Filters








35 Hits in 11.7 sec

Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis [article]

He-ming Huang, Shi-jie Fan, Xiao-ru Zhou, Yan-jun Liu, Xiao Li, Li-ping Liao, Jing Huang, Cui-cui Shi, Liang Yu, Rong Fu, Jian-gao Fan, Yuan-yuan Zhang (+2 others)
<span title="2020-06-11">2020</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
We identified HDAC inhibitor givinostat as a potent inhibitor of macrophages inflammatory activation, and aimed to evaluate the therapeutic potential of givinostat for treatment of NASH.  ...  In conclusion, givinostat appears to be efficacious in reversing diet-induced NASH, and may serve as a therapeutic agent for treatment of human NASH.  ...  Lipid-lowering agents like Stearoyl-CoA Desaturase (SCD1) inhibitors (42) or Thyroid Hormone Receptor agonists (43) are aimed at modulating metabolism and lipid steatohepatitis.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/2020.06.09.141655">doi:10.1101/2020.06.09.141655</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/fajjct4hrbc4pjojw5pxtc7kem">fatcat:fajjct4hrbc4pjojw5pxtc7kem</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20201107035328/https://www.biorxiv.org/content/biorxiv/early/2020/06/11/2020.06.09.141655.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/8a/f7/8af78d0b66e981621716a32f6d152e7aae11e357.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/2020.06.09.141655"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

l-Ascorbyl 2,6-dipalmitate inhibits biofilm formation and virulence in methicillin-resistant Staphylococcus aureus and prevents triacylglyceride accumulation in Caenorhabditis elegans

Sivasamy Sethupathy, Loganathan Vigneshwari, Alaguvel Valliammai, Krishnaswamy Balamurugan, Shunmugiah Karutha Pandian
<span title="">2017</span> <i title="Royal Society of Chemistry (RSC)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/x6heqyfrkfhzlnbbt24hnmjoda" style="color: black;">RSC Advances</a> </i> &nbsp;
In the present study, the antibiofilm, antipathogenic and anticarotenogenic potential of l-ascorbyl 2,6-dipalmitate (ADP) against methicillin-resistant Staphylococcus aureus (MRSA) has been evaluated.  ...  Furthermore, human stearoyl-coenzyme A desaturase-1 (SCD1) has been proven as a druggable target to design therapeutic agents to treat metabolic diseases, and hence SDC1 was also included in the molecular  ...  are given as ESI. † Molecular docking analysis The crystal structures of dehydroxysqualene synthase CrtM (ID: 2ZCO) and stearoyl-coenzyme A desaturase-1 (ID: 4ZYO) were retrieved from the protein data  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1039/c7ra02934a">doi:10.1039/c7ra02934a</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/nyju4hottvhulmab3qz6b23tei">fatcat:nyju4hottvhulmab3qz6b23tei</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190427020216/https://pubs.rsc.org/en/content/articlepdf/2017/ra/c7ra02934a" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/f5/e9/f5e9fa7387d4630d519ebcc4875cdecb04829027.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1039/c7ra02934a"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Preventive and Prophylactic Mechanisms of Action of Pomegranate Bioactive Constituents

Monica Viladomiu, Raquel Hontecillas, Pinyi Lu, Josep Bassaganya-Riera
<span title="">2013</span> <i title="Hindawi Limited"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/zncaxvmd7zbqjjpq55yaq6a3ay" style="color: black;">Evidence-Based Complementary and Alternative Medicine</a> </i> &nbsp;
Several studies investigate its bioactive components as a means to associate them with a specific beneficial effect and develop future products and therapeutic applications.  ...  constituents of pomegranate as well as drugs.  ...  Acknowledgments This work was supported by funds of the Nutritional Immunology and Molecular Medicine Laboratory.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1155/2013/789764">doi:10.1155/2013/789764</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23737845">pmid:23737845</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3657449/">pmcid:PMC3657449</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/auu7rhpxdvbcfp22fkzetna4va">fatcat:auu7rhpxdvbcfp22fkzetna4va</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190223191933/http://pdfs.semanticscholar.org/4bf5/610add004d411fe2ccf7f497d2166b091156.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/4b/f5/4bf5610add004d411fe2ccf7f497d2166b091156.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1155/2013/789764"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> hindawi.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657449" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Caenorhabditis elegans as a model organism in obesity research

