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Entrepreneurship and Bank Credit Availability
2002
Journal of Finance
Focal Cortical Atrophy Syndromes
1996
Brain and Cognition
Atypical cases have also been reported presenting with primary cognitive impairment (Bergeron, Pollanen, Weyer, Black, & Lang, 1996) . ...
., 1981; Riley, Lang, Lewis, Resch, Ashby, Hornykiewicz, & Black, 1990; Thompson & Marsden, 1992; Rinne, Lee, Thompson, & Marsden, 1994) . ...
doi:10.1006/brcg.1996.0042
pmid:8811996
fatcat:zy2n2v6qqrbfvjkdgqpanymymy
Toward Wisdom From Failure
2002
Stroke
Background-Neuroprotective drugs for acute stroke have appeared to work in animals, only to fail when tested in humans. With the failure of so many clinical trials, the future of neuroprotective drug development is in jeopardy. Current hypotheses and methodologies must continue to be reevaluated, and new strategies need to be explored. Summary of Review-In part 1, we review key challenges and complexities in translational stroke research by focusing on the "disconnect" in the way that
doi:10.1161/01.str.0000025518.34157.51
pmid:12154275
fatcat:3szf2ryd7zay5nkirnp2w6u3ly
more »
... ctive agents have traditionally been assessed in clinical trials compared with animal models. In preclinical studies, determination of neuroprotection has relied heavily on assessment of infarct volume measurements (instead of functional outcomes), short-term (instead of long-term) end points, transient (instead of permanent) ischemia models, short (instead of extended) time windows for drug administration, and protection of cerebral gray matter (instead of both gray and white matter). Clinical trials have often been limited by inappropriately long time windows, insufficient statistical power, insensitive outcome measures, inclusion of protocol violators, failure to target specific stroke subtypes, and failure to target the ischemic penumbra. In part 2, we explore new concepts in ischemic pathophysiology that should encourage us also to think beyond the hyperacute phase of ischemia and consider the design of trials that use multiagent therapy and exploit the capacity of the brain for neuroplasticity and repair. Conclusions-By recognizing the strengths and limitations of animal models of stroke and the shortcomings of previous clinical trials, we hope to move translational research forward for the development of new therapies for the acute and subacute stages after stroke. (Stroke. 2002;33:2123-2136.)
Recent Developments in Intergenerational Mobility
[chapter]
2011
Handbook of Labor Economics
Child endowments are assumed to follow an AR(1) process; 1 0 1 v e e , (8) where is between 0 and 1 and v is white noise. ...
In Black, Devereux, and Salvanes (2005) , we apply this approach using register data from Norway. ...
doi:10.1016/s0169-7218(11)02414-2
fatcat:jceq4k3jlvclfhkjbqw4f5gv2y
Diagnosing dementia
2016
CMAJ - Canadian Medical Association Journal
This Help Sheet provides information about the early signs of dementia, the techniques used to diagnose dementia and the importance of an early and correct diagnosis. What are the early signs of dementia? Because the diseases that cause dementia develop gradually, the early signs may be very subtle and not immediately obvious. Early symptoms also depend on the type of dementia and vary a great deal from person to person. Common early symptoms include: • Memory problems, particularly remembering
doi:10.1503/cmaj.150508
pmid:27067820
pmcid:PMC4868610
fatcat:jvfawfge6zab5m5235disxsiee
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... recent events • Increasing confusion • Reduced concentration
Attentional networks in normal aging and Alzheimer's disease
2006
Neuropsychology
The basic display was visible at all times and consisted of two black rectangular boxes and a black fixation cross against a gray background. ...
memory load modulations (Baddeley et al., 1999; Fernandez-Duque & Black, 2006a) . ...
doi:10.1037/0894-4105.20.2.133
pmid:16594774
fatcat:a262iylenfglvfqzdegoqptn7y
How Workers Fare When Employers Innovate
2004
Industrial Relations
This last finding is consistent with establishment productivity; Black and Lynch (2001) found higher productivity in unionized establishments that had a higher proportion of workers meeting. ...
Other factors that appear to be associated with the adoption of HPW practices include the education of the workforce (Black, Krivelyova, Lynch (2001)), the participation of the business in local employer ...
doi:10.1111/j.0019-8676.2004.00318.x
fatcat:3x5q6selu5fztchj7r6gjytuxe
Coronary Artery Calcification
2016
Journal of the American College of Cardiology
In the present study, black men and women had lower levels of CAC, consistent with previous ...
Sandra E. Black, Cognitive Neurology, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room A4 21, Toronto, Ontario M4N 3M5, Canada. ...
