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Modeling Tissue Growth Within Nonwoven Scaffolds Pores

Sharon L. Edwards, Jeffrey S. Church, David L.J. Alexander, Stephen J. Russell, Eileen Ingham, John A.M. Ramshaw, Jerome A. Werkmeister
<span title="">2011</span> <i title="Mary Ann Liebert Inc"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/egnn67zzezdhpl5n74odbtduhe" style="color: black;">Tissue Engineering. Part C, Methods</a> </i> &nbsp;
Ingham and S.J. Russell are supported by the Leeds Centre of Excellence in Medical Engineering funded by the Wellcome Trust and EPSRC, WT088908/z/09/z.  ...  These results were reflected in the Live/Dead assay ( Fig. 2A, B) , with almost all of the cells viable.  ...  This was associated with ECM secretion, as observed in Live/Dead and SEM micrographs (data not shown).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1089/ten.tec.2010.0182">doi:10.1089/ten.tec.2010.0182</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/20687775">pmid:20687775</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3154458/">pmcid:PMC3154458</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/ze2h2nw3pvbablhgryvvoe5s3i">fatcat:ze2h2nw3pvbablhgryvvoe5s3i</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20191014230230/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3154458&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/c2/b0/c2b0dda07ee2303d7451b998ea0be1a690ab84b9.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1089/ten.tec.2010.0182"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154458" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

The effect of 3D hydrogel scaffold modulus on osteoblast differentiation and mineralization revealed by combinatorial screening

Kaushik Chatterjee, Sheng Lin-Gibson, William E. Wallace, Sapun H. Parekh, Young Jong Lee, Marcus T. Cicerone, Marian F. Young, Carl G. Simon
<span title="">2010</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/chiheds2c5dvloepqqfcaaebe4" style="color: black;">Biomaterials</a> </i> &nbsp;
Cells are known to sense and respond to the physical properties of their environment and those of tissue scaffolds. Optimizing these cellematerial interactions is critical in tissue engineering.  ...  In this work, a simple and inexpensive combinatorial platform was developed to rapidly screen three-dimensional (3D) tissue scaffolds and was applied to screen the effect of scaffold properties for tissue  ...  This article, a contribution of NIST, is not subject to US copyright. Certain equipment and instruments or materials are identified in the paper to adequately specify the experimental details.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.biomaterials.2010.03.024">doi:10.1016/j.biomaterials.2010.03.024</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/20378163">pmid:20378163</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3125577/">pmcid:PMC3125577</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/pobohyx43bchvjhnrjrlkjsfqi">fatcat:pobohyx43bchvjhnrjrlkjsfqi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200320052816/https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=902328" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/09/91/0991294f8ec74b6764debad93dde9cca326d8039.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.biomaterials.2010.03.024"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125577" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Human stem cell delivery for treatment of large segmental bone defects

Kenneth M. Dupont, Kapil Sharma, Hazel Y. Stevens, Joel D. Boerckel, Andrés J. García, Robert E. Guldberg
<span title="2010-01-19">2010</span> <i title="Proceedings of the National Academy of Sciences"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/nvtuoas5pbdsllkntnhizy4f4q" style="color: black;">Proceedings of the National Academy of Sciences of the United States of America</a> </i> &nbsp;
In summary, augmentation of polymeric scaffolds with stem cells derived from fetal and adult tissues significantly enhanced healing of large segmental bone defects; however, QD labeling of stem cells eliminated  ...  the observed therapeutic effect and failed to conclusively track stem cell location long-term in vivo. bone tissue engineering | cell tracking | in vivo | quantum dots | stem cells  ...  We thank Darwin Prockop (Texas A&M University) for the supply of hMSCs, Anthony Atala (Wake Forest University) for the supply of hAFS cells, and W.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1073/pnas.0905444107">doi:10.1073/pnas.0905444107</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/20133731">pmid:20133731</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC2840521/">pmcid:PMC2840521</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/wmyluzwbb5dubmhqzhfx64nlim">fatcat:wmyluzwbb5dubmhqzhfx64nlim</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20180725170909/http://www.pnas.org/content/pnas/107/8/3305.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/47/95/47952292d192a07fdb14642ed9f179f611bf43bd.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1073/pnas.0905444107"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840521" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Biomimetic Methacrylated Gelatin Hydrogel Loaded With Bone Marrow Mesenchymal Stem Cells for Bone Tissue Regeneration

