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Association of CYP2E1 gene polymorphisms with bladder cancer risk

Xiangrui Yin, Wei Xiong, You Wang, Wei Tang, Wang Xi, Shengqiang Qian, Yu Guo
<span title="">2018</span> <i title="Ovid Technologies (Wolters Kluwer Health)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/2fgvdq2bsrdtbigpwmptmgucfm" style="color: black;">Medicine</a> </i> &nbsp;
Human cytochrome P450 (CYP) is an enzyme responsible for the metabolic activation of many carcinogens, including nitrosamines. CYP2E1 represents a major CYP isoform and is expressed in the human urothelial cells. Recent studies have investigated the association of CYP2E1 gene polymorphisms with bladder cancer risk but have shown contradictory results. Hence, we performed a systematic literature review and meta-analysis to assess the association between CYP2E1 gene polymorphisms and bladder
more &raquo; ... r. Methods: Systematic literature searches were conducted with PubMed, Excerpt Medica Database, Science Direct/Elsevier, China National Knowledge Infrastructure, and the Cochrane Library up to January 2018 for studies that involved the association of CYP2E1 gene polymorphisms with bladder cancer risk. A meta-analysis was performed with Review Manager and Stata software. Combined odds ratios (ORs) were identified with 95% confidence intervals (CIs) in a random or fixed effects model. Ethics: The protocol was approved by the institutional review board of each study center. Written informed consent will be obtained from all patients before registration, in accordance with the Declaration of Helsinki. Results: Eight studies were identified, including 1733 cases of bladder cancer and 1814 normal controls. Our results illustrated that there are significant associations between CYP2E1 gene polymorphisms and bladder cancer in all genetic models (P < .05). The combined ORs and 95% CIs were as follows for each model: additive model [OR 0.56; 95% CI (0.38-0.82)]; dominant model [OR 0.79; 95% CI (0.67-0.93)]; recessive model [OR 0.61; 95% CI (0.41-0.89)]; codominant model [OR 0.80; 95% CI (0.67-0.96)]; allele model [OR 0.75; 95% CI (0.59-0.95)] . A subgroup study showed that there are also significant associations between CYP2E1 gene polymorphisms and bladder cancer in Asian people. However, there are no significant associations between CYP2E1 gene polymorphisms and bladder cancer in Caucasian populations. Conclusions: The present study provides evidence for an association between CYP2E1 gene polymorphisms and bladder cancer progression, and suggests that CYP2E1 gene polymorphisms might be a protective factor against bladder cancer in Asian people. However, studies with larger sample sizes are needed to confirm the correlation between CYP2E1 gene polymorphisms and bladder cancer. Abbreviations: CI = confidence interval, CYP = cytochrome P450, OR = odds ratio, SNP = single nucleotide polymorphism.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1097/md.0000000000011910">doi:10.1097/md.0000000000011910</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/30278485">pmid:30278485</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6181476/">pmcid:PMC6181476</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/apw7u445djf4pcpwhpdkue6urq">fatcat:apw7u445djf4pcpwhpdkue6urq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190225092339/http://pdfs.semanticscholar.org/60ae/b89219d951e3fea20c090ff128a98349e3bd.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/60/ae/60aeb89219d951e3fea20c090ff128a98349e3bd.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1097/md.0000000000011910"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181476" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Hepatic Metastasis in Newly Diagnosed Esophageal Cancer: A Population-Based Study

