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Sum of previous inpatient serum creatinine measurements predicts acute kidney injury in rehospitalized patients [article]

Sam Weisenthal, Haofu Liao, Philip Ng, Martin Zand
2017 arXiv   pre-print
Acute Kidney Injury (AKI), the abrupt decline in kidney function due to temporary or permanent injury, is associated with increased mortality, morbidity, length of stay, and hospital cost.  ...  We explore different feature input structures, including variable-length look-backs and a nested formulation for rehospitalized patients with previous sCr measurements.  ...  Introduction Acute Kidney Injury (AKI), the abrupt decline in kidney function due to temporary or permanent injury, is associated with increased mortality, morbidity, length of stay, and hospital cost  ... 
arXiv:1712.01880v1 fatcat:53f6kzs4ejab7m36kwnaghcj4q

Neutrophil Gelatinase-Associated Lipocalin in Kidney Transplantation Is an Early Marker of Graft Dysfunction and Is Associated with One-Year Renal Function

Isabel Fonseca, José Carlos Oliveira, Manuela Almeida, Madalena Cruz, Anabela Malho, La Salete Martins, Leonídio Dias, Sofia Pedroso, Josefina Santos, Luísa Lobato, António Castro Henriques, Denisa Mendonça
2013 Journal of Transplantation  
Day-1 uNGAL levels accurately predicted DGF (AUC-ROC = 0.93), with a performance higher than serum creatinine (AUC-ROC = 0.76), and similar to cystatin C (AUC-ROC = 0.95).  ...  We conducted a prospective study in 40 consecutive KTx recipients to evaluate serial changes of uNGAL within the first week after KTx and assess its performance in predicting DGF (dialysis requirement  ...  The remaining kits were financed by funds of Unit for Multidisciplinary Investigation in Biomedicine, Porto, Portugal. The investigators also thank Dr.  ... 
doi:10.1155/2013/650123 pmid:24288591 pmcid:PMC3833111 fatcat:miriozebvvf4vnege6zteadpue

Oxidative Stress in Kidney Transplantation

Isabel Fonseca, Henrique Reguengo, Manuela Almeida, Leonídio Dias, La Salete Martins, Sofia Pedroso, Josefina Santos, Luísa Lobato, António Castro Henriques, Denisa Mendonça
2014 Transplantation  
At all time points after KTx, mean MDA levels were significantly higher in patients developing DGF (n=18).  ...  Oxidative stress is one of the most important components of the ischemia-reperfusion process after kidney transplantation (KTx) and increases with graft dysfunction. Methods.  ...  ACKNOWLEDGMENTS The authors thank Astellas Pharma Portugal for their valuable contribution in supporting the acquisition of reagents for measuring malondialdehyde and all of the antioxidant parameters.  ... 
doi:10.1097/ pmid:24406454 fatcat:jey3qlk2tngbhdpqqzk777p2hy

Predictors of progression to chronic dialysis in survivors of severe acute kidney injury: a competing risk study

Ziv Harel, Chaim M Bell, Stephanie N Dixon, Eric McArthur, Matthew T James, Amit X Garg, Shai Harel, Samuel Silver, Ron Wald
2014 BMC Nephrology  
Survivors of acute kidney injury are at an increased risk of developing irreversible deterioration in kidney function and in some cases, the need for chronic dialysis.  ...  Results: We identified 4 383 patients with acute kidney injury requiring temporary in-hospital dialysis who survived to discharge.  ...  Acknowledgments This study was funded by a Research Chair in Continuity of Care and Patient Safety from the Canadian Patient Safety Institute and the Canadian Institutes of Health Research.  ... 
doi:10.1186/1471-2369-15-114 pmid:25012724 pmcid:PMC4105112 fatcat:v5guzav4lzfkhfffqr532zieo4

Clinical features of and risk factors for normoalbuminuric diabetic kidney disease in hospitalized patients with type 2 diabetes mellitus: a retrospective cross-sectional study