Jun Li, Wenzhao Wang, Mingxin Li, Ping Song, Haoyuan Lei, Xingyu Gui, Changchun Zhou, Lei Liu
<span title="2021-12-02">2021</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/tkuhrcyiufdxtkdmjqvay6f2ua" style="color: black;">Frontiers in Bioengineering and Biotechnology</a> </i> &nbsp;
In conclusion, the bio-GelMA scaffold can be used as a cell carrier of BMSC to promote the repair of segmental bone defects and has great potential in future clinical applications.  ...  Bone marrow mesenchymal stem cells (BMSCS) were encapsulated in Bio-GelMA scaffolds to examine the therapeutic effects of ECM-loaded cells in a 3D environment simulated for segmental bone defects.  ...  AUTHOR CONTRIBUTIONS JL conducted prepared the materials and in vivo experiments. ML, XG, and HL conducted the in vitro experiments. WW wrote the original draft. PS conducted the software processing.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fbioe.2021.770049">doi:10.3389/fbioe.2021.770049</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/34926420">pmid:34926420</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8675867/">pmcid:PMC8675867</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/pm6mifyhaffsbad2lp22iaigpq">fatcat:pm6mifyhaffsbad2lp22iaigpq</a> </span>
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Upcyte® Microvascular Endothelial Cells Repopulate Decellularized Scaffold

Katharina Scheller, Iris Dally, Nadja Hartmann, Bernhard Münst, Joris Braspenning, Heike Walles
<span title="">2013</span> <i title="Mary Ann Liebert Inc"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/egnn67zzezdhpl5n74odbtduhe" style="color: black;">Tissue Engineering. Part C, Methods</a> </i> &nbsp;
Initial experiments using MTT and Live/Dead staining indicate that upcyte mvECs repopulate the BioVaSc Scaffold.  ...  A general problem in tissue engineering is the poor and insufficient blood supply to guarantee tissue cell survival as well as physiological tissue function.  ...  Martin Schenk from the experimental medicine of the University of Tü bingen for making the operating room available and Dominique Tordy for the preparation of the matrices.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1089/ten.tec.2011.0723">doi:10.1089/ten.tec.2011.0723</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/22799502">pmid:22799502</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3522132/">pmcid:PMC3522132</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/sxiomo4hvzacjety3k3tzvgv74">fatcat:sxiomo4hvzacjety3k3tzvgv74</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200206034115/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3522132&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/b6/35/b635d3662f417d2926c6f9bddb776842c2dded55.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1089/ten.tec.2011.0723"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522132" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Mammalian Cell Viability Methods in 3D Scaffolds for Tissue Engineering [chapter]

Benjamin Gantenbein, Andreas S. Croft, Marie Larraillet
<span title="2020-09-30">2020</span> <i title="IntechOpen"> Fluorescence Methods for Investigation of Living Cells and Microorganisms </i> &nbsp;
Modern methods have evolved in tissue engineering to evaluate cell viability (CV) in 3D scaffolds and tissues.  ...  These involve either the usage of 3D confocal laser microscopy of live or fixed tissues, or separation of cells from the tissue, either live or fixed, and then their analysis by flow cytometry.  ...  They are grateful to László Kupcsik and Marije de Jong (Van der Werf) for the assistance in the development of the ImageJ 'Cellcounter' macro and the MatLab routine 'Cell Viability Estimator for 3D Scaffolds  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5772/intechopen.93078">doi:10.5772/intechopen.93078</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/vug2fh4jmvhpzi63o4hxyti45a">fatcat:vug2fh4jmvhpzi63o4hxyti45a</a> </span>
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Perfusion Flow Enhances Viability and Migratory Phenotype in 3D-Cultured Breast Cancer Cells

