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Information Extraction from Retinal Images with Agent-Based Technology

Pablo Chamoso, Sara Rodríguez, Luis García-Ortiz, Juan Corchado
2018 Processes  
The study of retinal vessels can provide information on a wide range of illnesses in the human body.  ...  Numerous works have already focused on this new field of research and several medical software programs have been proposed to facilitate the close examination of retinal vessels.  ...  In addition to the previously mentioned tools, there are others; the Singapore I Vessel Assessment (SIVA) software tool [11] which allows for semi-supervised measurement of many retinal vessel parameters  ... 
doi:10.3390/pr6120254 fatcat:mwap3lt7bbfd5deyyi35wogody

The long-term effects of anti-vascular endothelial growth factor therapy on the optical coherence tomography angiographic appearance of neovascularization in age-related macular degeneration

Emily S. Levine, Eugenia Custo Greig, Luísa S. M. Mendonça, Shilpa Gulati, Ivana N. Despotovic, A. Yasin Alibhai, Eric Moult, Nora Muakkassa, Maddalena Quaranta-El Maftouhi, Adil El Maftouhi, Usha Chakravarthy, James G. Fujimoto (+5 others)
2020 International Journal of Retina and Vitreous  
In nAMD, complete regression of an MNV network exposed to anti-VEGF is rare. This work emphasizes the role of anti-VEGF as anti-leakage rather than vascular regression agents in nAMD.  ...  Images were graded for MNV type, area, activity, mature versus immature vessels, vessel density, presence of atrophy, atrophy location and area.  ...  Due to the lack of agreement among graders in this study, we were unable to draw conclusions from the classification of vessels as mature or immature.  ... 
doi:10.1186/s40942-020-00242-z pmid:32844038 pmcid:PMC7441632 fatcat:fgpkwl57t5defgd4ocilgnwhee

Comparison of the 1-year Outcomes of Conbercept Therapy between Two Different Angiographic Subtypes of Polypoidal Choroidal Vasculopathy

Xiao-Xin Li, Yong Cheng, Xuan Shi, Jin-Feng Qu, Ming-Wei Zhao
2016 Chinese Medical Journal  
CRT was defined as the mean retinal thickness within the 1 mm diameter circle centered at fovea. CRT was also obtained from the computational software output.  ...  [29, 30, 32] In the first type, both feeder and draining vessels are visible on ICGA, and network vessels are numerous.  ... 
doi:10.4103/0366-6999.192779 pmid:27779169 pmcid:PMC5125341 fatcat:3c2mnqvawrekzoo76n5lc4xynm

Qualitative and Quantitative Assessment of Vascular Changes in Diabetic Macular Edema after Dexamethasone Implant Using Optical Coherence Tomography Angiography

Lisa Toto, Rossella D'Aloisio, Marta Di Nicola, Giuseppe Di Martino, Silvio Di Staso, Marco Ciancaglini, Daniele Tognetto, Leonardo Mastropasqua
2017 International Journal of Molecular Sciences  
The aim of this study was to investigate retinal and choriocapillaris vessel changes in diabetic macular edema (DME) after the intravitreal dexamethasone implant (IDI) using optical coherence tomography  ...  Best corrected visual acuity (BCVA), retinal sensitivity, and central retinal thickness (CMT) were also evaluated in both groups of patients.  ...  Acknowledgments: This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.  ... 
doi:10.3390/ijms18061181 pmid:28574436 pmcid:PMC5486004 fatcat:afbho45byzbsths2rwfbr335qi

Artificial Intelligence for Automated Overlay of Fundus Camera and Scanning Laser Ophthalmoscope Images

Melina Cavichini, Cheolhong An, Dirk-Uwe G. Bartsch, Mahima Jhingan, Manuel J. Amador-Patarroyo, Christopher P. Long, Junkang Zhang, Yiqian Wang, Alison X. Chan, Samantha Madala, Truong Nguyen, William R. Freeman
2020 Translational Vision Science & Technology  
This technique permitted vessel alignment determination by human observers and 5 masked graders evaluated alignment by the AI and conventional warping in 25 fields for each image.  ...  Software displayed image pairs as a 5 × 5 checkerboard grid composed of alternating subimages.  ...  The funding organizations had no role in the design or conduct of this research.  ... 
doi:10.1167/tvst.9.2.56 pmid:33173612 pmcid:PMC7594596 fatcat:umbdlat2ebfvrjv5qwz7hxwrxi

