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Quantitative vertebral morphometry using neighbor-conditional shape models

Marleen de Bruijne, Michael T. Lund, László B. Tankó, Paola C. Pettersen, Mads Nielsen
2007 Medical Image Analysis  
A novel method for vertebral fracture quantification from X-ray images is presented.  ...  Using pairwise conditional shape models trained on a set of healthy spines, the most likely normal vertebra shapes are estimated conditional on the shapes of all other vertebrae in the image.  ...  Vertebral fracture quantification Using the methods of the previous section, we propose the following procedure for fracture quantification from segmented spine images: (1) Construct models of individual  ... 
doi:10.1016/ pmid:17720611 fatcat:ihqbhclnrncwfmdktq7hrsc5me

Quantitative Vertebral Morphometry Using Neighbor-Conditional Shape Models [chapter]

Marleen de Bruijne, Michael T. Lund, László B. Tankó, Paola P. Pettersen, Mads Nielsen
2006 Lecture Notes in Computer Science  
A novel method for vertebral fracture quantification from X-ray images is presented.  ...  Using pairwise conditional shape models trained on a set of healthy spines, the most likely normal vertebra shapes are estimated conditional on the shapes of all other vertebrae in the image.  ...  Vertebral fracture quantification Using the methods of the previous section, we propose the following procedure for fracture quantification from segmented spine images: (1) Construct models of individual  ... 
doi:10.1007/11866565_1 fatcat:2a4cbpzaozdxpnzm4apkhnt7yu

Unraveling the Role of Structure and Density in Determining Vertebral Bone Strength

J. F. Veenland, T. M. Link, W. Konermann, N. Meier, J. L. Grashuis, E. S. Gelsema
1997 Calcified Tissue International  
Therefore, quantification of the structure in radiographs by texture parameters may result in a better prediction of fracture risk.  ...  Multiple regression analysis showed that in female vertebrae, the addition of one texture parameter to BMD results in a better prediction of strength.  ...  The correlation with both fracture stress and BMD was higher for the female vertebrae than for the male vertebrae.  ... 
doi:10.1007/s002239900370 pmid:9383274 fatcat:q2m77l3emfbzvcb7rjmvequyni

Probabilistic Point Cloud Reconstructions for Vertebral Shape Analysis [article]

Anjany Sekuboyina, Markus Rempfler, Alexander Valentinitsch, Maximilian Loeffler, Jan S. Kirschke, Bjoern H. Menze
2019 arXiv   pre-print
We propose an auto-encoding network architecture for point clouds (PC) capable of extracting shape signatures without supervision.  ...  By learning to efficiently reconstruct only healthy vertebrae, fractures are detected as anomalous reconstructions.  ...  The Quadro P5000 used for this work was donated by NVIDIA Corporation.  ... 
arXiv:1907.09254v2 fatcat:pqbjp44zi5bnxciz4luowu5oem

A Localisation-Segmentation Approach for Multi-label Annotation of Lumbar Vertebrae using Deep Nets [article]

Anjany Sekuboyina, Alexander Valentinitsch, Jan S. Kirschke, and Bjoern H. Menze
2017 arXiv   pre-print
The first stage employs a multi-layered perceptron performing non-linear regression for locating the lumbar region using the global context.  ...  Aided with practical data augmentation for training, our approach is highly generalisable, capable of successfully segmenting both healthy and abnormal vertebrae (fractured and scoliotic spines).  ...  It is obvious that such models cannot generalise to a fractured vertebra or a deformed spine.  ... 
arXiv:1703.04347v1 fatcat:i4ad5vikpnhdjpoyekqrfr76nq

Evaluation of a new approach to compute intervertebral disc height measurements from lateral radiographic views of the spine

