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Simultaneous Model Selection and Estimation for Mean and Association Structures with Clustered Binary Data [article]

Xin Gao, Grace Y. Yi
2012 arXiv   pre-print
HPGEE2 with a smoothly clipped absolute deviation (SCAD) penalty is shown to have the oracle property for the mean and association models.  ...  This paper investigates the property of the penalized estimating equations when both the mean and association structures are modelled.  ...  When both the mean and association structures are modeled, we may be interested in model selection for mean model only, or for association model only, or for both mean and association models together.  ... 
arXiv:1208.4379v1 fatcat:qlbuiwsodbgbpfrgc5cazvt2mi

Heterogeneous autoregressive model with structural break using nearest neighbor truncation volatility estimators for DAX

Wen Cheong Chin, Min Cherng Lee, Grace Lee Ching Yap
2016 SpringerPlus  
evaluations as compared with the standard HAR models.  ...  In this study, we propose a structural break heavy-tailed heterogeneous autoregressive (HAR) volatility econometric model with the enhancement of jump-robust estimators.  ...  For the second remedy, one may use the econometric models that directly deal with structural breaks.  ... 
doi:10.1186/s40064-016-3465-x pmid:27872795 pmcid:PMC5097780 fatcat:etrfoi4ll5fyzepib62bkdxnzi

Comparative Perturbation-Based Modeling of the SARS-CoV-2 Spike Protein Binding with Host Receptor and Neutralizing Antibodies : Structurally Adaptable Allosteric Communication Hotspots Define Spike Sites Targeted by Global Circulating Mutations [article]

Gennady M. Verkhivker, Steve Agajanian, Deniz Yazar Oztas, Grace Gupta
2021 bioRxiv   pre-print
preferentially select structurally plastic and energetically adaptable allosteric centers to differentially modulate collective motions and allosteric interactions in the complexes with the ACE2 enzyme  ...  Using alanine scanning and mutational sensitivity analysis, we have shown that K417, E484 and N501 residues correspond to key interacting centers with a significant degree of structural and energetic plasticity  ...  In this study, CG-CABS model [100] [101] [102] [103] [104] was used for simulations of the crystal structures of the SARS-CoV-2 RBD complex with ACE2 (pdb id 6M0J) 15 and complexes formed by the dissociated  ... 
doi:10.1101/2021.02.21.432165 fatcat:vil5bq54vnbqhaiifxoa3cpku4

Verification of tree-based hierarchical read-copy update in the Linux kernel

Lihao Liang, Paul E. McKenney, Daniel Kroening, Tom Melham
2018 2018 Design, Automation & Test in Europe Conference & Exhibition (DATE)  
Read-Copy Update (RCU) is a scalable, high-performance Linux-kernel synchronization mechanism that runs low-overhead readers concurrently with updaters.  ...  We then discuss how to construct a model directly from Tree RCU's source code in C, and use the CBMC model checker to verify its safety and liveness properties.  ...  As with the rcu state structure, different flavors of RCU maintain their own per-CPU rcu data structures.  ... 
doi:10.23919/date.2018.8341980 dblp:conf/date/LiangMKM18 fatcat:72lvsnmucjdf7jzlvfwp4ckuhu

Variable Selection via Grace-AKO with Applications in Genomics [article]

Peixin Tian, Yiqian Hu, Zhonghua Liu, Yan Dora Zhang
2022 bioRxiv   pre-print
Simulation studies show that Grace-AKO has better performance in FDR control in finite sample settings than the original Grace model.  ...  Grace-AKO finally identifies 47 candidate genes associated with PSA level, and more than 75% of the detected genes can be validated.  ...  Grace model with a pre-specified mFDR level at 0.1. p n = 100 n = 200 n = 300 Grace-AKO Grace Grace-AKO Grace Grace-AKO Grace 10 0.01 (0.018) 0.15 (0.032) 0.03 (0.032) 0.22 (0.049) 0.03 (0.025) 0.26 (0.053  ... 
doi:10.1101/2022.03.30.486361 fatcat:zlxrvvgxunfb5e7c3hmsvo6aaa

Optimal CD4 Count for Initiating HIV Treatment

Fiona M. Ewings, Deborah Ford, A. Sarah Walker, James Carpenter, Andrew Copas
2014 Epidemiology  
Other approaches such as the g-formula or g-estimation of structural nested models could be used as alternatives to dynamic marginal structural models. g-estimation of structural nested models has the  ...  potential to be more efficient than dynamic marginal structural models and has fewer parametric assumptions than the g-formula. 21 However, structural nested models are less robust to model misspecification  ... 
doi:10.1097/ede.0000000000000043 pmid:24487204 pmcid:PMC3914951 fatcat:4qt5nn5lpjci3fq2ke3svxtf3i

Postseismic gravity change after the 2006-2007 great earthquake doublet and constraints on the asthenosphere structure in the central Kuril Islands

Shin-Chan Han, Jeanne Sauber, Fred Pollitz
2016 Geophysical Research Letters  
The GRACE data are best fit with a model of 25-35 km for the elastic thickness and ~10 18 Pa s for the Maxwell viscosity of the asthenosphere.  ...  The 2006 M w 8.3 thrust and 2007 M w 8.1 normal fault earthquakes of the central Kuril Islands resulted in significant postseismic gravity change in GRACE but without a discernible coseismic gravity change  ...  The GRACE data for this paper are available at and We thank Jeanne Hardebeck and Ruth Harris for their comments on a preliminary draft.  ... 
doi:10.1002/2016gl068167 pmid:27642200 pmcid:PMC5023021 fatcat:fwxqwx4bxzgy5nw5ewqg7albpe

Effects of the Tibetan Plateau Crustal Structure on the Inversion of Water Trend Rates Using Simulated GRACE/GPS Data

