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Semantic integration of medication data into the EHOP Clinical Data Warehouse

Denis Delamarre, Guillaume Bouzille, Kevin Dalleau, Denis Courtel, Marc Cuggia
2015 Studies in Health Technology and Informatics  
Reusing medication data is crucial for many medical research domains. Semantic integration of such data in clinical data warehouse (CDW) is quite challenging.  ...  Our objective was to develop a reliable and scalable method for integrating prescription data into EHOP (a French CDW).  ...  The French National Agency of Research (ANR) funded this research work (RAVEL ANR-11-TECS-012).  ... 
pmid:25991243 fatcat:drhti4s27rdengvab6dkryp5zy

How to Optimize Connection Between PACS and Clinical Data Warehouse: A Web Service Approach Based on Full Metadata Integration [chapter]

Pierre Lemordant, Guillaume Bouzille, Romain Mathieu, Ronan Thenault, Bernard Gibaud, Cyril Garde, Boris Campillo-Gimenez, Didier Goudet, Sébastien Delarche, Yann Roland, Marc Cuggia
2022 Studies in Health Technology and Informatics  
Integrating such data in a Clinical Data Warehouse (CDW) implies to unlock the PACS and RIS and to address interoperability and semantics issues.  ...  Clinical image data analysis is an active area of research.  ...  Acknowledgments We would like to thank the French National Research Agency (ANR), for funding this work in the framework of the LabCom LITIS project (grant no.  ... 
doi:10.3233/shti220025 pmid:35672964 fatcat:bicovvd2fng7tcazgek6klifvy

Clinical Data Analytics With Time-Related Graphical User Interfaces: Application to Pharmacovigilance

Thibault Ledieu, Guillaume Bouzillé, Elisabeth Polard, Catherine Plaisant, Frantz Thiessard, Marc Cuggia
2018 Frontiers in Pharmacology  
These tools have been developed and tested using the biomedical data warehouse eHOP (Hospital Biomedical Data Warehouse) of the Rennes University Hospital Centre.  ...  This activity can be time-consuming because it requires the collection of both patient and medication information.  ...  Elisabetta Andermarcher for her careful proofreading of the paper.  ... 
doi:10.3389/fphar.2018.00717 pmid:30233354 pmcid:PMC6127627 fatcat:odvfzyjxxbc7ffvvj447psrpiu

Timeline representation of clinical data: usability and added value for pharmacovigilance

Thibault Ledieu, Guillaume Bouzillé, Frantz Thiessard, Karine Berquet, Pascal Van Hille, Eric Renault, Elisabeth Polard, Marc Cuggia
2018 BMC Medical Informatics and Decision Making  
Methods: The timeline prototype was assessed using the biomedical data warehouse eHOP (from entrepôt de données biomédicales de l'HOPital) of the Rennes University Hospital Centre.  ...  This activity requires the collection and analysis of data from the patient record or any other sources to find clues of a causality link between the drug and the ADR.  ...  Catherine Plaisant, Associate Director of Research of the Human-Computer Interaction Laboratory for her advices in the methodological choices and her attentive reading of the manuscript.  ... 
doi:10.1186/s12911-018-0667-x fatcat:ljmrm6t4fjhxzahwt2ucykzedq

Sharing Health Big Data for Research - A Design by Use Cases: The INSHARE Platform Approach

Guillaume Bouzillé, Richard Westerlynck, Gautier Defossez, Dalel Bouslimi, Sahar Bayat, Christine Riou, Yann Busnel, Clara Le Guillou, Jean-Michel Cauvin, Christian Jacquelinet, Patrick Pladys, Emmanuel Oger (+4 others)
2017 Studies in Health Technology and Informatics  
Platform architecture integrates: data repository and hosting, semantic integration services, data processing, aggregate computing, data quality and integrity monitoring, Id linking, multisource query  ...  Lack of interoperability: compartmentalized and syntactically/semantica heterogeneous data. INSHARE project using experimental proof of concept explores how recent technologies overcome such issues.  ...  Acknowledgements We would like to thank the French National Research Agency (ANR), for funding this work inside the INSHARE (INtegrating and Sharing Health dAta for Research) project (grant no.  ... 
pmid:29295104 fatcat:zva6jsdbpfhsxg75l3k377uxai

