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Characteristics and Predictors of Drug-Eluting Stent Thrombosis

Kyung Woo Park, Seok-Jae Hwang, Dong-A Kwon, Byung-Hee Oh, Young-Bae Park, In-Ho Chae, Hyeon-Cheol Gwon, Seung-Jung Park, Ki Bae Seung, Taehoon Ahn, Jung-Han Yoon, Yang-Soo Jang (+4 others)
2011 Circulation Journal  
PARK KW et al.  ... 
doi:10.1253/circj.cj-10-1160 pmid:21628837 fatcat:oxkqnehk7zeulioivfi2ro4mq4

Characterization of sporulation histidine kinases of Paenibacillus polymyxa

Soo-Young Park, Seung-Hwan Park, Soo-Keun Choi
2012 Research in Microbiology  
Park et al. / Research in Microbiology 163 (2012) 272e278  ... 
doi:10.1016/j.resmic.2012.02.003 pmid:22391390 fatcat:gmuumbaktzf73heyo3gqwnxrk4

Everolimus-Eluting Stent Implantation for Unprotected Left Main Coronary Artery Stenosis

Young-Hak Kim, Duk-Woo Park, Jung-Min Ahn, Sung-Cheol Yun, Hae Geun Song, Jong-Young Lee, Won-Jang Kim, Soo-Jin Kang, Seung-Whan Lee, Cheol Whan Lee, Seong-Wook Park, Yangsoo Jang (+9 others)
2012 JACC: Cardiovascular Interventions  
J A C C : C A R D I O V A S C U L A R I N T E R V E N T I O N S , V O L . 5 , N O . 7 , 2 0 1 2 Kim et al. J U L Y 2 0 1 2 : 7 0 8 -1 7 Everolimus Stent for Left Main Stenosis TVR ‫؍‬ target vessel revascularization ULMCA ‫؍‬ unprotected left main coronary artery J A C C : C A R D I O V A S C U L A R I N T E R V E N T I O N S , V O L . 5 , N O . 7 , 2 0 1 2 J U L Y 2 0 1 2 : 7 0 8 -1 7 Kim et al. Everolimus Stent for Left Main Stenosis Others 1 (0.9) 7 (8.0) Angiographic follow-up 249 (76.1)
more » ... (60.8) 51 (18.8) Ͻ0.001 Values are mean Ϯ SD or n (%). *p values for post-hoc comparisons: for multivessel disease, Ͻ0.001 between SES versus EES, 0.20 between SES versus CABG, and Ͻ0.001 between EES versus CABG; for bifurcation left main stenosis, 0.17 between SES versus EES, 0.074 between SES versus CABG, and 0.008 between EES versus CABG; and for SYNTAX score, Ͻ0.001 between SES versus EES, Ͻ0.001 between SES versus CABG, and Ͻ0.001 between EES versus CABG. EES patients were enrolled in the PRECOMBAT-2 study and SES and CABG patients in the historical controls of PRECOMBAT study. EES ϭ everolimus-eluting stent(s); CABG ϭ coronary artery bypass graft; MI ϭ myocardial infarction; PCI ϭ percutaneous coronary intervention; PRECOMBAT ϭ Premier of Randomized Comparison of Bypass Surgery versus Angioplasty Using Sirolimus-Eluting Stent in Patients with Left Main Coronary Artery Disease; PRECOMBAT-2 ϭ Premier of Randomized Comparison of Bypass Surgery versus Angioplasty Using Everolimus-Eluting Stent in Patients with Left Main Coronary Artery Disease-2; SES ϭ sirolimus-eluting stent(s). J A C C : C A R D I O V A S C U L A R I N T E R V E N T I O N S , V O L . 5 , N O . 7 , 2 0 1 2 Kim et al. J U L Y 2 0 1 2 : 7 0 8 -1 7 Everolimus Stent for Left Main Stenosis Values are n (%), as determined using the Kaplan-Meier method. p values were calculated using the log-rank test. *The p values for post hoc comparisons were 0.41 between SES versus EES, 0.005 between SES versus CABG, and 0.019 for EES versus CABG. EES patients were enrolled in the PRECOMBAT-2 study, and SES and CABG patients in the historical controls of PRECOMBAT study. MACCE ϭ major adverse cardiac or cerebrovascular event(s); TVR ϭ target vessel revascularization; other abbreviations as in Table 1 . J A C C : C A R D I O V A S C U L A R I N T E R V E N T I O N S , V O L . 5 , N O . 7 , 2 0 1 2 Kim et al. J U L Y 2 0 1 2 : 7 0 8 -1 7 Everolimus Stent for Left Main Stenosis 713 J A C C : C A R D I O V A S C U L A R I N T E R V E N T I O N S , V O L . 5 , N O . 7 , 2 0 1 2 J U L Y 2 0 1 2 : 7 0 8 -1 7 Kim et al. Everolimus Stent for Left Main Stenosis J A C C : C A R D I O V A S C U L A R I N T E R V E N T I O N S , V O L . 5 , N O . 7 , 2 0 1 2 J U L Y 2 0 1 2 : 7 0 8 -1 7 Kim et al. Everolimus Stent for Left Main Stenosis 716 Key Words: bypass surgery Ⅲ coronary disease Ⅲ left main coronary disease Ⅲ stents. To participate in this CME activity by taking the quiz and claiming your CME credit certificate, please go to http://interventions.onlinejacc.org/ and select the CME tab on the top navigation bar. J A C C : C A R D I O V A S C U L A R I N T E R V E N T I O N S , V O L . 5 , N O . 7 , 2 0 1 2 Kim et al. J U L Y 2 0 1 2 : 7 0 8 -1 7
doi:10.1016/j.jcin.2012.05.002 pmid:22814775 fatcat:rnkbh5k4drhrllakfc5mhz4dby

