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Variable morphology of coronary atherosclerosis: Characterization of atherosclerotic plaque and residual arterial lumen size and shape by epicardial echocardiography

David D. McPherson, Maryl R. Johnson, Nanette M. Alvarez, Neil B. Rewcastle, Steve M. Collins, Mark L. Armstrong, Robert A. kieso, Linda J. Thorpe, Melvin L. Marcus, Richard E. Kerber
1992 Journal of the American College of Cardiology  
Portions of the wall were High frequency epicardial echocardiography is a technique that can directly evaluate coronary artery wall and lumen geometry in vivo at the time of cardiac surgery (Fig. 1 ).  ...  Other methods are needed for more precise in vivo assessment and delineation of atherosclerotic disease, complementing ex vivo pathologic studies that have shown that atherosclerosis has variable effects  ...  We further acknowledge the assistance of Marge Megan in histologic evaluation and Jean Waller for expert secretarial assistance.  ... 
doi:10.1016/s0735-1097(10)80278-5 pmid:1538015 fatcat:qsrjo6mrkjbjjjdwd655lzvxqy

Quantitative coronary angiography to measure progression and regression of coronary atherosclerosis. Value, limitations, and implications for clinical trials

P J de Feyter, P W Serruys, M J Davies, P Richardson, J Lubsen, M F Oliver
1991 Circulation  
cholesterol levels by diet.6 Very recently, three trials showed, using repeated coronary angiography, that cholesterol lowering was associated with less progression of coronary artery disease and that  ...  For instance, the Oslo Heart Study showed an impressive reduction in CHD morbidity and mortality in previously healthy men with the combined interventions of reducing cigarette smoking and lowering serum  ...  Sprenger de Rover for preparation of the manuscript.  ... 
doi:10.1161/01.cir.84.1.412 pmid:2060112 fatcat:x2yo4zfhrrh6na634zktndzx2q

A Three-Dimensional Quantification of Calcified and Non-calcified Plaque Based on Computed Tomography Coronary Angiography Images: Comparison with Virtual Histology Intravascular Ultrasound

Vassiliki Kigka, Antonis Sakellarios, George Rigas, Panagiota Tsompou, Ioannis Andrikos, Lampros Michalis, Dimitrios Fotiadis
2019 Zenodo  
The identification, quantification and characterization of coronary atherosclerotic plaque has a major influence on diagnosis and treatment of coronary artery disease (CAD).  ...  In this study, we present a novel methodology for the identification of the plaque burden of the coronary artery and the volumetric quantification of calcified plaques (CP) and non-calcified plaques (NCP  ...  Acknowledgements This work is partially funded by the European Commission: Project SMARTOOL, "Simulation Modeling of coronary ARTery disease: a tool for clinical decision support -SMARTool" GA number:  ... 
doi:10.5281/zenodo.3346585 fatcat:o2dnmocn2zgj5edzydjk7tj7aa

Automated Coronary Artery Atherosclerosis Detection and Weakly Supervised Localization on Coronary CT Angiography with a Deep 3-Dimensional Convolutional Neural Network [article]

Sema Candemir, Richard D. White, Mutlu Demirer, Vikash Gupta, Matthew T. Bigelow, Luciano M. Prevedello, Barbaros S. Erdal
2020 arXiv   pre-print
A 3-Dimensional Convolutional Neural Network (3D CNN) is utilized to model pathological changes (e.g., atherosclerotic plaques) in coronary vessels.  ...  absence of coronary artery atherosclerosis.  ...  We thank the anonymous reviewers for their suggestions that have helped to improve the quality of the manuscript.  ... 
arXiv:1911.13219v2 fatcat:ib7hkpsborfatagmtxmof3zkwu

Review. Automatic Segmentation Techniques of the Coronary Artery Using CT Images in Acute Coronary Syndromes

Sándor Miklós Szilágyi, Monica Marton Popovici, László Szilágyi
2017 Journal of Cardiovascular Emergencies  
This paper presents the main characteristics of plaque vulnerability, the role of CCTA in the assessment of vulnerable plaques, and automatic segmentation techniques of the coronary artery tree based on  ...  Coronary artery disease represents one of the leading reasons of death worldwide, and acute coronary syndromes are their most devastating consequences.  ...  and patient management, for the decision-making process and prognosis assessment of patients with coronary artery disease, all in a noninvasive stand-alone procedure. 55,115-117 The noninvasive visualization  ... 
doi:10.1515/jce-2017-0002 fatcat:ljakqyviwbcsraxdiscqljubqu

