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A Harmonized Atlas of Spinal Cord Cell Types and Their Computational Classification [article]

Daniel E. Russ, Ryan B. Patterson Cross, Li Li, Stephanie C. Koch, Kaya J.E. Matson, Ariel Levine
2020 bioRxiv   pre-print
To harness the exciting potential of single cell data for the study of the mouse spinal cord, we have created a harmonized atlas of spinal cord transcriptomic cell types that unifies six independent and  ...  This work provides a comprehensive resource with unprecedented resolution of spinal cord cell types and charts a path forward for how to utilize transcriptomic data to expand our knowledge of spinal cord  ...  cell types -a dataset similar in scale and complexity to the harmonized analysis here 18 .  ... 
doi:10.1101/2020.09.03.241760 fatcat:q7ponewf7vgphnndiqn4ucizna

Harmonizing Databases? Evaluating Effectiveness of A Statewide Public Mental Health Reentry Program [English and Spanish versions]

Stephanie W. Hartwell, Xiaogang Deng, William H. Fisher, Carl E. Fulwiler, Debra A. Pinals
2012 Psychiatry Information in Brief  
A Publication of the Center for Mental Health Services Research A Massachusetts Department of Mental Health Research Center of Excellence Research in the Works Research Team: Stephanie W.  ...  " Data -This study will establish a combined dataset "harmonizing" existing administrative databases to evaluate the effectiveness of the Massachusetts Department of Mental Health's Forensic Transition  ... 
doi:10.7191/pib.1072 fatcat:3mgmi2roxvhelmbsxfriwgqzfi

A discontinuous Galerkin method on refined meshes for the two-dimensional time-harmonic Maxwell equations in composite materials

Stephanie Lohrengel, Serge Nicaise
2007 Journal of Computational and Applied Mathematics  
In this paper, a discontinuous Galerkin method for the two-dimensional time-harmonic Maxwell equations in composite materials is presented.  ...  Optimal error estimates in a discrete energy norm and in the L 2 -norm are proved in the case where the exact solution is singular.  ...  For the time-harmonic Maxwell equations, different approaches, based on a classical or mixed formulation, have been presented for example in [12, 13, 18] .  ... 
doi:10.1016/j.cam.2006.05.020 fatcat:sudzprxpvrhopaa5j7lq24glu4

A Daily Oscillation in the Fundamental Frequency and Amplitude of Harmonic Syllables of Zebra Finch Song

William E. Wood, Peter J. Osseward, Thomas K. Roseberry, David J. Perkel, Stephanie Ann White
2013 PLoS ONE  
The FF and amplitude of harmonic syllables rises across the morning, reaching a peak near mid-day, and then falls again in the late afternoon until sleep.  ...  By undertaking a quantitative analysis of the fundamental frequency (FF) and amplitude of hundreds of zebra finch syllables per animal per day, we find that zebra finch song follows a previously undescribed  ...  We also thank two anonymous reviewers for helpful comments, particularly involving a potential link between amplitude and FF.  ... 
doi:10.1371/journal.pone.0082327 pmid:24312654 pmcid:PMC3846747 fatcat:3wzpmoa4ibgsxfipwoqctgovsq

Harmonizing databases? Developing a quasi-experimental design to evaluate a public mental health re-entry program

Stephanie W. Hartwell, Xiaogang Deng, William Fisher, Carl Fulwiler, Usha Sambamoorthi, Craig Johnson, Debra A. Pinals, Lisa Sampson, Julianne Siegfriedt
2012 Evaluation and Program Planning  
The program began in 1998 with the goal of transitioning offenders with SMI released from state and local correctional facilities utilizing a core set of transition activities.  ...  Our goal was to establish a combined dataset, since offenders with SMI have significant involvement with multiple agencies, "harmonizing" existing administrative databases to evaluate the Department of  ...  These examples demonstrate just some of the checks and multiple runs that need to be conducted as a result of the different databases, agencies, and information systems that we attempted to "harmonize"  ... 
doi:10.1016/j.evalprogplan.2012.02.001 pmid:22436598 pmcid:PMC3371126 fatcat:bfrwq2sz5zhbjf5zn5ezozd5ry

Assessment of Myocardial Perfusion by Harmonic Power Doppler Imaging at Rest and During Adenosine Stress

