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Lecture Notes in Computer Science
This paper modifies and extends Potts and Roeper's (2006) analysis of simple uses of epithets such as You fool!, what they call Expressive Small Clauses, to analogous phrases in Japanese. The original Potts and Roeper analysis is unable to account for two puzzling characteristics of Japanese Expressive Small Clauses, which we cannot observe in those in English: first, the use of a second person pronoun is not permitted in the Japanese counterparts, whereas many other forms of pronouns anddoi:10.1007/978-3-319-93794-6_13 fatcat:wniyaxru6rgdfmuxbspmmrhg4y
more »... onominal nouns are available; and second, something like "you fool" in Japanese can indeed occur as an argument of a sentence. Drawing on the recent syntactic literature on the morphological variation of analogous uses of epithets, we propose an account that explains why there are differences between English and Japanese Expressive Small Clauses.
Hopkins syndrome (HS) is a rare disorder presenting with acute flaccid paralysis of the limbs following an asthma attack. Neurologists encounter a diagnostic challenge if patients without a history of bronchial asthma develop neurologic features mimicking HS following acute respiratory distress. We report a case of HS occurring after a first episode of bronchial asthma associated with enterovirus D68 infection. Case presentation: A 5-year-old girl developed acute respiratory distress. On thedoi:10.1186/s12883-018-1075-7 pmid:29792179 pmcid:PMC5966892 fatcat:lbcjy4lpwfah7deplf6uk6r4hu
more »... rth hospital day, both her legs became paralyzed except for slight muscle contraction in the right lower limb. Tendon reflexes in the lower limbs were diminished and there was a positive Babinski sign on the right. Sensation was normal in all modalities, and there was no uro-rectal disturbance. Spinal magnetic resonance imaging identified T2-hyperintense lesions with spinal cord edema, mainly involving the bilateral T11 to L1 anterior horns, with left side dominance extending to the left posterior horn. The neurological and neuro-radiological findings of our case were suggestive of HS; however, she had no history of bronchial asthma. An acetylcholine inhalation challenge eventually proved the presence of reversible airway hyperresponsiveness, allowing us to diagnose HS. We identified enterovirus D68 in the patient's intratracheal aspirates using a sensitive polymerase chain reaction assay. Intravenous immunoglobulin administrations at 2 g/kg 2 for 5 consecutive days were repeated every month up to four times. After these treatments, the muscle strength of her right lower limb slightly improved while her left lower leg remained completely paralyzed. Conclusion: This case emphasizes the importance of provocation tests to reveal the presence of airway hyperresponsiveness when a child shows neurological signs mimicking HS following acute respiratory distress. Furthermore, the present case suggests a possible link between HS and acute flaccid paralysis following lower respiratory tract infection by enterovirus D68.
Photo : Motomaro SHIRAO, Comentary : Shintaro HAYASHI and Motomaro SHIRAO) ...doi:10.5026/jgeography.107.2_plate3 fatcat:l4ofdbdkdfcizecjyj7wfhpbzm
Journal of JSEE
ITO Shunsuke AOKI Yugo HAYASHI Previous studies show that Worked-out examples improve more learning effects than simply solving problems in the initial stage of cognitive skill acquisition. ... Worked-out example の重要性 を指摘している 5) ， 10) ．Product-oriented Worked-out example と，Process-oriented Worked-out example 平成 23 年5月 10 日受付 ※1鈴鹿工業高等専門学校 ※2立命館大学情報理工学部 熟達度の違いが例題学習の効果に及ぼす影響 Akira URAO Shintaro ...doi:10.4307/jsee.59.6_86 fatcat:7mt5pqgbl5hgzixa5ssfgo5vx4
It has recently been reported that voltage-dependent Ca channel subtypes, e.g., L-, T-, N-, and P/Q-type, are expressed in renal arterioles and renal tubules, and the inhibition of these channels exerts various effects on renal microcirculation. For example, selective blockade of L-type Ca channels with nifedipine preferentially dilates the afferent arteriole and potentially induces glomerular hypertension. On the other hand, recently developed Ca channel blockers (CCBs) such as mibefradil anddoi:10.2174/1573402110666140131160617 pmid:24479750 pmcid:PMC4033552 fatcat:4ziyrbzagzaifpzfz3llm64dke
more »... fonidipine block both T-type and L-type Ca channels and consequently dilate both afferent and efferent arterioles, leading to lowering of intraglomerular pressure. Interestingly, aldosterone has recently been recognized as a factor exacerbating renal diseases, and its secretion from adrenal gland is mediated by T-type Ca channels. Furthermore, T-type CCBs were shown to ameliorate renal dysfunction by suppressing inflammatory processes and renin secretion. On the basis of histological evaluations, N-type Ca channels are present in peripheral nerve terminals innervating both afferent and efferent arterioles. Further, it was suggested that N-type CCBs such as cilnidipine suppress renal arteriolar constriction induced by enhanced sympathetic nerve activity, thereby lowering intraglomerular pressure. Taken together, various Ca channel subtypes are present in the kidney and blockade of selective channels with distinct CCBs exerts diverse effects on renal microcirculation. Inhibition of T-type and N-type Ca channels with CCBs is anticipated to exert pleiotropic effects that would retard the progression of chronic kidney disease through modulation of renal hemodynamic and non-hemodynamic processes.