Brett T. Allaire, M. Clara DePaolis Kaluza, Alexander G. Bruno, Elizabeth J. Samelson, Douglas P. Kiel, Dennis E. Anderson, Mary L. Bouxsein
2016 European spine journal  
Conclusions-Using our modified DCRA algorithm, it is not necessary to exclude vertebrae with fracture or other deformity from disc height measurements as in the standard DCRA.  ...  Thus, we developed and tested a modified DCRA algorithm that does not depend on vertebral shape.  ...  eliminates the need to exclude fractured or deformed vertebrae.  ... 
doi:10.1007/s00586-016-4817-5 pmid:27757680 pmcid:PMC5350627 fatcat:2wxirkxiwzbalk57hnga26ed64

Vertebral deformities and fractures are associated with MRI and pQCT measures obtained at the distal tibia and radius of postmenopausal women

C. S. Rajapakse, E. A. Phillips, W. Sun, M. J. Wald, J. F. Magland, P. J. Snyder, F. W. Wehrli
2013 Osteoporosis International  
Introduction-Prevalent vertebral deformities and fractures are known to predict incident further fractures.  ...  Results-Several distal extremity MRI and pQCT measures showed negative association with vertebral deformity on the basis of single parameter correlation (r up to 0.67) and two-parameter regression (r up  ...  Most vertebral fractures are asymptomatic [3, 20, 21] , which are consequences of gradual changes in the vertebral shape.  ... 
doi:10.1007/s00198-013-2569-1 pmid:24221453 pmcid:PMC4746757 fatcat:ieba2hpnfzfzhlurrmv56jbj7y

A comparison of three methods for measuring thoracic kyphosis: implications for clinical studies

S. Goh, R. I. Price, P. J. Leedman, K. P. Singer
2000 Rheumatology  
Regression models were applied for agreement analyses, and to examine the relative contribution of vertebral body and disc shape on the extent of curvature. Results and conclusions.  ...  Strong associations existed between curvature and angle data derived from the three methods, confirming the clinical utility of these techniques for the quantification of thoracic kyphosis.  ...  the quantification of shape parameters [24] .  ... 
doi:10.1093/rheumatology/39.3.310 pmid:10788541 fatcat:nbldcitsujahxox2n5wa5omila

Detection of osteoporosis in lumbar spine [L1-L4] trabecular bone: a review article

Kavita Avinash Patil, K. V. Mahendra Prashanth, A. Ramalingaiah
2021 International Journal of Research in Orthopaedics  
It largely causes mild bone fractures and further stages lead to the demise of an individual.  ...  The detection of osteoporosis in lumbar spine has been widely recognized as a promising way to frequent fractures.  ...  Contours of vertebrae are also analyzed on the basis of texture and shape features.  ... 
doi:10.18203/issn.2455-4510.intjresorthop20212440 fatcat:wtozgatbxfhpjeedip4xprjihq

In vivo quantification of bone mineral density of lumbar vertebrae using fast kVp switching dual-energy CT: correlation with quantitative computed tomography

Shuwei Zhou, Lu Zhu, Tian You, Ping Li, Hongrong Shen, Yewen He, Hui Gao, Luyou Yan, Zhuo He, Ying Guo, Yaxi Zhang, Kun Zhang
2021 Quantitative Imaging in Medicine and Surgery  
DCa(Fat) and DHAP(Fat) showed relatively similar and optimal predictive capability for QCT-derived BMD (both: adjusted R2 =0.987, NMSE =1.6%, RElinear =0.6%).  ...  This study aimed to evaluate the feasibility and accuracy of phantomless in vivo DECT-based BMD quantification in comparison with QCT.  ...  in the vertebrae more accurately than DXA, but also predicts incident vertebral fractures more accurately than DXA (11) (12) (13) .  ... 
doi:10.21037/qims-20-367 pmid:33392033 pmcid:PMC7719923 fatcat:sfkywxabfvh2pm55rxb4m3bvde

Bone mineral density assessment using iterative reconstruction compared with quantitative computed tomography as the standard of reference

