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Spot the difference: comparing results of analyses from real patient data and synthetic derivatives

Randi E Foraker, Sean C Yu, Aditi Gupta, Andrew P Michelson, Jose A Pineda Soto, Ryan Colvin, Francis Loh, Marin H Kollef, Thomas Maddox, Bradley Evanoff, Hovav Dror, Noa Zamstein (+2 others)
2020 JAMIA Open  
Methods We explored three use cases and tested the robustness of synthetic data by comparing the results of analyses using synthetic derivatives to analyses using the original data using traditional statistics  ...  , machine learning approaches, and spatial representations of the data.  ...  ACKNOWLEDGEMENTS This work was supported by a grant from the St. Louis Children's Hospital Foundation (J.P.). The authors wish to thank J.P. for his assistance in creating figures.  ... 
doi:10.1093/jamiaopen/ooaa060 pmid:33623891 pmcid:PMC7886551 fatcat:nrxuv2b3y5dgha7a5xasl3kew4

Word Spotting in the Wild [chapter]

Kai Wang, Serge Belongie
2010 Lecture Notes in Computer Science  
Requiring so many carefully annotated examples for so many different languages may not be feasible via human annotation alone. Figure 5 . 5 2 highlights the intuition behind our work.  ...  LIST OF FIGURES Word spotting overview. This is an illustration of a word spotting system with two steps: text detection [12] and word recognition.  ... 
doi:10.1007/978-3-642-15549-9_43 fatcat:wronhivlozgjdmsgkdfnsr7xme

How the universe got its spots

Janna Levin, Evan Scannapieco, Giancarlo de Gasperis, Joseph Silk, John D. Barrow
1998 Physical Review D, Particles and fields  
The global geometry of the universe can be revealed in the spatial distribution of these spots.  ...  The universe displays a three-dimensional pattern of hot and cold spots in the radiation remnant from the big bang.  ...  This research has been supported in part by grants from the NSF, DOE and the PPARC of the UK.  ... 
doi:10.1103/physrevd.58.123006 fatcat:dr6iodewa5cifji6gwiyot6m74

Illusory Contours Do Not Pass through the "Blind Spot"

Marianne Maertens, Stefan Pollmann
2007 Journal of Cognitive Neuroscience  
simulations (Wichmann & Hill, 2001a) for each psychometri RESULTS Accuracy Figure 2 shows the performance thresholds for the for both eyes and both tasks.  ...  The human optic disc has a diameter of about 2 mm on the retina, corresponding to a diameter of 5 to in terms of visual angle in the visual field.  ... 
doi:10.1162/jocn.2007.19.1.91 pmid:17214566 fatcat:4o2zkncs3rhkzioljpysl32a6u

Life cycle assessment of the new InnoRenew CoE research building – hot spots and the effects of methodological differences on the results for a wooden frame building

Erwin M. Schau, Eva Prelovšek Niemelä, Urban Kavka, Andreja Kutnar
2020 Zenodo  
Conference abstract for the 2020 Society of Wood Science and Technology International Convention.  ...  She is focused on the numerical simulations of wood and wood-based materials physical and mechanical behavior.  ...  Life cycle assessment of the new InnoRenew CoE research building -hot spots and the effects of methodological differences on the results for a wooden frame building The construction industry accounts for  ... 
doi:10.5281/zenodo.3960886 fatcat:ibzesaqxvjfahcoljapuwdxg6e

Blind Spot Detection for Safe Sim-to-Real Transfer

Ramya Ramakrishnan, Ece Kamar, Debadeepta Dey, Eric Horvitz, Julie Shah
2020 The Journal of Artificial Intelligence Research  
Our system learns models for predicting blind spots within unseen regions of the state space by combining techniques for label aggregation, calibration, and supervised learning.  ...  We also empirically analyze the biases of various feedback types and how these biases influence the discovery of blind spots.  ...  framework that leverages human feedback to learn a blind spot map of the target world, (3) evaluating our approach across two simulated domains, (4) assessing the biases of different types of human feedback  ... 
doi:10.1613/jair.1.11436 fatcat:xqsuk44t2jcgdlhrfmisc7thua

A compound-based computational approach for the accurate determination of hot spots

Lincong Wang, Yaqin Hou, Haihua Quan, Weiwei Xu, Yongli Bao, Yuxin Li, Yuan Fu, Shuxue Zou
2013 Protein Science  
while the accuracy of the current computational methods for hot-spot identification remains low.  ...  The hot spots of human ActRII first reported here may well become the focal points for the design of small molecule drugs that target the PPI.  ...  The accuracy of our PPI site search and hot-spot determination relies critically on the accuracy of GOLD that itself employs a genetic algorithm to optimize a protein-ligand scoring function.  ... 
doi:10.1002/pro.2296 pmid:23776011 pmcid:PMC3832042 fatcat:gonedrwuijdfpopxsfw5laiciy

Spotting expertise in the eyes: Billiards knowledge as revealed by gaze shifts in a dynamic visual prediction task

S. Crespi, C. Robino, O. Silva, C. de'Sperati
2012 Journal of Vision  
Thus, the eye movements of expert observers contained a clear signature of billiard expertise and documented empirically a strategy upgrade in visual problem solving from dynamic, analog simulation in  ...  They had to predict whether or not the ball would have hit the central skittle. Experts performed better than novices, in terms of both accuracy and response time.  ...  phase of the study.  ... 
doi:10.1167/12.11.30 pmid:23115218 fatcat:htqyhmwfo5hh7ff3vmtniqocke

