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Measuring Paradigmaticness of Disciplines Using Text

Eliza Evans, Charles Gomez, Daniel McFarland
2016 Sociological Science  
Using these language samples, we measure the two core concepts of paradigmaticness-consensus and rapid discovery (Collins 1994)-and show the relative positioning of eight example disciplines on each of  ...  Drawing on the text of published articles in the Web of Science, we build samples of disciplinary discourse.  ...  We then operationalize our concepts-consensus, stability, and rapid discovery-as measures in the context of our focal samples of disciplinary discourse in eight scientific and social scientific disciplines  ... 
doi:10.15195/v3.a32 fatcat:lyswrr3j6fhllhlsxyqw7sw4xi

Novel Back Propagation Optimization by Cuckoo Search Algorithm

Jiao-hong Yi, Wei-hong Xu, Yuan-tao Chen
2014 The Scientific World Journal  
In CSBP, CS is used to simultaneously optimize the initial weights and bias of BP network.  ...  The traditional Back Propagation (BP) has some significant disadvantages, such as training too slowly, easiness to fall into local minima, and sensitivity of the initial weights and bias.  ...  Comprehensively considering, the discovery rate is set to 0.1 in our paper. The Scientific World Journal  ... 
doi:10.1155/2014/878262 pmid:25028682 pmcid:PMC3980988 fatcat:amfb2rbc5jeihps2gqoxwf73ku

Mapping the development of research on physical activity and the built environment

Jenine K. Harris, Jesse Lecy, J. Aaron Hipp, Ross C. Brownson, Diana C. Parra
2013 Preventive Medicine  
These weights represent the proportion of all paths through the network that contain a specific node or link (De Nooy, et al, 2011) , so a traversal weight of .1 would indicate an article is on 10% of  ...  the citation paths through the network.  ...  The progression from scientific discovery to delivery of interventions is fundamental in public health (Harris, et al, 2009 ).  ... 
doi:10.1016/j.ypmed.2013.07.005 pmid:23859932 pmcid:PMC4157726 fatcat:qdnz7f5gdzeqpov5dneo5szele

The Effect of Using Independent Learning (Discovery - Individual) on the Level of Skill Performance among Students of Swimming Specialty- Al Azhar University

Basem Saed Abdul Azim Muhammad
2020 Assiut Journal of Sport Science and Arts  
Moderation of the research sample distribution Table ( 1) shows that the skew coefficient for the variables (age -height -weight -intelligence -skill) ranged between (-12.  ...  the study sample.  ...  24-Nahid Khairy Abdullah Fayyad (1998 AD): "The effect of using the two teaching methods of directed and traditional discovery in the physical education lesson on the level of performance of some motor  ... 
doi:10.21608/ajssa.2020.147611 fatcat:yve6acvhfjdhdgzmk3s7nfn5ca

Natural Products in Drug Discovery [chapter]

Akshada Amit Koparde, Rajendra Chandrashekar Doijad, Chandrakant Shripal Magdum
2019 Pharmacognosy - Medicinal Plants [Working Title]  
Only natural product drug discovery plays an important role to develop the scientific evidence of these natural resources.  ...  Research in drug discovery needs to develop robust and viable lead molecules, which step forward from a screening hit to a drug candidate through structural elucidation and structure identification through  ...  various scientific process for various scientific investigations and study of herbal drug discovery.  ... 
doi:10.5772/intechopen.82860 fatcat:3jvkkvuwiffetc62f3g67euu7y

Meteorites as a Scientific Heritage
Os Meteoritos como Património Cientifico

Annarita Franza, Giovanni Pratesi
2020 Conservar Património  
This paper investigates the importance of meteorites as a scientific heritage.  ...  This work outlines the structure of the catalogue card that describes the meteorite specimen along with other information related to the sample (e.g., archival documentation on collectors and traders,  ...  Finally, we thank the Fondazione Cassa di Risparmio di Firenze for providing the financial support to successfully complete this article through the fund MECSO "Meteoroid Characterization through Spectroscopic  ... 
doi:10.14568/cp2020018 fatcat:3pitjxmzwfdhxiig4xsvefztbe

Computational optimisation of targeted DNA sequencing for cancer detection

Pierre Martinez, Nicholas McGranahan, Nicolai Juul Birkbak, Marco Gerlinger, Charles Swanton
2013 Scientific Reports  
Dividing 4,467 samples into one discovery and two independent validation cohorts, we show that up to 76% of 10 cancer types harbour at least one mutation in a panel of only 25 genes, with high sensitivity  ...  Samples were weighted according to the occurrence of each tumour type and the number of samples in each set.  ...  Weighting genes by size allowed the exclusion of large genes such as TTN and MUC16 (respectively 107976 and 43524 bp, mutated in 44.0% and 24.3% of the discovery samples), where mutations are more likely  ... 
doi:10.1038/srep03309 pmid:24296834 pmcid:PMC6506443 fatcat:cntcfyvh45avzk3bc7mgg264w4

A Field Guide to Scientific XAI: Transparent and Interpretable Deep Learning for Bioinformatics Research [article]

Thomas P Quinn, Sunil Gupta, Svetha Venkatesh, Vuong Le
2021 arXiv   pre-print
Rather, many scientific models are developed to facilitate scientific discovery, by which we mean to abstract a human-understandable representation of the natural world.  ...  Unfortunately, the opacity of deep neural networks limit their role in scientific discovery, creating a new demand for models that are transparently interpretable.  ...  We use the term scientific XAI to refer to the use of XAI for scientific discovery.  ... 
arXiv:2110.08253v1 fatcat:xghw4z53fvbivkzqp3aczlbpky

