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Spatially-constrained probability distribution model of incoherent motion (SPIM) for abdominal diffusion-weighted MRI

Sila Kurugol, Moti Freiman, Onur Afacan, Jeannette M. Perez-Rossello, Michael J. Callahan, Simon K. Warfield
2016 Medical Image Analysis  
Further, we improve the robustness of the distribution parameter estimates by integrating spatial homogeneity prior into the probability distribution model of incoherent motion (SPIM) and by using the  ...  In this work, we propose a probability distribution model of incoherent motion that uses a mixture of Gamma distributions to fully characterize the multi-scale nature of diffusion within a voxel.  ...  Institutes of Health.  ... 
doi:10.1016/j.media.2016.03.009 pmid:27111049 pmcid:PMC4903917 fatcat:lqklwg2z2vc4vgc4m2ix2b2rri

Motion-robust parameter estimation in abdominal diffusion-weighted MRI by simultaneous image registration and model estimation

Sila Kurugol, Moti Freiman, Onur Afacan, Liran Domachevsky, Jeannette M. Perez-Rossello, Michael J. Callahan, Simon K. Warfield
2017 Medical Image Analysis  
Graphical abstract Keywords Diffusion-weighted imaging; motion compensation; abdomen; intra voxel incoherent motion model Kurugol et al.  ...  In this work, we introduce a new model of DW-MRI signal decay that explicitly accounts for motion.  ...  This spatially-constrained probability model of incoherent motion (SPIM) has been shown to characterize the entire scale of diffusion reflecting the tissue microstructure while increasing the precision  ... 
doi:10.1016/j.media.2017.04.006 pmid:28494271 pmcid:PMC5514879 fatcat:x6c54udtavaezdl3hb4b2bz2um

Motion Compensated Abdominal Diffusion Weighted MRI by Simultaneous Image Registration and Model Estimation (SIR-ME) [chapter]

Sila Kurugol, Moti Freiman, Onur Afacan, Liran Domachevsky, Jeannette M. Perez-Rossello, Michael J. Callahan, Simon K. Warfield
2015 Lecture Notes in Computer Science  
Non-invasive characterization of water molecule's mobility variations by quantitative analysis of diffusion-weighted MRI (DW-MRI) signal decay in the abdomen has the potential to serve as a biomarker in  ...  volumes along the diffusion weighting dimension.  ...  Signal decay model (Θ) estimation-We use the spatially constrained probability distribution model of slow and fast diffusion (SPIM) [4] to robustly estimate the fast and slow diffusion parameters of  ... 
doi:10.1007/978-3-319-24574-4_60 pmid:26550612 pmcid:PMC4636124 fatcat:l7vet6owh5hhlga4zgzwhkedni

Bifurcated Topological Optimization for IVIM

Shreyas Fadnavis, Stefan Endres, Qiuting Wen, Yu-Chien Wu, Hu Cheng, Serge Koudoro, Swati Rane, Ariel Rokem, Eleftherios Garyfallidis
2021 Frontiers in Neuroscience  
In this work, we shed light on the issue of estimating Intravoxel Incoherent Motion (IVIM) for diffusion and perfusion estimation by characterizing the objective function using simplicial homology tools  ...  Estimating the tissue microstructure from diffusion MRI is in itself an ill-posed and a non-linear inverse problem.  ...  Spatially-constrained probability distribution model of Publisher’s Note: All claims expressed in this article are solely those of the authors incoherent motion (SPIM) for abdominal diffusion-weighted  ... 
doi:10.3389/fnins.2021.779025 pmid:34975382 pmcid:PMC8714828 fatcat:6aer64poubdalettkkhdcpnfre

High-resolution fluorescence endomicroscopy for rapid evaluation of breast cancer margins

Khushi Vyas, Guang-Zhong Yang, Daniel Leff, Michael Hughes, Engineering And Physical Sciences Research Council
2019
The standard of care for surgical margin assessment is post-operative examination of histopathological tissue sections.  ...  It is the recommended treatment for a large number of patients with early stage disease or, in more advanced cases, following neoadjuvant chemotherapy.  ...  Mathematical model for piezoelectric tube deflection Several physically-based and experimentally derived models for the tube scanner are available in the literature [268, 272] .  ... 
doi:10.25560/68491 fatcat:yldijrsr2fctzdaf2goj7dc4ua