Long-Term Safety and Efficacy of Stenting Versus Coronary Artery Bypass Grafting for Unprotected Left Main Coronary Artery Disease

Duk-Woo Park, Ki Bae Seung, Young-Hak Kim, Jong-Young Lee, Won-Jang Kim, Soo-Jin Kang, Seung-Whan Lee, Cheol Whan Lee, Seong-Wook Park, Sung-Cheol Yun, Hyeon-Cheol Gwon, Myung-Ho Jeong (+10 others)
2010 Journal of the American College of Cardiology  
Key Words: coronary disease y revascularization y stents y surgery. 124 Park et al.  ...  DES ‫؍‬ drug-eluting stent(s) HR ‫؍‬ hazard ratio LMCA ‫؍‬ left main coronary artery MI ‫؍‬ myocardial infarction PCI ‫؍‬ percutaneous coronary intervention TVR ‫؍‬ target vessel revascularization 118 Park  ...  CI ϭ confidence interval; MI ϭ myocardial infarction; TVR ϭ target vessel revascularization; other abbreviations as in Table 1. 121 JACC Vol. 56, No. 2, 2010 Park et al.  ... 
doi:10.1016/j.jacc.2010.04.004 pmid:20451344 fatcat:5pgndjlkqnb3bnziokwiaqdoeu

