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Magnetic Resonance Imaging technology — bridging the gap between noninvasive human imaging and optical microscopy

Jonathan R Polimeni, Lawrence L Wald
2018 Current Opinion in Neurobiology  
These new sampling strategies improve image acquisition efficiency and enable increased image encoding in the time-frame needed to follow hemodynamic changes associated with brain activation.  ...  Technological advances in Magnetic Resonance Imaging (MRI) have provided substantial gains in the sensitivity and specificity of functional neuroimaging.  ...  Bastien Guérin, Kawin Setsompop, and Thomas Witzel for helpful comments, and Dr. Berkin Bilgic for help with the wave-CAIPI sampling simulation.  ... 
doi:10.1016/j.conb.2018.04.026 pmid:29753942 pmcid:PMC6015259 fatcat:7msf5i7k5ja3tpavexhuzlw7wu

The power of using functional fMRI on small rodents to study brain pharmacology and disease

Elisabeth Jonckers, Disha Shah, Julie Hamaide, Marleen Verhoye, Annemie Van der Linden
2015 Frontiers in Pharmacology  
Functional magnetic resonance imaging (fMRI) is an excellent tool to study the effect of pharmacological modulations on brain function in a non-invasive and longitudinal manner.  ...  In addition, fMRI techniques allow one to dissect how specific modifications (e.g., treatment, lesion etc.) modulate the functioning of specific brain areas (st-fMRI, phMRI) and how functional connectivity  ...  ACKNOWLEDGMENTS The authors acknowledge the Institute for the Promotion of Innovation by Science and Technology (IWT) in Flanders grant agreement 131060, Molecular Imaging of Brain Pathophysiology  ... 
doi:10.3389/fphar.2015.00231 pmid:26539115 pmcid:PMC4612660 fatcat:vxu45hrsn5hchn46yitjtt76my

Characterizing Rapid Fluctuations of Resting State Functional Connectivity in Demyelinating, Neurodegenerative, and Psychiatric Conditions: From Static to Time-Varying Analysis

Paola Valsasina, Milagros Hidalgo de la Cruz, Massimo Filippi, Maria A. Rocca
2019 Frontiers in Neuroscience  
Functional magnetic resonance imaging (fMRI) at resting state (RS) has been widely used to characterize the main brain networks.  ...  Aim of this review is to provide a description of the methods currently used to assess TVC on RS fMRI data, and to summarize the main results of studies applying TVC in healthy controls and patients with  ...  Functional magnetic resonance imaging (fMRI) at resting state (RS) has been widely used to characterize the main brain networks.  ... 
doi:10.3389/fnins.2019.00618 pmid:31354402 pmcid:PMC6636554 fatcat:lezpk4273ne6jma6z45k6bsvii

Multimodal fusion of structural and functional brain imaging in depression using linked independent component analysis

Luigi A. Maglanoc, Tobias Kaufmann, Rune Jonassen, Eva Hilland, Dani Beck, Nils Inge Landrø, Lars T. Westlye
2019 Human Brain Mapping  
Machine learning revealed low model performance for classifying patients from controls and predicting symptom loads for depression and anxiety, but high age prediction accuracy.  ...  Precise clinical stratification and methods for brain phenotyping at the individual level based on large training samples may be needed to parse the neuroanatomy of depression.  ...  The permutation testing was performed using resources provided by UNINETT Sigma2 -the National Infrastructure for High Performance Computing and Data Storage in Norway. All rights reserved.  ... 
doi:10.1002/hbm.24802 pmid:31571370 fatcat:g7y765irerdihhx4mx64nehug4

Monitoring reperfused myocardial infarction with delayed left ventricular systolic dysfunction in rabbits by longitudinal imaging