Machine Learning for Assessment of Coronary Artery Disease in Cardiac CT: A Survey

Nils Hampe, Jelmer M Wolterink, Sanne G M van Velzen, Tim Leiner, Ivana Išgum
2019 Frontiers in Cardiovascular Medicine  
In this mini review, we present a survey of the literature on ML-based analysis of coronary artery disease in cardiac CT.  ...  We summarize ML methods for detection and characterization of atherosclerotic plaque as well as anatomically and functionally significant coronary artery stenosis.  ...  INTRODUCTION Diagnosis and monitoring of coronary artery disease (CAD) is increasingly based on non-invasive imaging with computed tomography (CT), allowing excellent visualization of the coronary arteries  ... 
doi:10.3389/fcvm.2019.00172 pmid:32039237 pmcid:PMC6988816 fatcat:tsq6vf3vi5a4rjxoxzqy7xd5tu

Automated Coronary Artery Atherosclerosis Detection and Weakly Supervised Localization on Coronary CT Angiography with a Deep 3-Dimensional Convolutional Neural Network

Sema Candemir, Richard D. White, Mutlu Demirer, Vikash Gupta, Matthew T. Bigelow, Luciano M. Prevedello, Barbaros S. Erdal
2020 Computerized Medical Imaging and Graphics  
A 3-dimensional convolutional neural network (3D-CNN) is utilized to model pathological changes (e.g., atherosclerotic plaques) in coronary vessels.  ...  absence of coronary artery atherosclerosis.  ...  We thank the anonymous reviewers for their suggestions that have helped to improve the quality of the manuscript. Conflict of interest: None declared.  ... 
doi:10.1016/j.compmedimag.2020.101721 pmid:32470854 fatcat:wvfepvki7fbfvl56ixsvrfcwre

Consistency in Geometry Among Coronary Atherosclerotic Plaques Extracted From Computed Tomography Angiography

Haipeng Liu, Aleksandra Wingert, Xinhong Wang, Jucheng Zhang, Jianzhong Sun, Fei Chen, Syed Ghufran Khalid, Yinglan Gong, Ling Xia, Jun Jiang, Jian'an Wang, Dingchang Zheng
2021 Frontiers in Physiology  
The three-dimensional (3D) geometry of coronary atherosclerotic plaques is associated with plaque growth and the occurrence of coronary artery disease.  ...  In the proposed models, the exponents in the power functions of geometric parameters were in accordance with the fitted values.Conclusion: In patients with coronary artery disease, coronary plaques and  ...  ACKNOWLEDGMENTS We acknowledge the Medical Technology Research Centre of Anglia Ruskin University for their kind support.  ... 
doi:10.3389/fphys.2021.715265 pmid:34712147 pmcid:PMC8546263 fatcat:bouqtyyjjndk7fvygi5phloku4

Novel clinical applications of state-of-the-art multi-slice computed tomography

J. D. Schuijf, V. Delgado, J. M. van Werkhoven, F. R. de Graaf, J. E. van Velzen, M. M. Boogers, L. J. Kroft, A. de Roos, J. W. Jukema, J. H. C. Reiber, E. E. van der Wall, J. J. Bax
2009 The International Journal of Cardiovascular Imaging  
Indeed, a particular advantage of the technique is that in addition to evaluation of the coronary arteries it also allows assessment of cardiac structures and function.  ...  Conceivably, these advancements may allow further expansion of the use of MSCT beyond the visual assessment of the presence or absence of significant coronary artery disease.  ...  In 55 patients, all coronary artery segments (825 segments, based on a 15 segment model) could be visualized and subsequently quantified on MSCT.  ... 
doi:10.1007/s10554-009-9422-9 fatcat:2cpwkk4elbagfidmdyvq3hlok4

Recent Trends in Artificial Intelligence-Assisted Coronary Atherosclerotic Plaque Characterization

Anjan Gudigar, Sneha Nayak, Jyothi Samanth, U Raghavendra, Ashwal A J, Prabal Datta Barua, Md Nazmul Hasan, Edward J. Ciaccio, Ru-San Tan, U. Rajendra Acharya
2021 International Journal of Environmental Research and Public Health  
Coronary artery disease is a major cause of morbidity and mortality worldwide.  ...  A total of 122 publications were selected for evaluation and the analysis was summarized in terms of data sources, methods—machine versus deep learning—and performance metrics.  ...  Acknowledgments: The authors would like to thank the Manipal Academy of Higher Education (MAHE) for providing the required facility to carry out this research.  ... 
doi:10.3390/ijerph181910003 pmid:34639303 fatcat:eo6xdqukbfhwzkhydkfrmxohkq