Ventilation impairment of residents around a cement plant

Sul Ha Kim, Chul Gab Lee, Han Soo Song, Hyun Seung Lee, Min Soo Jung, Jae Yoon Kim, Choong Hee Park, Seung Chul Ahn, Seung Do Yu
2015 Annals of Occupational and Environmental Medicine  
Objectives: To identify adverse health effects due to air pollution derived from a cement plant in Korea. The ventilation impairment in residents around a cement plant was compared to another group through a pulmonary function test (PFT). Methods: From June to August of 2013, both a pre and post-bronchodilator PFT was conducted on a "more exposed group (MEG)" which consisted of 318 people who lived within a 1 km radius of a cement plant and a "less exposed group (LEG)" which consisted of 129
more » ... ple who lived more than 5 km away from the same plant. The largest forced expiratory volume in a one second (FEV1) reading and a functional residual capacity (FVC) reading were recorded after examining the data from all of the usable curves that were agreed upon as valid by PFT experts of committee of National Institute of Environmental Research. The global initiative for chronic obstructive lung disease (GOLD) criteria for COPD, defined the FEV1/FVC ratio < 0.7 as the obstructive type, and the FEV1/FVC ratio ≧ 0.7 and FVC% predicted < 80% were as the restrictive type. The FVC% predicted value was estimated using Korean equation. We compared the proportion of lung function impairments between the MEG and the LEG by using a chi-square, and estimated the OR of obstructive and restrictive ventilation impairments by logistic regression. Results: The obstructive type impairment proportion was 9.7% in the MEG, whereas it was 8.5% in the LEG. The restrictive type was 21.6% in the MEG which was more than the 12.4% of the LEG. The odds ratio (OR) of total ventilation impairment in the MEG was 2.63 (95% CI 1.50~4.61) compared to the LEG. The OR of obstructive type in the MEG was 1.60 (95% CI 0.70~3.65), the smoking history was 3.10 (CI 1.10~8.66) whereas OR of restrictive type in the MEG was 2.55 (95% CI 1.37~4.76), the smoking history was 0.75 (95% CI 0.35~1.60) after adjusting for sex and age. Level of exposure to particulate played a role in both types. However, it appeared to be a significant variable in restrictive type, while smoking history was also an important variable in obstructive type. Conclusion: Although this study is a limited cross-section study with a small number of subjects, ventilation impairment rate is higher in the MEG. There might be a possibility that it is due to long-term exposure to particulate dust generated by the cement plant.
doi:10.1186/s40557-014-0048-6 pmid:25713724 pmcid:PMC4338829 fatcat:hpowqogc35htbh6v4hdcqcwcva

Predictors for Functionally Significant In-Stent Restenosis

Soo-Jin Kang, Young-Rak Cho, Gyung-Min Park, Jung-Min Ahn, Seung-Bong Han, Jong-Young Lee, Won-Jang Kim, Duk-Woo Park, Seung-Whan Lee, Young-Hak Kim, Cheol Whan Lee, Seong-Wook Park (+2 others)
2013 JACC Cardiovascular Imaging  
O B J E C T I V E S The aim of this study was to assess the clinical and morphological predictors for functionally significant in-stent restenosis (ISR). B AC K G R O U N D Although they have been studied de novo in native coronary artery lesions, the relationships between clinical and morphological characteristics and the hemodynamic significance of ISR are not well understood. M E T H O D S In 175 patients with ISR of a single coronary artery (angiographic stenosis >50%), we compared
more » ... ive coronary angiography and intravascular ultrasound (IVUS) with stress myocardial single-photon emission computed tomography (SPECT). A positive SPECT was a reversible perfusion defect in the territory of the ISR artery. R E S U LT S Overall, 103 (59%) patients had a positive SPECT. In-segment IVUS minimal lumen area (MLA) was significantly smaller in lesions with positive SPECT compared with negative SPECT (1.7 AE 0.5 mm 2 vs. 2.4 AE 0.8 mm 2 , p < 0.001). Stent underexpansion (minimal stent area <5.0 mm 2 ) was more common in the positive SPECT group than in the negative SPECT group (52% vs. 32%, p ¼ 0.010). A positive SPECT was seen in 54% (65 of 121) of focal ISR lesions compared with 70% (38 of 54) of multifocal or diffuse ISR lesions as assessed by IVUS (p ¼ 0.039). Independent determinants for a positive SPECT were diabetes (odds ratio [OR]: 2.41; 95% confidence interval [CI]: 1.02 to 5.68; p ¼ 0.046), in-segment angiographic diameter stenosis (OR: 1.06; 95% CI: 1.03 to 1.09; p < 0.001), insegment IVUS-MLA (OR: 0.30; 95% CI: 0.14 to 0.63; p ¼ 0.001), stent underexpansion (minimal stent area <5.0 mm 2 ), (OR: 2.91; 95% CI: 1.19 to 7.07; p ¼ 0.019), proximal location of the IVUS-MLA (OR: 4.62; 95% CI: 1.75 to 12.18; p ¼ 0.002), and a multifocal or diffuse ISR pattern (OR: 2.50; 95% CI: 0.99 to 6.28; p ¼ 0.050). An in-segment angiographic diameter stenosis $69.5% (72% sensitivity, 74% specificity, area under the curve ¼ 0.793) and an IVUS-MLA #1.9 mm 2 (67% sensitivity, 75% specificity, area under the curve ¼ 0.756) best predicted a positive SPECT; however, the overall diagnostic accuracies were only 73% and 70%, respectively.
doi:10.1016/j.jcmg.2013.09.006 pmid:24229771 fatcat:hhtr725t5zhyxktjfmaha5tsbm