Aneta Dyczkowska, Agnieszka Chabowska-Kita
<span title="">2021</span> <i title="Termedia Sp. z.o.o."> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/6r7cwl4e6bc6bnddwmbzhihwye" style="color: black;">BioTechnologia</a> </i> &nbsp;
Obesity is a global health problem associated with many comorbidities such as type 2 diabetes and cancer.  ...  Like in humans, fat storage in C. elegans depends on the interaction of genetic and environmental factors such as diet, microbiota and ambient temperature.  ...  The gut microbiota plays a crucial role in maintaining homeostasis through modulation of the intestinal digestion, production of vitamins B and K, maintenance of structural integrity of the gut mucosal  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5114/bta.2021.109094">doi:10.5114/bta.2021.109094</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/pervpaoww5fqjk6mpgq4xw7svi">fatcat:pervpaoww5fqjk6mpgq4xw7svi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20211206010802/http://www.biotechnologia-journal.org/Journal/-85/pdf-45136-10?filename=BTA" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/21/4f/214f99d892dc0efd076560dfaef29774d323a3c8.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5114/bta.2021.109094"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a>

Magnetic-Assisted Treatment of Liver Fibrosis

Kateryna Levada, Alexander Omelyanchik, Valeria Rodionova, Ralf Weiskirchen, Matthias Bartneck
<span title="2019-10-19">2019</span> <i title="MDPI AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3iichab3fbz7jq46o55l6trkq" style="color: black;">Cells</a> </i> &nbsp;
Hepatic fibrosis still remains a major burden on the global health systems.  ...  Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are considered the main cause of liver fibrosis.  ...  bile acid receptor 1 (GPBAR1) Aramchol An orally active fatty acid bile acid conjugate that inhibits stearoyl coenzyme A desaturase 1 (SCD1) Saroglitazar Agonist of PPARα (and PPARγ) Lanifibranor  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/cells8101279">doi:10.3390/cells8101279</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31635053">pmid:31635053</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6830324/">pmcid:PMC6830324</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/b4jivbdi45b4fajewus6ylpiyu">fatcat:b4jivbdi45b4fajewus6ylpiyu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200208084009/https://res.mdpi.com/d_attachment/cells/cells-08-01279/article_deploy/cells-08-01279.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/b8/93/b89312378eba3c02b4817ea31c726d8351166eeb.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/cells8101279"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> mdpi.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830324" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

SteatoNet- Modelling steatosis identifies candidate systemic flux distribution deregulations [article]

Adviti Naik, Damjana Rozman, Ales Belic
<span title="2013-09-05">2013</span> <i > arXiv </i> &nbsp; <span class="release-stage" >pre-print</span>
as a primary investigative tool for hypotheses generation and exploring related metabolic diseases.  ...  The unique validated model is based on steady-state analysis of ordinary differential equations that allows investigation of systemic behaviour in the absence of estimated kinetic parameters.  ...  Stearoyl CoA knockout Stearoyl CoA desaturase (SCD) is a rate-limiting delta-9 desaturase enzyme involved in lipogenesis [33, 34] .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1309.1316v1">arXiv:1309.1316v1</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/rhqlbcvqijbx7o2osgghrztd3m">fatcat:rhqlbcvqijbx7o2osgghrztd3m</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200830220244/https://arxiv.org/ftp/arxiv/papers/1309/1309.1316.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/d6/7d/d67d28110c01ca174437d83ae0861b724aaa372d.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener" href="https://arxiv.org/abs/1309.1316v1" title="arxiv.org access"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> arxiv.org </button> </a>

Quantitative Proteomic Analysis of BHK-21 Cells Infected with Foot-and-Mouth Disease Virus Serotype Asia 1

Hui-Chen Guo, Ye Jin, Shi-Chong Han, Shi-Qi Sun, Yan-Quan Wei, Xian-Ji Liu, Xia Feng, Ding Xiang Liu, Xiang-Tao Liu, Dong-Yan Jin
<span title="2015-07-10">2015</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a> </i> &nbsp;
Four structural proteins, VP1, VP2, VP3, and VP4, form the natural empty capsid with 60 copies of each protein.  ...  changes in BHK-21 cells infected with FMDV serotype Asia 1.  ...  Dan Yan for analysis of some results. Author Contributions Conceived and designed the experiments: HCG DXL XTL SQS. Performed the experiments: HCG YJ SCH YQW XJL. Analyzed the data: HCG XJL.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0132384">doi:10.1371/journal.pone.0132384</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26161868">pmid:26161868</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4498813/">pmcid:PMC4498813</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/dlsakzz7krge5h3afb47u2dwpu">fatcat:dlsakzz7krge5h3afb47u2dwpu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20171011010202/http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0132384&amp;type=printable" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/38/72/3872c89bff429e4187b808190b729e31b26bf76c.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0132384"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> plos.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498813" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Pharmacological Properties, Molecular Mechanisms, and Pharmaceutical Development of Asiatic Acid: A Pentacyclic Triterpenoid of Therapeutic Promise

