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An antenna-coupled split-ring resonator-based microwave sensor is introduced for biosensing applications. The sensor comprises a metallic ring with a slit and integrated monopole antennas on top of a dielectric substrate. The backside of the substrate is attached to a metallic plate. Integrated antennas are used to excite the device and measure its electromagnetic characteristics. The resonant frequency of the device is measured as 2.12 GHz. The characteristics of the device with dielectricdoi:10.1063/1.4816440 fatcat:76clyn3mw5hcfkheqy6evduu2e
more »... ing at different locations across its surface are obtained experimentally. The results indicate that dielectric loading reduces the resonant frequency of the device, which is in good agreement with simulations. The shift in resonant frequency is employed as the sensor output for biomolecular experiments. The device is demonstrated as a resonant biomolecular sensor where the interactions between heparin and fibroblast growth factor 2 are probed. The sensitivity of the device is obtained as 3.7 MHz/(lg/ml) with respect to changes in concentration of heparin. V C 2014 AIP Publishing LLC.
doi:10.4174/jkss.2011.80.suppl1.s21 pmid:22066077 pmcid:PMC3205373 fatcat:jrin3mspubgwxn53b6qps74rfe
Purpose: Ultrasound (US) elastography is a newly developed imaging technique for assessing tissue stiffness by measuring the degree of the tissue's deformation in response to the application of an external force. This technique has recently been applied for making the diagnosis of nodular thyroid disease. The purpose of this study was to evaluate the diagnostic utility of US elastography for differentiating benign thyroid nodules from malignant thyroid nodules. Methods: A total of 63doi:10.16956/kjes.2011.11.1.12 fatcat:sf7hrix3dnbq3jqcc5chwjgui4
more »... patients with thyroid nodules and who were referred for surgical treatment were examined in this study. Seventy-five nodules in these patients were examined by US B-mode, color Doppler US and US elastography. The final diagnosis was obtained from the histologic findings. The tissue stiffness on ultrasound elastography was scored from 1 (elasticity in the whole nodule) to 5 (no elasticity in the nodule and in the posterior shadowing). Results: On US elastography, 18 of 32 benign nodules (56.3%) had a score of 1 to 3, whereas 23 of 43 malignant nodules (62.8%) had a score of 4 to 5. With applying a US elastography score of 4-5 as an indicator for malignancy, the sensitivity, specificity, positive predictive value and negative predictive value of US elastography were 65.9%, 52.9%, 62.8% and 56.3%, respectively. Of the 14 follicular tumors, 12 were follicular adenoma and four were follicular carcinoma. The sensitivity and specificity of US elastography for diagnosing follicular carcinoma were 50.0% and 81% (56=69), respectively. The positive and negative predictive values were 55.2% (16=29) and 60.0%, respectively. The accuracy of the technique was 57.1%. The findings of US elastography were not significantly correlated with the histopathologic findings. Conclusion: This study has shown that US elastography may be not useful for differentiating between benign and malignant thyroid nodules. Further studies are needed to confirm the usefulness of US elastography for making the differential diagnosis of thyroid nodules. (Korean J Endocrine Surg 2011;11:12-17)
In this paper, we will consider the Hyers-Ulam stability for the second order inhomogeneous linear differential equation, u ′ ′ ( x ) + α u ′ ( x ) + β u ( x ) = r ( x ) , with constant coefficients. More precisely, we study the properties of the approximate solutions of the above differential equation in the class of twice continuously differentiable functions with suitable conditions and compare them with the solutions of the homogeneous differential equation u ′ ′ ( x ) + α u ′ ( x ) + β u (doi:10.3390/math7090806 fatcat:in3v7avuqracbnl4lkina7esxa
more »... x ) = 0 . Several mathematicians have studied the approximate solutions of such differential equation and they obtained good results. In this paper, we use the classical integral method, via the Wronskian, to establish the stability of the second order inhomogeneous linear differential equation with constant coefficients and we will compare our result with previous ones. Specially, for any desired point c ∈ R we can have a good approximate solution near c with very small error estimation.