Huawei Li, Shengqiang Zhang, Jida Guo, Linyou Zhang
<span title="2021-05-10">2021</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/mefn5t5kjndavkrqau5bzfpaoe" style="color: black;">Frontiers in Oncology</a> </i> &nbsp;
Copyright © 2021 Li, Zhang, Guo and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fonc.2021.644860">doi:10.3389/fonc.2021.644860</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34041021">pmid:34041021</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8143266/">pmcid:PMC8143266</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/5thaz2hozrfm3du3bc75dryro4">fatcat:5thaz2hozrfm3du3bc75dryro4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210511043047/https://fjfsdata01prod.blob.core.windows.net/articles/files/644860/pubmed-zip/.versions/2/.package-entries/fonc-11-644860.pdf?sv=2018-03-28&amp;sr=b&amp;sig=nmMDN5cKQW0UqHVmhfPwPPFxHDlUFRB3AnD%2FxiImV9U%3D&amp;se=2021-05-11T04%3A31%3A17Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fonc-11-644860.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/8a/e2/8ae23af6071c8e03d86159f1a4aaa4caba752967.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fonc.2021.644860"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143266" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

The Effect of Different Pressure Conditions on Shock Waves in a Supersonic Steam Ejector

Yiqiao Li, Shengqiang Shen, Chao Niu, Yali Guo, Liuyang Zhang
<span title="2022-04-15">2022</span> <i title="MDPI AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/a2yvk5xhdnhpxjnk6yd33uudqq" style="color: black;">Energies</a> </i> &nbsp;
The complex flow phenomena in a three-dimensional supersonic steam ejector were simulated with a non-equilibrium condensation model including real physical properties in different pressure conditions. The different working conditions include discharge pressure, motive pressure, and suction pressure. The influence of different pressures on shock waves in the steam ejector was investigated comprehensively. The intrinsic causes of shock wave variation with pressure conditions were explained in
more &raquo; ... il. The results show that the width of the primary shock train region expand with an increase in the motive pressure or a decrease in suction pressure. The diamond shock waves move downstream with an increase in motive pressure or a decrease in suction pressure. The shocking position in the diffuser moves upstream until it reaches the diffuser entrance with an increase in discharge pressure or a decrease in motive pressure or suction pressure. The intensity and number of oblique shock waves in the diffuser increase with an increase in motive pressure and suction pressure or a decrease in discharge pressure. The existence of only one shock wave in the diffuser is a necessary and insufficient condition for the ejector to enter a double choking mode.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/en15082903">doi:10.3390/en15082903</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ytvnvygxprbbnoyvdjt5gdkzxi">fatcat:ytvnvygxprbbnoyvdjt5gdkzxi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20220520233737/https://mdpi-res.com/d_attachment/energies/energies-15-02903/article_deploy/energies-15-02903-v2.pdf?version=1650530797" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/92/f2/92f25ab97f01815a74c790d3d04b0e8e06d54c91.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/en15082903"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> mdpi.com </button> </a>