Yuanbo Feng, Bianca Hemmeryckx, Liesbeth Frederix, Marleen Lox, Jun Wu, Ward Heggermont, Hua Rong Lu, David Gallacher, Raymond Oyen, H Roger Lijnen, Yicheng Ni
2018 Quantitative Imaging in Medicine and Surgery  
Cardiac magnetic resonance imaging (cMRI), transthoracic echocardiography (echo), and blood samples were collected at baseline, in acute (48 hours or 1 week) and chronic (7 weeks) stage subsequent to MI  ...  This experimental LVSD platform in rabbits may interest researchers in the field of experimental cardiology and help strengthen drug development and translational research for the management of cardiovascular  ...  Letter to the Editor Incidental abnormal bone marrow signal on magnetic resonance imaging and reflexive testing for the JAK2 V617F mutation  ... 
doi:10.21037/qims.2018.09.05 pmid:30306056 pmcid:PMC6177364 fatcat:cqroeb5ch5enlh76obrg4rlyea

Poster Session I

2013 Neuropsychopharmacology  
After acquisition and baseline performance was established at each of the 3 delay periods (5, 10, and 15 s), rats received a series of drug challenges.  ...  This may prove as a useful avenue to reducing CVD risk. Those with the MTHFR T or COMT Met alleles may not benefit from folate, but this needs further follow up.  ...  Abi-Dargham, and S. Kapur, Arch Gen Psychiatry 69, 776 (2012). 2  ... 
doi:10.1038/npp.2013.279 fatcat:54ipecxjarcvljrvn5fgtgif5u

39th European Conference on Visual Perception (ECVP) 2016 Barcelona

2016 Perception  
Using ultra-high-field (7 T) fMRI and neural model-based population-receptive field analyses, we describe numerosityselective neural populations organized into six widely separated topographic maps in  ...  Using ultra-high-field (7T) functional MRI and population receptive field modeling, we compare neural object size selectivity derived from responses to small (0.05-1.4 diameter) and large objects sizes  ...  inverted display orientation: Human ultra high field 9.4 T fMRI People prefer humanlike characteristics, looks and motion in toys, robots and avatars, as long as the likeness is not too compelling.  ... 
doi:10.1177/0301006616671273 fatcat:el2dmsuk6zd25pedijucuexl5m

ECR 2011 Book of Abstracts - A - Postgraduate Educational Programme

2011 Insights into Imaging  
New CT technology allows almost simultaneous image acquisition at two energies.  ...  For state-of-the-art MR liver and pancreatic imaging, a field strength of at least 1.5 T is required.  ...  It will review the differences between working in low-field and high-field, furthermore, it will provide an insight on the key differences of MRI safety when going from 1.5 T to 3 T scanner.  ... 
doi:10.1007/s13244-011-0078-3 pmid:23100070 pmcid:PMC3533621 fatcat:qa3ln4hhvve2hhumgwwnmykgoe

ECR 2015 Book of Abstracts - A - Postgraduate Educational Programme

2015 Insights into Imaging  
New CT technology allows almost simultaneous image acquisition at two energies.  ...  For state-of-the-art MR liver and pancreatic imaging, a field strength of at least 1.5 T is required.  ...  It will review the differences between working in low-field and high-field, furthermore, it will provide an insight on the key differences of MRI safety when going from 1.5 T to 3 T scanner.  ... 
doi:10.1007/s13244-015-0386-0 pmid:25708993 pmcid:PMC4349897 fatcat:m7eyvqcwojfpvf3lr5hy6dwjb4

ECR 2016 Book of Abstracts - A - Postgraduate Educational Programme

2016 Insights into Imaging  
New CT technology allows almost simultaneous image acquisition at two energies.  ...  For state-of-the-art MR liver and pancreatic imaging, a field strength of at least 1.5 T is required.  ...  It will review the differences between working in low-field and high-field, furthermore, it will provide an insight on the key differences of MRI safety when going from 1.5 T to 3 T scanner.  ... 
doi:10.1007/s13244-016-0474-9 pmid:26873353 pmcid:PMC4762839 fatcat:itxslbcacjhh3kixfkcwmdbt44