Role of Non-Invasive CT Angiography in Improving Risk Stratification for Patients with Coronary Artery Diseases: A Retrospective Study

Mousa Q Hussein, Qays A Hassan, Husain M Abdullateef
2017 Prensa Medica Argentina  
Coronary computed tomography angiography (CCTA) has become an effective tool for noninvasive evaluation of coronary artery plaque characteristics.  ...  The objective of this study was to identify both "culprit" and "stable" coronary lesions by CCTA, aiming to improve risk stratification in patients who had coronary artery disease (CAD).  ...  Presence and composition of coronary atherosclerotic plaque The cross-sectional image at the site of biggest luminal narrowing was evaluated for the presence of atherosclerotic plaque.  ... 
doi:10.4172/lpma.1000265 fatcat:myfiggdxpvhafah5bbc4t4pyaa

Three-dimensional reconstruction of coronary arteries based on the integration of intravascular ultrasound and conventional angiography

Cristiano Guedes Bezerra, Gonzalo Daniel Maso Talou, Carlos Alberto Bulant, Breno de Alencar Araripe Falcão, José Mariani, Pablo Javier Blanco, Raúl Antonino Feijóo, Pedro Alves Lemos Neto
2015 Revista Brasileira de Cardiologia Invasiva (English Edition)  
vessel and overall visualization of key aspects of atherosclerotic disease, such as plaque remodeling and distribution.  ...  Methods: This study used angiography and intravascular ultrasound examinations already performed by clinical indication in individuals with known or suspected stable coronary artery disease.  ...  However, in the vessel in question, this model allows for visualization of coronary atherosclerotic disease in a more accurate way, through the precise location of the lesion and of plaque distribution  ... 
doi:10.1016/j.rbciev.2015.12.013 fatcat:lb4r6zk7ozadxpmiatj7xho2wi

Noninvasive definition of anatomic coronary artery disease by ultrafast computed tomographic scanning: A quantitative pathologic comparison study

D.Brent Simons, Robert S. Schwartz, William D. Edwards, Patrick F. Sheedy, Jerome F. Breen, John A. Rumberger
1992 Journal of the American College of Cardiology  
Coronary artery disease is a leading cause of mortality and morbidity in industrialized nations.  ...  Each epicardial artery was sectioned longitudinally, stained and measured with a planimeter for quantification of cross-sectional and atherosclerotic plaque areas at 3-mm intervals, corresponding to the  ...  We sincerely thank Allen Camrud, RN for expert assistance with handling and sampling of the histologic data, the technologists who patiently facilitated the ultrafast computed tomographic scanning in an  ... 
doi:10.1016/0735-1097(92)90367-v pmid:1401612 fatcat:s45atjutl5gtvfe26xyebbk5ni

Imaging of atherosclerosis: magnetic resonance imaging

R. Corti, V. Fuster
2011 European Heart Journal  
the extent of atherosclerotic disease and have high predictive values for future clinical events.  ...  Magnetic resonance imaging also allows for the detection of arterial thrombi and in defining thrombus age.  ...  Imaging of atherosclerosis The assessment of atherosclerotic plaque burden by non-invasive imaging techniques should allow for early detection of the disease and in vivo identification of high-risk plaques  ... 
doi:10.1093/eurheartj/ehr068 pmid:21508002 fatcat:xejthx5qwnckdhmkhs5knssoti

Coronary atherosclerotic wall thickening and vascular reactivity in humans. Elevated high-density lipoprotein levels ameliorate abnormal vasoconstriction in early atherosclerosis

A M Zeiher, V Schächlinger, S H Hohnloser, B Saurbier, H Just
1994 Circulation  
The response of coronary artery segments to acetylcholine varied from 35% dilation to 52% constriction and demonstrated a segmental pattern, with dilation and constriction observed in different segments  ...  Methods and Results In 26 patients without focal stenoses in the left anterior descending coronary artery, acetylcholine (0.036 to 3.6 ,g/mL) was infused into the artery to evaluate endothelium-mediated  ...  Acknowledgment We thank Werner Vach, PhD, Institute for Biomedical Statistics, University of Freiburg, for very helpful statistical advice.  ... 
doi:10.1161/01.cir.89.6.2525 pmid:8205660 fatcat:u2jwwsh4xzhplm346dibntop3a
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