Tailoring nonlinear optical properties of Bi2Se3 through ion irradiation

Yang Tan, Zhinan Guo, Zhen Shang, Fang Liu, Roman Böttger, Shengqiang Zhou, Jundong Shao, Xuefeng Yu, Han Zhang, Feng Chen
<span title="2016-02-18">2016</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/tnqhc2x2aneavcd3gx5h7mswhm" style="color: black;">Scientific Reports</a> </i> &nbsp;
The nonlinear optical property of topological insulator bismuth selenide (Bi 2 Se 3 ) is found to be welltailored through ion irradiation by intentionally introducing defects. The increase of the optical modulation depth sensitively depends on the careful selection of the irradiation condition. By implementing the ion irradiated Bi 2 Se 3 film as an optical saturable absorber device for the Q-switched wave-guide laser, an enhanced laser performance has been obtained including narrower pulse
more &raquo; ... tion and higher peak power. Our work provides a new approach of tailoring the nonlinear optical properties of materials through ion irradiation, a well-developed chip-technology, which could find wider applicability to other layered two-dimensional materials beyond topological insulators, such as graphene, MoS 2 , black phosphours etc. Two-dimensional (2D) materials have received great scientific and technical attentions in research areas of physics, chemistry, and materials sciences 1,2 . In optics, peculiar optical performances have been found in 2D materials including polarization dependent absorption and nonlinear optical absorption 3-5 . Besides, 2D materials can be easily integrated with photonic structures such as waveguides and cavities, since the surfaces of 2D materials can be passivated without any dangling bonds. Based on the unique optical properties of 2D materials, many important optical applications have been realized in integrated photonics, including waveguide polarizers, mode-locked, waveguide amplifier 6 and Q-switched waveguide lasers 3,7-11 . Taking the Q-switched pulsed waveguide laser for example, a waveguide structure with doping of rare-earth ions could be used as the gain medium and 2D materials with the saturable absorption property can be coated onto the waveguide facet as broadband optical saturable absorbers. Properties of 2D materials can be tailored by doping and external electric field. Recently, it has been demonstrated that the ion irradiation can also induce beneficial effects to nanostructured materials 12-15 . The interaction of energetic particles (e.g. electrons or ions) normally generates atomic defects in the target and changes properties of the materials. In spite of defects, the ion irradiation process may bring a positive effect to the material, in some cases. For example, the atomic constitution and morphology of graphene can be changed in a controllable manner by ion irradiation 16 . For nanotubes, ion irradiation can interconnect and merge the nanotubes, induce extreme pressure and lead to the formation of fullerene like "onions" in the nanotube 17 . In addition, it has been proved that the mechanical, electronic and even magnetic properties of nanostructured materials can be tailored by ion irradiation 18-20 . Nevertheless, there have been no reports on tailoring the optical properties of 2D materials by ion irradiation as of yet. The Bi 2 Se 3 film, as a prototype topological insulator (TI), possesses an excellent saturable absorption and has been applied in Q-switched laser as the saturable absorber 21, 22 . In this work, we applied the ion irradiation to modify the nonlinear optical property of the Bi 2 Se 3 film in constructive way. The Bi 2 Se 3 films have been irradiated
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/srep21799">doi:10.1038/srep21799</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26888223">pmid:26888223</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4757877/">pmcid:PMC4757877</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/g76suyaxvjcdxa6yzel7funp5m">fatcat:g76suyaxvjcdxa6yzel7funp5m</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190217125850/http://pdfs.semanticscholar.org/0549/8c3b5cf3497fe423872e4f205a38f31518f5.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/05/49/05498c3b5cf3497fe423872e4f205a38f31518f5.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/srep21799"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757877" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Fracture mechanics modeling of popping event during daughter cell separation

Yuxuan Jiang, Xudong Liang, Ming Guo, Yanping Cao, Shengqiang Cai
<span title="2018-05-10">2018</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/7ofs3f2ch5clzlmufw5ukbtcg4" style="color: black;">Biomechanics and Modeling in Mechanobiology</a> </i> &nbsp;
Most bacteria cells divide by binary fission which is part of a bacteria cell cycle and requires tight regulations and precise coordination. Fast separation of Staphylococcus Aureus (S. Aureus) daughter cells, named as popping event, has been observed in recent experiments. The popping event was proposed to be driven by mechanical crack propagation in the peripheral ring which connected two daughter cells before their separation. It has also been shown that after the fast separation, a small
more &raquo; ... tion of the peripheral ring was left as a hinge. In the article, we develop a fracture mechanics model for the crack growth in the peripheral ring during S. Aureus daughter cell separation. In particular, using finite element analysis, we calculate the energy release rate associated with the crack growth in the peripheral ring, when daughter cells are inflated by a uniform turgor pressure inside. Our results show that with a fixed inflation of daughter cells, the energy release rate depends on the crack length non-monotonically. The energy release rate reaches a maximum value for a crack of an intermediate length. The non-monotonic relationship between the energy release rate and crack length clearly indicates that the crack propagation in the peripheral ring can be unstable. The computed energy release rate as a function of crack length can also be used to explain the existence of a small portion of peripheral ring remained as hinge after the popping event.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s10237-018-1019-6">doi:10.1007/s10237-018-1019-6</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29748837">pmid:29748837</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/g4oyjdpddrh6ljnefautelqgu4">fatcat:g4oyjdpddrh6ljnefautelqgu4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190307214808/http://pdfs.semanticscholar.org/dd60/52a056c8937d64e68bbafa696028a1c4574e.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/dd/60/dd6052a056c8937d64e68bbafa696028a1c4574e.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s10237-018-1019-6"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a>