Alice Pasini, Joseph Lovecchio, Marilisa Cortesi, Chiara Liverani, Chiara Spadazzi, Laura Mercatali, Toni Ibrahim, Emanuele Giordano
<span title="2021-02-04">2021</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/imwgooosl5b4lgzai3w2my5g5y" style="color: black;">Annals of Biomedical Engineering</a> </i> &nbsp;
In this setting however, non-uniform cell distribution and biological behaviors appear throughout the scaffold, due to reduced diffusion of oxygen and nutrients.  ...  In particular, the use of 3D cell culture introduces variables, such as cell-cell and cell-extracellular matrix interactions; cell features such as survival, proliferation and migration are consequently  ...  Live/dead images (Figs. 3a-3c) were analyzed to quantify (Fig. 3d ) the segmented areas of the scaffold occupied by live and dead cells, respectively.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s10439-021-02727-w">doi:10.1007/s10439-021-02727-w</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33543395">pmid:33543395</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8455496/">pmcid:PMC8455496</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/newv34wkirfadbllamczhszeeq">fatcat:newv34wkirfadbllamczhszeeq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210429122840/https://link.springer.com/content/pdf/10.1007/s10439-021-02727-w.pdf?error=cookies_not_supported&amp;code=ee6d042c-18e2-41ee-b2cb-297ed33c566a" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/5a/5b/5a5b81b9a4408e859abb708e3097f9b9ea74da5b.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s10439-021-02727-w"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455496" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Biochemical and Physical Signal Gradients in Hydrogels to Control Stem Cell Behavior

Oju Jeon, Daniel S. Alt, Stephen W. Linderman, Eben Alsberg
<span title="2013-08-25">2013</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/eiwzqueihbaftmngl7dgw6sb7e" style="color: black;">Advanced Materials</a> </i> &nbsp;
This simple, cytocompatible and versatile gradient system may be a valuable tool for researchers in biomaterials science to control stem cell fate in 3D and guide tissue regeneration.  ...  Three-dimensional (3D) gradients of biochemical and physical signals in macroscale, degradable hydrogels have been engineered that can regulate photoencapsulated human mesenchymal stem cell (hMSC) behavior  ...  (B) Representative live/dead photomicrographs of photoencapsulated hMSCs in odd-numbered segments and (C) quantification of DNA content in even-numbered segments of stiffness gradient alginate hydrogels  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/adma.201302364">doi:10.1002/adma.201302364</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23983019">pmid:23983019</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3863582/">pmcid:PMC3863582</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/i4eah3azkndtbkvhasbkhtaqfq">fatcat:i4eah3azkndtbkvhasbkhtaqfq</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200206093703/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3863582&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/97/b0/97b05bf8505d0cc443a71de90873639ec71ea4e9.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/adma.201302364"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> wiley.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863582" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Magnetic Hydroxyapatite Bone Substitutes to Enhance Tissue Regeneration: Evaluation In Vitro Using Osteoblast-Like Cells and In Vivo in a Bone Defect

Silvia Panseri, Carla Cunha, Teresa D'Alessandro, Monica Sandri, Alessandro Russo, Gianluca Giavaresi, Maurilio Marcacci, Clark T. Hung, Anna Tampieri, Jorge Sans Burns
<span title="2012-06-07">2012</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a> </i> &nbsp;
In case of degenerative disease or lesion, bone tissue replacement and regeneration is an important clinical goal.  ...  Such results identify this scaffold as particularly relevant for bone tissue regeneration and open new perspectives for the application of a magnetic field in a clinical setting of bone replacement, either  ...  After 14 days, cells had infiltrated into the scaffold and a high number of live cells were seen in all groups (Fig. 3F, G) .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0038710">doi:10.1371/journal.pone.0038710</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/22685602">pmid:22685602</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3369900/">pmcid:PMC3369900</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/rbmpsjegkff57jpmgnvjo6nq6q">fatcat:rbmpsjegkff57jpmgnvjo6nq6q</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20191020003704/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3369900&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/25/57/2557960d12d44b0484607925c9a89b159dc50af9.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0038710"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> plos.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369900" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Cytocompatibility and osteogenesis evaluation of HA/GCPU composite as scaffolds for bone tissue engineering

