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IQ was negatively correlated with motor impairment, although the correlation was mostly accounted for by AS Ss. 50% of AS Ss and 67% of autistic Ss showed a clinically significant level of motor impair ... AS and autistic Ss did not differ on either total or subscale impairment scores. ...
greater levels of autistic traits, which seem to be distributed in a continuum featuring the highest levels among BD subjects. ... Correlation and regression analyses highlighted specific patterns of association among AdAS Spectrum domains, RRS, and suicidality in each clinical group. (4) Conclusions: Both BPD and BD individuals show ... Institutional Review Board Statement: The study was conducted according to the guidelines of the Declaration of Helsinki, and approved by the Institutional Ethics Committee of Azienda Ospedialiera Universitaria ...doi:10.3390/brainsci11050621 pmid:34066194 fatcat:jxoqvhgokvfi5dv3jle7edl44a
To date, few cases of 3p proximal interstitial deletions have been reported and the phenotype and genotype correlation is not well understood. ... We compare our case with previously well-defined patients reported in the literature and databases. ... Data discussed in this paper were obtained from the ISCA Consortium database (http://www.iscaconsortium .org/), with this information having been generated using NCBI's database of genomic structural variation ...doi:10.1155/2015/876348 pmid:26075115 pmcid:PMC4446465 fatcat:4xinsexkhzhp3ok7qe4fmbmge4
The authors measured odor detection threshold and odor identification in 12 males with Asperger's syndrome and 12 matched control subjects. ... Relative to control subjects, Asperger's syndrome subjects were not impaired at odor detection but were significantly impaired at olfactory identification. ... temporal lobe structures and prefrontal cortex in autistic spectrum disorders. ...doi:10.1176/jnp.15.1.105 pmid:12556580 fatcat:bsaenovkgjb4thrpqu3pk542wa
Epilepsy & Behavior
in the presence of ID, and laws requiring provision of services for children with autism. ... While these specific forms of epilepsy carry a higher-than-expected risk of autism, most, if not all, of the association may be due to intellectual disability (ID). ... Acknowledgments Funding: ATB was supported by a grant from the National Institutes of Health, National Institute of Neurological Disorders and Stroke R37-NS31146 ...doi:10.1016/j.yebeh.2012.01.015 pmid:22381386 pmcid:PMC3307824 fatcat:pzh2drazbrg3xlobacwjchsi2y
Here a recent body of research in genetics and epidemiology is presented to examine a dimensional reconceptualization of autistic social impairment-as manifested in clinical autistic syndromes, the broader ... Autism, like intellectual disability, represents the severe end of a continuous distribution of developmental impairments that occur in nature, that are highly inherited, and that are orthogonally related ... In this review we focus on autistic social impairment as a core feature of autistic syndromes but recognize that language impairments and stereotypic behaviors may exhibit distributions and patterns of ...doi:10.1203/pdr.0b013e318212ec6e pmid:21289537 pmcid:PMC3086844 fatcat:nmme4hfvjrgfxpntzp2kmlsbdi
Several studies showed a different symptom structure underlying the spectrum of autistic-like disorders from the behaviour triad as mentioned in the DSM-IV. ... Nevertheless, the stability of the model needs further examination in a larger group of individuals with disorders in the autism spectrum, and with varying degrees of intellectual functioning. ... Acknowledgements This research was supported by grants from the Netherlands Organisation for Health Research and Development (ZON/MW) and from the Korczak Foundation for autism and related disorders. ...doi:10.1111/j.1469-7610.2005.01434.x pmid:16405639 fatcat:jvofj4gw5rfifamihffuvw4kcm
Severity of ASD traits in individuals and parents did not correlate with suicidal risk. Some dimensions of resilience were protective in terms of repulsion by life and attraction to death. ... to 18 adolescents with BD and suicidal ideation or attempts without ASD (BD-noASD-S), using a structured assessment methodology. ... Acknowledgments: The authors wish to thank all the participants, the adolescent and their parents Conflicts of Interest: Gabriele Masi was in advisory boards for Angelini, received grants from Lundbeck ...doi:10.3390/brainsci10100750 pmid:33080887 pmcid:PMC7603180 fatcat:y5sb6qyy4rh3paqjccl7d27rwy
Each group consisted of 7 mothers, 4 fathers, and 1 sister of autistic children and adolescents. ... While many studies can be criticized on methodological grounds, there is good evidence for an impair- ment in the spontaneous symbolic play of autistic children, an impairment that appears to extend to ...
