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We report the case of a 54-year-old woman with asthma and atopic dermatitis who presented a white spot on the genitalia. Histologic examination showed numerous eosinophils in the epithelium and the dermis. Eosinophilic esophagitis is defined as an esophageal disease characterized clinically by symptoms related to esophageal dysfunction and histologically by an eosinophil-predominant inflammation. We discuss the possible relationship between the two diseases.doi:10.1159/000511695 pmid:33708084 pmcid:PMC7923741 fatcat:o2uu43tgu5fu5al5jejl5j2noq
Mitsutoshi FUKUDA and Shiro NAGAOKA. Central Re search Laboratory, Toyo Soda Mfg. Co., Ltd. -136(40)- 応 用 物 理 第54巻 第2号(1985) Table1 ポ リス チ レン誘 導 体 の電 子 線 に対 す る感 度. ...doi:10.11470/oubutsu1932.54.135 fatcat:255phf4ktve5bmrx6ntpo5pzbe
Purpose: To examine the efficacy of valaciclovir (VACV) oral formulation as an alternative to topical treatments in a case of herpetic keratitis. Methods: The patient was a 61-year-old man who presented with dendritic keratitis in his left eye. After recognizing his difficulty in using eye ointment, we prescribed oral VACV 500 mg tablets twice daily for 7 days. We also describe our experiments with orally administered VACV in a mouse model of this disease. In this study, 143 Balb/c mice weredoi:10.1097/01.ico.0000247216.08886.9d pmid:17001196 fatcat:t5vdlxx5svc6jkgus5xfqb66pi
more »... culated with herpes simplex virus type 1 (HSV)-1 in each eye and treated with oral VACV 50 or 100 mg/kg twice daily, oral acyclovir (ACV) 50 mg/kg 5 times/d, 3% ACV eye ointment (ACV-O) 5 times/d, 3% ACV eye drops 5 times/d, or control for 5 days. Results: After 7 days, the patient's lesion was observed healed. Corrected left visual acuity was also improved, and HSV DNA was below detectable level. In the mouse study, slit-lamp examination on days 3, 4, 5, and 7 revealed that all 5 ACV and VACV treatment groups were significantly more effective in improving symptoms of herpetic epithelial keratitis versus control (P , 0.05). Moreover, VACV 100 mg/kg was superior to other treatments. Viral titers in mouse eyeball and trigeminal ganglia were lowest in the VACV 100 mg/kg group versus other treatment groups. Conclusion: Our case example suggests that when frequent application, blurred vision, and foreign body sensation after ACV-O application cause difficulty for patients to follow treatment, oral VACV might be an effective and safe option for patients with herpetic keratitis.
Isolated Cerebral Vascular Irrigatin A-Methodological Study SAKAE FUKUDA, ISAO 0CHI, SHIGEO TOYA, SHIRO SHIMIZU, MOTOHIRO TANAKA and MITHuo HATTORI The extremely profound hypothermia was investigated upon ... Isolated Cerebral Vascular Irrigatin A-Methodological Study SAKAE FUKUDA, ISAO 0CHI, SHIGEO TOYA, SHIRO SHIMIZU, MOTOHIRO TANAKA and MITHuo HATTORI ...doi:10.2176/nmc.5.101b fatcat:fjcqsjjwmrhwzlmwnuqjvhb2gm
Musashidai, Fuchu-shi, Tokyo 183-0042, Japan Anesthetic Management for Surgical Gastrostomy in a Patient with Leigh Syndrome Shiro FUKUDA, Nanae MIYAKE and Hiroaki MATAYOSHI SUMMARY underwent tracheostomy ...doi:10.2342/ymj.67.155 fatcat:ngvia2p2sffk7mmbs45h3abhxu
A B S T R A C T Background: Spinal epidural cavernous angioma was reported about 4% of all spinal epidural tumors, mostly generating as a primary lesion in the vertebral bone. Spinal epidural hematoma (SEDH) due to angioma without primary origin was very rare, which reported in the English literatures was only 10 cases including our case. The main symptoms were numbness and pains and motor weakness owing to the acute compression signs of cord and roots. Emergency surgical treatment was requireddoi:10.1016/j.inat.2017.11.007 fatcat:3cp32dejibdv5heasvotfcbw2e
more »... for the good surgical results. We present a rare case of cervical acute epidural hematoma due to ruptured venous angioma. Case presentation: A 78-year-old man, who suffered from sudden severe right suboccipitalgia., and sent to our hospital. He also noticed progressive numbness and motor weakness over his bilateral upper and lower extremities after the onset. Cervical CT and MRI showed acute intracanal hematoma over the right side of the cervical spine at C2 to C6. Emergency operation was performed 13 h after the onset. His sensory and motor symptoms were disappeared quickly after the operation. Pathological examination revealed spinal epidural hematoma due to venous angioma. Conclusion: This case presented with acute progressive deterioration of paresis and sensory disturbance, and required emergency operation. Early diagnosis and emergency surgical treatment are essential for the therapy of acute spinal epidural hematoma due to venous angioma.