Jingjing Du, Qin Zou, Yi Zuo, Yubao Li
<span title="">2014</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ucfvmf67ybdrdogcptksyifate" style="color: black;">International Journal of Surgery</a> </i> &nbsp;
The scaffold and cell-seeded scaffold were implanted in defects (V3 mm 3 mm) of femoral condyle of SpragueeDawley rats, respectively.  ...  New bone could extensively form in both the scaffold and cell-seeded scaffold. It indicates that the HA/GCPU composite scaffold has good prospect for bone repair and regeneration.  ...  The newly formed bone tissue has appeared around the scaffold and in the pores of scaffold.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.ijsu.2014.03.005">doi:10.1016/j.ijsu.2014.03.005</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/24657710">pmid:24657710</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/kmkf4qby7rdafmppexnbdugpxy">fatcat:kmkf4qby7rdafmppexnbdugpxy</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190318072109/https://core.ac.uk/download/pdf/82796591.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/5a/ca/5aca0c75e4c6bbce3fd13c2b8dcab7748a573316.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.ijsu.2014.03.005"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> elsevier.com </button> </a>

Combining adipose-derived stem cells, resorbable scaffolds and growth factors: an overview of tissue engineering

George K B Sándor, Riitta Suuronen
<span title="">2008</span> <i title="Canadian Dental Association"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/c3ha7n5tt5cuxabx5hmnhsn2pa" style="color: black;">Journal of the Canadian Dental Association</a> </i> &nbsp;
Interdependency exists between adipogenesis, the formation of fat tissue from stem cells, and osteogenesis, the formation of bone from its stem-cell precursors.  ...  This review discusses potential future relationships between autogenous adipose-derived stem cells, growth factors and resorbable scaffolds for future tissue-engineering applications.  ...  Acknowledgments: The authors wish to acknowledge the hard work and  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/18353203">pmid:18353203</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/oo546hqkkrbpblgh5hk4hyxfby">fatcat:oo546hqkkrbpblgh5hk4hyxfby</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20170808030437/http://www.cda-adc.ca/jcda/vol-74/issue-2/167.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/57/b0/57b0ce07a98aaf2a005aec1a41c4980b59a50a0f.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a>

Numerical simulation of fluid field and in vitro three-dimensional fabrication of tissue-engineered bones in a rotating bioreactor and in vivo implantation for repairing segmental bone defects

Kedong Song, Hai Wang, Bowen Zhang, Mayasari Lim, YingChao Liu, Tianqing Liu
<span title="2012-10-05">2012</span> <i title="Springer Nature"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/kg323yn23zhkrdbyys5mmy5loa" style="color: black;">Cell stress &amp; chaperones (Print)</a> </i> &nbsp;
In addition, in vitro three-dimensional fabrication of tissue-engineered bones was carried out in optimized bioreactor conditions, and in vivo implantation using fabricated bones was performed for segmental  ...  According to the simulation results, the dynamic pressure, velocity, and shear stress around the surface of cell-scaffold construction periodically changed at different locations of the RWVB, which could  ...  Universities (DUT11SM09/DUT12JB09), and the SRF for ROCS, SEM.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s12192-012-0370-2">doi:10.1007/s12192-012-0370-2</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/23054889">pmid:23054889</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC3581632/">pmcid:PMC3581632</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/5pn5zsrcozejjbrjzvpd45ksq4">fatcat:5pn5zsrcozejjbrjzvpd45ksq4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200208142206/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC3581632&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/59/8d/598d7ea9fe4cd89259e8881df0f83ed1f3bae5f1.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1007/s12192-012-0370-2"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> springer.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581632" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Electroactive barium titanate coated titanium scaffold improves osteogenesis and osseointegration with low-intensity pulsed ultrasound for large segmental bone defects

