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EFFECT OF LIGUSTRAZINE AGAINST MYOCARDIAL ISCHAEMIA-REPERFUSION INJURY IN RATS

Lei Lv, Shi-sen Jiang, Jun Xu, Jian-bin Gong, Yan Cheng, Shi-sen Jiang
2012 Heart  
Objectives The effect of ligustrazine (2,3,5,6-tetramethylpyrazine, TMP) on myocardial ischaemia reperfusion (IR) and the role of nitric oxide (NO) was investigated in a rat IR model. Methods The animal model was built by ligation of the left anterior descending artery of rats. Sprague-Dawley rats were randomly divided into sham, IR (35 min of regional ischaemia followed by 120 min of reperfusion), 3 TMP pretreated (TMP pretreated, 5, 10, 30 mg/kg intravenous injection, 5 min before ligation)
more » ... d TMP +L-NAME group. Infarct size, light microscopic evaluation, myocardial superoxide dismutase (SOD) activity, malondialdehyde (MDA) content, myeloperoxidase (MPO) activity, the level of interleukin-1β (IL-1β) as well as NO production were measured. Results Pretreatment with middle and high dose of TMP markedly decreased infarct size ((38.7±4.5)%, (35.2±2.3)% vs IR(50.4 ±4.6)%, p<0.05, respectively), increased SOD activity (50.2 ±3.2 U/mg, 51.2±6.4 U/mg vs IR 35.6±4.3 U/mg, p<0.05, respectively). Middle and high dose of TMP pretreatment decreased MDA content (0.417±0.069 nmol/mg, 0.331±0.023 nmol/mg vs IR 0.693±0.053nmol/mg, p<0.05, respectively) the MPO activity (6.237±0.901 U/mg, 6.201±1.263 U/mg, vs IR 8.670±1.260 U/mg, p<0.05, respectively), and the level of IL-1β (0.140±0.021, 0.132 ±0.027 pg/mg, vs IR 0.235±0.026 pg/mg, p<0.05). TMP pretreatment also alleviated the neutrophil infiltration and increased the NO level (0.404±0.041 mmol/g in the TMP-M group, 0.453 ±0.067 mmol/g in the TMP-H group vs 0.295±0.032 mmol/g in the IR group, p<0.05). However, these effects could be significantly reversed by L-NAME which abolished the increase of NO production brought by TMP. Conclusions In conclusion, ligustrazine attenuated myocardial IR injury by a dose-related manner. The cardioprotective effect of ligustrazine may relate to its effects of increasing the level of NO, decreasing the inflammatory and oxidative stress. E10 Heart 2012;98(Suppl 2): E1-E319 ABSTRACTS on 22 July 2018 by guest. Protected by copyright.
doi:10.1136/heartjnl-2012-302920a.22 fatcat:yc6q55kzbrh4jbdjg3xgkogpte

Heralded Generation of Vectorially Structured Photons With a High Purity

Hai-Jun Wu, Bing-Shi Yu, Zhi-Han Zhu, Carmelo Rosales-Guzmán, Carmelo Rosales-Guzmán, Zhi-Yuan Zhou, Zhi-Yuan Zhou, Dong-Sheng Ding, Dong-Sheng Ding, Wei Gao, Bao-Sen Shi, Bao-Sen Shi
2021 Frontiers in Physics  
Engineering vector spatial modes of photons is an important approach for manipulating high-dimension photonic states in various quantum optical experiments. In this work, we demonstrate the generation of heralded single photons with well-defined vector spatial modes by using a self-stable polarizing interferometer comprising a spatial light modulator. Specifically, it is shown that, by carefully tailoring and compensating the spatial and temporal amplitudes of manipulated photons, one can
more » ... y convert ultrafast single photons into desired spin-orbit states with an extremely high purity. This compact and robust device provides a versatile way for not only the generation, but also the manipulation and characterization of arbitrary photonic spin-orbit states.
doi:10.3389/fphy.2021.654451 doaj:dd24be1efdc74c5c85311f94722c4820 fatcat:grv5cbopwvaurgjaxf3jflu74e

