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Classification of 8-dimensional rank two commutative semifields [article]

Michel Lavrauw, Morgan Rodgers
2016 arXiv   pre-print
We classify the rank two commutative semifields which are 8-dimensional over their center F_q. This is done using computational methods utilizing the connection to linear sets in PG(2,q^4).  ...  The implications of these results are detailed for other geometric structures such as semifield flocks, ovoids of parabolic quadrics, and eggs.  ...  F q -linear set in C PG(2, q n ) contains a dual F q -subline on an internal point w.r.t.  ... 
arXiv:1606.06151v2 fatcat:pdlefywj25cg5lxnnpc3metlbe

On minimum size blocking sets of the outer tangents to a hyperbolic quadric in PG(3,q)

Bart De Bruyn, Binod Kumar Sahoo
2019 Finite Fields and Their Applications  
Let Q + (3, q) be a hyperbolic quadric in PG(3, q) and T 1 be the set of all lines of PG(3, q) meeting Q + (3, q) in singletons (the so-called outer tangents).  ...  If k is the minimum size of a T 1 -blocking set in PG(3, q), then we prove that k ≥ q 2 − 1.  ...  Sciences in March-April 2017.  ... 
doi:10.1016/j.ffa.2018.11.002 fatcat:nszabsrc4rgwhddfe53tm65tua

Low dimensional models of the finite split Cayley hexagon [article]

John Bamberg, Nicola Durante
2012 arXiv   pre-print
We provide a model of the split Cayley hexagon arising from the Hermitian surface H(3,q^2), thereby yielding a geometric construction of the Dickson group G_2(q) starting with the unitary group SU_3(q)  ...  the support of a GNSAGA-grant.  ...  The first author acknowledges the support of a Marie Curie Incoming International Fellowship within the 6th European Community Framework Programme (MIIF1-CT-2006-040360), and the second author acknowledges  ... 
arXiv:1201.4523v1 fatcat:l36fa2gtnve6xksndornhuxff4

Finite geometries

A. Blokhuis, J. W. P. Hirschfeld, D. Jungnickel, J. A. Thas
2008 Designs, Codes and Cryptography  
Schmidt, Asymptotic nonexistence of dihedral difference sets L. Storme, On multiple blocking sets in Galois planes P. Sziklai, Small multiple blocking sets in PG(4, q 2 ) with respect to planes K.  ...  Edel, Extensions of generalized product caps A. Gács, Some new results about directions D.G. Glynn, The invariant graphs, tournaments and codes of projective planes of even order P.  ...  In the second part of the talk we show that a partial spread of size k in P G(2, q) is equivalent to a set of k − 1 points in AG(2, q 2 ) not determining a Baer subline.  ... 
doi:10.1007/s10623-007-9162-6 fatcat:yd5cqfmlrfa7zlzeifhhx7qfg4

Orthotopic patient-derived xenografts of paediatric solid tumours

Elizabeth Stewart, Sara M. Federico, Xiang Chen, Anang A. Shelat, Cori Bradley, Brittney Gordon, Asa Karlstrom, Nathaniel R. Twarog, Michael R. Clay, Armita Bahrami, Burgess B. Freeman, Beisi Xu (+13 others)
2017 Nature  
E.S. was supported by the St. Baldrick's Foundation and the National Pediatric Cancer Foundation (NPCF).  ...  Acknowledgments We thank Angela McArthur for editing the manuscript.  ...  96%) in methanol as an internal standard.  ... 
doi:10.1038/nature23647 pmid:28854174 pmcid:PMC5659286 fatcat:i3ni72ksf5bidodjqmhjt6ojqy

Tight sets and m-ovoids of generalised quadrangles

John Bamberg, Maska Law, Tim Penttila
2009 Combinatorica  
A characterization of the sets of internal and external points of a conic Frank De Clerck, joint work with Nikias De Feyter We provide a characterization of the sets of internal and external points of  ...  An ovoid of Q + (2n + 1, q) is a set O of points of Q + (2n + 1, q) such that every generator meets O in exactly one point; it contains q n + 1 points.  ... 
doi:10.1007/s00493-009-2179-x fatcat:3lv4kl6qafbfdemivsj73n6miq

Hyperovals on H(3,q2)

Antonio Cossidente
2011 Journal of combinatorial theory. Series A  
A construction of an irreducible 2-ovoid of H(3, 25) and some results on packings of the Hermitian curve are given.  ...  Infinite families of hyperovals of the generalized quadrangle H(3, q 2 ) are constructed. Some sporadic examples are also presented.  ...  Replace these points with those in the intersection of H(3, q 2 ) with the polar line of . The resulting set contains no conjugate pairs of points and has the same size as O. Hence it is an ovoid.  ... 
doi:10.1016/j.jcta.2010.11.016 fatcat:r6kcr7k5yzc6bmeccgjaup4tn4

Multiple recent sex chromosome fusions in Drosophila virilis associated with elevated satellite DNA abundance [article]

