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Sequence Surveyor: Leveraging Overview for Scalable Genomic Alignment Visualization

D. Albers, C. Dewey, M. Gleicher
2011 IEEE Transactions on Visualization and Computer Graphics  
We present Sequence Surveyor, a prototype that embodies these ideas for scalable multiple whole-genome alignment overview visualization.  ...  Genome alignment visualization and, more generally, sequence alignment visualization are an important tool for understanding genomic sequence data.  ...  We have introduced Sequence Surveyor, a scalable genomic alignment overview visualization.  ... 
doi:10.1109/tvcg.2011.232 pmid:22034360 fatcat:dfjxofusijhd7dws33djune7ca

Visualization of Biological Data - Crossroads (Dagstuhl Seminar 18161)

Jan Aerts, Nils Gehlenborg, Georgeta Elisabeta Marai, Kay Katja Nieselt, Michael Wagner
2018 Dagstuhl Reports  
path forward for biological data visualization research.  ...  The design and implementation of such techniques lies at the intersection of the biology, bioinformatics, and data visualization fields.  ...  Acknowledgements We would like to thank all participants of the seminar for their contributions and lively discussions; we also would like to thank the scientific directorate of Dagstuhl for providing  ... 
doi:10.4230/dagrep.8.4.32 dblp:journals/dagstuhl-reports/AertsGMN18 fatcat:o6jaaovvkbb35djgwvgaqlvnmm

Using natural products for drug discovery: the impact of the genomics era

Mingzi M Zhang, Yuan Qiao, Ee Lui Ang, Huimin Zhao
2017 Expert Opinion on Drug Discovery  
Areas covered-This review highlights the importance of genomics and metagenomics in natural product discovery, and provides an overview of the technical and conceptual advances that offer unprecedented  ...  Expert opinion-Genomics and metagenomics revealed nature's remarkable biosynthetic potential and her vast chemical inventory that we can now prioritize and systematically mine for novel chemical scaffolds  ...  The development of genome editing and genome engineering technologies in natural productrelevant organisms will greatly enhance the scalability of these activation strategies in native hosts [34] .  ... 
doi:10.1080/17460441.2017.1303478 pmid:28277838 pmcid:PMC5563975 fatcat:y3svjklwezbp5cdo73kmyyswcy

Programmable RNA Sensing for Cell Monitoring and Manipulation [article]

Yongjun Qian, Jiayun Li, Shengli Zhao, Elizabeth A. Matthews, Michael Adoff, Weixin Zhong, Xu An, Michele Yeo, Christine Park, Bor-Shuen Wang, Derek G. Southwell, Z. Josh Huang
2022 bioRxiv   pre-print
Despite advances in RNA sequencing and massive accumulation of transcriptome datasets across life sciences, the dearth of technologies that leverage RNAs to observe and manipulate cell types remains a  ...  Here, we describe CellREADR (Cell access through RNA sensing by Endogenous ADAR), a programmable RNA sensing technology that leverages RNA editing mediated by ADAR (adenosine deaminase acting on RNA) for  ...  Streptavidin dye was used for visualization.  ... 
doi:10.1101/2022.05.25.493141 fatcat:5dsn2lvrjnhlddxdl7mjcj4b7i

Transformaciones en educación médica: innovaciones en la evaluación de los aprendizajes y avances tecnológicos (parte 2)

Verónica Luna de la Luz, Patricia González-Flores
2020 Investigación en Educación Médica  
practice as a key vehicle for this alignment.  ...  we serve to create the "sweet spot" needed for informed alignment.  ... 
doi:10.22201/facmed.20075057e.2020.34.20220 fatcat:loaptgxerna45obr22i4mo77d4

Methods for transcript variant discovery and alternative expression analysis : application to the study of fluorouracil resistance in colorectal cancer

Malachi Griffith
Recent advances in genome-wide microarray and sequencing platforms have begun to provide the capacity and resolution to address these challenges.  ...  For example, the approach was insensitive to isoforms with small differences in sequence content and limited by both the transcriptome annotations and the number of microarray features available at design  ...  Overview of SNPs and mutations found by genomic sequencing........... 2071.  ... 
doi:10.14288/1.0068972 fatcat:atrxurgcgjhizfcjvkzo4gsemq

Abstracts from the Astrobiology Science Conference 2004

2004 International Journal of Astrobiology  
In particular, I will discuss: (i) The requirements for carbon-based life and their dependence on the values of physical constants.  ...  I will examine recent fi ndings in cosmology and their implications for the emergence of life in the universe and the ultimate fate of life.  ...  The curriculum is aligned with National Science Education Standards and is inquiry based, emphasizing evidence and the nature of science.  ... 
doi:10.1017/s1473550404001648 fatcat:7edgphlk6bb2xf73w3rrb2vc3m