Seeing the Difference between Cosmological Simulations

S. Haroz, K. Heitmann
2008 IEEE Computer Graphics and Applications  
of the system phase space distribution function while others simplify by distance. 5 Each simulation was run separately, and as a result of their implementation differences, every simulation produced  ...  Furthermore, visualizing the differences between multiple simulations can let scientists directly analyze the simulations' consistency.  ...  of the system phase space distribution function while others simplify by distance. 5 Each simulation was run separately, and as a result of their implementation differences, every simulation produced  ... 
doi:10.1109/mcg.2008.101 pmid:18753033 fatcat:psaqshwlnzbdjb5gum727rsm4q

Blind Spots and Mind Games: Performance, Motivation, and Emotion in the Films of Stanley Kubrick

Aaron Taylor
2016 The Velvet Light Trap  
Performances in Kubrick's work reveal the complications involved in positing narration as a rhetorical system with a priori claims to direct and accurate evaluative knowledge of characters.  ...  For Kubrick, narrative discourse is not a systemic correlative for authorial mastery over characters, and so, his actors help establish narrational patterns that collide with the intricacies of fictional  ...  Under the guise of a hoary ghost story adapted from Stephen King's best-selling novel, it upends numerous horror clichés, particularly the uncanny visualization of the imperceptible.  ... 
doi:10.7560/vlt7702 fatcat:conq2yuxtrbxjmn4qdrzuqzawq

Molecular Determinants Underlying Binding Specificities of the ABL Kinase Inhibitors: Combining Alanine Scanning of Binding Hot Spots with Network Analysis of Residue Interactions and Coevolution

Amanda Tse, Gennady M. Verkhivker, Fernando Rodrigues-Lima
2015 PLoS ONE  
In this work, molecular simulations and computational alanine scanning are combined with the network-based approaches to characterize molecular determinants underlying binding specificities of the ABL  ...  According to our results, Nilotinib binding may induce a significant network-bridging effect and enhance centrality of the hot spot residues that stabilize structural environment favored by the specific  ...  binding free energy may be gleaned from MD simulations of the WT system.  ... 
doi:10.1371/journal.pone.0130203 pmid:26075886 pmcid:PMC4468085 fatcat:lf2dzrruizai7fv35qh27s4kb4

Source localization of the EEG human brainwaves activities via all the different mother wavelets families for stationary wavelet transform decomposition [article]

Tarek Frikha
2019 arXiv   pre-print
The source localization of the human brain activities is an important resource for the recognition of cognitive state, medical disorders and a better understanding of the brain in general.  ...  In this study, we have compared 51 mother wavelets from 7 different wavelet families in a Stationary Wavelet transform (SWT) decomposition of an EEG signal.  ...  Abir Hadriche for their guidance and support during the development of this project.  ... 
arXiv:1911.01230v1 fatcat:tlqujw3jdret7dumoci5le3lsi

Leaf area index for biomes of the Eastern Arc Mountains: Landsat and SPOT observations along precipitation and altitude gradients

Marion Pfeifer, Alemu Gonsamo, Mathias Disney, Petri Pellikka, Rob Marchant
2012 Remote Sensing of Environment  
Spectral vegetation indices (VIs) extracted from Landsat Enhanced Thematic Mapper (ETM +) and Système Probatoire d'Observation de la Terre (SPOT) reflectance data were used, along with mean annual precipitation  ...  Implementing long-term MAP as a second predictor variable into the VI-LAI models significantly improved LAI predictions by up to 10% using the normalised difference vegetation index (NDVI), modified soil  ...  We acknowledge helpful assistance in the field from Simon Willcock at the University of Leeds. We thank the two anonymous reviewers for providing valuable comments on the manuscript.  ... 
doi:10.1016/j.rse.2011.11.009 fatcat:4fd7lkizerd4ndgv2heuao4ega

Analyzing the feasibility of a space-borne sensor (SPOT-6) to estimate the height of submerged aquatic vegetation (SAV) in inland waters

Luiz Henrique S. Rotta, Deepak R. Mishra, Fernanda S.Y. Watanabe, Thanan W.P Rodrigues, Enner H. Alcântara, Nilton N. Imai
2018 ISPRS journal of photogrammetry and remote sensing (Print)  
The model based on SPOT-6 data presented higher accuracy, with R 2 of 0.54 and RMSE of 0.29 m (NRMSE = 15%).  ...  Also to test different radiative transfer theory based bio-optical models for estimating SAV heights using SPOT-6 data.  ...  Acknowledgments The authors wish to thank the São Paulo  ... 
doi:10.1016/j.isprsjprs.2018.07.011 fatcat:q4tew426jrdxnaxlyj574co2om

Microhabitat Features at Mexican Spotted Owl Nest and Roost Sites in the Guadalupe Mountains

Timothy C. Mullet, James P. Ward
2010 The Journal of raptor research  
This volume consists of chapters on aspects of Mexican spotted owl natural history that were developed during preparation of the Mexican Spotted Owl Recovery Plan (Recovery Plan).  ...  The Mexican Spotted Owl Recovery Team and the Fish and Wildlife Service believe that these technical papers should, however, be available to anyone who would like a detailed account of subject matter contained  ...  Simple graphs and tabular summaries should be available via a menu system.  ... 
doi:10.3356/jrr-10-22.1 fatcat:okeacrsuwrefvg4u47we2beo7i
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