Sheila K. Heinle, Jennifer Noblin, Pam Goree-Best, Ana Mello, Guy Ravad, Stephanie Mull, Pradeep Mammen, Paul A. Grayburn
2000 Circulation  
Background-Harmonic power Doppler imaging (HPDI) is a novel technique for assessing myocardial perfusion by contrast echocardiography in humans.  ...  The persistence of absent or patchy myocardial perfusion by HPDI between rest and adenosine was interpreted as a fixed defect, whereas any decrease in perfusion grade was interpreted as a reversible defect  ...  First, it increases the sensitivity of HPDI and allows for removal of the tissue harmonic signal with a wall filter, albeit at a cost of a lower frame rate.  ... 
doi:10.1161/01.cir.102.1.55 pmid:10880415 fatcat:v6rkha7r6napbacx63hxlh5dxe

Developing a harmonized heat warning and information system for Ontario: a case study in collaboration

Dave Henderson, Louise Aubin, Kevin Behan, Hong Chen, Helen Doyle, Stephanie Gower, Melissa MacDonald, Carol Mee, Gregory R. A. Richardson, Greg Rochon, Mira Shnabel, Jay Storfer (+2 others)
2020 Canadian journal of public health  
This article describes the collaborative process and key steps in developing a harmonized Heat Warning and Information System (HWIS) for Ontario.  ...  In 2011, stakeholders identified the need to develop a harmonized system across Ontario to improve heat warning services, warning criteria, and health messaging.  ...  A complete list of these individuals is provided in the Supplementary Material.  ... 
doi:10.17269/s41997-020-00337-y pmid:32524507 pmcid:PMC7351991 fatcat:dbhtnubgvrhgldlpkwvobv3qhi

SARS-CoV-2 Cardiac Involvement in Young Competitive Athletes

Nathaniel Moulson, Bradley J. Petek, Jonathan A. Drezner, Kimberly G. Harmon, Stephanie A. Kliethermes, Manesh R. Patel, Aaron L. Baggish
2021 Circulation  
Conclusions: SARS-CoV-2 infection among young competitive athletes is associated with a low prevalence of cardiac involvement and a low risk of clinical events in short term follow-up.  ...  Accordingly, the diagnostic yield of CMR for SARS-COV-2 cardiac involvement was 4.2 times higher for a clinically indicated CMR (15/119,12.6%) versus a primary screening CMR (6/198,3.0%).  ...  [10] [11] [12] [13] A subsequent study in professional athletes undergoing RTP cardiac testing reported a lower prevalence of cardiac involvement (0.6%) when utilizing a testing strategy of 12-lead  ... 
doi:10.1161/circulationaha.121.054824 pmid:33866822 fatcat:t7nzjews3nhctbqqk7ebyo6zoi

A harmonized atlas of mouse spinal cord cell types and their spatial organization

Daniel E. Russ, Ryan B. Patterson Cross, Li Li, Stephanie C. Koch, Kaya J. E. Matson, Archana Yadav, Mor R. Alkaslasi, Dylan I. Lee, Claire E. Le Pichon, Vilas Menon, Ariel J. Levine
2021 Nature Communications  
We validate a combinatorial marker code for each neuronal cell type and map their spatial distributions in the adult spinal cord.  ...  Here, we generate an atlas of spinal cell types based on single-cell transcriptomic data, unifying the available datasets into a common reference framework.  ...  cell types-a dataset similar in scale and complexity to the harmonized analysis here 125 .  ... 
doi:10.1038/s41467-021-25125-1 pmid:34588430 pmcid:PMC8481483 fatcat:y225uai6r5f2lgn573thoyxmfu

Quick guide on radiology image pre-processing for deep learning applications in prostate cancer research

Samira Masoudi, Stephanie A. Harmon, Sherif Mehralivand, Stephanie M. Walker, Harish Raviprakash, Ulas Bagci, Peter L. Choyke, Baris Turkbey
2021 Journal of Medical Imaging  
There are plenty of publicly available algorithms, each designed to address a different task of computer vision in general.  ...  Approach: To be able to employ the publicly available algorithms for clinical purposes, we must make a meaningful pixel/voxel representation from medical images which facilitates the learning process.  ...  There is a limit to direct presentation of these values as an image to a radiologist.  ... 
doi:10.1117/1.jmi.8.1.010901 pmid:33426151 pmcid:PMC7790158 fatcat:azor7byitvhs3b4bjezu5agxby

Adipose Tissue Segmentation in Unlabeled Abdomen MRI using Cross Modality Domain Adaptation [article]