Approximation of chaotic operators [article]

Geng Tian, Luoyi Shi, Sen Zhu, Bingzhe Hou
2009 arXiv   pre-print
As well-known, the concept "hypercyclic" in operator theory is the same as the concept "transitive" in dynamical system. Now the class of hypercyclic operators is well studied. Following the idea of research in hypercyclic operators, we consider classes of operators with some kinds of chaotic properties in this article. First of all, the closures of the sets of all Li-Yorke chaotic operators or distributionally chaotic operators are discussed. We give a spectral description of them and prove
more » ... t the two closures coincide with each other. Moreover, both the set of all Li-Yorke chaotic operators and the set of all distributionally chaotic operators have nonempty interiors which coincide with each other as well. The article also includes the containing relation between the closure of the set of all hypercyclic operators and the closure of the set of all distributionally chaotic operators. Finally, we get connectedness of the sets considered above.
arXiv:0905.4535v1 fatcat:jkvtjonn4ng6fgvbbkaxmppziq

Generation and reverse transformation of twisted light by spatial light modulator [article]

Zhi-Yuan Zhou, Zhi-Han Zhu, Shi-Long Liu, Shi-Kai Liu, Kai Wang, Shuai Shi, Wei Zhang, Dong-Sheng Ding, Bao-Sen Shi
2016 arXiv   pre-print
A spatial light modulator (SLM) is one of the most useful and convenient device to generate structural light beams such as twisted light and complexed images used in modern optical science. The unbounded dimension of twisted light makes it promising in harnessing information carrying ability of a single photon, which greatly enhances the channel capacity in optical communications. We perform a detail theoretical study of the birth, evolution and reverse transformation of twisted light generated
more » ... from a phase-only SLM based on diffraction theory, analytical expressions are obtained to show the special evolution behaviors of the light beam with the propagation distance. Beam intensity distributions calculated theoretically are in well agreement with experimental observations. Our findings clearly reveal how twisted light gradually emerges from a Gaussian spatial shape to a ring shape, and also the ring shape will gradually evolve to a quasi-Gaussian shape conversely, in the reverse transformation. These results will provide guidelines for using SLM in many optical experiments and OAM-mode multiplexing in optical communications.
arXiv:1612.04482v1 fatcat:4llc4d6eezdhdg27zkyocppntq

Non-destructive splitter of twisted light [article]

Yan Li, Zhi-Yuan Zhou, Dong-Sheng Ding, Wei Zhang, Shuai Shi, Bao-Sen Shi, Guang-Can Guo
2015 arXiv   pre-print
Efficiently discriminating beams carrying different orbital angular momentum (OAM) is of fundamental importance for various applications including high capacity optical communication and quantum information processing. We design and experimentally verify a distinguished method for effectively splitting different OAM-carried beams by introducing Dove prisms in a ring cavity. Because of rotational symmetry broken of two OAM-carried beams with opposite topological charges, their transmission
more » ... a will split. When mode and impedance matches between the cavity and one OAM-carried beam are achieved, this beam will transmit through the cavity, and other beam will be reflected without being destroyed their spatial shapes. In this case, the cavity acts like a polarized beam splitter. The transmitting beam can be selected at your will. The splitting efficiency can reach unity if the cavity is lossless and it completely matches with the beam. Beams carry multi-OAMs can also be effectively split by cascading ring cavities.
arXiv:1509.02691v1 fatcat:xssjhohoabgdfamxthr7e52cmq

PROTECTIVE EFFECT OF LIGUSTRAZINE IN ATTENUATING MYOCARDIAL APOPTOSIS ON RATS WITH MYOCARDIAL ISCHAEMIA REPERFUSION AND ITS MECHANISM

