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Eosinophilic Vulvar Leukoderma

Kaya Nakada, Shiro Niiyama, Toshiaki Oharaseki, Hidetsugu Fukuda
2021 Case Reports in Dermatology  
We report the case of a 54-year-old woman with asthma and atopic dermatitis who presented a white spot on the genitalia. Histologic examination showed numerous eosinophils in the epithelium and the dermis. Eosinophilic esophagitis is defined as an esophageal disease characterized clinically by symptoms related to esophageal dysfunction and histologically by an eosinophil-predominant inflammation. We discuss the possible relationship between the two diseases.
doi:10.1159/000511695 pmid:33708084 pmcid:PMC7923741 fatcat:o2uu43tgu5fu5al5jejl5j2noq

Electron-Beam and X-Ray Resists

Mitsutoshi FUKUDA, Shiro NAGAOKA
1985 Oyobuturi  
Mitsutoshi FUKUDA and Shiro NAGAOKA. Central Re search Laboratory, Toyo Soda Mfg. Co., Ltd. -136(40)- 応 用 物 理 第54巻 第2号(1985) Table1 ポ リス チ レン誘 導 体 の電 子 線 に対 す る感 度.  ... 
doi:10.11470/oubutsu1932.54.135 fatcat:255phf4ktve5bmrx6ntpo5pzbe

Effect of Oral Valaciclovir on Herpetic Keratitis

Shiro Higaki, Motoki Itahashi, Tatsunori Deai, Masahiko Fukuda, Yoshikazu Shimomura
2006 Cornea  
Purpose: To examine the efficacy of valaciclovir (VACV) oral formulation as an alternative to topical treatments in a case of herpetic keratitis. Methods: The patient was a 61-year-old man who presented with dendritic keratitis in his left eye. After recognizing his difficulty in using eye ointment, we prescribed oral VACV 500 mg tablets twice daily for 7 days. We also describe our experiments with orally administered VACV in a mouse model of this disease. In this study, 143 Balb/c mice were
more » ... culated with herpes simplex virus type 1 (HSV)-1 in each eye and treated with oral VACV 50 or 100 mg/kg twice daily, oral acyclovir (ACV) 50 mg/kg 5 times/d, 3% ACV eye ointment (ACV-O) 5 times/d, 3% ACV eye drops 5 times/d, or control for 5 days. Results: After 7 days, the patient's lesion was observed healed. Corrected left visual acuity was also improved, and HSV DNA was below detectable level. In the mouse study, slit-lamp examination on days 3, 4, 5, and 7 revealed that all 5 ACV and VACV treatment groups were significantly more effective in improving symptoms of herpetic epithelial keratitis versus control (P , 0.05). Moreover, VACV 100 mg/kg was superior to other treatments. Viral titers in mouse eyeball and trigeminal ganglia were lowest in the VACV 100 mg/kg group versus other treatment groups. Conclusion: Our case example suggests that when frequent application, blurred vision, and foreign body sensation after ACV-O application cause difficulty for patients to follow treatment, oral VACV might be an effective and safe option for patients with herpetic keratitis.
doi:10.1097/01.ico.0000247216.08886.9d pmid:17001196 fatcat:t5vdlxx5svc6jkgus5xfqb66pi

76. Extremely Profound Hypothermia

1963 Neurologia medico-chirurgica  
Isolated Cerebral Vascular Irrigatin A-Methodological Study SAKAE FUKUDA, ISAO 0CHI, SHIGEO TOYA, SHIRO SHIMIZU, MOTOHIRO TANAKA and MITHuo HATTORI The extremely profound hypothermia was investigated upon  ...  Isolated Cerebral Vascular Irrigatin A-Methodological Study SAKAE FUKUDA, ISAO 0CHI, SHIGEO TOYA, SHIRO SHIMIZU, MOTOHIRO TANAKA and MITHuo HATTORI  ... 
doi:10.2176/nmc.5.101b fatcat:fjcqsjjwmrhwzlmwnuqjvhb2gm

Optically Anisotropic Texture in Tetrhydroqulnoline Soluble Matter of Carbomceous Mesophase