Detection of Neovascularization in Diabetic Retinopathy

Siti Syafinah Ahmad Hassan, David B. L. Bong, Mallika Premsenthil
2011 Journal of digital imaging  
It is neovascularization where new blood vessels grow due to extensive lack of oxygen in the retinal capillaries.  ...  A function matrix box was added in order to classify the neovascularization from natural blood vessel. A region-based neovascularization classification was attempted as a diagnostic accuracy.  ...  The authors would like to thank to local general hospital and all the public available databases (DRIVE, STARE, Diaretdb0, and Messidor program) for providing the diabetic retinal images and clinical information  ... 
doi:10.1007/s10278-011-9418-6 pmid:21901535 pmcid:PMC3348992 fatcat:u43r3zpnwvgylbu3xyrsbnzotm

Advances in Retinal Optical Imaging

Yanxiu Li, Xiaobo Xia, Yannis Paulus
2018 Photonics  
Significant improvements have occurred both in hardware such as lasers and optics in addition to software image analysis.  ...  Retinal imaging has undergone a revolution in the past 50 years to allow for better understanding of the eye in health and disease.  ...  Figure 2 . 2 PAM imaging of retinal blood vessels in rabbits.  ... 
doi:10.3390/photonics5020009 pmid:31321222 pmcid:PMC6639094 fatcat:dzd5e4l32verberxtihabe4e74

Automated segmentation and fractal analysis of high-resolution non-invasive capillary perfusion maps of the human retina

Hong Jiang, Delia Cabrera DeBuc, Tatjana Rundek, Byron L. Lam, Clinton B. Wright, Meixiao Shen, Aizhu Tao, Jianhua Wang
2013 Microvascular Research  
Pathological retinal microvascular changes may reflect microangiopathic processes in the brain.  ...  Recent advances in optical imaging techniques have enabled imaging of the retinal microvasculature at the capillary level, and the generation of high-resolution, non-invasive capillary perfusion maps (  ...  Acknowledgments Grant/financial support: Supported in part by the research grants NIH R01EY020607, NIH R01EY020607S, NIH Center Grant P30 EY014801 and the grant from Research to Prevent Blindness (RPB)  ... 
doi:10.1016/j.mvr.2013.06.008 pmid:23806780 pmcid:PMC3773708 fatcat:wdl2cbhosbcankhxaozo3cluou

Relationships among Ocular Blood Flow Shown by Laser Speckle Flowgraphy, Retinal Arteriosclerotic Change, and Chorioretinal Circulation Time Obtained by Fluorescein Angiography

Hironori Osamura, Tomoaki Shiba, Takashi Itokawa, Tadashi Matsumoto, Yuichi Hori
2017 Journal of Ophthalmology  
The MBR values throughout the ONH (MBR-A), in the tissue (MBR-T), and in the vessels (MBR-V) were analyzed. Results.  ...  The severity of retinal arteriosclerosis was classified according to the Scheie classification.  ...  After we had identified the margin of the ONH by hand using a round band (Figure 1 (a)), the software separated out the vessels using the automated definitive threshold (Figure 1 (b)) and then analyzed  ... 
doi:10.1155/2017/2969064 pmid:28331635 pmcid:PMC5346362 fatcat:jela6bm34ffh5ggx6akn75odna

Novel Method for Automated Analysis of Retinal Images: Results in Subjects with Hypertensive Retinopathy and CADASIL

Michele Cavallari, Claudio Stamile, Renato Umeton, Francesco Calimeri, Francesco Orzi
2015 BioMed Research International  
The results showed that our approach is effective in detecting and quantifying the retinal vessel abnormalities.  ...  The method was implemented in two conditions known for being associated with retinal vessel changes: hypertensive retinopathy and Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and  ...  Discussion We developed two custom-made plugins and embedded them into the free software Image-J in order to provide a novel method for quantitative, semiautomated analysis of retinal vessel features in  ... 
doi:10.1155/2015/752957 pmid:26167496 pmcid:PMC4475739 fatcat:x4mkxw4zhbcvlpw64gswjmnwbm

Recent Development on Detection Methods for the Diagnosis of Diabetic Retinopathy

