection (CTCD) approach followed by gene ontology analysis to describe  ...  RDI, Contract No.7PFE/16.10.2018 Abstract: In this study, new hybrid scaffolds based on 3D-printed titanium alloy with spongy bone-like architecture filled with porous hydroxyapatite (i.e. which also  ... 
doaj:ddb59a233992453082eeba1bf81d3986 fatcat:tm6sg2npnjbsrazec7mfbq3mde

The Significance and Utilisation of Biomimetic and Bioinspired Strategies in the Field of Biomedical Material Engineering: The Case of Calcium Phosphat—Protein Template Constructs

2020 Materials  
Moreover, the review also presents a description of smart devices including delivery systems and constructs with specific functions.  ...  Particular attention is devoted to the description of individual peptides and proteins that serve as templates for the biomimetic mineralisation of calcium phosphate.  ...  Sci., Prague, CR) for the scanning electron microscopy analysis and Darren Ireland, BA. Cert. Ed. for the language revision of the English manuscript.  ... 
doi:10.3390/ma13020327 pmid:31936830 pmcid:PMC7013803 fatcat:i26l7ytji5gspph7nt4b4dytgq

Mechanical and electrical characterization of CVD-grown graphene transferred on chalcogenide Ge 2 Sb 2 Te 5 layers

G. D'Arrigo, M. Christian, V. Morandi, G. Favaro, C. Bongiorno, A.M. Mio, M. Russo, A. Sitta, M. Calabretta, A. Sciuto, E. Piccinini, L. D'Urso (+1 others)
2018 Carbon  
or carbon fibers, even so far mainly dedicated to the reinforcement of petrochemical based resins, have been reviewed by several authors.  ...  Finally, regarding the reinforcement, the use of natural fibers, eventually pre-treated to improve the interfacial adhesion with the reference hosting matrix, in place of synthetic ones as glass fibers  ...  Two bio-polyesters having diverse elastic (Young's) moduli (soft and hard) were reinforced (0.1-5 wt.%) with various types of expanded graphite nanoplatelets (GnP flakes) [1].  ... 
doi:10.1016/j.carbon.2018.02.046 fatcat:wiqrs5krczgrrahoa7hl2rgtcm

Advancing biomaterials of human origin for tissue engineering

Fa-Ming Chen, Xiaohua Liu
2016 Progress in polymer science  
Biomaterials have played an increasingly prominent role in the success of biomedical devices and in the development of tissue engineering, which seeks to unlock the regenerative potential innate to human  ...  for the design of future biomaterials.  ...  Special thanks go to the anonymous referees for their insight and truly stimulating and valuable remarks on a former version of this manuscript. Dr.  ... 
doi:10.1016/j.progpolymsci.2015.02.004 pmid:27022202 pmcid:PMC4808059 fatcat:lu34ila5rrcixnl47z3bqd56xe

Jubilee Scientific Conference "Medicine of the Future" - 29-31 October 2020 on the occasion of the 75th Anniversary of Medical University of Plovdiv

Mariana Murdzheva, Stefan Kostianev, Victoria Sarafian-Ozanian, Blagoi Marinov, Dyliana Vicheva
2020 Folia Medica  
The authors are entirely responsible for the content of their abstracts.  ...  Therefore, titanium-based scaffolds must be modified to improve their osteogenic properties.  ...  Synergistic and/or antagonistic interactions between natural compounds are interesting for the discovery of therapeutic regulators of the complement system.  ... 
doi:10.3897/folmed.63.e60105 fatcat:hqcbgipz6rgphpye4ddr5v23fa
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