Lei Lv, Shi-sen Jiang, Jun Xu, Jian-bin Gong, Yan Cheng, Shi-sen Jiang
2012 Heart  
Lei Lv, Shi-sen Jiang, Jun Xu, Jian-bin Gong, Yan Cheng, Shi-sen Jiang.  ... 
doi:10.1136/heartjnl-2012-302920a.155 fatcat:svjidyu6afaovhwdjrvhvfcimu

Topological charge independent frequency conversion of twisted light [article]

Yan Li, Zhi-Yuan Zhou, Shi-Long Liu, Shi-Kai Liu, Chen Yang, Zhao-Huai Xu, Yin-Hai Li, Guang-Can Guo, Bao-Sen Shi
2018 arXiv   pre-print
Light with orbital angular momentum (OAM), or twisted light, is widely investigated in the fields of optical communications, quantum information science and nonlinear optics by harnessing its unbounded dimension. For light-matter interacting with twisted light like quantum memory and nonlinear frequency conversion, efficiencies in these processes are usually decreasing exponentially with topological charges, which severely degrades the fidelity of the output states. Here we conceive and develop
more » ... a method to eliminate the dependence of conversion efficiency on topological charges in second harmonic generation (SHG) process by utilizing a special designed image technique. The independence of SHG conversion efficiency on topological charge is verified for different topological charges, this independence is valid for various pump power. This method can be generalized to other light matter interaction processes and will revolute the field of light matter interaction with twisted light to achieve higher efficiency and higher fidelity.
arXiv:1810.07846v1 fatcat:yfzrcidcwrhu3m2thupdxm3rjy

All-optical quantum signal demultiplexer [article]

Yin-Hai Li, Wen-Tan Fang, Zhi-Yuan Zhou, Shi-Long Liu, Shi-Kai Liu, Zhao-Huai Xu, Chen Yang, Yan Li, Li-Xin Xu, Guang-Can Guo, Bao-Sen Shi
2018 arXiv   pre-print
Dense wavelength division multiplexing (DWDM) is one of the most successful methods for enhancing data transmission rates in both classical and quantum communication networks. Although signal multiplexing and demultiplexing are equally important, traditional multiplexing and demultiplexing methods are based on passive devices such as arrayed waveguides and fiber Bragg cascade filters, which, although widely used in commercial devices, lack any active tuning ability. In this work, we propose a
more » ... gnal demultiplexing method based on sum frequency generation (SFG) with two significant features: first, any signal from the common communication channel can be demultiplexed to a single user by switching the pump wavelength; second, a cheap high-performance detector can be used for signal detection. These two features were demonstrated by demultiplexing multi-channel energy-time entanglement generated by a micro-cavity silicon chip. High interference visibilities over three channels after demultiplexing showed that entanglement was preserved and verified the high performance of the demultiplexer, which will find wide application in high-capacity quantum communication networks.
arXiv:1803.00206v1 fatcat:l77p4zxqe5ds7jkafy7timpdia

Extra-cavity-enhanced difference-frequency generation at 1.63 μm [article]

Chen Yang, Shi-long Liu, Zhi-yuan Zhou, Yan Li, Yin-hai Li, Shi-kai Liu, Zhao-huai Xu, Guang-can Guo, Bao-sen Shi
2020 arXiv   pre-print
A 1632-nm laser has highly important applications in interfacing the wavelength of rubidium-based quantum memories (795 nm) and the telecom band (typically 1550 nm) by frequency conversion in three-wave mixing processes. A 1632-nm laser source based on pump-enhanced difference frequency generation is demonstrated. It has 300 mW of output power, in agreement with simulations, and a 55% quantum efficiency. An average power fluctuation of 0.51% over one hour was observed, and 200-kHz linewidth was measured using a delayed self-heterodyne method.
arXiv:2003.10122v1 fatcat:myfss2jq5vfadl3qiewmdxne5e