We will prove the generalized Hyers–Ulam stability of isometries, with a focus on the stability for restricted domains. More precisely, we prove the generalized Hyers–Ulam stability of the orthogonality equation and we use this result to prove the stability of the equations ∥f(x)−f(y)∥=∥x−y∥ and ∥f(x)−f(y)∥2=∥x−y∥2 on the restricted domains. As we can easily see, these functional equations are symmetric in the sense that they become the same equations even if the roles of variables x and y are exchanged.doi:10.3390/sym13020282 fatcat:l42252prdfaz3az3lp37mwdpl4
Although natural orifice extraction is now widely performed, there have been no reports of this procedure following subtotal gastrectomy for gastric cancer. This report describes trans-vaginal specimen extraction in four patients with early gastric cancer. Methods The clinical data of four patients with early gastric cancer were reviewed. Totally laparoscopic subtotal gastrectomy and D1 ? b lymph node dissection was performed using five trocars and a conventional procedure. Posterior colpotomydoi:10.1007/s10120-011-0006-8 pmid:21264485 fatcat:wjxubv2vujbnvnfcrmqgapkfwm
more »... as performed by an experienced gynecologist, who retrieved the specimens in a retrieval bag via the trans-vaginal route. The colpotomy site was repaired immediately following specimen removal. Reconstruction was performed using the intracorporeal Billroth II method and an endo-GIA 60. Results Totally laparoscopic subtotal gastrectomy and trans-vaginal specimen extraction was successfully accomplished in all patients without intraoperative complications. Conclusions The present technique may be a safe and feasible operative procedure for some limited groups of elderly female patients with early gastric cancer.
하지만, 최근에 근위부 위 절제술 후 복원 방법을 달리 했을 때, 역류 식도염 및 문합부 협착 등을 개선하고 삶의 질을 향상시킬 수 있다는 보고가 나오 고 있다.(15,20) Jung 등(21)은 근위부 위 절제술 및 잔류 위 전정부를 이용한 이중 통로법을 시행하여 역류 식도염의 정도를 낮추었다고 보고하였고, Sakuramoto 등(22)은 근위 부 위 절제술 ...doi:10.4174/jkss.2010.79.4.246 fatcat:fofyzfe3dzdrppcakr4qlnksfa
Objective: Meconium peritonitis (MP) is defined as sterile chemical peritonitis, resulting from intrauterine bowel perforation. MP is rare but has high morbidity and mortality in neonates. We aimed to review the treatment and clinical course of MP, and to find out the possible relationship between perinatal parameters and outcomes. Methods: All patients diagnosed with MP between February 2006 and October 2016 were inves tigated retrospectively. MP was diagnosed with prenatal ultrasonography anddoi:10.14734/pn.2017.28.2.29 fatcat:rilu6j2ltfctfpix22wff7nkjq
more »... the types of MP were identified intraoperatively. Findings of prenatal ultrasonography, gestational age, gender, birth weight, delivery type, APGAR score, clinical symptoms, causes of MP, mortality and morbidity, and hospital stay were analysed. Results: Thirteen patients were antenatally diagnosed with MP. Median gestational age was 37 weeks. All patients were diagnosed using prenatal ultrasonography. Calcification was found in 13 patients, bowel dilatation in 8, fetal ascites in 7, polyhydramnios in 6, and pseudocyst in 3. Five were females and 8 were males. Median birth weight was 2,930 g. Symptoms of abdominal dis tension were reported in 10 patients, bilious vomiting in 2, pneumoperitoneum in 2, and no symp toms and signs of MP in 1. One patient recovered with conservative management and the other 12 patients required surgery. All patients who underwent surgery had underlying patholo gic causes; jejunoileal atresia, ileal perforation and transverse colonic perforation. Two cases of mortality oc curred. Conclusion: The mortality patients were haemodynamically unstable and had received preope rative pressor agents and ventilator care. More studies are needed to investigate the correlation between mortality and preoperative vital status.