Acknowledgements The present study was supported by the Centre for Child and Adolescent Mental Health and Welfare, Uni Health, Uni Research, Bergen, Norway, and was also funded by the University of Bergen ... We are grateful to the children, parents, and teachers participating in the Bergen Child Study (BCS), and to the BCS project group for making the study possible. ... (WISC-III) The WISC-III is designed to assess intellectual abilities in children and adolescents aged 6-16 years. ...doi:10.1016/j.rasd.2013.12.001 fatcat:cjhs5x6jbnanpak47zxoelpi7y
Few studies have examined the relationship between autistic symptomatology and competence in independent living skills in adolescents and young adults with fragile X syndrome (FXS). ... Results showed that higher levels of autistic symptomatology were associated with lower levels of competence in independent living skills in individuals with FXS, but not in controls. ... Acknowledgments This study was supported by grant numbers MH50047 (PI Allan Reiss) and K08MH081998 (PI Scott Hall) from the National Institute of Mental Health, a gift from the Canel Family, and the Fonds ...doi:10.1007/s10803-014-2342-0 pmid:25518824 pmcid:PMC4548879 fatcat:ztsu7uc4gfbybonezxmlboekni
light on such etiologic factors; thus, the current study examined prodromal symptoms and autistic features in samples of 22q11DS and SPD subjects using standardized diagnostic measures, including the ... The results suggest that childhood autistic features are less continuous with subsequent prodromal signs in 22q11DS patients relative to those with SPD, and the findings highlight the importance of studying ... between autistic features and prodromal symptoms in a sample of SPD adolescents and a sample of individuals with 22q11DS. ...doi:10.1037/a0028373 pmid:22686870 fatcat:bbdo2uqm5fgprevd6ni63pj7wy
Autism - Open Access
For example, in a sample of 58 children and adolescents with catatonia  , 18 (31%) had a history of developmental disorder, i.e., autism spectrum disorder, intellectual disability or neurodevelopmental ... , some autistic features, and medical and behavioral abnormalities that are specific to the genetic defect. ...doi:10.4172/2165-7890.1000e114 fatcat:arrswoea7bfo7l4bxiops6rqzq
Abnormalities in melatonin physiology may be involved or closely linked to the pathophysiology and behavioral expression of autistic disorder, given its role in neurodevelopment and reports of sleep-wake ... In this article, first we review the studies on melatonin levels and the treatment studies of melatonin in autistic disorder. ... Furthermore, nocturnal excretion of 6-SM was significantly negatively correlated with severity of autistic impairments in verbal communication and play [58, 59] . ...doi:10.3390/ijms141020508 pmid:24129182 pmcid:PMC3821628 fatcat:ohn47adpirf2vo4tdqofqys3tq
The study examines the validity of the PHQ-9 for detecting major depressive disorder (MDD) in autistic youths. ... Background Autistic adolescents have greater predisposition to depression and suicidality than neurotypical adolescents. Early detection is essential for timely treatment. ... Acknowledgements We thank the families and patients who participated in this research, and the research team members, psychiatrists, psychologists and medical social workers of the Child Guidance Clinic ...doi:10.1186/s12888-021-03556-w pmid:34772391 pmcid:PMC8588623 fatcat:fyk6qopx2zc77i5w33v6ud5lm4
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