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Stimulator Design of Retinal Prosthesis

Jun OHTA, Toshihiko NODA, Kenzo SHODO, Yasuo TERASAWA, Makito HARUTA, Kiyotaka SASAGAWA, Takashi TOKUDA
2017 IEICE transactions on electronics  
This study focuses on the design of electrical stimulator for retinal prosthesis.  ...  The concept of a smart electrode, in which a microchip is embedded inside an electrode, is presented for future retinal prostheses with over 1000 electrodes.  ...  Kanda of Osaka University of Medical School for their continuous supports.  ... 
doi:10.1587/transele.e100.c.523 fatcat:vq3bpiu275d3rel7d7wc2wfb4y

Performance improvement and in vivo demonstration of a sophisticated retinal stimulator using smart electrodes with built-in CMOS microchips

Toshihiko Noda, Yukari Nakano, Yasuo Terasawa, Makito Haruta, Kiyotaka Sasagawa, Takashi Tokuda, Jun Ohta
2018 Japanese Journal of Applied Physics  
A retinal stimulator for next-generation retinal prosthesis was fabricated and demonstrated through in vivo experiments.  ...  The assembly process of smart electrodes with built-in microchips was also optimized.  ...  Acknowledgments This work was partially supported by a Grant-in-Aid for Scientific Research (C), No. 18K04265, from the Japan Society for the Promotion of Science (JSPS) and a research grant from Murata  ... 
doi:10.7567/jjap.57.1002b3 fatcat:dat44ledbrdytkax6tvu3u6fey

CMOS Imaging Devices for Biomedical Applications

Jun OHTA, Takuma KOBAYASHI, Toshihiko NODA, Kiyotaka SASAGAWA, Takashi TOKUDA
2011 IEICE transactions on communications  
The topics include dish type image sensors, deep-brain implantation devices for small animals, and retinal prosthesis devices.  ...  Fundamental device structures and their characteristics are described, and the results of in vivo experiments are presented. key words: CMOS image sensors, biomedical applications, retinal prosthesis,  ...  Ltd. for their valuable discussions and conducting animal experiments involving retinal prosthesis, and Profs. S. Shiosaka and H.  ... 
doi:10.1587/transcom.e94.b.2454 fatcat:3lfqyqtcyzfk5f4ueqrbuw2yla

Functional Validation of Intelligent Retinal Stimulator Using Microchip-embedded Smart Electrode

Toshihiko Noda, Makito Haruta, Kiyotaka Sasagawa, Takashi Tokuda, Jun Ohta
2018 Sensors and materials  
A smart electrode that has a built-in CMOS microchip was fabricated for use as a retinal stimulator used in retinal prostheses.  ...  Based on this ex vivo experiment, the fabricated electrode showed optimal performance for retinal stimulation.  ...  ., Japan, for technical discussions.  ... 
doi:10.18494/sam.2018.1649 fatcat:37za2utjwrasjd6wlbfpk23rie

Current Modalities for Low Vision Rehabilitation

Richa Agarwal, Alka Tripathi
2021 Cureus  
Visual rehabilitation is an effective method for increasing the quality of life among individuals with low vision or blindness due to untreatable causes.  ...  Low vision rehabilitation aims for patients to use their residual vision effectively and efficiently to enable them to live independent and productive lives.  ...  FIGURE 3 : 3 Smart cane Smart cane [24] (Graphic courtesy: Amit Bandre) TABLE 1 : 1 Studies using MSCs for retinal degenerative diseases.  ... 
doi:10.7759/cureus.16561 pmid:34466307 pmcid:PMC8396411 fatcat:mneemjp6izaufb7nimj3b5jtnm

Vision Restoration and Vision Chip Technologies

Akos Kusnyerik, Kristof Karacs, Akos Zarandy
2011 Procedia Computer Science  
Also, the vertically integrated vision chip technology is bringing a revolution in the design of artificial vision systems.  ...  The future smart 3D image sensor architectures will most probably consist of a sensor layer at the top and various processing layers below.  ...  Although the epiretinal prosthesis offer lower resolution, but requires shorter surgery for implantation.  ... 
doi:10.1016/j.procs.2011.12.036 fatcat:myplqv35ujfplkp6l5dnjwt6bm

Implantable CMOS Biomedical Devices

Jun Ohta, Takashi Tokuda, Kiyotaka Sasagawa, Toshihiko Noda
2009 Sensors  
Topics include retinal prosthesis devices and deep-brain implantation devices for small animals. Fundamental device structures and characteristics as well as in vivo experiments are presented.  ...  Acknowledgements The research related to retinal prostheses was supported in part by the Strategic Research Program for Brain Sciences, MEXT, Japan, by the Asahi Glass Foundation, and by a Health and Labour  ...  The research related to in vivo CMOS image sensing devices was supported in part by the Semiconductor Technology Academic Research Center (STARC), and by the Japan Science and Technology Agency (JST-CREST  ... 
doi:10.3390/s91109073 pmid:22291554 pmcid:PMC3260631 fatcat:eezqmssrozcmdorisuy2tfpkwy