Hansheng Wang, Longwei Xiang, Patrick Wu, Holger Steffen, Lulu Jia, Liming Jiang, Qiang Shen
2013 Terrestrial, Atmospheric and Oceanic Sciences  
However, when using simulated GPS data, effects of crustal differences are very prominent suggesting that an Earth model with a realistic crustal structure instead of PREM should be used for this case.  ...  The crustal structure under the Tibetan Plateau is quite different from that given by the commonly used Preliminary Reference Earth Model (PREM, Dziewonski and Anderson 1981).  ...  In this case a modified Earth model with a more realistic crustal structure such as MQ-PREM in this paper should be used.  ... 
doi:10.3319/tao.2012.09.21.01(tibxs) fatcat:4sjxub4qbnc4rgorsmi7r3gtie

Inference of mantle viscosity from GRACE and relative sea level data

Archie Paulson, Shijie Zhong, John Wahr
2007 Geophysical Journal International  
We calculate a large number of forward models for PGR with different viscosity structures.  ...  Model misfits to the GRACE data are computed as described above for the RSL data (eq. 1): with χ 2 GRACE = 1 M M j=1 g data j − g model j σ j 2 , (2) where σ j is the error in the GRACE gravity trend at  ... 
doi:10.1111/j.1365-246x.2007.03556.x fatcat:rdvdd7jeevbjdfd4tybjla47ja

Stateless model checking of the Linux kernel's read–copy update (RCU)

Michalis Kokologiannakis, Konstantinos Sagonas
2019 International Journal on Software Tools for Technology Transfer (STTT)  
More importantly, we were able to verify both the publish-subscribe and the grace-period guarantee, with the latter being the basic and most important guarantee that RCU offers, on several Linux kernel  ...  RCU's implementation is quite involved, as RCU interacts with many other subsystems of the Linux kernel, making the precise modeling of RCU's environment arduous.  ...  Compliance with ethical standards Data availability The Nidhugg tool is available at https://www.github. com/nidhugg/nidhugg.  ... 
doi:10.1007/s10009-019-00514-6 fatcat:p5ifzuyua5ew7dhxdx2aq2zctq

Species richness and soil properties in Pinus ponderosa forests: A structural equation modeling analysis

Daniel C. Laughlin, Scott R. Abella, W. Wallace Covington, James B. Grace
2007 Journal of Vegetation Science  
We evaluated multivariate models of plant species richness using structural equation modeling.  ...  Richness was strongly related to soil nitrogen in the model, with evidence for both a direct negative effect and an indirect non-linear relationship mediated through understory plant cover.  ...  These multivariate relations were also detected in structural equation model results from coastal wetlands (Gough & Grace 1999) .  ... 
doi:10.1658/1100-9233(2007)18[231:sraspi];2 fatcat:ozloma3u5rd6bcxj7ssbsc5cw4

Postglacial rebound and Earth's viscosity structure from GRACE

Isabella Velicogna, John Wahr
2002 Journal of Geophysical Research  
We thank Mike Watkins and Brooks Thomas for providing their estimates of the GRACE gravity field errors; Dick Peltier for providing the ICE-4 ice model; Mery Molenaar and Frank Bryan for their estimates  ...  . [28] We consider radially symmetric viscosity structures with uniform viscosities in the lower mantle, the transition zone, and the upper mantle.  ...  All secular signals are included along with GRACE measurement errors in the simulated GRACE estimate of PGR.  ... 
doi:10.1029/2001jb001735 fatcat:wnalrdxly5dbzn3rttiftbzifu

Spatio-Temporal Evaluation of Water Storage Trends from Hydrological Models over Australia Using GRACE Mascon Solutions

Xinchun Yang, Siyuan Tian, Wei Feng, Jiangjun Ran, Wei You, Zhongshan Jiang, Xiaoying Gong
2020 Remote Sensing  
In comparison, CLM-4.5 model yielded the best agreement with GRACE but overstated the GRACE-derived TWSA trends due to the overestimation of GWSA.  ...  in TWSA trends between GRACE and hydrological models.  ...  Furthermore, although CLM-4.5 model demonstrated the closest agreement with GRACE, this model overestimates the GRACE-derived rising TWSA trend, with a rate of 3.79 ± 0.52 mm/year.  ... 
doi:10.3390/rs12213578 fatcat:yzkasfv4mzcmjaz655swtldh34

Graph Clustering with Dynamic Embedding [article]

Carl Yang, Mengxiong Liu, Zongyi Wang, Liyuan Liu, Jiawei Han
2017 arXiv   pre-print
To provide more insight, we theoretically analyze our interpretation of network clusters and find its underlying connections with two widely applied approaches for network modeling.  ...  Recent literature on this topic has reached a consensus that node contents and link structures should be integrated for reliable graph clustering, especially in an unsupervised setting.  ...  Describing network clusters with stable in uence propagation, we integrate the leverage of link structures into GRACE by substituting the deep embedding X with the dynamic embeddingX before clustering  ... 
arXiv:1712.08249v1 fatcat:wkll4bj4xrfsxew2dys3jefowu

Performance of Different Ensemble Kalman Filter Structures to Assimilate GRACE Terrestrial Water Storage Estimates Into a High‐Resolution Hydrological Model: A Synthetic Study

Ashkan Shokri, Jeffrey P. Walker, Albert I. J. M. Dijk, Valentijn R. N. Pauwels
2018 Water Resources Research  
Ensemble Kalman filters (EnKFs) are useful tools to combine observations with models to reduce prediction errors.  ...  It was found that all available structures led to an improvement in model performance when measured against a synthetic reference.  ...  the GRACE TWS into the land surface models.  ... 
doi:10.1029/2018wr022785 fatcat:62ghh2gbwjchtlr2zutgs4b4jy
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