ITE Technical Report
Transmission Characteristics of the Digital Facsimile Broadcasting
Transmission Characteristics of the Digital Facsimile Broadcasting
., Hayashi, S., Yanai, K., Ishizuka, O., Miyagi, I. and Ishiyama, D., 2020, Tazawako caldera, NE Japan and its eruption products.J. Geol.Soc.Japan,126, 233-249.) ...doi:10.5575/geosoc.2020.0001 fatcat:answoozperfx3jkwxrln52acui
Sivelestat is a neutrophil elastase inhibitor (NEI) with positive impact on the respiratory complications in thoracic surgery. Based on the findings of a recent study, NEI may have a good response for avoiding ischemia reperfusion injury in liver resection. Objectives: The current study aimed to examine the impact of NEI on the postoperative outcomes after liver resection. Patients and Methods: The data were collected from 374 consecutive patients scheduled to undergo liver resection. Sevendoi:10.5812/hepatmon.31235 pmid:26834789 pmcid:PMC4716668 fatcat:mlmgiip2t5bmdn4gofrfumcd3y
more »... operative variables were matched on the basis of the patients' background. Then, the NEI (n = 61) and control (n = 61) groups were compared. NEI was administered at a dose of 0.2 mg/kg/h for three days from the postoperative day 0 (POD0). The liver function, coagulation activity, inflammatory response, respiratory complications, and overall complications were compared. Results: The levels of serum interleukin-6 (NEI group: 113 pg/mL [26.9 -522.0] vs. control group: 174 [28.6 -1040.6], P < 0.01) and C-reactive protein (CRP) (2.9 IU/L [range: 0.1 -8.6] vs. 4.11 [0.3 -13.8], P = 0.01) on the first postoperative day (POD1) and the alveolar-arterial oxygen tension difference (32.3 Torr [-28.6 -132.3] vs. 46.6 [-11.2 -251.6], P = 0.04) on the third postoperative day (POD3) were significantly lower in the NEI group than the control group. The rate of pleural effusion was significantly lower in the NEI group compared to that of the control group [13 patients (21.3%) vs. 23 (37.7%), P = 0.04]. However, the coagulation activities (P = 0.68), liver function (P = 0.69), non-respiratory complications (P = 0.84), and overall complications (P = 0.71) did not differ significantly between the groups. Conclusions: Intravenous NEI administration had positive impact on the postoperative inflammatory response and oxygenation while it did not affect either coagulation or the liver function, as well as severe grade complications following resection.
T helper 17 (Th17) cells that produce Interleukin (IL)-17A and IL-17F have been found to participate in the development of bronchial asthma and bleomycin-induced pulmonary fibrosis. However, whether they play a causative role in the airway remodeling observed in these respiratory diseases remains unclear. Because fibrocytes are involved in tissue repair and fibrosis, and are presumably precursors of lung fibroblasts and myofibroblasts, we examined the effects of IL-17A/F on fibrocyte functions.doi:10.1007/s10753-013-9609-z pmid:23400328 fatcat:7be4rclrizgjxeumo44lgowmcm
more »... Both IL-17A and IL-17F enhanced fibrocytes' asmooth muscle actin (SMA) expression. Priming fibrocytes with IL-17A enhanced their CD40-mediated IL-6 production, whereas IL-17F-priming increased the CD40-mediated mRNA expression of collagen I, vascular endothelial growth factor (VEGF), and angiogenin. CD4+ T cells co-cultured with fibrocytes produced IL-17A, which was inhibited by blocking CD40 and CD40 ligand interactions. These findings suggest that cooperative interactions between fibrocytes and Th17 cells play an important role via CD40-and IL-17A/F-mediated signaling for collagen and proangiogenic factor production, which may lead to the extracellular matrix deposition and neo-vascularization seen in airway remodeling.