In the present study, black men and women had lower levels of CAC, consistent with previous SEE PAGE 1013 *Editorials published in the Journal of the American College of Cardiology reflect the views of ...
doi:10.1016/j.jacc.2016.01.007
pmid:26940920
fatcat:553bg5aetzaqfc4en7id6vcgty
Metacognitive judgment and denial of deficit
2007
Judgment and Decision Making
Words were displayed in Courier New 36 point against a black background. Procedure. ...
The timing of the stimulus display and data collection were managed using E-prime, a commercial experiment application. Data were collected via a microphone and response box. Stimuli. ...
doaj:e157f2fab1584bc0a68f734bfc043313
fatcat:mgxk5ve3mnb4rjiecci6kes6si
CADASIL accelerated by acute hypotension
2017
Neurology
Sandra E. Black: study concept and design, acquisition of data, critical revision of manuscript for intellectual content. ...
reveals multiple acute-on-chronic infarcts on diffusion-weighted imaging (DWI) (A, B) and fluid-attenuated inversion recovery (FLAIR) (C) images after a first hypotensive episode and on DWI (D, E) and ...
doi:10.1212/wnl.0000000000003717
pmid:28202707
pmcid:PMC5384836
fatcat:qoel3hrx5bftphc555h62u6dhy
Somatosensory Gating and Recovery From Stroke Involving the Thalamus
2002
Stroke
and Purpose-In the undamaged brain, sensory input to the cortex is intricately controlled via sensory gating mechanisms. Given the role of corticothalamic pathways in this control, it was hypothesized that in patients recovering from thalamic stroke there would be evidence of disrupted sensory gating and that efficient control of cortical sensory inputs would emerge during recovery. Methods-Four patients were tested serially after stroke from 1 to 24 weeks after injury. Perceptual thresholds,
doi:10.1161/01.str.0000032552.40405.40
pmid:12411655
fatcat:7vedobx72fgb3bo7vpkpvznwxu
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... matosensory evoked potential amplitudes, and functional MRI activations under specific somatosensory stimulation conditions were measured. Results-All patients demonstrated comparable results, revealing disrupted threshold detection to vibrotactile stimuli in the presence of a concurrent competing, contralateral input. In contrast, threshold detection was comparable between the affected and unaffected sides when there were no competing stimuli. This compromised capacity to inhibit competing sensory inputs was paralleled by a reduction in the measured activation of cortical representation in the stroke-affected hemisphere (functional MRI and somatosensory evoked potential) during bilateral stimulation. After recovery, perceptual detection improvements during bilateral stimulation were paralleled by enhancements of primary somatosensory cortical activation in the stroke-affected hemisphere. Conclusions-These results provide insight into potential mechanisms that contribute to sensory gating and suggest that the ability to control sensory input through effective gating mechanisms, in addition to primary somatosensory representation, may be important for poststroke sensory recovery. (Stroke. 2002;33:2642-2651.)
Apply Yourself: Racial and Ethnic Differences in College Application
2018
Education Finance and Policy
The effect is particularly large for Asian and black students. ...
white students, largely due to the presence of historically black universities. ...
doi:10.1162/edfp_a_00273
fatcat:ruyodfuj3vfnpks7k4vsnlmecm
Remote spatial memory in an amnesic person with extensive bilateral hippocampal lesions
2000
Nature Neuroscience
Despite his severe amnesia for autobiographical knowledge, E C . performed nomally on a wide range of spatial tests of his neighbourhood and the world which included: 1. naturai navigation in his wighbourhood ...
' O& To assess M e r K.C.' ...
The Extent of Wp-poc-
Involv-
Remte S
m Memay
McLachian, & Moscovitch, 1988; Tuiving et al-, 199 1 ; Kahler, Black, Levine, & Tdving, 1 994) because his amnesia is relatively pure. ...
doi:10.1038/79867
pmid:11017178
fatcat:o7qietdnzrgdbc7i4q5igetndq
Hemispatial Neglect and Visual Search: A Large Scale Analysis
2004
Cortex
E. ...
Black and by a University of Toronto Open Scholarship to Patricia Ebert. ...
Performance is scored out of 100 (Black et al., 1990; Leibovitch et al., 1998) . ...
doi:10.1016/s0010-9452(08)70120-5
pmid:15156783
fatcat:y4dlqg7d6ngrjaadarqcazpkrq
Small Family, Smart Family?
2010
The Journal of human resources
In recent work (Black, Devereux and Salvanes 2005) , we use Norwegian data on cohorts born between 1912 and 1975 and variation in family size induced by the birth of twins to examine the effects of family ...
is 17 Recent papers have found that the impacts of birth weight on adult outcomes are generally similar in magnitude in the cross-section to when twin or sibling differences are used in estimation [Black ...
doi:10.3368/jhr.45.1.33
fatcat:dahwoszfnja7fj2t5qoqd2enti
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