Bo Fan, Zheng Guo, Xiaokang Li, Songkai Li, Peng Gao, Xin Xiao, Jie Wu, Chao Shen, Yilai Jiao, Wentao Hou
<span title="2020-07-15">2020</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/jxi4de7m2rabvfrefkjirfblii" style="color: black;">Bioactive Materials</a> </i> &nbsp;
6 and 12 weeks after implantation in large segmental bone defects in the radius of rabbits compared with those resulting from the pTi condition.  ...  The activity of bone marrow mesenchymal stem cells, including adhesion, proliferation, and gene expression, was significantly superior in the BaTiO3/pTi, pTi + LIPUS, and BaTiO3/pTi + LIPUS groups than  ...  the live and dead cells.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.bioactmat.2020.07.001">doi:10.1016/j.bioactmat.2020.07.001</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/32695938">pmid:32695938</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7363989/">pmcid:PMC7363989</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/syhaori5jrgangmnl55vl4zte4">fatcat:syhaori5jrgangmnl55vl4zte4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200716035707/https://pdf.sciencedirectassets.com/313777/1-s2.0-S2452199X20X00053/1-s2.0-S2452199X20301286/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEAwaCXVzLWVhc3QtMSJHMEUCIGwqE%2BjiN760N0BQuW7G7w0Hduo8m3u1ggM%2B6de8PotKAiEAkapi%2FNZobgkJxfOMk%2BfuJCZ6DtgyQ%2BXsBKS8cFdm9hAqvQMItf%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FARADGgwwNTkwMDM1NDY4NjUiDAliGzJ0hPan0hWi9SqRAx2eFZo%2FA34sHi5Jnu6Q9A49Hlb7wjD3eFeHE8ujunLi4LERyzvHn0Tjw7GSms9W7za%2FLHF%2BSSem3CO%2BUjNQbTUJW2WXZJxN5%2BJwWr%2BSQdJv%2BtWt22txfrgMw7SbkwPy1UY49uOD3qDtPtY1l1RgxwnSWvSXjAc74lwpyIcKGAKkueO6m8p65Rzc8HFvAoggzWTukgvNeXDZD3s5MicX2j4M2xBkeKb54PGztLO%2Biv3sQ60U8J5IADMKx060UgH2dm5erwEELLwD5HIIHGxWtuvHXpVEZpdbSm0OypXdietksHFecnCmKVYlUNTVTW9QTvHlhoN3LR4CKNwi5BCGQ42YhzsBY1v%2BaPBksTANAD2KCirTdxGQZqHlOKiNDvXqkkrrFj22szVVnYeHE58SxSNf%2BEm%2BVUDFYWTCmDmu82Lu3ekXxv6aS0MJX5ImGGFoPrwh3LupkZwhW2%2B%2BxtMaqb%2FeuZ1dzpMkodXtlzNscZVMgQtqKSnr7wxMBpkhFkUlBQmKqzakcon%2F8Ffj7W5bF0ZnMO%2BUv%2FgFOusBVTrnJWUmZb4nmKEPcRZX%2BH1snoie3Ms3Jl7hFOSrmqAUP9Tctycu%2BskjKXkT5zavpYiRhNYCcXIqRDGuJsarHaJpPhX%2FlKT5mlUoo9lTw0qdGeyum3GsUBxIyrqmd22pT5%2FL3%2FzUoE6qAP63wHLcVF0HrF7VfQ4YDUE0aptqFc%2FLZSuHQa%2FiGigrAW%2BX8BkfqMPJ9gN%2FaA%2Biklphc7Ry%2FPquudy5ZBWghMpOfRsfqfQ373FOJ1Se8ANVpbHpHgy3d6%2Bu7Z%2BeYX3C13if4im%2BDvwCbMsGH%2B3cZUzxOylEBYuzWwLCBuYg5T%2BdwQ%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200716T035640Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY4GYPTCOU%2F20200716%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=7b67cc60f9d3da727d711f7f881258ba7eb2246099c5f4231cd566eb4a157598&amp;hash=5ff6897af43527f6f981ce1d3429510a408abc4c5cd25d620850d3331ea3abb6&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S2452199X20301286&amp;tid=spdf-d9a3f34b-4b59-468e-824a-5f9dfef8f538&amp;sid=3c30e15f74f48047fc3a2a68762701172924gxrqa&amp;type=client" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/1e/25/1e25699a0f7fdefd96a05df96d30a30cdc92b2e2.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.bioactmat.2020.07.001"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363989" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