Samira Masoudi, Syed M. Anwar, Stephanie A. Harmon, Peter L. Choyke, Baris Turkbey, Ulas Bagci
2020 arXiv   pre-print
Although computed tomography (CT) is a highly sensitive modality to segment body fat, it involves ionizing radiations which makes magnetic resonance imaging (MRI) a preferable alternative for this purpose  ...  Our method does not require supervised labeling of MR scans, instead, we utilize a cycle generative adversarial network (C-GAN) to construct a pipeline that transforms the existing MR scans into their  ...  A few representative examples of segmentation results are presented in Fig. 6. 20814, USA ismail.turkbey@nih.gov Harmon is with Clinical Research Directorate, Frederick National Laboratory for Cancer  ... 
arXiv:2005.05761v1 fatcat:ea3s2rv7dfhslmyqj7jagzic7u

Catalyzing Knowledge-Driven Discovery in Environmental Health Sciences through a Community-Driven Harmonized Language

Stephanie D Holmgren, Rebecca R Boyles, Ryan D Cronk, Christopher G Duncan, Richard K Kwok, Ruth M Lunn, Kimberly C Osborn, Anne E Thessen, Charles P Schmitt
2021 International Journal of Environmental Research and Public Health  
We describe a community initiative whose mission was to advance integrative environmental health sciences research via the development and adoption of a harmonized language.  ...  The results of prior workshops to advance a harmonized environmental health language demonstrate that future efforts should be sustained and grounded in scientific need.  ...  Introduction The use of a harmonized language to describe scientific methods and discoveries is well recognized as being critical for a variety of needs, including searching the literature, integrating  ... 
doi:10.3390/ijerph18178985 pmid:34501574 pmcid:PMC8430534 fatcat:5kamp2dsznfmvirpn66aqhy4im

Harmonization of Food-Frequency Questionnaires and Dietary Pattern Analysis in 4 Ethnically Diverse Birth Cohorts

Russell J de Souza, Michael A Zulyniak, Dipika Desai, Mateen R Shaikh, Natalie C Campbell, Diana L Lefebvre, Milan Gupta, Julie Wilson, Gita Wahi, Stephanie A Atkinson, Koon K Teo, Padmaja Subbarao (+5 others)
2016 Journal of Nutrition  
(21) 60 In preparation for investigations into the role of maternal nutrition on maternal and 61 newborn outcomes in a multiethnic birth cohort consortium, we developed an approach to 62 harmonize dietary  ...  A 183 design feature of the mAHEI (and other indexes, such as the Healthy Eating Index FFQs were harmonized across 4 cohorts (SUPPLEMENTAL TABLE 1). 197 The dimensionality of the food group matrix was  ... 
doi:10.3945/jn.116.236729 pmid:27708121 fatcat:jnmvenbt3nej5g7owy6mkqilsm

Molecular image-directed biopsies: improving clinical biopsy selection in patients with multiple tumors

Stephanie A Harmon, Michael J Tuite, Robert Jeraj
2016 Physics in Medicine and Biology  
In a prospective study, we were able to successfully plan, develop, and implement this technique for the selection of a pre-treatment biopsy location.  ...  After identifying candidates, biopsy feasibility was evaluated by a physician and confirmed for 90% (32/36) of high-ranking lesions, of which all top choices were confirmed.  ...  This research is partly funded by the Prostate Cancer Foundation's A. David Mazzone-PCF Challenge Award.  ... 
doi:10.1088/0031-9155/61/20/7282 pmid:27694707 pmcid:PMC5288736 fatcat:bjd57tflebcvngmfu6mxzkpv5a

Artificial intelligence at the intersection of pathology and radiology in prostate cancer

Stephanie A. Harmon, Sena Tuncer, Thomas Sanford, Peter L. Choyke, Baris Turkbey
2019 Diagnostic and Interventional Radiology  
Multiparametric magnetic resonance imaging (mpMRI) has become a well-established clinical tool for detecting and localizing prostate cancer.  ...  Pathologic grading plays a key role in prostate cancer risk stratification and treatment selection, traditionally assessed from systemic core needle biopsies sampled throughout the prostate gland.  ...  Turkish Society of Radiology also requires a detailed overview of how you intend to use the material (i.e., in a book or a journal) and when.  ... 
doi:10.5152/dir.2019.19125 pmid:31063138 pmcid:PMC6521904 fatcat:6hykk7gaundrbdwj4tmfiuojqi
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