ECR 2013 Book of Abstracts - A - Postgraduate Educational Programme

2013 Insights into Imaging  
New CT technology allows almost simultaneous image acquisition at two energies.  ...  For state-of-the-art MR liver and pancreatic imaging, a field strength of at least 1.5 T is required.  ...  It will review the differences between working in low-field and high-field, furthermore, it will provide an insight on the key differences of MRI safety when going from 1.5 T to 3 T scanner.  ... 
doi:10.1007/s13244-013-0227-y pmid:23468009 pmcid:PMC3666656 fatcat:yitsk227mba2pl7wcypouf6tz4

49th Annual Congress of the Canadian Neurological Sciences Federation

2014 Canadian Journal of Neurological Sciences  
Methods: Twelve patients undergoing intracranial video-EEG monitoring underwent simultaneous iEEG-fMRI at 3T.  ...  Methods: Nine subjects undergoing intracranial video-EEG monitoring underwent simultaneous iEEG-fMRI at 3T. Epileptiform discharges that were isolated 3s prior, and 10s post-spike were identified.  ...  Conclusions: We have created a unique model of ONSD and we have determined the intra-operator reliability of ONSD measurement to be moderate to high, with no appreciable difference amongst multiple operators  ... 
doi:10.1017/s0317167100018709 fatcat:465gqktgybball5hywzsmeenqu

Single photon-emission computed tomography

Thomas A. Holly, Brian G. Abbott, Mouaz Al-Mallah, Dennis A. Calnon, Mylan C. Cohen, Frank P. DiFilippo, Edward P. Ficaro, Michael R. Freeman, Robert C. Hendel, Diwakar Jain, Scott M. Leonard, Kenneth J. Nichols (+2 others)
2010 Journal of Nuclear Cardiology  
Sentinel node biopsy (SNB) has been shown to be a safe, reliable and accurate alternative treatment modality for selected patients. Using this technique, lymphatic mapping is crucial.  ...  Adequate staging and treatment of the neck in squamous cell carcinoma of the oral cavity and oropharynx (OSCC) is of paramount importance.  ...  Conclusion Primary hyperparathyroidism is caused by a single parathyroid gland in up to 96% of cases.  ... 
doi:10.1007/s12350-010-9246-y pmid:20552312 fatcat:jrn7kubn45b3zjmtdwoln2pupa

Ion and Neutron Beams Discover New Facts from History

Anna Macková, Jan Kučera, Jan Kameník, Vladimír Havránek, Karel Kranda
2017 Nuclear Physics News  
With the advent of high field (i.e. 9.4 T) and the advanced shimming high-resolution proton spectra, studies of the mouse brain have been receiving great attention, especially for tumour response and fMRI  ...  The strength of the magnetic field may vary from 0.5 to 9.4 T according to the application and of course to the cost of the apparatus. An example of a 7 T system from Bruker is shown in Figure 5 .  ...  The treatment planning is finalised to increase the dose to the PTV (high TCP) keeping as low as possible the dose to the OARs (low NTCP). • TCP: Tumour control probability.  ... 
doi:10.1080/10619127.2017.1388686 fatcat:nxj4nqnfvfc4vbslelb67hauhe

Poster Session I

2010 Neuropsychopharmacology  
We have recently shown that sensitivity to cocaine-associated environments, a measure associated with drugseeking in rats, is relatively low during the juvenile period and increases during adolescence,  ...  We aimed to identify gene networks and pathways affected in homozygote IMPA1 and SMIT1 knockout mice and in Li-treated mice compared with wild-type (WT) untreated mice.  ...  Discussion: Depression is associated with increased susceptibility of T-cells to the HIV virus ex-vivo.  ... 
doi:10.1038/npp.2010.216 fatcat:v3q2xjxc45b2hckv33pzz7mtee
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