Classical analogy of a cat state using vortex light

Shi-Long Liu, Qiang Zhou, Shi-Kai Liu, Yan Li, Yin-Hai Li, Zhi-Yuan Zhou, Guang-Can Guo, Bao-Sen Shi
2019 Communications Physics  
Cat states are systems in a superposition of macroscopically distinguishable states; this superposition can be of either classically or quantum distinct states, regardless of the number of particles or modes involved. Here, we constructed an experimental model that simulates an optical cat state by engineering the classical orbital angular momentum of light, referred to here as an analogous cat state (a-CS). In our scheme, the behaviors of the a-CS in position space show many similarities to
more » ... quantum version of the optical cat state in phase space, for example, movement, rotation, and interference. Experimentally, the a-CS, which has two spatially localized Gaussian intensity lobes, can be evolved from "kitten" to "cat" by engineering the acquired phase hologram. Additionally, we simulated the "decoherence" of the a-CS influenced by atmospheric turbulence. The a-CS provides a reliable tool for visualizing and studying the behaviors of quantum cat states in phase space.
doi:10.1038/s42005-019-0156-2 fatcat:njyzb4g5d5fmhgahvim54qpcza

Tunable cavity-enhanced photon pairs source in Hermite-Gaussian mode [article]

Zhi-Yuan Zhou, Yan Li, Dong-Sheng Ding, Wei Zhang, Shuai Shi, Bao-Sen Shi, Guang-Can Guo
2015 arXiv   pre-print
The spatial modes of light have grasped great research interests because of its great potentials in optical communications, optical manipulation and trapping, optical metrology and quantum information processing. Here we report on generating of photon pairs in Hermite-Gaussian (HG) mode in a type-I optical parametric oscillator (OPO) operated far below threshold. The bandwidths of the photon pairs are 11.4 MHz and 20.8MHz for two different HG modes respectively, which is capable to be stored in
more » ... cold Rubidium atomic ensembles. From correlation measurements, non-classical properties of HG modes in different directions are verified by tuning the cavity. Our study provides an effective way to generate photon pairs with narrow bandwidth in high order spatial modes for high dimensional quantum communication.
arXiv:1505.05633v1 fatcat:fgk6iv7evjconpge6vlmrvpzxe

Orbital angular momentum photonic quantum interface [article]

Zhi-Yuan Zhou, Yan Li, Dong-Sheng Ding, Wei Zhang, Shuai Shi, Bao-Sen Shi, Guang-Can Guo
2015 arXiv   pre-print
Express 2014; 22: 20298-20310. 42 Zhou ZY, Li Y, Ding DS, Zhang W, Shi S, Shi BS, et al.  ...  Photon. 2015; 9: 83-87. 27 Ding DS, Zhou ZY, Shi BS, Guo GC. Single-photon-level quantum imaging memory based on cold atomic ensembles. Nat.  ... 
arXiv:1410.7543v2 fatcat:gylclnwoizbczhte7lzuy2twgu

Compressive focused beamforming based on vector sensor array

Shi Jie, Yang De-Sen, Shi Sheng-Guo, Hu Bo, Zhu Zhong-Rui
2016 Wuli xuebao  
Broadband target beam-space transformation in generalized likelihood ratio test using acoustic vector sensor array
doi:10.7498/aps.65.024302 fatcat:qhmz65ovx5batd6ae3upbeufmu

Physiological and Biochemical Mechanism of Allelopathy of Secalonic Acid F on Higher Plants