Imran Qureshi, Jun Ma, Qaisar Abbas
2019 Symmetry  
Manual inspection of morphological changes in retinal anatomic parts are tedious and challenging tasks.  ...  DR occurs due to a high ratio of glucose in the blood, which causes alterations in the retinal microvasculature. Without preemptive symptoms of DR, it leads to complete vision loss.  ...  Acknowledgments: This work is supported by the National Natural Science Foundation of China (NNSFC) under the grant no: (61672322, 61672324) and is part of a PhD research project conducted in the intelligent  ... 
doi:10.3390/sym11060749 fatcat:7wm46cxjtrbwnbxev5ulykjvmy

Intraretinal Cysts as a Manifestation of Retinal Angiomatous Proliferation in Optical Coherence Tomography Angiography

Jakub J. Kałużny, Przemysław Zabel, Beata Danek, Damian Jaworski, Jarosław Makowski
2022 Medicina  
Conclusions: The presence of intraretinal cysts on SDOCT retinal sections in eyes with neovascular AMD corresponds to the presence of IRN on OCTA examination.  ...  The aim of the study was to determine if the presence of intraretinal cysts is positively correlated with diagnosis of retinal angiomatous proliferation (RAP) in optical coherence tomography angiography  ...  In addition, RPE hyperplasia and connections between retinal vessels begin to appear.  ... 
doi:10.3390/medicina58050676 pmid:35630094 pmcid:PMC9145726 fatcat:gf62bqlvtnfwtiwgr5jdedqa5e

Retinal Vessel Analysis (RVA) in the Context of Subarachnoid Hemorrhage - A Proof of Concept Study

Walid Albanna, Catharina Conzen, Miriam Weiss, Hans Clusmann, Matthias Fuest, Marguerite Mueller, Marc Alexander Brockmann, Walthard Vilser, Arno Schmidt-Trucksäss, Anke Hoellig, Marcel Seiz, Claudius Thomé (+3 others)
2016 PLoS ONE  
This investigation aims to determine the feasibility of standardized retinal vessel analysis (RVA) in the context of SAH.  ...  Data was acquired using a manoeuvrable Dynamic Vessel Analyzer (Imedos Systems UG, Jena) for examination of retinal vessel dimension and neurovascular coupling.  ...  Acknowledgments Particularly in view of the constructional setup of the imaging device, we would like to express our gratitude for the invaluable practical support that was generously provided by Mrs Jasmin  ... 
doi:10.1371/journal.pone.0158781 pmid:27388619 pmcid:PMC4936715 fatcat:c2slobojwjcwtdzu23q65z4gjm

Interactive retinal blood flow analysis of the macular region

Jing Tian, Gábor Márk Somfai, Thalmon R. Campagnoli, William E. Smiddy, Delia Cabrera Debuc
2016 Microvascular Research  
However, the measurements of BFV using a user-guided vessel segmentation tool may induce significant inter-observer differences and BFR is not provided in the built-in software.  ...  The intraclass correlation (ICC) of BFV between our proposed method and built-in software were 0.924 and 0.830 for vessels from healthy and NPDR subjects, respectively.  ...  Acknowledgement This study was supported in part by a NIH Grant No. NIH R01EY020607, a NIH Center Grant No.  ... 
doi:10.1016/j.mvr.2015.11.003 pmid:26569349 pmcid:PMC4706801 fatcat:wqz43iyizfh2lfc624p5gfiw5m

ALTAIR: Supervised Methodology to Obtain Retinal Vessels Caliber

Pablo CHAMOSO, Henar PÉREZ-RAMOS, Ángel GARCÍA-GARCÍA
2014 Advances in Distributed Computing and Artificial Intelligence Journal  
Image analysis; Fundus images; Vessels caliber A back of the eye examination allows performing a noninvasive evaluation of the retinal microcirculation, as well as of the vascular damage induced by multiple  ...  Its development will subsequently allow analyzing its utility in various clinical environments.  ...  ., 2004) , are: diabetic retinopathy, macular degeneration, retinal detachment, retinitis pigmentosa, blood vessel disorders, arteriosclerotic retinopathy, hypertensive retinopathy, retinal vein obstruction  ... 
doi:10.14201/adcaij2014345060 fatcat:cgh7idrp3zg6dkbo427yvbxxla
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