Mohamed Fizur Nagoor Meeran, Sameer N. Goyal, Kapil Suchal, Charu Sharma, Chandragouda R. Patil, Shreesh K. Ojha
<span title="2018-09-04">2018</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/qigargnicncadmdn56ei23yjnu" style="color: black;">Frontiers in Pharmacology</a> </i> &nbsp;
Asiatic acid (AA) is a naturally occurring aglycone of ursane type pentacyclic triterpenoids.  ...  The review also also discusses the challenges and prospects on the pharmaceutical development of AA such as pharmacokinetics, physicochemical properties, analysis and structural modifications, and drug  ...  ACKNOWLEDGMENTS The authors are supported from grants provided by University Program for Advanced Research and Centre Based Interdisciplinary grants from United Arab Emirates University, United Arab Emirates  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fphar.2018.00892">doi:10.3389/fphar.2018.00892</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30233358">pmid:30233358</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6131672/">pmcid:PMC6131672</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/2ixqfg55izh23i4vgi3whnuhna">fatcat:2ixqfg55izh23i4vgi3whnuhna</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190218195644/http://pdfs.semanticscholar.org/0fc8/9d3a51d2226e2c35890a6b4d83b4a83c0613.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/0f/c8/0fc89d3a51d2226e2c35890a6b4d83b4a83c0613.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fphar.2018.00892"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131672" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Srx [chapter]

<span title="">2018</span> <i title="Springer International Publishing"> Encyclopedia of Signaling Molecules </i> &nbsp;
Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E.  ...  Toyoshima for allowing to use images and legends of Fig. 1 from his review article (Toyoshima 2009). Acknowledgments I would like to thank Ms. Kae Suzuki for reading manuscript.  ...  Funding This project was funded by the Japan Society for the Promotion of Science KAKENHI [20405020].  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/978-3-319-67199-4_103647">doi:10.1007/978-3-319-67199-4_103647</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/menzysrmvvgzhpkgxd2zh33vhq">fatcat:menzysrmvvgzhpkgxd2zh33vhq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180725021602/https://link.springer.com/content/pdf/10.1007%2F978-3-319-67199-4_103647.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/978-3-319-67199-4_103647"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a>

Sphingomyelinase, Acidic [chapter]

Nadine Beckmann, Erich Gulbins, Katrin Anne Becker, Alexander Carpinteiro
<span title="">2018</span> <i title="Springer International Publishing"> Encyclopedia of Signaling Molecules </i> &nbsp;
Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E.  ...  Toyoshima for allowing to use images and legends of Fig. 1 from his review article (Toyoshima 2009). Acknowledgments I would like to thank Ms. Kae Suzuki for reading manuscript.  ...  Funding This project was funded by the Japan Society for the Promotion of Science KAKENHI [20405020].  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/978-3-319-67199-4_101873">doi:10.1007/978-3-319-67199-4_101873</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/v7lv4dvmw5cr7ou7gafatkbq5i">fatcat:v7lv4dvmw5cr7ou7gafatkbq5i</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180725021602/https://link.springer.com/content/pdf/10.1007%2F978-3-319-67199-4_103647.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/978-3-319-67199-4_101873"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a>

Canadian Nutrition Society: Scientific Abstracts from the 8th Annual Scientific Meeting / Société canadienne de nutrition : Résumés scientifiques de la 8e réunion scientifique annuelle

<span title="">2017</span> <i title="Canadian Science Publishing"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ji5nh6isuzgwvotdvdfsxmam2u" style="color: black;">Applied Physiology, Nutrition and Metabolism</a> </i> &nbsp;
Introduction: High levels of Stearoyl-CoA Desaturase-1 (SCD1) expression have been reported in breast cancer (BC).  ...  We investigated the effects of diets high or low in omega (n)-3 polyunsaturated fatty acids (PUFA) on cerebellar fatty acid composition, and the mRNA expression of stearoyl CoA-desaturase-1 (SCD1), myelin-basic  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1139/apnm-2017-0134">doi:10.1139/apnm-2017-0134</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28485633">pmid:28485633</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/sdqlfiwiifgvdckp54koagvmqq">fatcat:sdqlfiwiifgvdckp54koagvmqq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200322235032/https://tspace.library.utoronto.ca/bitstream/1807/77111/1/apnm-2017-0134.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/4e/05/4e052bee1eda0e52f0326f0ee6b6c6fcfef2b7f3.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1139/apnm-2017-0134"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Thesis: Characterization of neutral lipid-deficient strains of Saccharomyces cerevisiae