Ren Sen Zeng, Shi Ming Luo, Yue Hong Shi, Mu Biao Shi, Cong Yong Tu
2001 Agronomy Journal  
phenolic acids. All of these have inhibitory activity, and most of them produce different biological lesions (Ein-Our previous work indicated that secalonic acid F (SAF) was the hellig, 1995). major allelochemical produced by Aspergillus japonicus. Studies showed that SAF markedly inhibited the seedling growth of sorghum Secalonic acids, a series of ergochrome pigments, exist (Sorghum vulgare Pers.), hairy beggarticks (Bidens pilosa L.), and in a group of food-born fungal metabolites (Betina,
more » ... rnyardgrass (Echinochloa crus-galli (L.) Beauv.). It significantly 1984). These fungi produce one or more secalonic acids reduced the activities of superoxide dismutase (SOD) and peroxidase when they grow on rice (Oryza sativa L.), corn (Zea (POD) at a concentration of 0.3 mM. Secalonic acid F enhanced mays L.), and rye (Secale cereale L.) (Kurobane et al., malondialdehyde (MDA) contents, but it lowered the content of chlo-1979). Secalonic acid A is a highly potent phytotoxic rophyll (CHL) a and b as well as the photosynthetic rates of tested compound that is isolated from several fungi such as plants. Respiration, membrane permeability, and abscisic acid (ABA) Aspergillus aculeatus (Andersen et al., 1977) and Pyrecontent increased after treatment with SAF, but the reduction activity nochaeta terrestris (Steffens and Robeson, 1987). Secaof the root system was lowered. There is no remarkable change in lonic acid D, a metabolite produced by Penicillium oxthe soluble proteins of plants that are treated with SAF. Transmission electron microscope (TEM) observations showed that treated plants aium, causes storage rot of cucumber (Cucumis sativus exhibited amorphous mitochondria without integral membranes and L.) and tomato (Lycopersicon lycopersicum L.) (Jarvis swelling chloroplasts without membranes in a disorderly arrangement. et al., 1990). It is an inhibitor of protein kinase C and The SAF treatment also damaged the stratiform structure of the cyclic AMP-dependent protein kinase (Wang et al., chloroplasts and the membranes and structure of the nuclei. These 1996). Secalonic acid F was originally isolated from results suggest that SAF may weaken the protective ability of plant Claviceps purpurea (Aberhart et al., 1965). Our previous tissues against membrane lipid peroxidation and damage the whole work indicated that SAF was a major allelochemical membrane system of plants, resulting in the ultrastructure destruction produced by A. japonicus (Zeng et al., 2001). Details of chloroplasts, mitochondria, and nuclei. Cell ultrastructure destrucare needed about the mode of action of secalonic acids tion causes a reduction of photosynthesis and root activities and an increase in respiration. These abnormal physiological processes con-against higher plants to deepen the understanding of tribute to the inhibition of plant growth. the chemical interaction between fungi and higher plants. Our objective was to determine the physiological and biochemical mechanism of allelopathy of SAF.
doi:10.2134/agronj2001.93172x fatcat:bkdybbhgxfhwbhnrlgsaeelieq

Super-resolving phase measurement with short wavelength NOON states by quantum frequency up-conversion [article]

Zhi-Yuan Zhou, Shi-Long Liu, Shi-Kai Liu, Yin-Hai Li, Dong-Sheng Ding, Guang-Can Guo, Bao-Sen Shi
2017 arXiv   pre-print
Precise measurements are the key to advances in all fields of science. Quantum entanglement shows higher sensitivity than achievable by classical methods. Most physical quantities including position, displacement, distance, angle, and optical path length can be obtained by optical phase measurements. Reducing the photon wavelength of the interferometry can further enhance the optical path length sensitivity and imaging resolution. By quantum frequency up conversion, we realized a short
more » ... h two photon number entangled state. Nearly perfect Hong Ou Mandel interference is achieved after both 1547-nm photons are up converted to 525 nm. Optical phase measurement of two photon entanglement state yields a visibility greater than the threshold to surpass the standard quantum limit. These results offer new ways for high precision quantum metrology using short wavelength quantum entanglement number state.
arXiv:1703.04253v1 fatcat:wa5a45u4wfe3xjsai3lnwt6qvu
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