Building a Semantic Health Data Warehouse: Evaluation of a search tool in Clinical trials (Preprint)

Romain Lelong, Lina F. Soualmia, Julien Grosjean, Mehdi Taalba, Stéfan J. Darmoni
2019 JMIR Medical Informatics  
The huge amount of clinical, administrative, and demographic data recorded and maintained by hospitals can be consistently aggregated into health data warehouses with a uniform data model.  ...  In 2017, Rouen University Hospital (RUH) initiated the design of a semantic health data warehouse enabling both semantic description and retrieval of health information.  ...  Acknowledgments The authors are grateful to Nikki Sabourin-Gibbs, RUH, for help in editing the paper.  ... 
doi:10.2196/13917 pmid:31859675 pmcid:PMC6942180 fatcat:rhicbo6lk5fuvlnaod3eioiw7y

Evaluation of Doc'EDS: a French semantic search tool to query health documents from a clinical data warehouse

Thibaut Pressat-Laffouilhère, Pierre Balayé, Badisse Dahamna, Romain Lelong, Kévin Billey, Stéfan J. Darmoni, Julien Grosjean
2022 BMC Medical Informatics and Decision Making  
Methods Doc'EDS is a search tool built on top of the clinical data warehouse developed at Rouen University Hospital.  ...  The Doc'EDS system provides a graphic user interface to search documents in French. The aim of this study was to present the Doc'EDS tool and to provide a formal evaluation of its semantic features.  ...  Acknowledgements The authors are grateful to Nikki Sabourin-Gibbs (Rouen University Hospital) for her help with editing the manuscript.  ... 
doi:10.1186/s12911-022-01762-4 pmid:35135538 pmcid:PMC8822768 fatcat:o355dsgmgrbrnfq4w7wddpwkga

Untangling Data in Precision Oncology – A Model for Chronic Diseases?

Xosé M. Fernández
2020 IMIA Yearbook of Medical Informatics  
All our analogue medical records are rendered as sequences of zeros and ones changing how we capture and share data.  ...  Methods: From nineteenth-century medical notes consisting entirely of narrative description to standardised forms recording physical examination and medical notes, we have nowadays moved to electronic  ...  The greatest gratitude to the generosity of all our donors for the support provided to the Curie Foundation to beat cancer together.  ... 
doi:10.1055/s-0040-1701985 pmid:32823314 fatcat:xh257v3mxfaqjlz3kyhbv65ghi

How the new European data protection regulation affects clinical research and recommendations?

Jacques Demotes-Mainard, Catherine Cornu, Aurélie Guérin, Pierre-Henri Bertoye, Romain Boidin, Serge Bureau, Jean-Marie Chrétien, Cécile Delval, Dominique Deplanque, Claude Dubray, Luc Duchossoy, Valérie Edel (+13 others)
2019 The´rapie (Paris)  
Clinical research on human subjects or their data is confronted with conflicting requirements with, on one hand, the principle of open science (transparency and data sharing), the possibilities offered  ...  (4) to facilitate access to data warehouses by providing technological and methodological aids.  ...  The new full-text search and indexing technologies, through semantic enrichment via medical ontologies, make it possible to index and query unstructured textual documents such as medical observations and  ... 
doi:10.1016/j.therap.2018.12.004 pmid:30642661 fatcat:kzrwnikhurbrvfdrhnk7qxqy64

Indexing Imaging Reports for Data Sharing: A Study of Mapping Using RadLex Playbook and LOINC

Pierre Lemordant, Fleur Mougin, Sandie Cabon, Yves Gandon, Guillaume Bouzillé, Marc Cuggia
New use cases and the need for quality control and imaging data sharing in health studies require the capacity to align them to reference terminologies.  ...  We performed a manual mapping of the 200 most frequent imaging report titles at our center (i.e. 73.2% of all imaging exams).  ...  Acknowledgment We would like to thank the French National Research Agency (ANR), for funding this work in the framework of the LabCom LITIS project (grant no. ANR-17-LCV1-0004).  ... 
doi:10.3233/shti220465 pmid:35612083 fatcat:o3cez27a4vhxjf6idk6d6bnpsm