Implantable CMOS biomedical devices

Jun Ohta
2012 2012 IEEE International Meeting for Future of Electron Devices, Kansai  
Topics include retinal prosthesis devices and deep-brain implantation devices for small animals. Fundamental device structures and characteristics as well as in vivo experiments are presented.  ...  Acknowledgements The research related to retinal prostheses was supported in part by the Strategic Research Program for Brain Sciences, MEXT, Japan, by the Asahi Glass Foundation, and by a Health and Labour  ...  The research related to in vivo CMOS image sensing devices was supported in part by the Semiconductor Technology Academic Research Center (STARC), and by the Japan Science and Technology Agency (JST-CREST  ... 
doi:10.1109/imfedk.2012.6218567 fatcat:rfs5lpbz35cxxaqfuwfir4ex7e

Artificial Retina IC [chapter]

Jun Ohta
2010 Bio-Medical CMOS ICs  
Fig. 4 4 Three types of retinal prosthesis. Fig. 6 6 Illustraion of STS-based retinal prosthesis system. Cortesy of Nidek Co. Inc. Fig. 7 7 A mock-up system of STS-based retinal prosthesis.  ...  The system of epi-retinal implanation can be used an artificial cochlear system except for the sitmulator.  ... 
doi:10.1007/978-1-4419-6597-4_14 dblp:series/icas/Ohta11 fatcat:37vrjmy3izgs5mkmehqdbjanvi

A visual prosthesis with 100 electrodes featuring wireless signals and wireless power transmission

Yasuo Terasawa, Akihiro Uehara, Eiji Yonezawa, Tohru Saitoh, Kenzo Shodo, Motoki Ozawa, Yasuo Tano, Jun Ohta
2008 IEICE Electronics Express  
A visual prosthesis is an artificial sensory organ that transmits visual information to a blind person by electrically stimulating residual neurons in the visual nervous system.  ...  We propose a visual prosthesis containing a multiplexer that is separately placed from the stimulator unit.  ...  Tano, "Silicon LSI-based smart stimulators for retinal prosthesis," IEEE Eng. Med. Biol. Mag.Terasawa, H. Tashiro, A. Uehara, T. Saitoh, M. Ozawa, T.  ... 
doi:10.1587/elex.5.574 fatcat:bls4kwx7hzdj7padzpxddeu5my

Guest Editorial: Sense and Sensibility in Neuroengineering

Fan-Gang Zeng, Silvestro Micera
2007 IEEE Transactions on Biomedical Engineering  
Asher and colleagues developed sophisticated image processing that can potentially track the implant position, as well as process and convert the optical image into patterned electric stimulation in real  ...  the visual image.  ... 
doi:10.1109/tbme.2007.894853 pmid:17554815 fatcat:kfvuyr7pmvfrhllmgay4qq3l5u

Development and Implantation of a Minimally Invasive Wireless Subretinal Neurostimulator

D.B. Shire, S.K. Kelly, Jinghua Chen, P. Doyle, M.D. Gingerich, S.F. Cogan, W.A. Drohan, O. Mendoza, L. Theogarajan, J.L. Wyatt, J.F. Rizzo
2009 IEEE Transactions on Biomedical Engineering  
A wirelessly operated, minimally invasive retinal prosthesis was developed for preclinical chronic implantation studies in Yucatan minipig models.  ...  Wireless operation of the retinal implant has been verified both in vitro and in vivo in three pigs for more than seven months, the latter by measuring stimulus artifacts on the eye surface using contact  ...  Since the optimal current level and stimulation protocols for providing restoration of usable visual percepts are not known, our design concept was to keep the 'smart' image processing hardware and/or  ... 
doi:10.1109/tbme.2009.2021401 pmid:19403357 pmcid:PMC7444418 fatcat:zfme3a5rwvezvkulhz6jkq6ira

New Era of Electroceuticals: Clinically Driven Smart Implantable Electronic Devices Moving towards Precision Therapy

RaviPrakash Magisetty, Sung-Min Park
2022 Micromachines  
and qualified smart electroceutical implant for targeted clinical use.  ...  Herein, the article discusses the smart implants' development challenges and opportunities, electromagnetic field effects, and their potential consequences, which will be useful for developing a reliable  ...  Although the above introduced retinal prosthesis systems and sub-systems, such as the bionic eye, retinal implants, and their electrode systems, etc., are authenticating with clinical experiment results  ... 
doi:10.3390/mi13020161 pmid:35208286 pmcid:PMC8876842 fatcat:2ctpuebpyvdkpmkvkeapxbhlje

Recent Progress in Wireless Sensors for Wearable Electronics

Young-Geun Park, Sangil Lee, Jang-Ung Park
2019 Sensors  
Also, state-of-the-art research related to the application of wearable sensor systems with wireless functionality is discussed, including electronic skin, smart contact lenses, neural interfaces, and retinal  ...  Current challenges and prospects of wireless sensor systems are discussed.  ...  Acknowledgments: The authors own many thanks to the anonymous reviewers for their instructive comments. Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/s19204353 pmid:31600870 pmcid:PMC6848938 fatcat:ogirk7mofndnzn4elqdqflgzfe

Fabrication of Fork-Shaped Retinal Stimulator Integrated with CMOS Microchips for Extension of Viewing Angle

2014 Sensors and materials  
A fork-shaped retinal stimulator for a wide viewing angle was fabricated and demonstrated. This stimulator has two flexible fork elements, each with a stimulus head.  ...  Retinal stimulation by the device evoked nerve responses from optic chiasma and produced a specific peak of evoked potential.  ...  It is also supported by a Grant-in-Aid for Young Scientists (B), #23760312, from the Japan Society for the Promotion of Science.  ... 
doi:10.18494/sam.2014.1029 fatcat:ipilkc3mffgk7jx2kfpnto46ky
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