Synthesis and Enzyme Substrate Activity of p-Nitrophenyl N,N'-Diacetyl-4-thio-β-chitobioside

Bingbo Guo, Shengqiang Shen, Shuhui Jin, Huizhe Lu, Jianjun Zhang
<span title="">2019</span> <i title="Shanghai Institute of Organic Chemistry"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/mpz5xloylnh7ze6mdwj2zim73u" style="color: black;">Youji huaxue</a> </i> &nbsp;
Based on the resistance of glycosidase to the hydrolysis of glycosidase, the probe molecule p-nitrophenyl N,N'diacetyl-4-thio-β-chitobioside (pNP-TCB) was designed and synthesized. The effects of pNP-TCB on the degradation of glycoside hydrolase family 18 (GH18) chitinase and 20 (GH20) β-N-acetylhexosaminidase were studied. The results showed that when pNP-TCB was combined with β-N-acetylhexosaminidase, the disaccharide substrate was hardly degraded. But when it reacted with chitinase, the
more &raquo; ... CB was degraded by enzyme to release p-nitrophenol group, and the corresponding ultraviolet absorption value can be detected by enzyme-labeled instrument at 405 nm. It indicates that the substrate molecule exhibits good specificity, which can be used to study the properties of GH18 chitinase at the cellular level without interference of β-N-acetylhexosaminidase. The pNP-TCB can also provide a good detection method for screening and isolation between the GH18 chitinase and the GH20 β-N-acetyl hexose.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.6023/cjoc201906008">doi:10.6023/cjoc201906008</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ffnqtfrbnjgodfyw3swpemwb4q">fatcat:ffnqtfrbnjgodfyw3swpemwb4q</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210716065325/http://sioc-journal.cn/Jwk_yjhx/EN/article/downloadArticleFile.do?attachType=PDF&amp;id=347309" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/21/2b/212b5b28f2690b5730bea2e2266b4aa0c6be134b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.6023/cjoc201906008"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Lung Metastases in Newly Diagnosed Esophageal Cancer: A Population-Based Study

Jida Guo, Shengqiang Zhang, Huawei Li, Mohamed Osman Omar Hassan, Tong Lu, Jiaying Zhao, Linyou Zhang
<span title="2021-02-25">2021</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/mefn5t5kjndavkrqau5bzfpaoe" style="color: black;">Frontiers in Oncology</a> </i> &nbsp;
Guo et al.  ...  b Guo et al.  ...  Copyright © 2021 Guo, Zhang, Li, Hassan, Lu, Zhao and Zhang. This is an openaccess article distributed under the terms of the Creative Commons Attribution License (CC BY).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fonc.2021.603953">doi:10.3389/fonc.2021.603953</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33718154">pmid:33718154</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7947855/">pmcid:PMC7947855</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/iqorge3harhehfbgz7c75ckoam">fatcat:iqorge3harhehfbgz7c75ckoam</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210301054523/https://fjfsdata01prod.blob.core.windows.net/articles/files/603953/pubmed-zip/.versions/1/.package-entries/fonc-11-603953.pdf?sv=2018-03-28&amp;sr=b&amp;sig=sgoLAzydyDN%2FRcXlPkr0%2BY7KiZo45THvCMNMVoEf8TA%3D&amp;se=2021-03-01T05%3A45%3A53Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fonc-11-603953.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/55/a7/55a719e8ba3de09985413b4f3205e364aeb0606e.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fonc.2021.603953"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947855" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Analysis of energy utilization coefficient in heat, power and gas cogeneration system

