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Microscopic Optical Projection Tomography In Vivo

Matthias Rieckher, Udo Jochen Birk, Heiko Meyer, Jorge Ripoll, Nektarios Tavernarakis, Jörg Langowski
2011 PLoS ONE  
This system offers considerable advantages over currently available methods when imaging dynamic developmental processes and animal ageing; it permits monitoring of spatio-temporal gene expression and  ...  We describe a versatile optical projection tomography system for rapid three-dimensional imaging of microscopic specimens in vivo.  ...  Some nematode strains used in this work were provided by the Caenorhabditis Genetics Center, which is funded by the NIH National Center for Research Resources (NCRR).  ... 
doi:10.1371/journal.pone.0018963 pmid:21559481 pmcid:PMC3084718 fatcat:7f4sp7slw5bebicjz4xxctypuq

Scanning Probe Microscope-Based Fluid Dispensing

Murali Ghatkesar, Hector Garza, Friedjof Heuck, Urs Staufer
2014 Micromachines  
Scanning probe microscope (SPM) is one such device that has evolved from atomic force microscope for imaging to a variety of microscopes by integrating different physical and chemical mechanisms.  ...  Therefore, integration of various technologies with numerous functionalities in one single device is important.  ...  However, to image droplet diameters of 1 micron or less, scanning electron microscope or various modes of atomic force microscope are used.  ... 
doi:10.3390/mi5040954 fatcat:763oufy7r5bgfb3yuzwef6ztkm

Modeling Microscopic Chemical Sensors in Capillaries [article]

Tad Hogg
2008 arXiv   pre-print
This paper models microscopic robots and red blood cells (erythrocytes) in capillaries using realistic distorted cell shapes.  ...  Nanotechnology-based microscopic robots could provide accurate in vivo measurement of chemicals in the bloodstream for detailed biological research and as an aid to medical treatment.  ...  Thus the simpler model is sufficient for design studies of microscopic chemical sensors operating within capillaries.  ... 
arXiv:0811.1520v1 fatcat:vicohnufkrgotgdkjo3glncpti

Cryo-EM: beyond the microscope

Lesley A Earl, Veronica Falconieri, Jacqueline LS Milne, Sriram Subramaniam
2017 Current Opinion in Structural Biology  
We highlight advances in image processing that permit high resolution structure determination even in the presence of structural and conformational heterogeneity.  ...  Initial successes in obtaining near-atomic resolution structures with cryo-EM were enabled to a large extent by advances in microscope and detector technology.  ...  Alberto Bartesaghi and Erin Tran for helpful comments on the manuscript, and Dr. Soojay Banerjee for helpful discussions.  ... 
doi:10.1016/ pmid:28646653 pmcid:PMC5683925 fatcat:37uxufuacffbhhhzvp6xzn7bqe

Modeling Microscopic Chemical Sensors in Capillaries

Tad Hogg
2009 The Open Nanomedicine Journal  
This paper models microscopic robots and red blood cells (erythrocytes) in capillaries using realistic distorted cell shapes.  ...  The models evaluate two sensing scenarios: robots moving with the cells past a chemical source on the vessel wall, and robots attached to the wall for longer-term chemical monitoring of chemicals released  ...  Thus the simpler model is sufficient for design studies of microscopic chemical sensors operating within capillaries.  ... 
doi:10.2174/1875933500902010001 fatcat:frb2zcxe3fhljgbdjdqd6xzo3i

Kinetic limits for sensing tip morphology in near‐field scanning optical microscopes

B. I. Yakobson, P. J. Moyer, M. A. Paesler
1993 Journal of Applied Physics  
In the following study, we concentrate on one particular type of such instrument, the near-field scanning optical microscope, or NSOM.  ...  The lateral spatial resolution provided by near-field scanning optical microscopes depends critically on the shape and size of the sharpened tip of the optical fiber used as a source of light or sensing  ...  In the following study, we concentrate on one particular type of such instrument, the near-field scanning optical microscope, or NSOM.  ... 
doi:10.1063/1.353911 fatcat:yr3xaox33ra5zid6ml3eitjmxe

A Miniature Head-Mounted Two-Photon Microscope

Fritjof Helmchen, Michale S. Fee, David W. Tank, Winfried Denk
2001 Neuron  
and Harris, single-cell activity, which depends on synaptic back-1995; Sabharwal et al., 1999), but none of them has been applied to in vivo imaging of neurons.  ...  have been using vibrations of the fiber tip.  ...  Based on the diameter of capillaries (about 5-6 m), we estimate the field of view to be ‫56ف‬ m on side.  ... 
doi:10.1016/s0896-6273(01)00421-4 pmid:11580892 fatcat:y4jaffnerrcxzorlr3xjyft7f4

A microscopic view on the renal endothelial glycocalyx

Martijn J. C. Dane, Bernard M. van den Berg, Dae Hyun Lee, Margien G. S. Boels, Gesa L. Tiemeier, M. Cristina Avramut, Anton Jan van Zonneveld, Johan van der Vlag, Hans Vink, Ton J. Rabelink
2015 AJP - Renal Physiology  
A microscopic view on the renal endothelial glycocalyx.  ...  Although all these techniques have shown the presence of glycocalyx components on the endothelial cells, a considerable part of these studies are done using epifluorescence microscopy, which has major  ...  Although the same principle is used to study the role of heparan sulfates present on glomerular endothelial cells (89) , it has never been used to image these heparan sulfates specifically on the luminal  ... 
doi:10.1152/ajprenal.00532.2014 pmid:25673809 fatcat:52l5nlpzojg5th4bzigkpdle6e