A standalone bioreactor system to deliver compressive load under perfusion flow to hBMSC-seeded 3D chitosan-graphene templates

Joseph Lovecchio, Paolo Gargiulo, Jose Luis Vargas Luna, Emanuele Giordano, Ólafur Eysteinn Sigurjónsson
<span title="2019-11-14">2019</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/tnqhc2x2aneavcd3gx5h7mswhm" style="color: black;">Scientific Reports</a> </i> &nbsp;
The availability of engineered biological tissues holds great potential for both clinical applications and basic research in a life science laboratory.  ...  After using the dynamic culture protocol, there was evidence of a larger number of viable cells within the inner core of the scaffold and of enhanced extracellular matrix mineralization.  ...  Quantitative analysis of the total amount of scaffold area covered by the live cells (green areas) and dead cells (red areas) is also shown (i = live cells; j = dead cells, where "side" corresponds to  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41598-019-53319-7">doi:10.1038/s41598-019-53319-7</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31728040">pmid:31728040</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6856067/">pmcid:PMC6856067</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/dirm2bhoffdbxglb4ac74ziv4m">fatcat:dirm2bhoffdbxglb4ac74ziv4m</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20191116062029/https://www.nature.com/articles/s41598-019-53319-7.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/20/24/2024a24d55c55720af627463472e85635f730c72.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1038/s41598-019-53319-7"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856067" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

A Study of BMP-2-Loaded Bipotential Electrolytic Complex around a Biphasic Calcium Phosphate-Derived (BCP) Scaffold for Repair of Large Segmental Bone Defect

Kallyanashis Paul, Andrew R. Padalhin, Nguyen Thuy Ba Linh, Boram Kim, Swapan Kumar Sarkar, Byong Taek Lee, Syam Nukavarapu
<span title="2016-10-06">2016</span> <i title="Public Library of Science (PLoS)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/s3gm7274mfe6fcs7e3jterqlri" style="color: black;">PLoS ONE</a> </i> &nbsp;
In vitro studies such as MTT, live/dead, cell proliferation and cell differentiation were performed. The scaffold was implanted into a 12 mm critical size defect of a rabbit radius.  ...  Application of the bipotential polyelectrolyte complex embedded in a spongy scaffold for faster healing of large segmental bone defects (LSBD) can be a promising endeavor in tissue engineering application  ...  The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The authors would like to thank Dr. Hae Il Jung and Mr.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0163708">doi:10.1371/journal.pone.0163708</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/27711142">pmid:27711142</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5053543/">pmcid:PMC5053543</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/redketahhrbfzm6tbbhu54uf6q">fatcat:redketahhrbfzm6tbbhu54uf6q</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20171012023024/http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0163708&amp;type=printable" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/1f/85/1f85891faf9afe99b8aa9d0a014b01de270a7b0a.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1371/journal.pone.0163708"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> plos.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053543" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>
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