Usefulness of liquid-based preparation in urine cytology

Eu Chang Hwang, Seong Hoon Park, Seung Il Jung, Dong Deuk Kwon, Kwangsung Park, Soo Bang Ryu, Chang Soo Park
2007 International journal of urology  
Objective: ThinPrep (TP), a liquid-based cytological and non-invasive technique to confirm the diagnosis of bladder cancer, is reported to be a better screening test than the conventional cytospin method. This study compared the new MonoPrep2 (MP), a liquid-based cytological technique, with TP for diagnosing bladder cancer. , urine samples from 284 patients were processed using the TP and MP methods. The cytological diagnosis and the determination of specimen quality were performed separately.
more » ... he cytological diagnoses were classified into four categories: unsatisfactory, benign, borderline, and malignant. A subsequent biopsy was performed in 73 patients. The cytological diagnoses were compared with the biopsy results to evaluate the sensitivity and specificity of the two methods. Results: Considering all the features examined , the overall specimen quality was comparable between the MP and TP techniques in the majority of cases. The rate of satisfactory specimens was 100% for TP and 98.6% for MP. The diagnostic capacity was similar between MP and TP. The overall sensitivities with MP and TP were 58.6 and 62.0%, respectively, and the specificities were 100 and 97.7%; the differences were not significant (P > 0.05). Conclusions: MP and TP produced comparable results in diagnosing bladder cancer. As MP is less expensive than TP, we recommend MP as an alternative liquid-based cytology method for use in bladder cancer screening.
doi:10.1111/j.1442-2042.2006.01731.x pmid:17645607 fatcat:xuvmbnfik5d6hfx5p3lixt5gue

Duration of Dual Antiplatelet Therapy After Implantation of Drug-Eluting Stents

Seung-Jung Park, Duk-Woo Park, Young-Hak Kim, Soo-Jin Kang, Seung-Whan Lee, Cheol Whan Lee, Ki-Hoon Han, Seong-Wook Park, Sung-Cheol Yun, Sang-Gon Lee, Seung-Woon Rha, In-Whan Seong (+18 others)
2011 Survey of Anesthesiology  
Number of patients enrolled in final analysis 1,625 patients 1,076 patients Follow-up duration after randomization in months, median (interquartile range) 19.6 (12.3-25.5) 18.6 (14.2-21.9)
doi:10.1097/01.sa.0000391589.20506.f0 fatcat:4q2ewgfnzjbtdif5uooxi5jb6y

Atrial Mechanical Function After Maze Procedure for Atrial Fibrillation Concomitant With Mitral Valve Surgery