Zhongyou Zhao, Yali Guo, Shengqiang Shen
<span title="">2008</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/vukjss4tszb53ldntuikcvs6fa" style="color: black;">International Journal of Low-Carbon Technologies</a> </i> &nbsp;
This study presents the thermodynamic model of a heat, power and gas cogeneration system. The energy utilization coeffi cient m, which is the ratio of the sum of gas calorifi c value and heat supplied to the boiler to the low calorifi c value of coal, is used as a criterion to evaluate the performance of the multi-production system. The emphasis was placed on the vaporization of the coal and the combustion in the boiler. For gas output 10,000 m 3 ·h −1 and boiler steam load 130 t·h −1 , the
more &raquo; ... ge of gross coal consumption and energy available coeffi cient m of the cogeneration system is calculated at different pyrogenation temperatures with three types of coals. The results show that the energy available coeffi cient has a maximum value for the cogeneration system, and the gross coal consumption of the cogeneration system is lower than that of two separation systems. In a large range of feeding coal to the boiler, the system gross coal consumption reaches its minimum value and the energy available coeffi cient m reaches maximum when pyrogenation temperature is 700°C. And the optimal is realized at a higher temperature.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/ijlct/3.3.139">doi:10.1093/ijlct/3.3.139</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/nh2wfwrkijgq7hnkehuvf6bh3q">fatcat:nh2wfwrkijgq7hnkehuvf6bh3q</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180729145324/https://watermark.silverchair.com/3-3-139.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAaIwggGeBgkqhkiG9w0BBwagggGPMIIBiwIBADCCAYQGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMDl-TgbGGOKkjKmD7AgEQgIIBVYTMfiAjk3P7UO2ssSlmR7L5u9XqIH7IZv21YPSt9kk2swuVDhsVvRR5lI69Twe2QfmGqpFeQchNgnMqW0DFFieO8aHJUCHjeAeG4B4QzmrKi_ib_gC2dJjiYACJiVTIXTKlCuHzVlNV26sKjzCNUKpzXsjP6Dt8OgTdzCkI91jU-LjqAIX3DCX7RFHm8VUaz9IlJQq9KWKY85z8zsvQu-vL1YEgpgWKzeyj5WZamhQQW12CuAEWAHBsHFJfm-qOLXjzsqRDM-CryIQQPVpFLBiMhbbbfiUGvarF2rqtwR3dxpo6ROdIoxOBoR11SOoTCGENBGaayvJymy8iFutqh4yTs8KZ9uaG5CtxoIQFrB3rIHmpiYBB-pIylVUG55uS-OH1W4CxDlTlMBuKcehSRAAvRhB21BcmrBvDHAI_VLAaL5IdpGd0Pg9T4H5NcGmQtHN6jvGS" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/59/0f/590fb6d07d634d7435f25a8886f37753ff68ede4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/ijlct/3.3.139"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> oup.com </button> </a>

Vaginal Secretions Epithelial Cells and Bacteria Recognition Based on Computer Vision

Shaozhi Guo, Haoyuan Guan, Jianzhong Li, Yonghua Liao, Weiwen Zhang, Shengqiang Chen, Zhan Li
<span title="2020-12-01">2020</span> <i title="Hindawi Limited"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/wpareqynwbgqdfodcyhh36aqaq" style="color: black;">Mathematical Problems in Engineering</a> </i> &nbsp;
Authors' Contributions Shaozhi Guo and Haoyuan Guan contributed equally to this work.  ...  Disclosure Shaozhi Guo and Haoyuan Guan are co-first authors. Conflicts of Interest e authors declare that they have no conflicts of interest.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1155/2020/8863147">doi:10.1155/2020/8863147</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ydmzcfmk3vd6voqwipdihqbpiy">fatcat:ydmzcfmk3vd6voqwipdihqbpiy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20201205181224/http://downloads.hindawi.com/journals/mpe/2020/8863147.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/68/8a/688a2c94f2cc4a27e4a1b522e772afefc5058eb4.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1155/2020/8863147"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> hindawi.com </button> </a>