Constanze Mann, Katharina Ziegeler, Jürgen Mews, Martina Plaschke, Ahi Sema Issever
2018 Scientific Reports  
CTDIvol were 7.50, 5.00, 6.82 (±2.03) and 1.72 (±0.50) mGy for protocols 1, 2, 3 and 4 respectively. Objective image quality was highest for protocol 4.  ...  The use of IR for BMD assessment significantly lowers radiation exposure compared to standard QCT and protocols with FBP while not degrading BMD measurement.  ...  Here only the BMD value is of interest no volume information from the vertebrae i.e. for fracture analysis.  ... 
doi:10.1038/s41598-018-33444-5 pmid:30305658 pmcid:PMC6179993 fatcat:kkzwur4yyzebvjb63c5xatfjau

Biomechanical tolerance of whole lumbar spines in straightened posture subjected to axial acceleration

Brian D. Stemper, Sajal Chirvi, Ninh Doan, Jamie L. Baisden, Dennis J. Maiman, William H. Curry, Narayan Yoganandan, Frank A. Pintar, Glenn Paskoff, Barry S. Shender
2017 Journal of Orthopaedic Research  
Quantification of biomechanical tolerance is necessary for injury prediction and protection of vehicular occupants.  ...  In general, force-based tolerance was consistent with previous shorter-segment lumbar spine testing (3-5 vertebrae), although studies incorporating isolated vertebral bodies reported higher tolerance attributable  ...  vertebrae, and between specimens that sustained fracture at L1 only versus any other level.  ... 
doi:10.1002/jor.23826 pmid:29194745 fatcat:xwerddkc6zb5taznqkynnqsg6q

Spinal vertebrae localization and analysis on disproportionality in curvature using radiography—a comprehensive review

Joddat Fatima, Muhammad Usman Akram, Amina Jameel, Adeel Muzaffar Syed
2021 EURASIP Journal on Image and Video Processing  
Existing methods do not handle the illumination changes and shape-based variations. The low-contrast and unclear view of the vertebrae also makes it difficult to get good results.  ...  of curvature deformity of the vertebrae in the spinal cord.  ...  Detection procedure was based on random regression forest (RRF) for localization and identification of the vertebrae. Voxel-wise operations are applied for the improvement in results.  ... 
doi:10.1186/s13640-021-00563-5 fatcat:khzxpnubxjdnto4zdcpbxqxvnu

Opportunistic osteoporosis screening in multi-detector CT images via local classification of textures

A. Valentinitsch, S. Trebeschi, J. Kaesmacher, C. Lorenz, M. T. Löffler, C. Zimmer, T. Baum, J. S. Kirschke
2019 Osteoporosis International  
Our study proposed an automatic pipeline for opportunistic osteoporosis screening using 3D texture features and regional vBMD using multi-detector CT images.  ...  A combination of different local and global texture features outperformed the global vBMD and showed high discriminative power to identify patients with vertebral fractures.  ...  This suggests that as many vertebrae as possible should be included for an optimal prediction of the individual fracture risk.  ... 
doi:10.1007/s00198-019-04910-1 pmid:30830261 pmcid:PMC6546649 fatcat:cjrmoaxnlra2pjnacoaoeymldu

Association of MRS-Based Vertebral Bone Marrow Fat Fraction with Bone Strength in a Human In Vitro Model

Dimitrios C. Karampinos, Stefan Ruschke, Olga Gordijenko, Eduardo Grande Garcia, Hendrik Kooijman, Rainer Burgkart, Ernst J. Rummeny, Jan S. Bauer, Thomas Baum
2015 Journal of Osteoporosis  
In this study, ten vertebrae were harvested from fresh human cadavers. Trabecular BMD and microstructure parameters were extracted from MDCT.  ...  for prediction of fracture risk.  ...  in vivo bone marrow fat quantification as recently shown in the proximal femur and spine [28, 34] .  ... 
doi:10.1155/2015/152349 pmid:25969766 pmcid:PMC4417596 fatcat:adrwzpszbjglvjczao6i5jixcy
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