Jullien M Flynn, Kevin B Hu, Andrew G. Clark
2021 bioRxiv   pre-print
We find that the centromere-to-centromere fusions resulted in up to a 21% nondisjunction rate between the X and Y chromosomes in males, adding a fitness cost.  ...  This was further supported by a significant decrease in DNA breakage in an otherwise genetically identical substrain that lost the chromosome fusion and several megabases of satellite DNA.  ...  We next set up a two-464 generation crossing scheme ( Figure 1A) .  ... 
doi:10.1101/2021.06.14.448339 fatcat:ctyy4ciqune6liejspthed5ee4

Macrophages employ quorum licensing to regulate collective activation

Joseph J. Muldoon, Yishan Chuang, Neda Bagheri, Joshua N. Leonard
2020 Nature Communications  
The results show that bimodal phenotypic partitioning of macrophages is primed during the resting state, dependent on cumulative history of cell density, predicted by extrinsic noise in transcription factor  ...  expression, and independent of canonical LPS-induced intercellular feedback in the tumor necrosis factor (TNF) response.  ...  secretion assay; Sean Allen for reagents; and Sarah Stainbrook, Gokay Yamankurt, and members of the Leonard lab and Bagheri lab for discussions.  ... 
doi:10.1038/s41467-020-14547-y pmid:32054845 pmcid:PMC7018708 fatcat:4wtvdr6eavgxvkvxcgutw576su

Monads for Instantons and Bows [article]

Sergey A. Cherkis, Jacques Hurtubise
2019 arXiv   pre-print
Instantons on the Taub-NUT space are related to 'bow solutions' via a generalization of the ADHM-Nahm transform.  ...  For both the instanton and the bow solution we produce two monads encoding each of them respectively.  ...  The authors also thank the Banff International Research Station for hospitality during the workshop The Analysis of Gauge-Theoretic Moduli Spaces where this work was completed.  ... 
arXiv:1709.00145v2 fatcat:szzkhnnv4rhsvmwtdifdfzm7vm

Resistance to receptor-blocking therapies primes tumors as targets for HER3-homing nanobiologics

Jessica D. Sims, Jan Michael Taguiam, Felix Alonso-Valenteen, Janet Markman, Hasmik Agadjanian, David Chu, Jay Lubow, Ravinder Abrol, Dustin Srinivas, Anjali Jain, Bingchen Han, Ying Qu (+11 others)
2018 Journal of Controlled Release  
A growing number of such tumors are characterized by prominent expression of the human epidermal growth factor receptor 3 (HER3) on the cell surface.  ...  These have improved therapeutic efficacy and safety compared to traditional treatment modalities but resistance arises in the majority of clinical cases.  ...  The minced tissue and media were incubated for 16 h in a table-top shaker at 37°C and 210 RPM. Media/cell mixture was spun down in a 50 mL conical tube at 80 ×g for 30 s in a clinical centrifuge.  ... 
doi:10.1016/j.jconrel.2017.12.024 pmid:29288681 pmcid:PMC5807213 fatcat:ldxe7enddbbtdoeu7hshtirlzu

Anti-CD40 Antibodies Fused to CD40 Ligand Have Superagonist Properties

Valentina Ceglia, Sandra Zurawski, Monica Montes, Aurélie Bouteau, Zhiqing Wang, Jerome Ellis, Botond Z. Igyártó, Yves Lévy, Gerard Zurawski
2021 Journal of Immunology  
The increased anti-CD40-CD40L Ab potency was independent of higher order aggregation.  ...  The tetravalent configuration of anti-CD40-CD40L Abs promotes CD40 cell surface clustering and internalization and is the likely mechanism of increased receptor activation.  ...  Acknowledgments We thank Yong-Jun Liu, the previous Baylor Institute for Immunology Research Director, for initiating the development of anti-CD40 Abs with enhanced agonist potency.  ... 
doi:10.4049/jimmunol.2000704 pmid:34551965 pmcid:PMC8490940 fatcat:layrezoxurcjrbi46iwswq3k2i

On sets with few intersection numbers in finite projective and affine spaces

Nicola Durante
2014 unpublished
In this paper we study sets X of points of both affine and projective spaces over the Galois field GF(q) such that every line of the geometry that is neither contained in X nor disjoint from X meets the  ...  set X in a constant number of points and we determine all such sets.  ...  Acknowledgements The author thanks Tim Penttila and Cheryl Praeger for the helpful discussions on group theory.  ... 
fatcat:v2vi63cpzjbhjcsqkji36mj6ya

Birth Control and Catholic Doctrine

Alan Rhodes
1960 Science  
In order to describe the measured dis- tributions found by Miller and Reite- meier, a mathematical model was set up.  ...  Achievements in outer-space activities are, of course, the prime example of this. Perhaps a few comments about our space and mis- sile program in this light are in order.  ... 
doi:10.1126/science.131.3406.1010-c fatcat:6n4r7u34ynb6vapu6vjrjvbb6m

Birth Control and Catholic Doctrine

Alan Rhodes
1960 Science  
In order to describe the measured dis- tributions found by Miller and Reite- meier, a mathematical model was set up.  ...  Achievements in outer-space activities are, of course, the prime example of this. Perhaps a few comments about our space and mis- sile program in this light are in order.  ... 
doi:10.1126/science.131.3406.1010.c fatcat:qqn2knqq2rcshmv6576fi3gbga
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