Mechanical, Tribological, and Oxidation Resistance Properties of NiCrAlY Coating by Atmospheric Plasma Spraying

Bo Li, Shengqiang Ma, Yimin Gao, Cong Li, Hongjian Guo, Qiaoling Zheng, Yunchuan Kang, Junhong Jia
<span title="2019-05-08">2019</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/uunhnq4jsbhmpkcnw2uws7hiie" style="color: black;">Frontiers in Materials</a> </i> &nbsp;
In this paper, NiCrAlY coating was prepared by atmospheric plasma spraying (APS), and the influence of heat treatment on the mechanical property, tribological property, and oxidation resistance property of coating was researched. The coating was heat-treated at 900 and 1,100 • C, respectively. The microstructure of coating became more homogeneous after heat treatment. Meanwhile, heat treatment could effectively increase the microhardness and adhesive strength as well as decrease the porosity of
more &raquo; ... coating. The coating presented the highest adhesive strength of 62.1 MPa and the lowest porosity of 3.06%, as well as excellent tribological property and oxidation resistance property at 900 • C after 1,100 • C heat treatment.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fmats.2019.00067">doi:10.3389/fmats.2019.00067</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/o2zulgz7lbg6nguzhnrovyr7tq">fatcat:o2zulgz7lbg6nguzhnrovyr7tq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200209153221/https://fjfsdata01prod.blob.core.windows.net/articles/files/451384/pubmed-zip/.versions/2/.package-entries/fmats-06-00067-r1/fmats-06-00067.pdf?sv=2015-12-11&amp;sr=b&amp;sig=KeUKwrE2LnaMuHYKcL48%2BpOorQ2YQEPxIUAHHccMuSg%3D&amp;se=2020-02-09T15%3A32%3A51Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fmats-06-00067.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/b7/40/b740759e13878965a5f6c9a7a337be81e7f75a09.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fmats.2019.00067"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a>

Heat transfer performance and bundle-depth effect in horizontal-tube falling film evaporators

Shengqiang Shen, Gangtao Liang, Yali Guo, Rui Liu, Xingsen Mu
<span title="">2013</span> <i title="Informa UK Limited"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/lgnszrvvzjetlchxjabhpksvkm" style="color: black;">Desalination and Water Treatment</a> </i> &nbsp;
A set of experimental facilities were set up to measure overall heat transfer coefficient of horizontal-tube falling film evaporator with square-pitch bundle. Effect of spray density, saturation temperature, total temperature difference, and inlet steam velocity on the overall heat transfer coefficient K is studied. The tubes are made of HAL77-2A aluminum brass with an outer diameter of 25.4 mm. Fluids inside and outside the tubes are steam and fresh water respectively. The results indicate
more &raquo; ... growth of spray density and saturation temperature helps to increase the K. The K could also be increased by reducing the total temperature difference. However, the impact of the inlet steam velocity on the K is less significant. Furthermore tube bundle-depth effect and space distribution of local overall heat transfer coefficient K in the evaporator are also presented. Based on this investigation, basic engineering design information will be provided to establish the governing parameters for horizontal-tube falling film evaporator in the field of seawater desalination.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1080/19443994.2012.699349">doi:10.1080/19443994.2012.699349</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/p3euaytnuncfpnjyh2l7tdbvre">fatcat:p3euaytnuncfpnjyh2l7tdbvre</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170814110018/http://www.deswater.com/DWT_abstracts/vol_51_4-6/51_4-6_2013_830.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/a4/68/a4688c33680a42ef980af805226a188b6b6b3825.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1080/19443994.2012.699349"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> tandfonline.com </button> </a>

De novo Transcriptome Analysis of Miscanthus lutarioriparius Identifies Candidate Genes in Rhizome Development