Yasuhiro Yamada, Shiro Matsumoto, Kenji Fukuda, Hidemasa Honda
1981 TANSO  
doi:10.7209/tanso.1981.144 fatcat:xinrz3krlrdmbnggjydqo4b4ve

Anesthetic Management for Surgical Gastrostomy in a Patient with Leigh Syndrome

2018 Yamaguchi Medical Journal  
Musashidai, Fuchu-shi, Tokyo 183-0042, Japan Anesthetic Management for Surgical Gastrostomy in a Patient with Leigh Syndrome Shiro FUKUDA, Nanae MIYAKE and Hiroaki MATAYOSHI SUMMARY underwent tracheostomy  ... 
doi:10.2342/ymj.67.155 fatcat:ngvia2p2sffk7mmbs45h3abhxu

Acute epidural hematoma due to spinal venous angioma: A case report

Shiro Chitoku, Iwao Nishiura, Miyuki Fukuda, Shigeru Amano
2018 Interdisciplinary Neurosurgery  
A B S T R A C T Background: Spinal epidural cavernous angioma was reported about 4% of all spinal epidural tumors, mostly generating as a primary lesion in the vertebral bone. Spinal epidural hematoma (SEDH) due to angioma without primary origin was very rare, which reported in the English literatures was only 10 cases including our case. The main symptoms were numbness and pains and motor weakness owing to the acute compression signs of cord and roots. Emergency surgical treatment was required
more » ... for the good surgical results. We present a rare case of cervical acute epidural hematoma due to ruptured venous angioma. Case presentation: A 78-year-old man, who suffered from sudden severe right suboccipitalgia., and sent to our hospital. He also noticed progressive numbness and motor weakness over his bilateral upper and lower extremities after the onset. Cervical CT and MRI showed acute intracanal hematoma over the right side of the cervical spine at C2 to C6. Emergency operation was performed 13 h after the onset. His sensory and motor symptoms were disappeared quickly after the operation. Pathological examination revealed spinal epidural hematoma due to venous angioma. Conclusion: This case presented with acute progressive deterioration of paresis and sensory disturbance, and required emergency operation. Early diagnosis and emergency surgical treatment are essential for the therapy of acute spinal epidural hematoma due to venous angioma.
doi:10.1016/j.inat.2017.11.007 fatcat:3cp32dejibdv5heasvotfcbw2e

Four cases of branchial cyst

Tadamasa SUGIYAMA, Hiroshi FUKUDA, Tatsundo TAMAI, Shiro KAWACHI, Masaki MASUDA, Takatoshi OHTANI
1976 Japanese Journal of Oral & Maxillofacial Surgery  
鰓 原 嚢 胞 の4例 杉 山 忠 正 ・福 田 広 志 ・玉 井 達 人 河 内 四 郎 ・増 田 正 樹 ・大 谷 隆 俊 Four cases of branchial cyst Tadamasa SUGIYAMA•EHiroshi FUKUDA •E Tatsundo TAMAI Shiro KAWACHI •E Masaki MASUDA •E Takatoshi OHTANI 緒 言 鯛  ... 
doi:10.5794/jjoms.22.563 fatcat:cb326gtynbbmdlhdy47mnithea

Arch-first technique through left antero-axillary thoracotomy orbilateral anterior thoracotomy

Shiro Sasaguri, Tomonobu Fukuda
1999 Journal of Thoracic and Cardiovascular Surgery  
The pericardial stitch, which is placed at the corner of the pericardial reflection on We appreciate the comments of Sasaguri and Fukuda.  ... 
doi:10.1016/s0022-5223(99)70166-2 pmid:10419379 fatcat:fwr3k5pe2vbfhkpi26lofqadau

55. Statistical Survey of Cerebral Aneurysm

Tatsuyuki KUDO, Shoji ISHIMORI, Takashi TOMITA, Motohiro TANAKA, Michihiko MATSUSHITA, Sakae FUKUDA, Hideyuki HIRAI, Isao OCHI, Shiro SHIMIZU, Masaki MORIYAMA
1967 Neurologia medico-chirurgica  
doi:10.2176/nmc.9.89 fatcat:yy4jmajb65cdjdkii42nivswuu

Fusiform Aneurysm Associated With Fenestration of the Posterior Communicating Artery