One of the most important factors in training object recognition networks using convolutional neural networks (CNNs) is the provision of annotated data accompanying human judgment. Particularly, in object detection or semantic segmentation, the annotation process requires considerable human effort. In this paper, we propose a semi-supervised learning (SSL)-based training methodology for object detection, which makes use of automatic labeling of un-annotated data by applying a network previouslyarXiv:1802.06964v1 fatcat:6xslsr25wjcgbdj4l65wpow3ga
more »... trained from an annotated dataset. Because an inferred label by the trained network is dependent on the learned parameters, it is often meaningless for re-training the network. To transfer a valuable inferred label to the unlabeled data, we propose a re-alignment method based on co-occurrence matrix analysis that takes into account one-hot-vector encoding of the estimated label and the correlation between the objects in the image. We used an MS-COCO detection dataset to verify the performance of the proposed SSL method and deformable neural networks (D-ConvNets) as an object detector for basic training. The performance of the existing state-of-the-art detectors (DConvNets, YOLO v2, and single shot multi-box detector (SSD)) can be improved by the proposed SSL method without using the additional model parameter or modifying the network architecture.
Phosphate overload contributes to mineral bone disorders that are associated with crystal nephropathies. Phytate, the major form of phosphorus in plant seeds, is known as an indigestible and of negligible nutritional value in humans. However, the mechanism and adverse effects of high-phytate intake on Ca2+ and phosphate absorption and homeostasis are unknown. Here, we show that excessive intake of phytate along with a low-Ca2+ diet fed to rats contributed to the development of crystaldoi:10.7554/elife.52709 pmid:32271147 fatcat:6pucrj7lmvchbklu4jzkwad6wu
more »... ies, renal phosphate wasting, and bone loss through tubular dysfunction secondary to dysregulation of intestinal calcium and phosphate absorption. Moreover, Ca2+ supplementation alleviated the detrimental effects of excess dietary phytate on bone and kidney through excretion of undigested Ca2+-phytate, which prevented a vicious cycle of intestinal phosphate overload and renal phosphate wasting while improving intestinal Ca2+ bioavailability. Thus, we demonstrate that phytate is digestible without a high-Ca2+ diet and is a risk factor for phosphate overloading and for the development of crystal nephropathies and bone disease.
Ke y W o rd s : Int e s t ina l; Ly m p ho m a ; T -ly m p ho cy t e s ; Gas t ro int e s t ina l sy s t e m ; M a la b s o rpt io n s y n d ro m e s Address reprint requests to : My ung-Ju Ahn, M.D.,doi:10.3904/kjim.2000.15.3.245 pmid:11242815 pmcid:PMC4531775 fatcat:ojlt7xaok5gy5bfuzw7rj27eae
Choi, Y.J.; Moon, K.M.; Chung, K.W.; Jeong, J.W.; Park, D.; Kim, D.H.; Yu, B.P.; Chung, H.Y. ...doi:10.3390/ijms20092126 fatcat:z5rsjcqvfzbfpf7fwcfeos64zm
Purpose: With the advancement of laparoscopic instruments and accumulation of surgical technique, laparoscopic liver resection is currently performed for various benign and malignant liver diseases. However, controversies still remain over laparoscopic liver resection for malignant liver diseases including HCC and its oncologic safety is yet to be established. This study aims at determining the safety, feasibility and short-term oncologic outcomes of laparoscopic liver resection performed fordoi:10.4174/jkss.2011.80.1.51 fatcat:ez5zbqvrufb6tcf2rdyvnwkezy
more »... C. Methods: From July 2008 to March 2010, laparoscopic liver resection was performed at our hospital on a total of 45 patients with various benign and malignant liver diseases. Among these 45 patients, 16 patients diagnosed with HCC were reviewed retrospectively. Results: The mean age of the patients was 59.25, comprising 11 male patients (68.8%) and 5 female patients (31.2%). The location of tumor was left lateral in 7 cases, 4 cases in segment 6, 2 cases in segment 7, 2 cases in segment 5, 1 case in segment 4 and 1 case in caudate lobe. Wedge resection was performed in 11 cases, left hemi hepatectomy in 2 cases, left lateral sectionectomy in 2 cases, caudate lobectomy in 1 case. The mean operative time was 248.75 minutes. The mean hospital stay was 13.8 days, and there were no post-operative recurrences during the post-operative follow-up period. Conclusion: When performed by expert surgeons in selected patients, laparoscopic liver resection for HCC is a feasible and safe procedure. (J Korean Surg Soc 2011;80:51-55)
Choi. ...doi:10.1111/j.1574-6968.1998.tb13016.x pmid:9627968 fatcat:zo4ph62vjjfhvkc446msfvftue
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