Qi Dai, Nan Chen, Ling Zeng, Xin-Jie Lin, Feng-Xiu Jiang, Xiong-Jie Zhuang, Ze-Yuan Lu
2021 BMC Endocrine Disorders  
NADKD is more common in patients with normoalbuminuric T2DM with older age, previous use of RASIs, and good glycemic control.  ...  The prevalence of stroke, cardiovascular events, carotid plaque, and peripheral arterial disease in NADKD was significantly higher than in a non-DKD control group (normoalbuminuric T2DM patients with eGFR  ...  We thank Liwen Bianji, Edanz Editing China (, for editing the English text of a draft of this manuscript.  ... 
doi:10.1186/s12902-021-00769-8 pmid:34022855 pmcid:PMC8141213 fatcat:pw24xda3dzfbzc4et2jjshp6ta

Newphrologist: The Intensive Care Kidney Specialist

Jerry Yee
2013 Advances in Chronic Kidney Disease  
Enhanced Poison Elimination in Critical Care  ...  [57] [58] [59] [60] This substance, measured in serum, provides a more precise measurement of GFR than serum creatinine.  ...  Acute kidney injury in patients with acute lung injury: Impact of fluid accumulation on classification of acute kidney injury and associated outcomes.  ... 
doi:10.1053/j.ackd.2012.10.011 pmid:23265589 fatcat:txshbvwyk5dsdpsy6b3jelog2m

Determinants of In‐Hospital Mortality After Percutaneous Coronary Intervention: A Machine Learning Approach

Subhi J. Al'Aref, Gurpreet Singh, Alexander R. van Rosendael, Kranthi K. Kolli, Xiaoyue Ma, Gabriel Maliakal, Mohit Pandey, Bejamin C. Lee, Jing Wang, Zhuoran Xu, Yiye Zhang, James K. Min (+2 others)
2019 Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease  
using the output measure of the area under the curve ( AUC ) and the associated 95% CIs.  ...  The ability to accurately predict the occurrence of in-hospital death after percutaneous coronary intervention is important for clinical decision-making.  ...  For instance, acute kidney injury following PCI has been consistently shown to be associated with the occurrence of both in-hospital and postdischarge adverse cardiovascular events.  ... 
doi:10.1161/jaha.118.011160 pmid:30834806 pmcid:PMC6474922 fatcat:c22fts452bfm7js3khaklqj55a

Novel Patient‐Centered Approach to Facilitate Same‐Day Discharge in Patients Undergoing Elective Percutaneous Coronary Intervention

Amit P. Amin, Patricia Crimmins‐Reda, Samantha Miller, Brandon Rahn, Mary Caruso, Andrew Pierce, Brandy Dennis, Marissa Pendegraft, Katrine Sorensen, Howard I. Kurz, John M. Lasala, Alan Zajarias (+3 others)
2018 Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease  
Methods and Results--Our objectives were as follows: (1) to evaluate time trends in SDD; (2) to compare (a) mortality, bleeding, and acute kidney injury, (b) patient satisfaction, and (c) hospital costs  ...  Although SDD patients were comparable to NSDD patients, SDD was not associated with adverse outcomes (0% mortality, 0% bleeds, and 0.4% acute kidney injury). Patient satisfaction was high with SDD.  ...  level <16 g/dL, and preprocedure hemoglobin level not missing. † Acute kidney injury was defined according to the Acute Kidney Injury Network criteria as the change from preprocedure to peak serum creatinine  ... 
doi:10.1161/jaha.117.005733 pmid:29449273 pmcid:PMC5850176 fatcat:ppeleo76ljeb3oh6dqam23ybiu

Diagnosis and management of acute heart failure

Dilek Ural, Yuksel Cavusoglu, Mehmet Eren, Kurtulus Karauzum, Ahmet Temizhan, Mehmet Birhan Yilmaz, Mehdi Zoghi, Kumudha Ramassubu, Biykem Bozkurt
2015 Anatolian Journal of Cardiology  
Acute heart failure (AHF) is a life threatening clinical syndrome with a progressively increasing incidence in general population.  ...  This consensus report summarizes clinical and prognostic classification of AHF, its worldwide and national epidemiology, diagnostic work-up, principles of approach in emergency department, intensive care  ...  Conflict of interest: None declared.  ... 
doi:10.5152/anatoljcardiol.2015.6567 pmid:26574757 pmcid:PMC5336936 fatcat:6xxafeuj4nbs7ldocdetahuipq