Ruibo Hu, Changjiang Yu, Xiaoyu Wang, Chunlin Jia, Shengqiang Pei, Kang He, Guo He, Yingzhen Kong, Gongke Zhou
<span title="2017-04-12">2017</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/bbmitkj3efgeppizzjrx6w5emu" style="color: black;">Frontiers in Plant Science</a> </i> &nbsp;
HIGHLIGHT • De novo transcriptome profiling of five tissues reveals candidate genes putatively involved in rhizome development in M. lutarioriparius. Miscanthus lutarioriparius is a promising lignocellulosic feedstock for second-generation bioethanol production. However, the genomic resource for this species is relatively limited thus hampers our understanding of the molecular mechanisms underlying many important biological processes. In this study, we performed the first de novo transcriptome
more &raquo; ... nalysis of five tissues (leaf, stem, root, lateral bud and rhizome bud) of M. lutarioriparius with an emphasis to identify putative genes involved in rhizome development. Approximately 66 gigabase (GB) paired-end clean reads were obtained and assembled into 169,064 unigenes with an average length of 759 bp. Among these unigenes, 103,899 (61.5%) were annotated in seven public protein databases. Differential gene expression profiling analysis revealed that 4,609, 3,188, 1,679, 1,218, and 1,077 genes were predominantly expressed in root, leaf, stem, lateral bud, and rhizome bud, respectively. Their expression patterns were further classified into 12 distinct clusters. Pathway enrichment analysis revealed that genes predominantly expressed in rhizome bud were mainly involved in primary metabolism and hormone signaling and transduction pathways. Noteworthy, 19 transcription factors (TFs) and 16 hormone signaling pathwayrelated genes were identified to be predominantly expressed in rhizome bud compared with the other tissues, suggesting putative roles in rhizome formation and development. In addition, a predictive regulatory network was constructed between four TFs and six auxin and abscisic acid (ABA) -related genes. Furthermore, the expression of 24 rhizome-specific genes was further validated by quantitative real-time RT-PCR (qRT-PCR) analysis. Taken together, this study provide a global portrait of gene expression across five different tissues and reveal preliminary insights into rhizome growth and development. The data presented will contribute to our understanding of the molecular mechanisms underlying rhizome development in M. lutarioriparius and remarkably enrich the genomic resources of Miscanthus.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fpls.2017.00492">doi:10.3389/fpls.2017.00492</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28446913">pmid:28446913</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5388781/">pmcid:PMC5388781</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/xesm3qdfqnhlhpwegolo7ubf5q">fatcat:xesm3qdfqnhlhpwegolo7ubf5q</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20191112015620/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5388781&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/0d/d4/0dd404b81fb2032c4e7c7ad2537da6c27d084246.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fpls.2017.00492"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> frontiersin.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388781" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

High stretchability, strength and toughness of living cells enabled by hyperelastic vimentin network [article]

Jiliang Hu, Yiwei Li, Yukun Hao, Tianqi Zheng, German Alberto Parada, Huayin Wu, Shaoting Lin, Shida Wang, Xuanhe Zhao, Robert D. Goldman, Shengqiang Cai, Ming Guo
<span title="2018-10-17">2018</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Ronceray and the Guo Laboratory for helpful discussions. M. G. would like to acknowledge the support from the Department of Mechanical Engineering at MIT.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/446666">doi:10.1101/446666</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/utlqa4enw5fhdcbsqij55qwihu">fatcat:utlqa4enw5fhdcbsqij55qwihu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200325021210/https://www.biorxiv.org/content/biorxiv/early/2018/10/17/446666.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/a0/8e/a08e90a94dc9c78613219ec7b6588cf170c96a85.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/446666"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

SLR-superscaffolder: a de novo scaffolding tool for synthetic long reads using a top-to-bottom scheme [article]