Bong Gun Song, Soo Jin Cho, Sang Yeub Lee, Jung Hyuk Kim, Seung Min Choi, Yong Hwan Park, Jin-Oh Choi, Sang-Chol Lee, Young Keun On, Seung Woo Park, June Soo Kim, PyoWon Park
2008 Korean Circulation Journal  
and Objectives: The maze procedure is effective in restoring sinus rhythm (SR) in patients with atrial fibrillation (AF). We compared the left atrial mechanical function (LAMF) of patients whose rhythm was converted to SR after maze procedure with that of patients whose rhythm was not converted to SR and determined if preoperative left atrial volume index (LAVI) and immediate postoperative LAMF could predict conversion of AF to SR. Subjects and Methods: We prospectively evaluated 80 patients
more » ... h AF treated with the maze procedure between March 2005 and February 2007. LAMF was assessed by looking at left atrial ejection volume (LAEV) and ejection fraction (LAEF) during echocardiography before, 2 weeks after, and 6 months after the procedure. Results: Of the 80 enrolled patients, 71 were converted to SR after the maze procedure (SR group), and 9 were not converted to SR (AF group). There were no significant differences in age, sex, hypertension, diabetes mellitus, renal failure, stroke, thyroid dysfunction, or smoking history between the groups. Pre-operative LAVI (p=0.010) was a predictor of conversion of AF to SR. LAEF gradually increased in the SR group during follow-up, but not in the AF group. Conclusion: LAMF recovered in the SR group after the maze procedure, irrespective of clinical presentation and initial LAMF. Preoperative LAVI predicted SR conversion. (Korean Circ J 2008;38:606-611)
doi:10.4070/kcj.2008.38.11.606 fatcat:r23yk5ucvzbdzj65feb3aldq5a

Thyroid dysfunction in patients with suspected or documented supraventricular tachyarrhythmia

Hye Bin Gwag, Ji Eun Jun, Youngjun Park, Seong Soo Lee, Seung-Jung Park, June Soo Kim, Kyoung-Min Park, Young Keun On
2019 International Journal of Arrhythmia  
Gwag HB and Park SJ contributed to data curation and formal analysis. Gwag HB, Park Y, and Lee SS contributed to investigation. On YK and Kim JS contributed to supervision.  ...  Gwag HB and Park SJ contributed to validation and visualization. Gwag HB contributed to writing-original draft. On YK and Park KM contributed to writing-review and editing.  ... 
doi:10.1186/s42444-019-0008-x fatcat:b2jtc6obcnbtjkhp3qxfm54mna

A Highly Efficient CRISPR-Cas9-Mediated Large Genomic Deletion in Bacillus subtilis

Younju So, Soo-Young Park, Eun-Hye Park, Seung-Hwan Park, Eui-Joong Kim, Jae-Gu Pan, Soo-Keun Choi
2017 Frontiers in Microbiology  
Copyright © 2017 So, Park, Park, Park, Kim, Pan and Choi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).  ... 
doi:10.3389/fmicb.2017.01167 pmid:28690606 pmcid:PMC5481315 fatcat:nzql4pmmszbh7iv77is5od4ikq

Reply

Seung-Jung Park, Soo-Jin Kang, Jung-Min Ahn
2015 JACC: Cardiovascular Interventions  
doi:10.1016/j.jcin.2014.11.006 pmid:25616831 fatcat:qaqdsbomgnhr5nqezga7ednpfu

Study of Pallet Scale Modified Atmosphere Packaging Films for Reducing Water Condensation

Jinse Kim, Jong Woo Park, Seokho Park, Dong Soo Choi, Seung Ryul Choi, Yong Hoon Kim, Soo Jang Lee, Chun Wan Park, Jung- Soo Lee, Byoung-Kwan Cho
2016 Journal of Biosystems Engineering  
The gas transmission rate of a film can be changed by the thickness and the perforation rates of the film (Park and Kang, 1998; Mistriotis et al., 2011) .  ... 
doi:10.5307/jbe.2016.41.2.098 fatcat:lq5ibhu2d5hffawdrygeav764q