Recording Three Leeuwenhoek Microscopes

Brian Ford
2015 infocus Magazine  
microscope substantiates) of considerable value.  ...  From the initial images, almost 70 entire frames or portions thereof were selected to compile a composite view of the entire microscope.  ... 
doi:10.22443/rms.inf.1.129 fatcat:xnt7ed6qija5zjctnhllu7gtze

Capillary wetting of profiled polyester fibres-a comparison between macroscopic and microscopic analysis

G Glavan, M Kurečič, U Maver, K Stana-Kleinschek, I Drevenšek-Olenik
2018 Materials Research Express  
method for investigation of the wetting process in single fibres is reported.  ...  A comparative study between the standard Washburn macroscale method for determination of the capillary wetting rate in a nonwoven textile fibre mesh and the polarization optical video-microscopybased microscale  ...  Acknowledgements The authors acknowledge financial support of the Slovenian research program P1-092 ("Light and Matter") and P2-0118 ("Textile Chemistry"), as well as national research project L2-5492.  ... 
doi:10.1088/2053-1591/aaa4ec fatcat:m6dcqcqcijfoxoz7i4f2x4n7ua

Morquio syndrome: electron microscopic findings

T Leslie
2005 British Journal of Ophthalmology  
LETTERS Br J Ophthalmol 2005;89:917-929 917 on 22 July 2018 by guest. Protected by copyright.  ...  (C) MRI of the orbits was significant for an intraocular tumour that displayed high signal intensity on T1 weighted images. On T2 weighted images it displayed low signal intensity.  ...  We believe this factor, and its own diurnal variation, should be taken into consideration in future studies.  ... 
doi:10.1136/bjo.2004.055400 pmid:15965185 pmcid:PMC1772727 fatcat:m5tfagjy5ne3fads5ca2ut52ae

A compact combined ultrahigh vacuum scanning tunnelling microscope (UHV STM) and near-field optical microscope

R A J Woolley, J A Hayton, S Cavill, Jin Ma, P H Beton, P Moriarty
2008 Measurement science and technology  
We show that controlled contact with metal surfaces considerably enhances the STM imaging capabilities of fibre-optic tips.  ...  Indium tin oxide (ITO)-coated fibre-optic tips capable of high quality STM imaging and tunnelling spectroscopy are fabricated using a simple and reliable method which foregoes the electroless plating strategy  ...  the Engineering and Physical Sciences Research Council (EPSRC) under grant GR-R34608-1, the EU Framework Programme 6 Marie Curie scheme (under grant MEST-CT-2004-506854 (NANOCAGE)) and the University of  ... 
doi:10.1088/0957-0233/19/4/045301 fatcat:bsr5vvalgfhq7fu2ona2g3wxne

Microscopic investigation of the hydro-mechanical behavior of unsaturated granular media with X-ray CT

Marius Milatz, Jurgen Grabe
2019 Japanese Geotechnical Society Special Publication  
With a sufficient resolution (voxel size) and a sequence of images over time, CT-images also allow to visualize processes in unsaturated soils, where microscopic features, such as the phase distribution  ...  The distribution of pore water, the change in interfacial area as well as the shape of capillary bridges can be analyzed with focus on the loss of capillary cohesion within the specimen on its way to collapse  ...  In the hydraulic studies, mainly the water retention behavior and its microscopic representation by multiphase flow processes, is of interest (e. g.  ... 
doi:10.3208/jgssp.v07.095 fatcat:xlicp2icorg5zfryp46j34j7ra

Self-assembly of microscopic tablets within polymeric thin films: a possible pathway towards new hybrid materials

Seyed Mohammad Mirkhalaf Valashani, Christopher J. Barrett, Francois Barthelat
2015 RSC Advances  
Self-assembly of highly regular micron-sized platelets opens new pathways for the development of novel biomimetic materials, protective coatings, flexible electronics, and tunable optical devices.  ...  The authors would also like to acknowledge Professor Sylvain Coulombe for lending his scanning electron microscope, and Jorge Lehr and Larissa Jorge for assisting with the imaging, and Béatrice Lego for  ...  Acknowledgements This work was supported by the Fonds de Recherche du Québec -Nature et technologies and by the Natural Sciences and Engineering Research Council of Canada.  ... 
doi:10.1039/c4ra15166f fatcat:xodu7zgxjzecfghgmxxbwtz2ce

Ultrasonic assisted nanomanipulations with atomic force microscope

P.M. Lytvyn, V. Lashkaryov Institute of Semiconductor Physics, NAS of Ukraine, 41, prospect Nauky, 03028 Kyiv, Ukraine, e-mail:
2009 Semiconductor Physics, Quantum Electronics & Optoelectronics  
Demonstrated experimentally in this work was the possibility of controlled handling the nanoparticles with the size from 50 up to 250 nm on a semiconductor surface by using an atomic force microscope under  ...  Also in this study, possible mechanisms in which ultrasound may influence the particle-surface interaction and the probe-particle (surface) interaction have been analyzed.  ...  This effect can be employed in the course of manufacturing the model samples of nanostructures to ensure separation and positioning the nanoparticles.  ... 
doi:10.15407/spqeo13.01.036 fatcat:7dkks6wc4rbwvlhchccisshmqe
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