Background. There have only been a few studies that visualized the human coronary tree continuously from coronary arteries to capillaries in the clinical setting. The purpose of this study was to visualize the human coronary tree noninvasively with myocardial contrast echocardiography (MCE) by changing frame rates. Methods. MCE was performed intravenously using TM Levovist. Study population consisted of 20 patients with ischemic heart disease. We performed 3 kinds of MCE: intermittent,doi:10.2303/jecho.5.21 fatcat:sqew2rngkvgfjiatwby2ebg2jq
more »... , and real-time harmonic imaging. Results. 1. Myocardial blood flow velocity and volume were obtained from the time-intensity replenishment curve with intermittent imaging. Curve fitting was possible in 75% of the targeted region of interest. 2. Semi-real-time perfusion image was obtained with a frame rate of 5/sec. We observed a cyclic variation of echo-intensity in one cardiac cycle in only viable region (Peak subtracted signal intensity: 53 29 in end-diastole and 33 27 in end-systole, p<0.05). This phenomenon may result from the compression of arterioles according to cardiac beat. 3. Real-time perfusion image was obtained at a rate of 26 frames/sec. We observed line-form small artery flows in 80 % of the viable area. Conclusions. Thus, coronary tree following major epicardial coronary arteries was visualized non-invasively from the small artery to the capillary bed with 3-staged intravenous-MCE in the clinical setting. (J Echocardiogr 2007; 5: 21-27)
A 45-year-old woman under home parenteral nutrition was admitted with recurrent fever and a worsening renal function. A diagnosis of central venous catheter-related blood stream infection (CVCRBSI) was made according to the identification of coagulase-negative Staphylococcus from both the peripheral blood and the removed CV catheter, along with an improvement of the symptoms following the removal of the catheter. Renal impairment with hypocomplementemia was thought to be secondary to the immunedoi:10.2169/internalmedicine.54.4607 pmid:26328650 fatcat:yasxrge2rrc7vpscqc4lf4hbxm
more »... complex formation and deposition in the kidneys in response to prolonged bacteremia. This was confirmed by the pathological findings. Clinicians should therefore be aware that glomerulonephritis may be induced by long-term CVCRBSI.
doi:10.1046/j.1440-1789.2002.00468.x pmid:12564780 fatcat:y5jscenltfexxj4qidzsxn3jmm
Introduction ! The early detection and treatment of gastric cancer are necessary to reduce mortality , although surgery is the standard treatment. Esophagogastroduodenoscopy (EGD) is useful for the detection of early gastric cancer because this technique can identify superficial flat and nonulcerative lesions. The suppression of gastric peristalsis promotes the detection of smaller lesions because it facilitates EGD [2, 3]. Thus, antispasmodic agents such as butyl scopolamine bromide anddoi:10.1055/s-0034-1377172 pmid:26135260 pmcid:PMC4423322 fatcat:varxhn2s55bptm6s5xerzx63qa
more »... agon are often injected before EGD to suppress gastric peristalsis. However, complications associated with these antispasmodic agents, including cardiovascular events and reactive hypoglycemia, have been reported [4, 5] . Therefore, endoscopists should consider these complications, particularly in elderly patients. The intragastric administration of L-Menthol (LM) was found to reduce gastric spasm during EGD and to be more effective than the intramuscular injection of butyl scopolamine bromide [2, 6] . The use of LM as an alternative antispasmodic agent would increase the safety of EGD, even in elderly patients  , with a possibly better detection of gastric lesions. We have therefore used LM as an antispasmodic agent. On one occasion, however, we noted that directly spraying LM onto the distal stomach caused a specific endoscopic mucosal changenamely, annular and/or reticular edematous thickeningjust after administration (• " Fig. 1, • " Fig. 2) . The change seemed to occur mainly in mucosa affected with atrophic gastritis. Hikichi and colleagues reported that the intragastric administration of LM emphasized the margin of gastric cancer because the mucosa around the tumor became edematous  . However, limited information is available regarding the impact of LM on the gastric mucosa. The aim of the present study therefore was to evaluate whether LM causes specific gas-Mori Akihiro et al. Effect of L-Menthol on gastric mucosa ... Endoscopy International Open 2014; 02: E51-E57 Background and study aims: L-Menthol (LM), sprayed on the distal gastric mucosa, is a safe antispasmodic agent used during esophagogastroduodenoscopy (EGD). However, it seems to affect gastric mucosal endoscopic findings. Therefore, we evaluated whether LM causes specific changes and impacts the endoscopic morphology of gastric lesions. Patients and methods: A total of 98 patients scheduled to undergo EGD were randomly assigned to receive LM solution (160 mg of 0.8 % LM added to 2.5 mL of indigo carmine [IC]; n = 49; LM group) or decuple-diluted IC solution without LM (n = 49; placebo group). We compared the incidence of specific mucosal changes and the difference in the endoscopic findings of several gastric lesions between these groups. Results: Annular-reticularlike mucosal changes appeared immediately after the administration of LM solution. This change was observed in
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