Emphysema prevalence related air pollution caused by a cement plant

Hyun Seung Lee, Chul Gab Lee, Dong Hun Kim, Han Soo Song, Min Soo Jung, Jae Yoon Kim, Choong Hee Park, Seung Chul Ahn, Seung Do Yu
2016 Annals of Occupational and Environmental Medicine  
To identify adverse pulmonary health effects due to air pollution derived from a cement plant in Korea. The emphysema prevalence in residents around a cement plant was compared to that in the group who live far away from the plant by chest films (PA and lateral view) and high-resolution computed tomography (HRCT) lung images. Methods: From chest films and HRCT scan were conducted on residents over the age of 40 who lived around a cement plant. The residents were divided into two groups; a "more
more » ... exposed group (MEG)" which consisted of 1,046 people who lived within a 1 km radius and a "less exposed group (LEG)" which consisted of 317 people who lived more than 5 km away from the same plant. We compared the emphysema prevalence and estimated the OR of this between the MEG and the LEG by using a chi-square and logistic regression on chest films and HRCT. Results: The emphysema prevalence was 9.1 % in the LEG, 14.3 % in the MEG on chest films and 11.4 %, 17.8 % on the HRCT, respectively. The OR of the emphysema prevalence in MEG was 2.92 (95 % CI 1.77-4.83) on the chest films, 2.56 (95 % CI 1.64-3.99) on the HRCT after sex, age, body mass index (BMI), smoking history, residency period and firewood used history were adjusted. The OR in the less than 29 pack-years smoking history was 1.66 (95 % CI 0.92-3.06) and in the more than 30 pack-years was 3.05 (95 % CI 1.68-5.52) on the chest films, and was 1.68 (95 % CI 0.98-2.90), 2.93 (95 % CI 1.72-4.98) on the HRCT, respectively. Conclusion: The emphysema prevalence seems to be affected by the level of exposure to air pollution derived from the cement plant as well as sex, age, BMI, and smoking history in this study. Moreover, the OR of the case of the more exposed to the air pollution was similar to that of the case in smoking.
doi:10.1186/s40557-016-0101-8 pmid:27057315 pmcid:PMC4823915 fatcat:2xzvqp43zffv5b65zwrhjv4hum

Frequency and Clinical Associating Factors of Valvular Heart Disease in Asymptomatic Korean Adults

Min Sun Kim, Soo Jin Cho, Sung-Ji Park, Sung Won Cho, Soo-Hee Choi, Hye Seung Kim, Keumhee Carriere, Eun Kyoung Kim, Sung-A Chang, Sang-Chol Lee, Seung Woo Park
2019 Scientific Reports  
Limited information is available on the prevalence and clinical determinants of valvular heart disease (VHD) in apparently healthy people. This study sought to assess the frequency and clinical associating factors of aortic stenosis (AS), aortic regurgitation (AR), mitral stenosis (MS), mitral regurgitation (MR), tricuspid regurgitation (TR) in asymptomatic individuals with health check-up examination. We included 23,254 subjects ≥50 years of age who underwent a health check-up examination with
more » ... transthoracic echocardiography (TTE) between 2012 and 2016 in a single tertiary-care hospital in Korea. Among a total of 23,254 subjects, 15,358 men (66.0%) and 7,896 women (34.0%) underwent TTE. Newly identified (predominantly mild) VHD was detected in 9.4% of subjects. The most common VHD were TR (4.6%), AR (3.0%) and MR (2.4%). Clinically significant (more than moderate) VHD was identified in 176 subjects (0.8%). Age ≥75 years was associated with all clinically significant VHD, and female gender was associated with AR, MS and TR. Korea has been very active in the health check-up examination including echocardiography. We find that VHD in apparently healthy people is not uncommon than believed; all VHD except MS were more frequent in elderly over 75 years of age in a large population-based study.
doi:10.1038/s41598-019-53277-0 pmid:31727975 pmcid:PMC6856181 fatcat:puqinzd5hjgffj73a5jxrkruay
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