Shiro BABA, Yuutaka FUKUDA, Shingo MIZOTA, Kentaro HAYASHI, Kazuhiko SUYAMA, Izumi NAGATA
2010 Neurologia medico-chirurgica  
Fig. 1 (A) Left internal carotid angiogram, lateral view, showing a saccular aneurysm at the C 2 segment of the left internal carotid artery (ICA). (B) Three-dimensional digital subtraction angiogram showing the larger branch originating from the dome, and the smaller branch (arrow) originating from the ICA just distal to the aneurysm neck, which joined the larger branch to form the main trunk of the posterior communicating artery. Abstract A 62-year-old male presented with a rare case of
more » ... ration of the supraclinoid segment of the internal carotid artery (ICA) at the origin of the posterior communicating artery (PCoA). The patient had a fusiform aneurysm at the proximal branch of the PCoA, which was successfully clipped, sparing the anterograde blood flow. The double origin and fenestration of the PCoA branching off at the C 2 segment of the left ICA suggested that this anomalous fenestration might have developed as the origin of the PCoA rather than the supraclinoid ICA during the early embryonal stage.
doi:10.2176/nmc.50.568 pmid:20671382 fatcat:4sse3x5a5jd7dlm4nym5tai3xa


Eiichi Ogawa, Shiro Suzuki, Jun-ichi Machida, Ryuzo Fukuda, Yutaka Hayashi, Kinzo Horikawa
1959 The Kitikanto Medical Journal  
doi:10.2974/kmj1951.9.1100 fatcat:kljunnfmlzhohgt4ywchbdc76e

Native adiponectin in serum binds to mammalian cells expressing T-cadherin, but not AdipoRs or calreticulin

Shunbun Kita, Shiro Fukuda, Norikazu Maeda, Iichiro Shimomura
2019 eLife 5061/dryad.82557c0 Dryad Digital Repository, 10.5061/ dryad.82557c0 Decision Additional files Author(s) Year Dataset title Dataset URL Database and Identifier Kita S, Fukuda  ... 
doi:10.7554/elife.48675 pmid:31647413 pmcid:PMC6822988 fatcat:g5sbsi66qfgm5owbwfy5n3rnli


Eiichi Ogawa, Shiro Suzuki, Jun-ichi Machida, Yutaka Hayashi, Ryuzo Fukuda, Kinzo Horikawa
1959 The Kitikanto Medical Journal  
doi:10.2974/kmj1951.9.1104 fatcat:nbvc5jtwrvcb5j5kcvbjpygzua

Hidden layers of human small RNAs

Hideya Kawaji, Mari Nakamura, Yukari Takahashi, Albin Sandelin, Shintaro Katayama, Shiro Fukuda, Carsten O Daub, Chikatoshi Kai, Jun Kawai, Jun Yasuda, Piero Carninci, Yoshihide Hayashizaki
2008 BMC Genomics  
Small RNA attracts increasing interest based on the discovery of RNA silencing and the rapid progress of our understanding of these phenomena. Although recent studies suggest the possible existence of yet undiscovered types of small RNAs in higher organisms, many studies to profile small RNA have focused on miRNA and/or siRNA rather than on the exploration of additional classes of RNAs. Results: Here, we explored human small RNAs by unbiased sequencing of RNAs with sizes of 19-40 nt. We provide
more » ... substantial evidences for the existence of independent classes of small RNAs. Our data shows that well-characterized non-coding RNA, such as tRNA, snoRNA, and snRNA are cleaved at sites specific to the class of ncRNA. In particular, tRNA cleavage is regulated depending on tRNA type and tissue expression. We also found small RNAs mapped to genomic regions that are transcribed in both directions by bidirectional promoters, indicating that the small RNAs are a product of dsRNA formation and their subsequent cleavage. Their partial similarity with ribosomal RNAs (rRNAs) suggests unrevealed functions of ribosomal DNA or interstitial rRNA. Further examination revealed six novel miRNAs. Conclusion: Our results underscore the complexity of the small RNA world and the biogenesis of small RNAs.
doi:10.1186/1471-2164-9-157 pmid:18402656 pmcid:PMC2359750 fatcat:3cdgijy76jhv7a62iksyo44swy
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