Jeanne Garbarino
<span title="2012-04-13">2012</span> <i title="Figshare"> Figshare </i> &nbsp;
This is my thesis, entitled "Characterization of neutral lipid deficient strains of Saccharomyces cerevisiae." It was deposited into the Columbia University library in March 2008.  ...  The OLE1 gene has sequence conservation with the human stearoyl-CoA desaturase (SCD1 (24) ) and is likely equivalent in function since lesions in yeast OLE1 can be functionally complemented by expression  ...  of rat SCD1 (25) .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.6084/m9.figshare.91617">doi:10.6084/m9.figshare.91617</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/wte2rob3vrb7tpbgmdvagedf64">fatcat:wte2rob3vrb7tpbgmdvagedf64</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200215221931/https://s3-eu-west-1.amazonaws.com/pfigshare-u-files/90745/Introduction.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/1a/a5/1aa50ea1e5c0ded7fb27ca06861d1136d45d65b4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.6084/m9.figshare.91617"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> figshare.com </button> </a>

Abstracts from the 13th International Conference on Cerebral Vascular Biology (CVB 2019)

<span title="">2019</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/o7tyfoms2jcrbialut4jkepwoy" style="color: black;">Fluids and Barriers of the CNS</a> </i> &nbsp;
Also, in vitro BACE1-KD prevented the proinflammatory response and AT-8 in stearoyl-coenzyme A desaturase 1 (SCD1) and fatty acid desaturase 6 (FADS6) dependentmanner in an in vitro model by glutamate  ...  Objectives: The C-terminally truncated amyloid beta-peptide (Aβ) isoform, Aβ34, is an important intermediate product of enzymatic Aβ degradation and has the potential to be used as a biomarker of impaired  ...  (3.5 m/s to a depth of 1 mm).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/s12987-019-0135-8">doi:10.1186/s12987-019-0135-8</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/efb3m5hoajczbjg3anycabovva">fatcat:efb3m5hoajczbjg3anycabovva</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200217033744/https://fluidsbarrierscns.biomedcentral.com/track/pdf/10.1186/s12987-019-0135-8" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/5c/ec/5cec5e252184c672f75df628e8bea880859f9c39.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/s12987-019-0135-8"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a>

MOESM6 of Claudin-12 is not required for blood–brain barrier tight junction function

Mariana Castro Dias, Caroline Coisne, Pascale Baden, Gaby Enzmann, Lillian Garrett, Lore Becker, Sabine Hölter, Martin Hrabě De Angelis, Urban Deutsch, Britta Engelhardt
<span title="2019-09-12">2019</span> <i title="figshare"> Figshare </i> &nbsp;
Complete phenotyping report of claudin-12lacZ/lacZknock-in C57BL/6J mice.  ...  fatty acids -10.99 Cfd complement factor D (adipsin) -10.77 Adipoq adiponectin, C1Q and collagen domain containing -10.13 Car3 carbonic anhydrase 3 -14 Scd1 stearoyl-Coenzyme A desaturase  ...  This response is recorded as a series of vertex positive waves which are generated by different auditory structures.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.6084/m9.figshare.9808874.v1">doi:10.6084/m9.figshare.9808874.v1</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/yw6og7npe5ds5g2ofhipyp2deu">fatcat:yw6og7npe5ds5g2ofhipyp2deu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200217005340/https://s3-eu-west-1.amazonaws.com/pstorage-npg-968563215/17599880/12987_2019_150_MOESM6_ESM.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/74/4d/744d0dd2b4d432b854dfcc6bb017771870c70ec3.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.6084/m9.figshare.9808874.v1"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> figshare.com </button> </a>

Auxins [chapter]

<span title="">2008</span> <i title="Springer Netherlands"> Encyclopedia of Genetics, Genomics, Proteomics and Informatics </i> &nbsp;
▶host-pathogen relationship, ▶ribonuclease L A ˚(angström): A unit of length, 1/10 of 1 nm; 10 −7 mm.  ...  A6: Agrobacterium tumefaciens strain with a Ti plasmid coding for octopine production in the plant cell.  ...  encoding stearoyl-CoA desaturase 1 and Scd2 coding for stearoyl-CoA desaturase 2.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/978-1-4020-6754-9_1408">doi:10.1007/978-1-4020-6754-9_1408</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/k6mgbxvlkndzbp66zjgpgjyle4">fatcat:k6mgbxvlkndzbp66zjgpgjyle4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180728154711/https://link.springer.com/content/pdf/10.1007%2F978-1-4020-6754-9_723.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/978-1-4020-6754-9_1408"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a>
&laquo; Previous Showing results 1 &mdash; 15 out of 35 results