40th International Symposium on Intensive Care & Emergency Medicine

2020 Critical Care  
There was increased distribution of Aβ1-40 in regions of acute vascular disruption, resulting in lower BBB permeability.  ...  increased distribution of Aβ1-40 in a "banding" pattern within a region of acute vascular disruption.  ...  Acknowledgements We thank the Department of Education of the Basque Government (PIBA 2019-57) and the University of the Basque Country UPV/EHU (PPG17/65, GIU 17/32) for their financial support.  ... 
doi:10.1186/s13054-020-2772-3 pmid:32209112 fatcat:mvoe5mw7cvbrhjs7qmcdirb7ke

Original Research Abstract

2019 European Heart Journal, Supplement  
of delay in seeking medical care can increase the relative risk of 1-year mortality as 7.5% in patients with acute myocardial infarction.  ...  patients were presented with acute coronary syndrome out of which 53.5% (1714) were ST elevation myocardial infraction.  ...  Some evidence exists about the possible relationship between BUN and creatinine serum in peripheral blood vessel as a sign of acute renal injury (azotemia) with this disease severity.  ... 
doi:10.1093/eurheartj/suz182 fatcat:uctw342v2bd6tjymfdjqmzujiq

Poster Session 2

2014 European Journal of Heart Failure  
While it is important to detect renal injury in the early phase in CRS type1, acute kidney injury (AKI) based on AKIN criteria is defined by serum creatinine or urinary output.  ...  P767 Acute coronary syndrome and acute kidney injury -relevant?  ...  Objects: To evaluate the clinical characteristics and therapeutic measures of patients in a cohort of heart failure in our center.  ... 
doi:10.1002/ejhf.93_13 fatcat:myow3rno6ndohhvn3plqhhafse

Myocardial Ischemia and Infarction

2009 Journal of the American College of Cardiology  
Conclusions: Elevated preoperative levels of serum sCD40L, a measure of platelet activation, predicts the development of AF post-CABG.  ...  in serum albumin levels during hospitalization in patients with acute myocardial infarction (AMI).  ...  A day before, PWV was measured noninvasively by Complior in all patients.  ... 
doi:10.1016/j.jacc.2009.01.018 fatcat:qpfjfiwy5ng3dn6wqck3gkf2ea

Abstracts from the AGS and AFAR 1986 Annual Meeting, Chicago November 16 to 19

1986 Journal of The American Geriatrics Society  
It was also related to CT measures of muscle mass and kidney size (p<.10).  ...  Serum creatinine levels in our patients were normal or slightly elevated (mean: 1.18 + 0.38, range: 0.6 - 1.9 mg/dl) yet estimated creatinine clearances were distinctly reduced (mean: 44.1 + 11.7 ml/min  ... 
doi:10.1111/j.1532-5415.1986.tb07274.x fatcat:hlf7ejczmrd6zi67aazbcvnvla

2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines

C. W. Yancy, M. Jessup, B. Bozkurt, J. Butler, D. E. Casey, M. H. Drazner, G. C. Fonarow, S. A. Geraci, T. Horwich, J. L. Januzzi, M. R. Johnson, E. K. Kasper (+12 others)
2013 Circulation  
The risk of hyperkalemia increases progressively when serum creatinine is >1.6 mg/dL.* In elderly patients or others with low muscle mass in whom serum creatinine does not accurately reflect glomerular  ...  Measurement of other clinically available tests such as biomarkers of myocardial injury or fibrosis may be considered for additive risk stratification in patients with acutely decompensated HF. 248,253,256,257,261  ... 
doi:10.1161/cir.0b013e31829e8776 pmid:23741058 fatcat:mzwuppxw2revldhypknruen5zi
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