The Virtuous Cycle of a Data Ecosystem

Bradley Voytek, Philip E. Bourne
2016 PLoS Computational Biology  
Large, multidimensional datasets-rich with hidden information-are reduced to summary statistics filtered through limitations imposed by contemporary methods and technologies, and through the biased lens  ...  Raw scientific data, when they are published at all, are provided in a very limited form.  ...  Text mining for scientific discovery.  ... 
doi:10.1371/journal.pcbi.1005037 pmid:27490108 pmcid:PMC4974004 fatcat:5j7vqiitezc4rf2it6d7twzx3y

From sample to knowledge: Towards an integrated approach for neuroscience discovery [article]

William Gray Roncal, Eva L Dyer, Doga Gürsoy, Konrad Kording, Narayanan Kasthuri
2017 arXiv   pre-print
We thus advocate for the development of sample-to-knowledge discovery pipelines that one can use to optimize acquisition and processing steps with a particular end goal (i.e., piece of knowledge) in mind  ...  To illustrate this approach, we provide an experimental paradigm to answer questions about large-scale synaptic distributions through a multimodal approach combining X-ray microtomography and electron  ...  Introduction Much of scientific exploration involves three main stages to translate raw data to knowledge suitable for making scientific discoveries: acquisition, processing, and analysis.  ... 
arXiv:1604.03199v2 fatcat:6kei7mopvzbkboe7qxggibhhyy

AutoDrug: fully automated macromolecular crystallography workflows for fragment-based drug discovery

Yingssu Tsai, Scott E. McPhillips, Ana González, Timothy M. McPhillips, Daniel Zinn, Aina E. Cohen, Michael D. Feese, David Bushnell, Theresa Tiefenbrunn, C. David Stout, Bertram Ludaescher, Britt Hedman (+2 others)
2013 Acta Crystallographica Section D: Biological Crystallography  
This workflow was run once on the same 96 samples that the group had examined manually and the workflow cycled successfully through all of the samples, collected data from the same samples that were selected  ...  A workflow tailored to mimic the crystallography stages comprising the drug-discovery pipeline of CoCrystal Discovery Inc. has been deployed and successfully demonstrated.  ...  The workflow specified by CoCrystal Discovery, from sample screening and selection through electron-density map analysis, was successfully automated and carried out by AutoDrug.  ... 
doi:10.1107/s0907444913001984 pmid:23633588 pmcid:PMC3640469 fatcat:sszlzgdi35bnvpqaixbmydtqxi

Blood-Based Biomarker Candidates of Cerebral Amyloid Using PiB PET in Non-Demented Elderly

Sarah Westwood, Emanuela Leoni, Abdul Hye, Steven Lynham, Mizanur R. Khondoker, Nicholas J. Ashton, Steven J. Kiddle, Alison L. Baird, Ricardo Sainz-Fuertes, Rufina Leung, John Graf, Cristina Tan Hehir (+7 others)
2016 Journal of Alzheimer's Disease  
In order to seek such a candidate biomarker, discovery phase proteomic analyses using 2DGE and gel-free LC-MS/MS for high and low molecular weight analytes were conducted on longitudinal plasma samples  ...  Having a blood-based marker that would reduce such costs and accelerate clinical trials through identifying potential participants with likely pre-clinical AD would be a substantial advance.  ...  Plasma samples from a subset of 25 of these subjects, matched for age and gender, were further analyzed for the discovery of low molecular weight proteins as biomarkers (discovery phase 2).  ... 
doi:10.3233/jad-151155 pmid:27031486 pmcid:PMC5898378 fatcat:kxy2tmcomrgltjwnipt63uigvu

Problem Solving Heuristic to Develop Scientific Reasoning

Hasri Arlin Wuriyudani, Wiyanto Wiyanto, Teguh Darsono
2018 Physics Communication  
The samples are 32 students in junior high school at 11-13 years old. The methods are CTSR test of scientific reasoning by Lawson and interview. The research design is one grup pretest-posttest.  ...  The aim of this research is knowing the influence of heuristic problem solving method that has been designed on practicum sheet of discovery learning model to develop scientific reasoning of students.  ...  Scientific reasoning ability can be developed with implementation of heuristic methods on discovery learning models.  ... 
doi:10.15294/physcomm.v3i1.15022 fatcat:6llcw5srvjh2thnitw45ex335y

Research Data Management and Preservation

Teo Redondo
2021 Zenodo  
Risk assessment data; other sample data Key: LABDRIVE Competences Patel, Manjula. / I2S2 Idealised Scientific Research Activity Lifecycle Model. 2011. 3 p.  ...  Risk assessment data; other sample data Key: • Open access to scientific publications to be ensured • Open access to research data to be ensured in line with principle 'as open as possible, as  ... 
doi:10.5281/zenodo.5075037 fatcat:mirchj75engzlb42zinirgs7ai

Costa Rican International Cooperative Biodiversity Group: Using Insects And Other Arthropods In Biodiversity Prospecting

A. Sittenfeld, G. Tamayo, V. Nielsen, A. Jiménez, P. Hurtado, M. Chinchilla, O. Guerrero, M. A. Mora, M. Rojas, R. Blanco, E. Alvarado, J. M. Guttiérrez (+1 others)
1999 Pharmaceutical Biology  
Tables 1 and 2 show the information on fresh weight, dry weight (weight of the insect sample after lyophilization), and water content for 863 insect samples obtained from 19 different insect orders.  ...  Fresh weight, dry weight and water content as percentage (%) of insect 1 samples according to different orders.  ... 
doi:10.1076/1388-0209(200010)37:sup;1-w;ft055 fatcat:b663ulvj35cdpotbmkaf5xzznu
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