鰓 原 嚢 胞 の4例 杉 山 忠 正 ・福 田 広 志 ・玉 井 達 人 河 内 四 郎 ・増 田 正 樹 ・大 谷 隆 俊 Four cases of branchial cyst Tadamasa SUGIYAMA•EHiroshi FUKUDA •E Tatsundo TAMAI Shiro KAWACHI •E Masaki MASUDA •E Takatoshi OHTANI 緒 言 鯛 ...doi:10.5794/jjoms.22.563 fatcat:cb326gtynbbmdlhdy47mnithea
The pericardial stitch, which is placed at the corner of the pericardial reflection on We appreciate the comments of Sasaguri and Fukuda. ...doi:10.1016/s0022-5223(99)70166-2 pmid:10419379 fatcat:fwr3k5pe2vbfhkpi26lofqadau
Fig. 1 (A) Left internal carotid angiogram, lateral view, showing a saccular aneurysm at the C 2 segment of the left internal carotid artery (ICA). (B) Three-dimensional digital subtraction angiogram showing the larger branch originating from the dome, and the smaller branch (arrow) originating from the ICA just distal to the aneurysm neck, which joined the larger branch to form the main trunk of the posterior communicating artery. Abstract A 62-year-old male presented with a rare case ofdoi:10.2176/nmc.50.568 pmid:20671382 fatcat:4sse3x5a5jd7dlm4nym5tai3xa
more »... ration of the supraclinoid segment of the internal carotid artery (ICA) at the origin of the posterior communicating artery (PCoA). The patient had a fusiform aneurysm at the proximal branch of the PCoA, which was successfully clipped, sparing the anterograde blood flow. The double origin and fenestration of the PCoA branching off at the C 2 segment of the left ICA suggested that this anomalous fenestration might have developed as the origin of the PCoA rather than the supraclinoid ICA during the early embryonal stage.
https://dx.doi.org/10. 5061/dryad.82557c0 Dryad Digital Repository, 10.5061/ dryad.82557c0 Decision Additional files Author(s) Year Dataset title Dataset URL Database and Identifier Kita S, Fukuda ...doi:10.7554/elife.48675 pmid:31647413 pmcid:PMC6822988 fatcat:g5sbsi66qfgm5owbwfy5n3rnli
Small RNA attracts increasing interest based on the discovery of RNA silencing and the rapid progress of our understanding of these phenomena. Although recent studies suggest the possible existence of yet undiscovered types of small RNAs in higher organisms, many studies to profile small RNA have focused on miRNA and/or siRNA rather than on the exploration of additional classes of RNAs. Results: Here, we explored human small RNAs by unbiased sequencing of RNAs with sizes of 19-40 nt. We providedoi:10.1186/1471-2164-9-157 pmid:18402656 pmcid:PMC2359750 fatcat:3cdgijy76jhv7a62iksyo44swy
more »... substantial evidences for the existence of independent classes of small RNAs. Our data shows that well-characterized non-coding RNA, such as tRNA, snoRNA, and snRNA are cleaved at sites specific to the class of ncRNA. In particular, tRNA cleavage is regulated depending on tRNA type and tissue expression. We also found small RNAs mapped to genomic regions that are transcribed in both directions by bidirectional promoters, indicating that the small RNAs are a product of dsRNA formation and their subsequent cleavage. Their partial similarity with ribosomal RNAs (rRNAs) suggests unrevealed functions of ribosomal DNA or interstitial rRNA. Further examination revealed six novel miRNAs. Conclusion: Our results underscore the complexity of the small RNA world and the biogenesis of small RNAs.
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