Spatiotemporal enabled Content-based Image Retrieval

Mariana Belgiu, Martin Sudmanns, Tiede Dirk, Andrea Baraldi, Stefan Lang
2016 International Conference on GIScience Short Paper Proceedings  
For efficient deployment of sensors in a WSN the coverage estimation is a critical issue. Probabilistic methods are among the most accurate models proposed for sensor coverage estimation.  ...  Wireless Sensor Networks (WSNs) are widely used for monitoring and observation of dynamic phenomena.  ...  We acknowledge the USGS Center for Excellence in Geospatial Information Science (CEGIS) for analytic advice.  ... 
doi:10.21433/b311729295dw fatcat:fulw4pw3kfh5nmfzcsy3pkisvm

The Sericum Via: A Serious Game For Preserving Tangible And Intangible Heritage Of Iran.pdf [article]

Sepehr Vaez Afshar, Sarvin Eshaghi
The Sericum Via: A Serious Game For Preserving Tangible And Intangible Heritage Of Iran Conference: ASCAAD 2021 Session: Computational Enculturation I Authors: Sarvin Eshaghi, Sepehr Vaez Afshar, Güzden  ...  Varinlioglu ASCAAD 2021: Architecture in the Age Of Disruptive Technologies Transformation and Challenges 9th International Conference of the Arab Society for Computer Aided Architectural Design Cairo  ...  Acknowledgment The Authors are grateful for the fund provided by Bartlett's Fund for Science and Engineering Research Collaboration, in a research project collaboration between Princeton university and  ... 
doi:10.6084/m9.figshare.14384318.v1 fatcat:6hrsxig5efhojhw6m2wu6w7qfm

Energy and wavelength scaling of shock-ignited inertial fusion targets

S Atzeni, A Marocchino, A Schiavi, G Schurtz
2013 New Journal of Physics  
High-quality microring resonators have been fabricated for over a decade in a variety of CMOS compatible platforms [1] and have been recently investigated for their quantum optics potential [2].  ...  Present multi-scale approach makes possible to take into account electronic effects (band alignment, charge density displacements) and thermodynamical properties (order, adhesion energy, molecular mobility  ...  Papantonis (Oxford) While we now know in details the sequence of most eukaryotic genomes, we still have only a rudimentary idea of how these genomes fold in space, or how structure affects function.  ... 
doi:10.1088/1367-2630/15/4/045004 fatcat:c4lh6z3uavbktgx4didzjqxoiy

Abstracts of Papers Presented at the 2005 Pittsburgh Conference

Peter B. Stockwell
2005 Journal of automated methods & management in chemistry (Print)  
the final program book, an omission no doubt on their behalf—my company was one of these—however I feel sure that past Pittcon organizers would have been more persistent in getting the required details for  ...  with fully sequenced genomes.  ...  The growing number of fully sequenced bacterial genomes, combined with spectacular progress made in automated sequencing of peptides obtained from gene products, that is, proteins, opens new possibilities  ... 
doi:10.1155/jammc.2005.59 pmid:18924631 pmcid:PMC2548401 fatcat:xqreduq3ibdwdkzh4l7xtj4f3e

Participatory mycotoxin management in India and the genetic determinants of symptom manifestation in the sorghum grain mold disease complex

Anthony Wenndt
The passion she exudes for her work and for the farmers it impacts has been a source of inspiration for me from the very beginning and will continue to inspire me for a lifetime.  ...  Rebecca Nelson, for her unwavering support throughout my graduate studies.  ...  Sequencing reads were aligned to the sorghum reference genome (v2.1, and filtered using the TASSEL 5.0 GBS pipeline (Glaubitz et al., 2014) .  ... 
doi:10.7298/111r-8x53 fatcat:brpx32abvngifftuq7tyqmb7ji

Cambodian Journal of Natural History Cambodian Journal of Natural History

Dr, Knud Heller, Nykøbing Zoo, Sovanmoly Hul, Dr, Andy Maxwell, Dr, Jörg Menzel, Dr, Campbell Webb
2015 unpublished
Finally, we would especially thank the Royal Government of Cambodia's Fisheries Administration, particularly Ouk Vibol and Ing Try, for their invitation to survey Cambodian coral reefs, and for their continued  ...  Thanks to Choun Phirom, Fauna & Flora International GIS Coordinator, for producing the MFMA map (Fig. 1) .  ...  data, bypassing both genome assembly and alignment.  ... 


Maria Nielsen, Louring, Michael Mullins, Finbarr
HCWH's mission is to transform healthcare worldwide so that it reduces its environmental footprint, and becomes both a community anchor for sustainability and a leader in environmental health and justice  ...  The UK will be the first country in the world to bring whole genome sequencing into routine healthcare, potentially making personalised medicine a reality for all.  ...  for a genomic medicine service in the NHS.  ... 

Reconceptualising the Creative Economy: Possibilities in Place in Rural Victoria

Melissa Kennedy
University, Victoria, Australia.This thesis was a recipient of the Planning Institute of Australia Outstanding Student Project Award for Planning Excellence 2020.  ...  A thesis submitted in total fulfillment of the requirements for the degree of Doctor of Philosophy to the School of Humanities and Social Sciences, College of Arts, Social Sciences and Commerce, La Trobe  ...  Introduction Towns across rural and regional Australia offer a strong visual reminder of externalities of past economies.  ... 
doi:10.26181/5f866fe7ba1ca fatcat:b46w6pgt4zhzflz37jkjzboyo4