Li Deng, Lidong Guo, Mengyang Xu, Wenchao Wang, Shengqiang Gu, Xia Zhao, Fang Chen, Ou Wang, Xun Xu, Guangyi Fan, Xin Liu
<span title="2019-09-08">2019</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
Synthetic long read (SLR) sequencing technologies, such as stLFR co-barcoded reads and 10X genomics linked-reads, have recently been developed and widely applied in genomics research. Here, we developed the SLR-superscaffolder, a standalone scaffolding tool for general synthetic long reads, with a top-to-bottom scheme where long fragment reads information is firstly used in large-scale scaffolding and followed by the paired-end information used in local scaffolding, to effectively use the SLR
more &raquo; ... formation. We tested SLR-superscaffolder power to assemble the human genome from three data resources. For instance, using the draft assembly with contig NG50 of 13 kb generated from 64-fold stLFR co-barcoded reads, SLR-superscaffolder significantly improved its scaffold NG50 to 15 Mb. Based on the draft assembly with scaffold NG50 of 58kb using 20-fold PCR-free NGS data, its scaffold NG50 was also drastically increased to 8 Mb. For the draft assembly with contig NG50 of 6.6 Mb from about 30-fold Oxford Nanopore long reads, SLR-superscaffolder presented a notable improvement in scaffold polishing with a scaffold NG50 of 21 Mb. Furthermore, comparing with other available SLR scaffolding tools, SLR-superscaffolder could produce an assembly with the highest quality of the longest contiguity and the least errors. Thanks to the valuable long-range information provided by SLR, SLR-superscaffolder shows a broad range of applications in the genome assembly. The source code is accessible on GitHub (https://github.com/BGI-Qingdao/SLR-superscaffolder).
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/762385">doi:10.1101/762385</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/n63dxrzf2nhldmojh43t5n4jbq">fatcat:n63dxrzf2nhldmojh43t5n4jbq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200310210956/https://www.biorxiv.org/content/biorxiv/early/2019/09/08/762385.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/8f/b6/8fb658434a47804ad00a8ea34903506ee989de30.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/762385"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

TGS-GapCloser: fast and accurately passing through the Bermuda in large genome using error-prone third-generation long reads [article]

Mengyang Xu, Lidong Guo, Shengqiang Gu, Ou Wang, Rui Zhang, Guangyi Fan, Xun Xu, Li Deng, Xin Liu
<span title="2019-11-05">2019</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
The completeness and accuracy of genome assemblies determine the quality of subsequent bioinformatics analysis. Despite benefiting from the medium/long-range information of third-generation sequencing techniques, current gap-closing tools to enhance assemblies suffer multi-alignments and high error rates, resulting in huge time and money costs. We developed a software tool, TGS-GapCloser that uses the low depth (>=10X) single molecule sequencing long reads without any error correction to close
more &raquo; ... aps. The algorithm distinguishes gap regions from the alignments of long reads against original scaffolds, corrects only the candidate regions, and assigns the best sequences to each gap. We demonstrate that TGS-GapCloser improves the contig N50 value of draft assembly by 25-fold on average, updating above 90% gaps with 93.96% positive predictive value. Despite of high error rate of raw long reads, improved assemblies archive Q50 (99.999%) single-base accuracy with only 11.8% decrement to inputs. Besides it could complete more gaps, and is also ~29-fold faster than mainstream gap-closing tools. BUSCO analysis revealed that 3.4%-13.1% more expected genes were complete. TGS-GapCloser also shows its power to fill gaps for ultra large genome assembly of ginkgo (~12Gb) with 71.6% of gaps closed. The validation of inserted or merged gap sequences was conducted with NGS reads and reference genomes, respectively. The updated genome assemblies may promote the gene annotation, structure variant calling and thus improving the downstream analysis of ontogeny, phylogeny, and evolution.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/831248">doi:10.1101/831248</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/rypsmiazsrh3fg6ep4gosq2hcu">fatcat:rypsmiazsrh3fg6ep4gosq2hcu</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200711011551/https://www.biorxiv.org/content/biorxiv/early/2019/11/05/831248.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/6c/c0/6cc0c1d558998db993234744bc8423292a54cb64.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/831248"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>
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